Crtc1 deficiency protects against sepsis-associated acute lung injury through activating akt signaling pathway
Interplay between systemic inflammation and programmed cell death contributes to the pathogenesis of acute lung injury (ALI). cAMP-regulated transcriptional coactivator 1 (CRTC1) has been involved in the norma... (Source: Journal of Inflammation)
Source: Journal of Inflammation - April 22, 2024 Category: Allergy & Immunology Authors: Meng Chen, Jian Lv, Ningning Guo, Tuo Ji, Yu Fang, Zhihua Wang and Xianghu He Tags: Research Source Type: research
Mitochondria protective and anti-apoptotic effects of peripheral benzodiazepine receptor and its ligands on the treatment of asthma in vitro and vivo
Asthma is a prevalent respiratory inflammatory disease. Abnormal apoptosis of bronchial epithelial cells is one of the major factors in the progression of asthma. Peripheral benzodiazepine receptors are highly... (Source: Journal of Inflammation)
Source: Journal of Inflammation - April 19, 2024 Category: Allergy & Immunology Authors: Yurui Liu, Zhengze Zhang, Yuewen He, Ruogen Li, Yuhao Zhang, Hao Liu, Yong Wang and Wuhua Ma Tags: Research Source Type: research
EGFR of platelet regulates macrophage activation and bacterial phagocytosis function
Beyond their crucial role in hemostasis, platelets possess the ability to regulate inflammation and combat infections through various mechanisms. Stringent control of macrophage activation is essential during ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - April 17, 2024 Category: Allergy & Immunology Authors: Shuhua Luo, Riping Xu, Pengyun Xie, Xiaolei Liu, Chunxiu Ling, Yusha Liu, Xuedi Zhang, Zhengyuan Xia, Zhanghui Chen and Jing Tang Tags: Research Source Type: research
Environmental tobacco smoke exposure exaggerates bleomycin-induced collagen overexpression during pulmonary fibrogenesis
Environmental tobacco smoke (ETS) is known to cause lung inflammatory and injurious responses. Smoke exposure is associated with the pathobiology related to lung fibrosis, whereas the mechanism that ETS exposu... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 20, 2024 Category: Allergy & Immunology Authors: Qixin Wang, Chiara Goracci, Isaac Kirubakaran Sundar and Irfan Rahman Tags: Research Source Type: research
Retraction Note: VEGF as a potential molecular target in periodontitis: a meta-analysis and microarray data validation
(Source: Journal of Inflammation)
Source: Journal of Inflammation - March 15, 2024 Category: Allergy & Immunology Authors: Bo Ren, Que Feng, Shan He, Yanfeng Li, Jiadong Fan, Guangquan Chai, Le Liu, Haiyun Liu, Chunhao Yang, Yingdi Wang, Huihui Liu, Huanyue Liu and Yafan Song Tags: Retraction Note Source Type: research
Pediatric sepsis inflammatory blood biomarkers that correlate with clinical variables and severity of illness scores
Sepsis is a dysregulated systemic inflammatory response triggered by infection, resulting in organ dysfunction. A major challenge in clinical pediatrics is to identify sepsis early and then quickly intervene t... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 7, 2024 Category: Allergy & Immunology Authors: Sean Leonard, Hailey Guertin, Natalya Odoardi, Michael R. Miller, Maitray A. Patel, Mark Daley, Gediminas Cepinskas and Douglas D. Fraser Tags: Research Source Type: research
Mucosal-associated invariant T cells in infectious diseases of respiratory system: recent advancements and applications
Mucosal-associated invariant T (MAIT) cells are an atypical subset of T lymphocytes, which have a highly conserved semi-constant αβ chain of T-cell receptor (TCR) and recognize microbe-derived vitamin B metabo... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 28, 2024 Category: Allergy & Immunology Authors: Xue Lin, Ye Wang and Yanqi He Tags: Review Source Type: research
The preventive effects of Lactobacillus casei 03 on Escherichia coli-induced mastitis in vitro and in vivo
Lactobacillus casei possesses many kinds of bioactivities, such as anti-inflammation and anti-oxidant, and has been applied to treating multiple inflammatory diseases. However, its role in mastitis prevention has... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 23, 2024 Category: Allergy & Immunology Authors: Ke Li, Ming Yang, Mengyue Tian, Li Jia, Yinghao Wu, Jinliang Du, Lining Yuan, Lianmin Li and Yuzhong Ma Tags: Research Source Type: research
