Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress
It is well considered that reactive oxygen species (ROS) plays a prominent causative role in the development of allergic rhinitis (AR), and eosinophils cells as important allergic inflammatory cells contribute... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 13, 2017 Category: Allergy & Immunology Authors: Shaoqing Yu, Chuanliang Zhao, Na Che, Lin Jing and Rongming Ge Source Type: research
Cardiovascular diseases-related GNB3 C825T polymorphism has a significant sex-specific effect on serum soluble E-selectin levels
The C825T polymorphism (rs5443) of the Guanine Nucleotide-Binding protein subunit β3 (GNB3) gene has been associated with obesity, essential hypertension, atherosclerosis, coronary diseases, and cerebrovascular e... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 9, 2016 Category: Allergy & Immunology Authors: Koko è Mélinda Gbadoe, Nazha Berdouzi, Alex-Ander Aldasoro Aguiñano, Ndeye Coumba Ndiaye and Sophie Visvikis-Siest Source Type: research
Increased adipose tissue expression of TLR8 in obese individuals with or without type-2 diabetes: significance in metabolic inflammation
The innate immune Toll-like receptors (TLRs) 2/4 are important players in chronic low-grade inflammation called metabolic inflammation in obesity and type-2 diabetes (T2D). While TLR2/4 expression changes asso... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 8, 2016 Category: Allergy & Immunology Authors: Rasheed Ahmad, Shihab Kochumon, Reeby Thomas, Valerie Atizado and Sardar Sindhu Source Type: research
Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuries
Ethyl pyruvate (EP) is a simple derivative of pyruvic acid, which is an important endogenous metabolite that can scavenge reactive oxygen species (ROS). Treatment with EP is able to ameliorate systemic inflamm... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 3, 2016 Category: Allergy & Immunology Authors: Runkuan Yang, Shengtao Zhu and Tor Inge Tonnessen Source Type: research
Riboflavin along with antibiotics balances reactive oxygen species and inflammatory cytokines and controls Staphylococcus aureus infection by boosting murine macrophage function and regulates inflammation
Macrophages serve as intracellular reservoirs of S. aureus. Recent in vitro studies have confirmed high level resistance by S. aureus to macrophage mediated killing and the intracellular persistence of Staphyloco... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 28, 2016 Category: Allergy & Immunology Authors: Somrita Dey and Biswadev Bishayi Source Type: research
Prognostic value of inflammation in prostate cancer progression and response to therapeutic: a critical review
Prostate is an immune-competent organ normally populated by inflammatory cells. Prostatic inflammation origin can be multi-factorial and there are some emerging evidences on its possible role as a factor invol... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 25, 2016 Category: Allergy & Immunology Authors: Alessandro Sciarra, Alessandro Gentilucci, Stefano Salciccia, Federico Pierella, Flavio Del Bianco, Vincenzo Gentile, Ida Silvestri and Susanna Cattarino Source Type: research
Effects of metformin on blood and urine pro-inflammatory mediators in patients with type 2 diabetes
Metformin has been used for the treatment of type 2 diabetes by suppressing hepatic gluconeogenesis. It has been shown that the subclinical inflammatory responses play important roles in the pathogenesis of ty... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 24, 2016 Category: Allergy & Immunology Authors: Wei Chen, Xiaojie Liu and Shandong Ye Source Type: research
Electric stimulation of the vagus nerve reduced mouse neuroinflammation induced by lipopolysaccharide
Neuroinflammation (NI) is a key feature in the pathogenesis and progression of infectious and non-infectious neuropathologies, and its amelioration usually improves the patient outcome. Peripheral inflammation... (Source: Journal of Inflammation)
