Phytochemical analysis, antibacterial and antifungal effect of < em > Lavandula dentata < /em > L. essential oil and methanol extract
Nat Prod Res. 2023 Sep 1:1-10. doi: 10.1080/14786419.2023.2252973. Online ahead of print.ABSTRACTThe aim of this study was to analyse the essential oil of Lavandula dentata from Algeria and to test the antioxidant and antimicrobial properties of this plant. The essential oil (EO) (57 constituents) included mainly α-pinene, β-pinene, nopinone, linalool, cryptone, and limonene. The plant polyphenolic contents and the antioxidant activity were determined. The antimicrobial effect of the EO and the methanolic extract (ME) was assessed against referenced and clinical bacterial strains, and also foodborne fungal isolates. The ...
Source: Natural Product Research - September 1, 2023 Category: Biochemistry Authors: Noui Hendel Madani Sarri Djamel Sarri Soumia Seghiour Edoardo Napoli Mounir Selloum Giuseppe Ruberto Source Type: research

Antitumor and chemopreventive role of major phytochemicals against breast cancer development
We examined current knowledge of their bioavailability, safety and modulation of molecular mechanisms including their ability to induce apoptotic cell death, promote cell cycle arrest, and inhibit cellular proliferation in different breast cancer cell lines and in vivo models. This review emphasises the importance of these naturally occurring phytochemicals and their potential of becoming therapeutic options in the arsenal against breast cancer development provided further scientific and clinical validation.PMID:37646820 | DOI:10.1080/14786419.2023.2251167 (Source: Natural Product Research)
Source: Natural Product Research - August 30, 2023 Category: Biochemistry Authors: Matthew Schwarztrauber Nathaniel Edwards James Hiryak Ritesh Chandrasekaran Jayson Wild Ajay Bommareddy Source Type: research

Phytochemical, antileishmanial, antifungal and cytotoxic profiles of < em > Thymelaea tartonraira < /em > (L.) All. extracts
Nat Prod Res. 2023 Aug 30:1-7. doi: 10.1080/14786419.2023.2252153. Online ahead of print.ABSTRACTExtracts from leaves and stems of Thymelaea tartonraira (L.) All. growing in Tunisia were characterised for the presence of flavonoids and phenolic acids by LC-ESI-MS analysis. Twelve flavonoids and ten phenolic acids were detected for the first time in the aerial parts of this plant species, the most abundant compounds being gallic acid, kaempferol, catechin, chlorogenic acid, naringenin and acacetin. The extracts were subjected to in vitro antileishmanial, antifungal and cytotoxic assays, showing promising antileishmanial act...
Source: Natural Product Research - August 30, 2023 Category: Biochemistry Authors: Siwar Soltani Imed Koubaa Sandrine Cojean Carine Picot Pascal Marchand Noureddine Allouche Source Type: research

Effects of inoculation of corn silage with < em > Saccharomyces cerevisiae < /em > on silage fermentation characteristics, nutrient digestibility, mycoflora and aflatoxin production
Nat Prod Res. 2023 Aug 30:1-10. doi: 10.1080/14786419.2023.2252154. Online ahead of print.ABSTRACTIn the present study, fresh whole corn plants along with half milk kernels line were treated with live and hydrolysed yeast with different concentrations before ensiling and kept in airtight bags and then into mini silos in order to achieve anaerobic conditions for proper fermentation. The buckets were opened after different time intervals to characterise the material, quick acidification, dry matter recovery, and aerobic stability of silage respectively. Moreover, mycoflora and aflatoxin contamination were also analysed. The ...
Source: Natural Product Research - August 30, 2023 Category: Biochemistry Authors: Anum Javed Maryam Ajmal Nafeesa Qudsia Hanif Abida Akram Source Type: research

Antitumor and chemopreventive role of major phytochemicals against breast cancer development
We examined current knowledge of their bioavailability, safety and modulation of molecular mechanisms including their ability to induce apoptotic cell death, promote cell cycle arrest, and inhibit cellular proliferation in different breast cancer cell lines and in vivo models. This review emphasises the importance of these naturally occurring phytochemicals and their potential of becoming therapeutic options in the arsenal against breast cancer development provided further scientific and clinical validation.PMID:37646820 | DOI:10.1080/14786419.2023.2251167 (Source: Natural Product Research)
Source: Natural Product Research - August 30, 2023 Category: Biochemistry Authors: Matthew Schwarztrauber Nathaniel Edwards James Hiryak Ritesh Chandrasekaran Jayson Wild Ajay Bommareddy Source Type: research

