Systematic review of randomized controlled trials in the treatment of dry eye disease in Sjogren syndrome
Primary Sj ögren’s syndrome is an autoimmune disease characterized by dry eye and dry mouth. We systematically reviewed all the randomized controlled clinical trials published in the last 15 years that included... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 21, 2017 Category: Allergy & Immunology Authors: Kendrick Co Shih, Christie Nicole Lun, Vishal Jhanji, Bernard Yu-Hor Thong and Louis Tong Tags: Review Source Type: research
Hyperoside attenuates dextran sulfate sodium-induced colitis in mice possibly via activation of the Nrf2 signalling pathway
Hyperoside (Hyp) is a flavonoid glycoside compound that has been demonstrated to have anti-inflammatory, anti-apoptotic and antioxidant effects. However, the impact of Hyp on inflammatory bowel disease (IBD) h... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 14, 2017 Category: Allergy & Immunology Authors: Lei Yang, Lei Shen, Yue Li, Yanxia Li, Shijie Yu and Shanshan Wang Tags: Research Source Type: research
Detection of circulating natural antibodies to inflammatory cytokines in type-2 diabetes and clinical significance
Inflammatory cytokines have been demonstrated to be involved in developing insulin resistance and type-2 diabetes (T2D). Natural antibodies in the circulation have protective effects on common diseases in huma... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 6, 2017 Category: Allergy & Immunology Authors: Weiyi Cai, Cailing Qiu, Hongyu Zhang, Xiangyun Chen, Xuan Zhang, Qingyong Meng and Jun Wei Tags: Research Source Type: research
Host responses to concurrent combined injuries in non-human primates
Multi-organ failure (MOF) following trauma remains a significant cause of morbidity and mortality related to a poorly understood abnormal inflammatory response. We characterized the inflammatory response in a ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 2, 2017 Category: Allergy & Immunology Authors: Matthew J. Bradley, Diego A. Vicente, Benjamin A. Bograd, Erin M. Sanders, Crystal L. Leonhardt, Eric A. Elster and Thomas A. Davis Tags: Research Source Type: research
LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro
This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in vi... (Source: Journal of Inflammation)
Source: Journal of Inflammation - October 16, 2017 Category: Allergy & Immunology Authors: Maria Luisa Molina, Julia Guerrero, John A. Cidlowski, H éctor Gatica and Annelise Goecke Tags: Research Source Type: research
Evaluation of a competitive hepcidin ELISA assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients
In this study, a competitive hepcidin ELISA assay was evaluated for its ability to differentiate between iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients, us... (Source: Journal of Inflammation)
Source: Journal of Inflammation - September 18, 2017 Category: Allergy & Immunology Authors: Torbj örn Karlsson Tags: Short Report Source Type: research
Depletion of club cells attenuates bleomycin-induced lung injury and fibrosis in mice
The role of bronchiolar epithelial cells in the pathogenesis of pulmonary fibrosis has not been clarified. We previously demonstrated DNA damage in murine bronchioles in the early stages of bleomycin-induced p... (Source: Journal of Inflammation)
Source: Journal of Inflammation - September 18, 2017 Category: Allergy & Immunology Authors: Tetsuya Yokoyama, Toyoshi Yanagihara, Kunihiro Suzuki, Naoki Hamada, Kazuya Tsubouchi, Saiko Ogata-Suetsugu, Hironori Mikumo, Chika Ikeda-Harada, Takashige Maeyama, Kazuyoshi Kuwano and Yoichi Nakanishi Tags: Research Source Type: research
Leptin independently predicts development of sepsis and its outcome
Sepsis is a life-threatening condition and obesity is related to the clinical outcome. The underlying reasons are incompletely understood, but the adipocyte derived hormones leptin and adiponectin may be invol... (Source: Journal of Inflammation)
Source: Journal of Inflammation - September 11, 2017 Category: Allergy & Immunology Authors: Sofie Jacobsson, Peter Larsson, G öran Johansson, Margareta Norberg, Göran Wadell, Göran Hallmans, Ola Winsö and Stefan Söderberg Tags: Research Source Type: research
Chronic asthma and Mesenchymal stem cells: Hyaluronan and airway remodeling
Previous studies have demonstrated that ovalbumin sensitization promotes chronic asthma phenotype in murine asthma model. Human mesenchymal stem cells (hMSCs) are multipotent cells in vitro that have been show... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 30, 2017 Category: Allergy & Immunology Authors: Benjamin D. Goldstein, Mark E. Lauer, Arnold I. Caplan and Tracey L. Bonfield Tags: Research Source Type: research
Knockdown of miR-155 protects microglia against LPS-induced inflammatory injury via targeting RACK1: a novel research for intracranial infection
Intracranial infection, one of the complications of traumatic brain injury, is usually associated with inflammation. Several microRNAs (miRNAs), including miR-155, have been reported to be critical modulators ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 9, 2017 Category: Allergy & Immunology Authors: Haiyan Yin, Shuwen Song and Xudong Pan Tags: Research Source Type: research
Interleukin-35 on B cell and T cell induction and regulation
Interleukin (IL)-35 is a relatively newly discovered member of IL-12 cytokine family that is unique in that it is a dimer formed by two subunits. The review documents the structure, secretion and signal transd... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 7, 2017 Category: Allergy & Immunology Authors: Ai Huang, Lin Cheng, Miao He, Jun Nie, Jianjun Wang and Ke Jiang Tags: Review Source Type: research
Inflammatory Wnt5A signalling pathways affecting barrier function of human vascular endothelial cells
Wnt5A is a chemokine secreted by inflammatory-activated human macrophages that sustains their inflammatory response in an autocrine manner. High levels of Wnt5A are found in sera of patients with sepsis and se... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 13, 2017 Category: Allergy & Immunology Authors: Tom Skaria and Gabriele Schoedon Source Type: research
Resveratrol protects against ICV collagenase-induced neurobehavioral and biochemical deficits
Indeed, intracerebral hemorrhage (ICH) account for only 15% of all strokes but it is one of the most devastating subtype of stroke associated with behavioral, cognitive and neurological deficits. The primary c... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 9, 2017 Category: Allergy & Immunology Authors: Navdeep Singh, Yashika Bansal, Ranjana Bhandari, Lovish Marwaha, Raghunath Singh, Kanwaljit Chopra and Anurag Kuhad Source Type: research
Tetramethylpyrazine attenuates periorbital allodynia and neuroinflammation in a model of traumatic brain injury
Traumatic brain injury (TBI) is a public health issue. As the major complaint in 51% of TBI patients, chronic pain is an important aspect in TBI treatment. Tetramethylpyrazine (TMP) is an important compound in Li... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 8, 2017 Category: Allergy & Immunology Authors: Zhijing Wang, Qi Wang, Cuijie Wang, Xiuzhen Xu and Hongmei Yu Source Type: research
Regulating STING in health and disease
The presence of cytosolic double-stranded DNA molecules can trigger multiple innate immune signalling pathways which converge on the activation of an ER-resident innate immune adaptor named “STimulator of INte... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 7, 2017 Category: Allergy & Immunology Authors: Yang Li, Heather L. Wilson and Endre Kiss-Toth Source Type: research
