Natural Product Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Three new metabolites from the endophyte Fusarium proliferatum T2-10
Nat Prod Res. 2023 Nov 7:1-11. doi: 10.1080/14786419.2023.2278158. Online ahead of print.ABSTRACTOne new cyclopeptide, cyclo-(L-Trp-L-Phe-L-Phe) (1), one new 2-pyridone derivative, fusarone A (3), and one new natural indole derivative, ethyl 3-indoleacetate (4), along with six known compounds were isolated from the endophytic fungus Fusarium proliferatum T2-10. The planar structures of three new compounds were identified by spectral methods including 1D and 2D NMR techniques, and the absolute configuration of compound 1 was elucidated by Marfey-MS method. In addition, all compounds were evaluated for their cytotoxic and an...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Jian-Bing Tan Wei-Wei Peng Mei-Fang Li Feng-Hua Kang Yu-Ting Zheng Li Xu Si-Yu Qin Yuan-Tao Huang Zhen-Xing Zou Source Type: research

Bioactive compounds by UHPLC-MS/MS and molecular networking from Myrceugenia foveolata 
Nat Prod Res. 2023 Nov 7:1-5. doi: 10.1080/14786419.2023.2278162. Online ahead of print.ABSTRACTMyrceugenia foveolata, commonly known as 'guamirim', was analysed using UHPLC-MS/MS and molecular networking. Hydroalcoholic extracts of leaves and stem bark were obtained using ethanol:water (70:30) as solvent. Chemical composition of the extracts was identified using UHPLC-MS/MS and tested for antioxidant activity and growth inhibition against E. coli, S. aureus, L. monocytogenes and S. enterica. Ten compounds were tentatively identified in the extracts including myricitrin, quercitrin, and betulin (in leave extracts), and avi...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Matheus H O de Sousa Marta S D Freitas Karina Cesca Eduardo J Pilau Carla Porto Neusa F de Moura Source Type: research

Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans 
Nat Prod Res. 2023 Nov 7:1-6. doi: 10.1080/14786419.2023.2278164. Online ahead of print.ABSTRACTThe chemical composition of the essential oil of Lindera subumbelliflora (Lauraceae) was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterised by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The antifungal activity of L. subumbelliflora essential oil was tested against Candida albicans and Streptococcus mutans using the broth microdilution assay, whereas the microbial biofilms were determined using a semi-quantitative static biofilm. A total of 2...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Nur Nabilah Mohd Zaini Wan Mohd Nuzul Hakimi Wan Salleh Mohd Hafiz Arzmi Abubakar Siddiq Salihu Nurunajah Ab Ghani Source Type: research

The chemical composition of the aerial parts essential oil of Pulicaria odora (L.) Rchb. growing in Sicily (Italy)
Nat Prod Res. 2023 Nov 7:1-7. doi: 10.1080/14786419.2023.2278170. Online ahead of print.ABSTRACTThe genus Pulicaria Gaertn. (Asteraceae) comprises more than ninety-two species as annual or perennial herbs or small shrubs, distributed in Africa, Europe, and Asia, and concentrated mainly in the Mediterranean region. Several species have been used in the traditional medicine of many countries. In the present study the chemical composition of the essential oil from aerial parts of Pulicaria odora (L.) Rchb., present in the Mediterranean region and collected in Sicily, was analysed by GC-MS. No papers have been previously publi...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Francesco Sgadari Alessandro Vaglica Antonella Porrello Alessandro Crisafulli Rosario Schicchi Maurizio Bruno Source Type: research

Centaurea polyacantha and C. maroccana: the chemical composition of the aerial parts essential oils of these Centaurea species (Asteraceae) collected in Morocco
Nat Prod Res. 2023 Nov 7:1-10. doi: 10.1080/14786419.2023.2278757. Online ahead of print.ABSTRACTIn the present study, the chemical composition of the essential oil from the aerial parts of two Centaurea species not previously investigated, C. polyacantha Willd. (sect. Seridia, Asteraceae) and C. maroccana Ball. (sect. Calcitrapa, Asteraceae), collected in Morocco, was evaluated by GC-MS. The main components of the essential oil of the first one were limonene (18.2%), β-bisabolene (11.5%), (Z)-β-farnesene (8.6%), and spathulenol (8.3%), whereas the C. maroccana essential oil, practically devoid of terpenoids, was shown t...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Natale Badalamenti Gianfranco Fontana Maurizio Bruno Vincenzo Ilardi Source Type: research