Tissue-plasminogen activator effects on the phenotype of splenic myeloid cells in acute inflammation
Tissue-plasminogen activator (tPA) is a serine protease well known for its fibrinolytic function. Recent studies indicate that tPA could also modulate inflammation via plasmin generation and/or by receptor mediat... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 14, 2024 Category: Allergy & Immunology Authors: C élia Seillier, Léonie Lesec, Pauline Hélie, Charlotte Marie, Denis Vivien, Fabian Docagne, Brigitte Le Mauff and Olivier Toutirais Tags: Research Source Type: research
Role of meningeal immunity in brain function and protection against pathogens
The brain and spinal cord collectively referred to as the Central Nervous System (CNS) are protected by the blood-brain barrier that limits molecular, microbial and immunological trafficking. However, in the l... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 30, 2024 Category: Allergy & Immunology Authors: Julie Rebejac, Elisa Eme-Scolan and Rejane Rua Tags: Review Source Type: research
Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain
4R is a tobacco cembranoid that binds to and modulates cholinergic receptors and exhibits neuroprotective and anti-inflammatory activity. Given the established function of the cholinergic system in pain and in... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 24, 2024 Category: Allergy & Immunology Authors: Luis G. Rivera-Garc ía, Adela M. Francis-Malavé, Zachary W. Castillo, Calvin D. Uong, Torri D. Wilson, P. A. Ferchmin, Vesna Eterovic, Michael D. Burton and Yarimar Carrasquillo Tags: Research Source Type: research
Interleukin-6-elicited chronic neuroinflammation may decrease survival but is not sufficient to drive disease progression in a mouse model of Leigh syndrome
Mitochondrial diseases (MDs) are genetic disorders characterized by dysfunctions in mitochondria. Clinical data suggest that additional factors, beyond genetics, contribute to the onset and progression of this... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 11, 2024 Category: Allergy & Immunology Authors: Kevin Aguilar, Carla Canal, Gemma Comes, Sandra D íaz-Clavero, Maria Angeles Llanos, Albert Quintana, Elisenda Sanz and Juan Hidalgo Tags: Research Source Type: research
SARS-CoV-2 spike protein accelerates systemic sclerosis by increasing inflammatory cytokines, Th17 cells, and fibrosis
Coronavirus disease 2019 (COVID-19) induces a dysfunctional immune response, inflammation, autoantibody production, and coagulopathy, which are symptoms that bear resemblance to those of autoimmune diseases, i... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 21, 2023 Category: Allergy & Immunology Authors: Ha Yeon Jeong, Jin-Sil Park, Jin Seok Woo, Kun Hee Lee, Jeong Won Choi, Hye Yeon Kang, Hyun Sik Na, Yeon Su Lee, In Gyu Um, Sung-Hwan Park and Mi-La Cho Tags: Research Source Type: research
Retraction Note: Valproic acid attenuates intercellular adhesion molecule-1 and E-selectin through a chemokine ligand 5 dependent mechanism and subarachnoid hemorrhage induced vasospasm in a rat model
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12950-015-0074-3. (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 20, 2023 Category: Allergy & Immunology Authors: Chih-Zen Chang, Shu-Chuan Wu, Chih-Lung Lin and Aij-Lie Kwan Tags: Retraction Note Source Type: research
Lonicera japonica Thunb extract ameliorates lipopolysaccharide-induced acute lung injury associated with luteolin-mediated suppression of NF- κB signaling pathway
Lonicera japonica Thunb (LJT) is a commonly used herbal soup to treat inflammation-related diseases. However, the effect of LJT on ALI is unknown. The present study was aimed at investigating the protective ef... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 19, 2023 Category: Allergy & Immunology Authors: Qinyao Jia, Jing wen, Qi Yang, Shengming Liu, Jianwu Zhang, Tao Wang and Yao Cheng Tags: Research Source Type: research
