Asthmatic condition induced the activity of exosome secretory pathway in rat pulmonary tissues
The recent studies highlighted the critical role of exosomes in the regulation of inflammation. Here, we investigated the dynamic biogenesis of the exosomes in the rat model of asthma. (Source: Journal of Inflammation)
Source: Journal of Inflammation - April 1, 2021 Category: Allergy & Immunology Authors: Asheed Almohammai, Reza Rahbarghazi, Rana Keyhanmanesh, Jafar Rezaie and Mahdi Ahmadi Tags: Research Source Type: research
Interleukin 10 and interleukin 10 receptor in paediatric inflammatory bowel disease: from bench to bedside lesson
The differences between adults and children in inflammatory bowel disease (IBD) phenotype, severity, complications, co-morbidities, and response to the therapy resulted in the extraction of paediatric IBD. It ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 10, 2021 Category: Allergy & Immunology Authors: Paulina Krawiec, Agnieszka Paw łowska-Kamieniak and Elżbieta Pac-Kożuchowska Tags: Review Source Type: research
LncRNA TUG1 regulates the development of ischemia-reperfusion mediated acute kidney injury through miR-494-3p/E-cadherin axis
Acute kidney injury (AKI) results from renal dysfunction caused by various causes, resulting in high mortality. The underlying mechanisms of ischemia-reperfusion (I/R) induced AKI is very complicated and neede... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 4, 2021 Category: Allergy & Immunology Authors: Li Chen, Jun-Ying Xu and Hong-Bao Tan Tags: Research Source Type: research
Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF- κB signal pathway
This study was designed to investigate the role of Pellino1 in lung injury model of sepsis and its anti-inflammation mechanism. (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 25, 2021 Category: Allergy & Immunology Authors: Xiaqing Liu, Zhengfang Lin and Yufeng Xu Tags: Research Source Type: research
Effect of docosahexaenoic acid plus insulin on atherosclerotic human endothelial cells
Atherosclerosis is touted as one of the most critical consequences of diabetes mellitus indicated by local inflammation of endothelial cells. The Effect of Omega 3 fatty acids, mainly docosahexaenoic acid (DHA... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 18, 2021 Category: Allergy & Immunology Authors: Aysan Eslami Abriz, Reza Rahbarghazi, Alireza Nourazarian, Çıgır Biray Avci, Soltan Ali Mahboob, Maryam Rahnema, Atefeh Araghi and Morteza Heidarzadeh Tags: Research Source Type: research
Dendritic cells transduced with TIPE-2 recombinant adenovirus induces T cells suppression
TIPE-2 has been identified as a negative regulator of both innate and adaptive immunity and is involved in several inflammatory diseases. However, the role of immune suppression of dendritic cells (DCs) transd... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 10, 2021 Category: Allergy & Immunology Authors: Shudong Liu, Jie Wang, Wenyan Li, Hui Shi, Changlong Zhou, Ge Tang, Jiangwei Zhang and Zhao Yang Tags: Research Source Type: research
MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1 α/PPAR-γ pathway
Sepsis is a complex syndrome characterized by a dysregulated inflammatory response to systemic infection and leads to shock, multiple organ failure and death especially if not recognized early and treated prom... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 8, 2021 Category: Allergy & Immunology Authors: Wei Wang, Rong-Li Xu, Ping He and Rui Chen Tags: Research Source Type: research
Overexpression of SP1 restores autophagy to alleviate acute renal injury induced by ischemia-reperfusion through the miR-205/PTEN/Akt pathway
Acute kidney injury (AKI) is a major kidney disease with poor clinical outcome. SP1, a well-known transcription factor, plays a critical role in AKI and subsequent kidney repair through the regulation of vario... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 5, 2021 Category: Allergy & Immunology Authors: Chong Huang, Yan Chen, Bin Lai, Yan-Xia Chen, Cheng-Yun Xu and Yuan-Fei Liu Tags: Research Source Type: research
Role of melatonin in the angiogenesis potential; highlights on the cardiovascular disease
Melatonin possesses multi-organ and pleiotropic effects with potency to control angiogenesis at both molecular and cellular levels. To date, many efforts have been made to control and regulate the dynamic of a... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 2, 2021 Category: Allergy & Immunology Authors: Afshin Rahbarghazi, Marefat Siahkouhian, Reza Rahbarghazi, Mahdi Ahmadi, Lotfali Bolboli, Rana Keyhanmanesh, Mahdi Mahdipour and Hadi Rajabi Tags: Review Source Type: research
Lactobacillus fermentum CQPC07 attenuates obesity, inflammation and dyslipidemia by modulating the antioxidant capacity and lipid metabolism in high-fat diet induced obese mice
Obesity is an epidemic disease in the world, the treatment and prevention of obesity methods have gained great attention. Lactobacillus is the main member of probiotics, and the physiological activity of it is... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 2, 2021 Category: Allergy & Immunology Authors: Ya Wu, Xueya Li, Fang Tan, Xianrong Zhou, Jianfei Mu and Xin Zhao Tags: Research Source Type: research
Impact of NF- κB pathway on the intervertebral disc inflammation and degeneration induced by over‐mechanical stretching stress
Intervertebral disk degeneration (IVDD) contributes to low back pain. Increased cell apoptosis and inflammation, decreased extracellular matrix are associated with IVDD. Nuclear factor-kappa B (NF- κB) signalin... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 2, 2021 Category: Allergy & Immunology Authors: Hui Xu, Guobao Qi, Kunpeng Li, Keshi Yang, Dawei Luo and Zhongxu Cai Tags: Research Source Type: research
Anti-inflammatory potential of Quercetin in COVID-19 treatment
SARS-CoV-2 is a betacoronavirus causing severe inflammatory pneumonia, so that excessive inflammation is considered a risk factor for the disease. According to reports, cytokine storm is strongly responsible f... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 28, 2021 Category: Allergy & Immunology Authors: Ali Saeedi-Boroujeni and Mohammad-Reza Mahmoudian-Sani Tags: Hypothesis Source Type: research
Dexamethasone can attenuate the pulmonary inflammatory response via regulation of the lncH19/miR-324-3p cascade
To investigate lncRNAs and their roles in regulating the pulmonary inflammatory response under dexamethasone (Dex) treatment. (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 7, 2021 Category: Allergy & Immunology Authors: Ye Chen, Chao Zhang, Chang-xue Xiao, Xiao-dong Li, Zhi-li Hu, Shou-di He, Xiao-jun Xiao and Feng Xu Tags: Research Source Type: research
Inflammatory M1-like macrophages polarized by NK-4 undergo enhanced phenotypic switching to an anti-inflammatory M2-like phenotype upon co-culture with apoptotic cells
In this study, we examined whether NK-4 exerts a regulatory effect on macrophages, which ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 7, 2021 Category: Allergy & Immunology Authors: Keizo Kohno, Satomi Koya-Miyata, Akira Harashima, Takahiko Tsukuda, Masataka Katakami, Toshio Ariyasu, Shimpei Ushio and Kanso Iwaki Tags: Research Source Type: research
Chronic intermittent hypobaric hypoxia improves markers of iron metabolism in a model of dietary-induced obesity
Obesity, a risk factor for many chronic diseases, is a potential independent risk factor for iron deficiency. Evidence has shown that chronic intermittent hypobaric hypoxia (CIHH) has protective or improved ef... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 7, 2020 Category: Allergy & Immunology Authors: Fang Cui, Jing Guo, Hao-Fei Hu, Yi Zhang and Min Shi Tags: Research Source Type: research