Source: Journal of Inflammation - October 29, 2016 Category: Allergy & Immunology Authors: G. Meneses, M. Bautista, A. Florentino, G. D íaz, G. Acero, H. Besedovsky, D. Meneses, A. Fleury, A. Del Rey, G. Gevorkian, G. Fragoso and E. Sciutto Source Type: research
Circulating chemokine ligand levels before and after successful kidney transplantation
Chemokine ligands (CCLs) play a pivotal role in tissue injury before and after kidney transplantation. Meanwhile, transplantation improves patient ’s survival and diminishes morbidity. It is hypothesized, then,... (Source: Journal of Inflammation)
Source: Journal of Inflammation - October 26, 2016 Category: Allergy & Immunology Authors: Hamdi Elmoselhi, Holly Mansell, Mahmoud Soliman and Ahmed Shoker Source Type: research
Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages
Osteoarthritis (OA) is described by an imbalance between anabolic and catabolic processes in the affected joint. This dysregulation of metabolism affects not only chondrocytes within cartilage tissue but also ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - September 13, 2016 Category: Allergy & Immunology Authors: Christoph Bauer, Eugenia Niculescu-Morzsa, Vivek Jeyakumar, Daniela Kern, Stephan S. Sp äth and Stefan Nehrer Source Type: research
Circulating adipokine levels and prognostic value in septic patients
Adipokines have a wide range of effects and are linked to sepsis and septic shock. The aim of the present study was to describe the changes in adipokine levels in septic patients in relation to patients ’ prese... (Source: Journal of Inflammation)
Source: Journal of Inflammation - September 6, 2016 Category: Allergy & Immunology Authors: Andreas Hillenbrand, Pengfei Xu, Shaoxia Zhou, Annette Blatz, Manfred Weiss, Sebastian Hafner, Doris Henne-Bruns and Uwe Knippschild Source Type: research
Acidification changes affect the inflammasome in human nucleus pulposus cells
Interleukin (IL)-1 β is involved in the pathology of intervertebral disc degeneration. Under normal conditions, IL-1β is present in cells in an inactive form (pro-IL-1β). However, under pathological conditions,... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 24, 2016 Category: Allergy & Immunology Authors: Frank J. Brand, Mahtab Forouzandeh, Harmanpreet Kaur, Francesco Travascio and Juan Pablo de Rivero Vaccari Source Type: research
Monocyte chemoattractant protein-1 is not required for liver regeneration after partial hepatectomy
Liver regeneration following 70 % partial hepatectomy (PH) requires the coordinated expression of soluble mediators produced by macrophages. Monocyte chemoattractant protein-1 (MCP-1) is a potent stimulus of m... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 22, 2016 Category: Allergy & Immunology Authors: Stephanie L. Wyler, Shawna L. D ’Ingillo, Cheri L. Lamb and Kristen A. Mitchell Source Type: research
Peroxisome proliferator-activated receptor (PPAR) α and δ activators induce ICAM-1 expression in quiescent non stimulated endothelial cells
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that are implicated in the regulation of lipid and glucose homeostasis. PPAR agonists have been shown to control i... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 20, 2016 Category: Allergy & Immunology Authors: Julia Naidenow, Igor Hrgovic, Monika Doll, Tsige Hailemariam-Jahn, Victoria Lang, Johannes Kleemann, Stefan Kippenberger, Roland Kaufmann, Nadja Z öller and Markus Meissner Source Type: research
Nasal inflammation and its response to local glucocorticoid regular treatment in patients with persistent non-allergic rhinitis: a pilot study
The pathogenesis of non-allergic rhinitis (NAR) is still largely unknown. Furthermore, it is unclear whether there is a correlation between the effect of nasal glucocorticoids on nasal inflammation and on nasa... (Source: Journal of Inflammation)
Source: Journal of Inflammation - August 4, 2016 Category: Allergy & Immunology Authors: Donatella Poletti, Valeria Iannini, Paolo Casolari, Marco Contoli, Alberto Papi, Paul Kirkham, Trevor T. Hansel, Kian Fan Chung, Peter J. Barnes, Antonio Pastore, Stefano Pelucchi, Ian M. Adcock and Gaetano Caramori Source Type: research
