Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology
With the incidence of hypertension increasing worldwide, more and more the mechanisms of hypertension from the perspective of immunity have found. Intestinal microbiota as well as its metabolites relationship ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - October 4, 2022 Category: Allergy & Immunology Authors: Ze-Jun Yang, Tian-Tian Wang, Bo-Ya Wang, Han Gao, Cheng-Wei He, Hong-Wei Shang, Xin Lu, Ying Wang and Jing-Dong Xu Tags: Review Source Type: research
Single-cell RNA-seq data analysis characterizing bronchoalveolar epithelial cells in patients with SARS-CoV-2 infection
Angiotensin-converting enzyme 2 (ACE2) has been reported to be the main receptor for SARS-CoV-2 infection of host cells. Understanding the changes in bronchoalveolar epithelial cells after SARS-CoV-2 infection... (Source: Journal of Inflammation)
Source: Journal of Inflammation - September 5, 2022 Category: Allergy & Immunology Authors: Zhiqin Deng, Qin Li, Yongshen Li, Zhenhan Deng, Xiaoqiang Chen, Zhe Zhao, Guganghui Wang, Daping Wang, Jianquan Liu and Wencui Li Tags: Research Source Type: research
SILAC-based quantitative proteomics to investigate the eicosanoid associated inflammatory response in activated macrophages
Macrophages play a central role in inflammation by phagocytosing invading pathogens, apoptotic cells and debris, as well as mediating repair of tissues damaged by trauma. In order to do this, these dynamic cel... (Source: Journal of Inflammation)
Source: Journal of Inflammation - September 1, 2022 Category: Allergy & Immunology Authors: Nicole Brace, Ian L. Megson, Adriano G. Rossi, Mary K. Doherty and Phillip D. Whitfield Tags: Research Source Type: research
Human monocytes differentiate into tumor-associated macrophages upon SKOV3 cells coculture and/or lysophosphatidic acid stimulation
Serous ovarian carcinoma is the most common type of ovarian carcinoma. Tumor-associated macrophages (TAMs) promote ovarian cancer progression. Most macrophages are generated by monocyte differentiation. Lysoph... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 16, 2022 Category: Allergy & Immunology Authors: Ying Feng, Meizhu Xiao, Guangming Cao, Hao Liu, Yanfang Li, Shuzhen Wang, Stan Zijtveld, Bert Delvoux, Sofia Xanthoulea, Andrea Romano, Chongdong Liu and Zhenyu Zhang Tags: Research Source Type: research
Recent evidence from omic analysis for redox signalling and mitochondrial oxidative stress in COPD
COPD is driven by exogenous and endogenous oxidative stress derived from inhaled cigarette smoke, air pollution and reactive oxygen species from dysregulated mitochondria in activated inflammatory cells within... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 11, 2022 Category: Allergy & Immunology Authors: Sharon Mumby and Ian M Adcock Tags: Review Source Type: research
Serinc2 deficiency causes susceptibility to sepsis-associated acute lung injury
Severe sepsis and its subsequent complications cause high morbidity and mortality rates worldwide. The lung is one of the most vulnerable organs sensitive to the sepsis-associated inflammatory storm and usuall... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 7, 2022 Category: Allergy & Immunology Authors: Shuai Mao, Jian Lv, Meng Chen, Ningning Guo, Yu Fang, Jingjing Tong, Xianghu He, Gang Wu and Zhihua Wang Tags: Research Source Type: research
Influenza a virus triggers acute exacerbation of chronic obstructive pulmonary disease by increasing proinflammatory cytokines secretion via NLRP3 inflammasome activation
In this study, we investigated the role of IAV induced NLRP3 ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 23, 2022 Category: Allergy & Immunology Authors: Shuang Ji, Meng-Yuan Dai, Yun Huang, Xiang-Chun Ren, Meng-Long Jiang, Jin-Ping Qiao, Wen-Ying Zhang, Yuan-Hong Xu, Ji-Long Shen, Ren-Quan Zhang and Guang-He Fei Tags: Research Source Type: research
Cigarette smoke extract-mediated FABP4 upregulation suppresses viability and induces apoptosis, inflammation and oxidative stress of bronchial epithelial cells by activating p38 MAPK/MK2 signaling pathway
