Red cell distribution width (RDW) as a biomarker for respiratory failure in a pediatric ICU
The red cell distribution width (RDW) is a widely available, inexpensive, and highly reproducible test that reflects the range of the red cell sizes. Any process that releases reticulocytes in the circulation ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 7, 2017 Category: Allergy & Immunology Authors: Tom Schepens, Jozef J. De Dooy, Walter Verbrugghe and Philippe G. Jorens Source Type: research
WIF1 prevents Wnt5A mediated LIMK/CFL phosphorylation and adherens junction disruption in human vascular endothelial cells
Wnt5A is released by activated macrophages and elevated levels have been detected in sepsis patients with severe systemic inflammation. However, the signalling and functional effects of Wnt5A in the vascular e... (Source: Journal of Inflammation)
Source: Journal of Inflammation - May 19, 2017 Category: Allergy & Immunology Authors: Tom Skaria, Esther Bachli and Gabriele Schoedon Source Type: research
Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle
Obesity-induced inflammation causes skeletal muscle atrophy accompanied by disruption of oxidative metabolism and is implicated in metabolic complications such as insulin resistance and type 2 diabetes. We pre... (Source: Journal of Inflammation)
Source: Journal of Inflammation - May 11, 2017 Category: Allergy & Immunology Authors: Ngoc Hoan Le, Chu-Sook Kim, Thai Hien Tu, Byung-Sam Kim, Taesun Park, Jung Han Yoon Park, Tsuyoshi Goto, Teruo Kawada, Tae Youl Ha and Rina Yu Source Type: research
Successful reduction of inflammatory responses and arachidonic acid –cyclooxygenase 2 pathway in human pulmonary artery endothelial cells by silencing adipocyte fatty acid-binding protein
Adipocyte fatty acid-binding protein, also known as aP2 or fatty acid-binding protein 4 (FABP4), plays an important role in inflammatory and metabolic responses in adipocytes and macrophages. Recent work has d... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 20, 2017 Category: Allergy & Immunology Authors: Qian Wang, Guanglin Shi, Ying Teng, Xia Li, Jin Xie, Qin Shen, Caixin Zhang, Songshi Ni and Zhiyuan Tang Source Type: research
Ulinastatin ameliorates tissue damage of severe acute pancreatitis through modulating regulatory T cells
Ulinastatin or urinary trypsin inhibitor (UTI) has been shown to ameliorate the inflammatory response induced by experimental severe acute pancreatitis (SAP) and hence reduce the mortality, however the mechani... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 20, 2017 Category: Allergy & Immunology Authors: Yu Pan, Haizong Fang, Fengchun Lu, Minggui Pan, Fei Chen, Ping Xiong, Yi Yao and Heguang Huang Source Type: research
Successful reduction of inflammatory responses and arachidonic acid –cyclooxygenase 2 pathway in human pulmonary artery endothelial cells by silencing adipocyte fatty acid-binding protein
Adipocyte fatty acid-binding protein, also known as aP2 or fatty acid-binding protein 4 (FABP4), plays an important role in inflammatory and metabolic responses in adipocytes and macrophages. Recent work has d... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 20, 2017 Category: Allergy & Immunology Authors: Qian Wang, Guanglin Shi, Ying Teng, Xia Li, Jin Xie, Qin Shen, Caixin Zhang, Songshi Ni and Zhiyuan Tang Source Type: research
Ulinastatin ameliorates tissue damage of severe acute pancreatitis through modulating regulatory T cells
Ulinastatin or urinary trypsin inhibitor (UTI) has been shown to ameliorate the inflammatory response induced by experimental severe acute pancreatitis (SAP) and hence reduce the mortality, however the mechani... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 20, 2017 Category: Allergy & Immunology Authors: Yu Pan, Haizong Fang, Fengchun Lu, Minggui Pan, Fei Chen, Ping Xiong, Yi Yao and Heguang Huang Source Type: research
Overexpression of aquaporin 4 in articular chondrocytes exacerbates the severity of adjuvant-induced arthritis in rats: an in vivo and in vitro study
This study was aimed to investigate the expression of a... (Source: Journal of Inflammation)
Source: Journal of Inflammation - March 1, 2017 Category: Allergy & Immunology Authors: Li Cai, Chao Lei, Rong Li, Wei-na Chen, Cheng-mu Hu, Xiao-yu Chen and Chun-mei Li Source Type: research
Influence of vaginal lactoferrin administration on amniotic fluid cytokines and its role against inflammatory complications of pregnancy
An altered amniotic cytokine profile has been reported in inflammatory pregnancy complications with a leading role for IL-6, a marker of the foetal systemic inflammatory response. Up to this date there is no e... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 15, 2017 Category: Allergy & Immunology Authors: Martina Maritati, Manola Comar, Nunzia Zanotta, Silva Seraceni, Alessandro Trentini, Fabrizio Corazza, Fortunato Vesce and Carlo Contini Source Type: research
Higher phagocytic activity of thioglycollate-elicited peritoneal macrophages is related to metabolic status of the cells
Peritoneal macrophages are widely used in immunological studies. The cells can be collected under non-elicited (resident) or elicited (e.g., with Brewer thioglycollate broth injection) conditions, and their ph... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 10, 2017 Category: Allergy & Immunology Authors: Sofia Pavlou, Luxi Wang, Heping Xu and Mei Chen Source Type: research
Ezetimibe reduces cholesterol content and NF-kappaB activation in liver but not in intestinal tissue in guinea pigs
Statins (HMG CoA reductase inhibitors), in addition to reducing circulating cholesterol and incidence of coronary heart disease, also have pleiotropic, anti-inflammatory effects. Patients with chronic liver di... (Source: Journal of Inflammation)
Source: Journal of Inflammation - February 2, 2017 Category: Allergy & Immunology Authors: Peter Fraunberger, Elisabeth Gr öne, Hermann-Josef Gröne, Heinz Drexel and Autar K. Walli Source Type: research
Effects of corticosteroid plus long-acting beta2-agonist on the expression of PD-L1 in double-stranded RNA-induced lung inflammation in mice
Airway viral infections cause the exacerbations of asthma and chronic obstructive pulmonary disease. PD-L1, also known as B7-H1, is an immune-checkpoint molecule that plays a role in an escape mechanism of vir... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 17, 2017 Category: Allergy & Immunology Authors: Saaka Hamano, Koichiro Matsumoto, Ken Tonai, Satoru Fukuyama, Keiko Kan-o, Nanae Seki, Hiromasa Inoue and Yoichi Nakanishi Source Type: research