Two new Aspera chaetominines A and B, and a new derivative of terrein, isolated from marine sponge associated fungus Aspergillus versicolour SCSIO XWS04 F52
Nat Prod Res. 2023 Nov 7:1-13. doi: 10.1080/14786419.2023.2275744. Online ahead of print.ABSTRACTTwo new alkaloids, Aspera chaetominines A (1) and B (2), a new derivative (3) of terrein, and together with 11 known compounds (4-14) were isolated from marine sponge Callyspongia sp. -derived fungus Aspergillus versicolour SCSIO XWS04 F52, which was identified on the basis of morphology and ITS sequence analysis. The planar structures of 1-3 were determined by spectroscopic (1H, 13C NMR, HSQC, HMBC, and 1H-1H COSY), and MS analysis. Compounds 1 and 2 showed cytotoxic activity against leukaemia K562 and colon cancer cells SW111...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Mangaladoss Fredimoses Wen Ai Xiuping Lin Xuefeng Zhou Shengrong Liao Li Pan Yonghong Liu Source Type: research

Antifungal activity of citronellal against Trichophyton rubrum and its predictive mechanism of action by CYP51 inhibition through molecular docking
Nat Prod Res. 2023 Nov 7:1-9. doi: 10.1080/14786419.2023.2277352. Online ahead of print.ABSTRACTThe present study aimed to investigate the antifungal activity of citronellal (CIT) against clinical isolates of T. rubrum and to show the possible mechanism of action involved. The antifungal potential of CIT was evaluated from the Minimum Inhibitory Concentration (MIC), Minimum Fungicide Concentration (MFC) and assays with ergosterol and sorbitol, to elucidate the possible mechanisms of action, and molecular docking. MIC and MFC values ranged from 4 to 512 µg/mL. Regarding the mechanism of action, the monoterpene demonstrated...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Francisco Patricio de Andrade J únior Rawny Galdino Gouveia C ássio Ilan Soares Medeiros Br áulio de Almeida Teixeira Brenda Kercya da Silva Farias Nayana da Rocha Oliveira Daniele de Figuer êdo Silva Edeltrudes de Oliveira Lima Source Type: research

Powerful antioxidants within Cupressus arizonica Greene female cones and leaves essential oil
Nat Prod Res. 2023 Nov 7:1-10. doi: 10.1080/14786419.2023.2278157. Online ahead of print.ABSTRACTThe composition and antioxidant activity of the essential oil obtained from the female cones and leaves of Cupressus arizonica were assessed using the DPPH assay. The total oil yields obtained through hydrodistillation from the female cones and leaves were 1.9% (v/w) and 0.65% (v/w), respectively. The GC-MS chemical analysis of the oils from the female cones and leaves resulted in the identification of 17 and 45 compounds, respectively. Moreover, the essential oils obtained from C. arizonica female cones were predominantly comp...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: Seyyed Khalil Hosseinihashemi Fatemeh Barzegari Hadi Baseri Luiz Claudio Almeida Barbosa Source Type: research

Experimental studies on thermal and FTIR characterisation of bio-degradable neat neem gum and epoxy resin for composite material applications
This article aims to assess the suitability of natural neem gum in various composite material applications in place of epoxy resin. The assessment was done by thermal characterisation, experimental study and comparative analysis of thermal behaviour, Fourier transform IR spectroscopy (FTIR) characterisation and comparison of functional groups and mechanical properties of neat epoxy and neat neem resins. To study and compare thermal behaviour differential scanning calorimetry (DSC), thermogravimetric (TG) and relative derivative TG (DTG) analysis were conducted. The glass transition temperatures, exothermic and endothermic ...
Source: Natural Product Research - November 7, 2023 Category: Biochemistry Authors: G SundaraPandian Arunachalam K Source Type: research

Arginase inhibitory activities of chemical constituents from Macaranga hurifolia Beille leaves
Nat Prod Res. 2023 Nov 5:1-6. doi: 10.1080/14786419.2023.2275267. Online ahead of print.ABSTRACTThe methanolic extract of the leaves of Macaranga hurifolia Beille showed arginase inhibitory activity (40% at 100 µg/mL) and was then fractionated to obtain nine polyphenolic compounds. Their structures were elucidated on the basis of NMR spectroscopic data, and by comparison with data previously reported in the literature, as gallic acid (1), 3,4-dihydroxybenzoic acid (2), chlorogenic acid, (3), corilagin (4), cynaroside (5), cosmosiin (6), hyperoside (7) isoquercitrin (8) and guajaverin (9). These compounds have been evaluat...
Source: Natural Product Research - November 6, 2023 Category: Biochemistry Authors: Andy Zedet Yao Kanga Marc Pudlo Fran çois Senejoux Corine Girard Source Type: research