Long-term inhalation of cigarette smoke is considered to be one of the main causes of bronchial epithelioid cell damage, but its underlying mechanism has to be further clarified. (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 15, 2022 Category: Allergy & Immunology Authors: Wei Zhang, Yibin Zhang and Qi Zhu Tags: Research Source Type: research
Key early proinflammatory signaling molecules encapsulated within circulating exosomes following traumatic injury
Assessment of immune status in critically ill patients is often based on serial tracking of systemic cytokine levels and clinical laboratory values. Exosomes are extracellular vesicles that can be secreted and... (Source: Journal of Inflammation)
Source: Journal of Inflammation - May 12, 2022 Category: Allergy & Immunology Authors: Sarah A. Walsh and Thomas A. Davis Tags: Research Source Type: research
Low density neutrophils are increased in patients with Beh çet’s disease but do not explain differences in neutrophil function
Beh çet’s disease (BD) is a multisystem autoinflammatory disease characterised by mucosal ulceration, ocular, neural, joint and skin inflammation. The cause of BD is not known but there is a strong genetic asso... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 31, 2022 Category: Allergy & Immunology Authors: Mariam Murad, Liying Low, Matthew Davidson, Philip I. Murray, Saaeha Rauz and Graham R. Wallace Tags: Research Source Type: research
CircRNA circFADS2 is under-expressed in sepsis and protects lung cells from LPS-induced apoptosis by downregulating miR-133a
This study was carried out... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 12, 2022 Category: Allergy & Immunology Authors: Fang Niu, Xiaofeng Liang, Jindi Ni, Zhuye Xia, Lijing Jiang, Hong Wang, Hongjie Liu, Guofeng Shen and Xiang Li Tags: Research Source Type: research
Prophylactic or therapeutic administration of Holarrhena floribunda hydro ethanol extract suppresses complete Freund ’s adjuvant-induced arthritis in Sprague-Dawley rats
This study was to evaluate usefulness of the extract for the managem... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 5, 2022 Category: Allergy & Immunology Authors: Stephen Antwi, Daniel Oduro-Mensah, Jerry Asiedu-Larbi, Ebenezer Oduro-Mensah, Olga Quasie, Clara Lewis, David Darko-Obiri, Augustine Ocloo and Laud Kenneth Okine Tags: Research Source Type: research
The effects of two different dietary regimens during exercise on outcome of experimental acute kidney injury
Acute kidney injury (AKI) is a syndrome characterized by rapid loss of excretory function of kidney. Both exercise and some diets have been shown to increase silent information regulator (SIRT1) expression lea... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 2, 2022 Category: Allergy & Immunology Authors: Nazanin Sabet, Zahra Soltani, Mohammad Khaksari and Alireza Raji-Amirhasani Tags: Research Source Type: research
TRIP6 promotes inflammatory damage via the activation of TRAF6 signaling in a murine model of DSS-induced colitis
TRIP6 is a zyxin family member that serves as an adaptor protein to regulate diverse biological processes. In prior reports, TRIP6 was shown to play a role in regulating inflammation. However, its in vivo role... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 4, 2022 Category: Allergy & Immunology Authors: Yun Yang, Xiu-Ming Li, Jing-Ru Wang, Yan Li, Wen-Long Ye, Yi Wang, Yu-Xuan Liu, Zhi-Yong Deng, Wen-Juan Gan and Hua Wu Tags: Short Report Source Type: research
Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis
Studies have shown that ginsenoside R3 (Rg3) plays a protective role in sepsis-induced organ injuries and mitochondrial dysfunction. Long noncoding RNA (lncRNA) taurine-upregulated gene 1 (TUG1) is regarded as... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 20, 2021 Category: Allergy & Immunology Authors: Pan Wu, Xiao Yu, Yue Peng, Qian-Lu Wang, Long-Tian Deng and Wei Xing Tags: Research Source Type: research