Phytochemical, antileishmanial, antifungal and cytotoxic profiles of < em > Thymelaea tartonraira < /em > (L.) All. extracts
Nat Prod Res. 2023 Aug 30:1-7. doi: 10.1080/14786419.2023.2252153. Online ahead of print.ABSTRACTExtracts from leaves and stems of Thymelaea tartonraira (L.) All. growing in Tunisia were characterised for the presence of flavonoids and phenolic acids by LC-ESI-MS analysis. Twelve flavonoids and ten phenolic acids were detected for the first time in the aerial parts of this plant species, the most abundant compounds being gallic acid, kaempferol, catechin, chlorogenic acid, naringenin and acacetin. The extracts were subjected to in vitro antileishmanial, antifungal and cytotoxic assays, showing promising antileishmanial act...
Source: Natural Product Research - August 30, 2023 Category: Biochemistry Authors: Siwar Soltani Imed Koubaa Sandrine Cojean Carine Picot Pascal Marchand Noureddine Allouche Source Type: research

Effects of inoculation of corn silage with < em > Saccharomyces cerevisiae < /em > on silage fermentation characteristics, nutrient digestibility, mycoflora and aflatoxin production
Nat Prod Res. 2023 Aug 30:1-10. doi: 10.1080/14786419.2023.2252154. Online ahead of print.ABSTRACTIn the present study, fresh whole corn plants along with half milk kernels line were treated with live and hydrolysed yeast with different concentrations before ensiling and kept in airtight bags and then into mini silos in order to achieve anaerobic conditions for proper fermentation. The buckets were opened after different time intervals to characterise the material, quick acidification, dry matter recovery, and aerobic stability of silage respectively. Moreover, mycoflora and aflatoxin contamination were also analysed. The ...
Source: Natural Product Research - August 30, 2023 Category: Biochemistry Authors: Anum Javed Maryam Ajmal Nafeesa Qudsia Hanif Abida Akram Source Type: research

A comparative study on essential oils from the leaves and stems of Vietnamese < em > Mikania micrantha < /em > Kunth
In this study, the essential oils from leaves and stems of M. micrantha were extracted by hydrodistillation method, and the chemical profiles of essential oils were then analysed by gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC/MS). It was found that there were similarities and differences in chemical compositions and their percentage between the essential oils obtained from these two parts. The dominant components of leaves essential oil are β-Cubebene, Germacrene D, and α-Zingiberene, accounting for 11.34%, 10.96%, and 10.76%, respectively. Additionally, the major components of stems...
Source: Natural Product Research - August 28, 2023 Category: Biochemistry Authors: Quoc Trung Nguyen Khanh Ly Huynh Thi Minh Phuc Nguyen Thien Trinh Ngoc Thach Pham Minh Nhut Ho Yen Nhi Tran Thi Ngoc Quyen Tran Phuong Le Thi Source Type: research

A comparative study on essential oils from the leaves and stems of Vietnamese < em > Mikania micrantha < /em > Kunth
In this study, the essential oils from leaves and stems of M. micrantha were extracted by hydrodistillation method, and the chemical profiles of essential oils were then analysed by gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC/MS). It was found that there were similarities and differences in chemical compositions and their percentage between the essential oils obtained from these two parts. The dominant components of leaves essential oil are β-Cubebene, Germacrene D, and α-Zingiberene, accounting for 11.34%, 10.96%, and 10.76%, respectively. Additionally, the major components of stems...
Source: Natural Product Research - August 28, 2023 Category: Biochemistry Authors: Quoc Trung Nguyen Khanh Ly Huynh Thi Minh Phuc Nguyen Thien Trinh Ngoc Thach Pham Minh Nhut Ho Yen Nhi Tran Thi Ngoc Quyen Tran Phuong Le Thi Source Type: research

A comparative study on essential oils from the leaves and stems of Vietnamese < em > Mikania micrantha < /em > Kunth
In this study, the essential oils from leaves and stems of M. micrantha were extracted by hydrodistillation method, and the chemical profiles of essential oils were then analysed by gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC/MS). It was found that there were similarities and differences in chemical compositions and their percentage between the essential oils obtained from these two parts. The dominant components of leaves essential oil are β-Cubebene, Germacrene D, and α-Zingiberene, accounting for 11.34%, 10.96%, and 10.76%, respectively. Additionally, the major components of stems...
Source: Natural Product Research - August 28, 2023 Category: Biochemistry Authors: Quoc Trung Nguyen Khanh Ly Huynh Thi Minh Phuc Nguyen Thien Trinh Ngoc Thach Pham Minh Nhut Ho Yen Nhi Tran Thi Ngoc Quyen Tran Phuong Le Thi Source Type: research

