Air pollution induces pyroptosis of human monocytes through activation of inflammasomes and Caspase-3-dependent pathways
According to the World Health Organization (WHO), air pollution is one of the most serious threats for our planet. Despite a growing public awareness of the harmful effects of air pollution on human health, th... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 10, 2023 Category: Allergy & Immunology Authors: Adrianna Ga łuszka-Bulaga, Karolina Tkacz, Kazimierz Węglarczyk, Maciej Siedlar and Jarek Baran Tags: Research Source Type: research
Finding the priority and cluster of inflammatory biomarkers for infectious preterm birth: a systematic review
Infectious preterm birth (PTB) is one of the most important causes of perinatal death. It is difficult to find reliable biomarkers accurate to gestational weeks for infectious PTB prediction clinically. Infect... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 24, 2023 Category: Allergy & Immunology Authors: Jiayi Li, Jianrong Ge, Na Ran, Changwu Zheng, Yumeng Fang, Danna Fang, Qian Yang and Yeling Ma Tags: Review Source Type: research
Inhibition of GSK3 β activity alleviates acute liver failure via suppressing multiple programmed cell death
Acute liver failure (ALF) is one of the most common life-threatening diseases in adults without previous liver disease. Glycogen synthase kinase 3 β (GSK3β) is a serine/threonine protein kinase that is widely d... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 13, 2023 Category: Allergy & Immunology Authors: Danmei Zhang, Chunxia Shi, Qingqi Zhang, Yukun Wang, Jin Guo and Zuojiong Gong Tags: Research Source Type: research
The occurrence and development of radiation-induced lung injury after interstitial brachytherapy and stereotactic radiotherapy in SD rats
To compare the severity of radiation-induced lung injury (RILI) after the right lung of SD rats received interstitial brachytherapy and stereotactic radiotherapy (SBRT). (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 10, 2023 Category: Allergy & Immunology Authors: Zhuo Chen, Bin Wang, Zhouxue Wu, Hua Xiao, Yang Yang, Junying Fan, Yingjiang Gu, Chuan Chen and Jingbo Wu Tags: Research Source Type: research
Stem cell-derived brainstem mouse astrocytes obtain a neurotoxic phenotype in vitro upon neuroinflammation
Astrocytes respond to injury and disease through a process known as reactive astrogliosis, of which inflammatory signaling is one subset. This inflammatory response is heterogeneous with respect to the inducti... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 27, 2023 Category: Allergy & Immunology Authors: Caroline Lindblad, Susanne Neumann, S ólrún Kolbeinsdóttir, Vasilios Zachariadis, Eric P. Thelin, Martin Enge, Sebastian Thams, Lou Brundin and Mikael Svensson Tags: Research Source Type: research
Ischemic stroke-related gene expression profiles across species: a meta-analysis
Stroke patients are often left with permanent disabilities with no regenerative treatment options. Unbiased RNA sequencing studies decoding the transcriptional signature of stroked tissue hold promise to ident... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 19, 2023 Category: Allergy & Immunology Authors: Ruslan Rust Tags: Brief Report Source Type: research
Analysis of AT7519 as a pro-resolution compound in an acetaminophen-induced mouse model of acute inflammation by UPLC-MS/MS
Uncontrolled inflammation contributes to the progression of organ damage in acute conditions, such as acetaminophen-induced acute liver injury (APAP-ALI) and there are limited treatments for this condition. AT... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 8, 2023 Category: Allergy & Immunology Authors: Jennifer A. Cartwright, Joanna P. Simpson, Natalie Z. M. Homer and Adriano G. Rossi Tags: Research Source Type: research
Identification and validation of biomarkers related to Th1 cell infiltration in neuropathic pain
Neuropathic pain (NP) is a widespread chronic pain with a prevalence of 6.9 –10% in the general population, severely affecting patients’ physical and mental health. Accumulating evidence indicated that the immu... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 1, 2023 Category: Allergy & Immunology Authors: Xiangsheng Zhang, Jiurong Cheng, Yingdong Deng, Caiyun Guo, Yu Cao, Suo Wang, Chenxi Zhou, Ziqiang Lin, Simin Tang and Jun Zhou Tags: Research Source Type: research
Dysregulated endothelial cell markers in systemic lupus erythematosus: a systematic review and meta-analysis
To perform a systematic literature review and meta-analysis on endothelial cell (EC) markers that are involved and dysregulated in systemic lupus erythematosus (SLE) in relation to disease activity, as EC dysr... (Source: Journal of Inflammation)
Source: Journal of Inflammation - May 16, 2023 Category: Allergy & Immunology Authors: S. C. Bergkamp, M. J. Wahadat, A. Salah, T. W. Kuijpers, V. Smith, S. W. Tas, J. M. van den Berg, S. Kamphuis and D. Schonenberg-Meinema Tags: Review Source Type: research
Neutrophil extracellular traps in acute coronary syndrome
Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, which can cause heart failure, arrhythmia and even sudden death. It is the major cause of disability and deat... (Source: Journal of Inflammation)
Source: Journal of Inflammation - May 10, 2023 Category: Allergy & Immunology Authors: Yawen Wu, Shilin Wei, Xiangyang Wu, Yongnan Li and Xue Han Tags: Review Source Type: research
PKM2/STAT1-mediated PD-L1 upregulation on neutrophils during sepsis promotes neutrophil organ accumulation by serving an anti-apoptotic role
Delayed neutrophil apoptosis during sepsis may impact neutrophil organ accumulation and tissue immune homeostasis. Elucidating the mechanisms underlying neutrophil apoptosis may help identify potential therape... (Source: Journal of Inflammation)
Source: Journal of Inflammation - May 2, 2023 Category: Allergy & Immunology Authors: Yinjiaozhi Li, Ruoming Tan, Ranran Li, Rui Tian, Zhaojun Liu, Xiaoli Wang, Erzhen Chen, Tingting Pan and Hongping Qu Tags: Research Source Type: research
First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse model of neuroinflammation
The Kynurenine Pathway (KP) of tryptophan degradation and glutamate toxicity is implicated in several neurological disorders, including depression. The therapeutic potential of mesenchymal stromal cells (MSC),... (Source: Journal of Inflammation)
Source: Journal of Inflammation - May 1, 2023 Category: Allergy & Immunology Authors: Fyyaz Siddiqui, Denis Gallagher, Hannah Shuster-Hyman, Lianet Lopez, Andr ée Gauthier-Fisher and Clifford L Librach Tags: Research Source Type: research
Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study
Osteoarthritis (OA) is a common joint disease and is the main cause of physical disability in the elderly. Currently, there is no adequate therapeutic strategy to reverse the progression of OA. Many natural pl... (Source: Journal of Inflammation)
Source: Journal of Inflammation - April 13, 2023 Category: Allergy & Immunology Authors: Qing Ding, Ruizhuo Zhang, Gaohong Sheng, Tianqi Wang, Shaoze Jing, Tian Ma, Shanxi Wang, Hongqi Zhao, Hua Wu and Wenkai Li Tags: Research Source Type: research
Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury
Acute lung injury (ALI) is a life-threatening condition that fundamentally results from inflammation and edema in the lung. There are no effective treatments available for clinical use. Previously, we found th... (Source: Journal of Inflammation)
Source: Journal of Inflammation - April 6, 2023 Category: Allergy & Immunology Authors: Yeomyeong Kim, Cho-Rong Bae, Dongyeop Kim, Hyejeong Kim, Sunghye Lee, Haiying Zhang, Minyoung Noh, Young-Myeong Kim, Naoki Mochizuki and Young-Guen Kwon Tags: Research Source Type: research
Network analyses reveal new insights into the effect of multicomponent Tr14 compared to single-component diclofenac in an acute inflammation model
Modifying the acute inflammatory response has wide clinical benefits. Current options include non-steroidal anti-inflammatory drugs (NSAIDs) and therapies that may resolve inflammation. Acute inflammation invo... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 27, 2023 Category: Allergy & Immunology Authors: Matti Hoch, Suchi Smita, Konstantin Cesnulevicius, Myron Schultz, David Lescheid, Olaf Wolkenhauer and Shailendra Gupta Tags: Research Source Type: research