Simple two-step purification and characterisation of peroxidase from < em > Citrullus colocynthis < /em >
Nat Prod Res. 2023 Aug 25:1-10. doi: 10.1080/14786419.2023.2248644. Online ahead of print.ABSTRACTPeroxidase is a biotechnologically important enzyme. The purification of peroxidase from the root of Citrullus colocynthis was carried out in a simple two-step process with maximum purity level. The sample was extracted in a high salt buffer, and the enzyme was partially purified with a Q-Sepharose anion exchange column. Final purification was carried out with HighLoad 16/600 Superdex G-75 column. The purified protein was analysed with SDS gel electrophoresis, which suggested a single band of approximately 35 kDa. Further, the...
Source: Natural Product Research - August 25, 2023 Category: Biochemistry Authors: Malik Shoaib Ahmad Nayab Shah Zeeshan Akbar Tajwali Khan Arslan Ali Source Type: research

The chemical characterisation of nettle ( < em > Urtica dioica < /em > L.) seed oil
Nat Prod Res. 2023 Aug 25:1-8. doi: 10.1080/14786419.2023.2250525. Online ahead of print.ABSTRACTThe past decade has seen increasing interest in plant oils in the food, pharmaceutical, and cosmetic industries due to their diverse functional and nutritional properties, as well as the high levels of consumer acceptance. As a result, there has been a spike in research interest in finding new sources of oils with good potential for industrial use. In this paper, the chemical characterisation (saponification, iodine, acid and ester numbers, as well as fatty acid composition) of nettle seed oil was given. Oil was analysed for it...
Source: Natural Product Research - August 25, 2023 Category: Biochemistry Authors: Jelena Mitrovi ć Nada Nikoli ć Ivan Risti ć Ivana Karabegovi ć Sa ša Savić Olivera Šimurina Biljana Cvetkovi ć Mirjana Pe šić Source Type: research

The chemical composition of the aerial parts essential oil of < em > Stachys ocymastrum < /em > L. Briq. (Lamiaceae) growing in Sicily (Italy)
Nat Prod Res. 2023 Aug 25:1-7. doi: 10.1080/14786419.2023.2250515. Online ahead of print.ABSTRACTThe genus Stachys L. (Lamiaceae) comprises more than 300 species as annual or perennial herbs or small shrubs, spread in temperate regions of Mediterranean, Asia, America, and Southern Africa. Several species have been used in the traditional medicine to treat stress, skin inflammations, gastrointestinal disorders, asthma, and genital tumours. In the present study the chemical composition of the essential oil from aerial parts of Stachys ocymastrum L. Briq., belonging to section Olisia, endemic of the Western Mediterranean and ...
Source: Natural Product Research - August 25, 2023 Category: Biochemistry Authors: Alessandro Vaglica Antonella Porrello Natale Badalamenti Vincenzo Ilardi Maurizio Bruno Source Type: research

Simple two-step purification and characterisation of peroxidase from < em > Citrullus colocynthis < /em >
Nat Prod Res. 2023 Aug 25:1-10. doi: 10.1080/14786419.2023.2248644. Online ahead of print.ABSTRACTPeroxidase is a biotechnologically important enzyme. The purification of peroxidase from the root of Citrullus colocynthis was carried out in a simple two-step process with maximum purity level. The sample was extracted in a high salt buffer, and the enzyme was partially purified with a Q-Sepharose anion exchange column. Final purification was carried out with HighLoad 16/600 Superdex G-75 column. The purified protein was analysed with SDS gel electrophoresis, which suggested a single band of approximately 35 kDa. Further, the...
Source: Natural Product Research - August 25, 2023 Category: Biochemistry Authors: Malik Shoaib Ahmad Nayab Shah Zeeshan Akbar Tajwali Khan Arslan Ali Source Type: research

The chemical characterisation of nettle ( < em > Urtica dioica < /em > L.) seed oil
Nat Prod Res. 2023 Aug 25:1-8. doi: 10.1080/14786419.2023.2250525. Online ahead of print.ABSTRACTThe past decade has seen increasing interest in plant oils in the food, pharmaceutical, and cosmetic industries due to their diverse functional and nutritional properties, as well as the high levels of consumer acceptance. As a result, there has been a spike in research interest in finding new sources of oils with good potential for industrial use. In this paper, the chemical characterisation (saponification, iodine, acid and ester numbers, as well as fatty acid composition) of nettle seed oil was given. Oil was analysed for it...
Source: Natural Product Research - August 25, 2023 Category: Biochemistry Authors: Jelena Mitrovi ć Nada Nikoli ć Ivan Risti ć Ivana Karabegovi ć Sa ša Savić Olivera Šimurina Biljana Cvetkovi ć Mirjana Pe šić Source Type: research