Corpus cavernosum smooth muscle cell dysfunction and phenotype transformation are related to erectile dysfunction in prostatitis rats with chronic prostatitis/chronic pelvic pain syndrome
This study was... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 6, 2020 Category: Allergy & Immunology Authors: Guang-chun Wang, Tian-run Huang, Yang-yang Hu, Ke-yi Wang, Heng Shi, Lei Yin and Bo Peng Tags: Research Source Type: research
Effects of long non-coding RNA Gm14461 on pain transmission in trigeminal neuralgia
This study aims to investigate the role of long non-coding RNA Gm14461 in regulating pain transmission in trigeminal neuralgia (TN). The mouse TN model was produced by chronic constriction injury of the infrao... (Source: Journal of Inflammation)
Source: Journal of Inflammation - January 3, 2020 Category: Allergy & Immunology Authors: Mu Xu, Yi Yan, Mengye Zhu, Zhijian Wang, Xuexue Zhang and Daying Zhang Tags: Research Source Type: research
Nerve growth factor inhibits TLR3-induced inflammatory cascades in human corneal epithelial cells
In herpes simplex epithelial keratitis, excessive TLR3-induced cellular responses after virus infection evoke inflammatory cascades that might be destructive to the host cornea. Nerve growth factor (NGF), a pl... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 26, 2019 Category: Allergy & Immunology Authors: Huiyu Chen, Jing Zhang, Yiqin Dai and Jianjiang Xu Tags: Research Source Type: research
Exploring the association of IL-10 polymorphisms in Behcet ’s disease: a systematic review and meta-analysis
This study aimed to perform a meta-analysis of eligible studies ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 23, 2019 Category: Allergy & Immunology Authors: Elham Shahriyari, Leila Vahedi, Nasrin Roshanipour, Mohammad Asghari Jafarabadi, Amin Khamaneh and Maryam Ghaffari Laleh Tags: Research Source Type: research
The double edge of anti-CD40 siRNA therapy: It increases renal microcapillar density but favours the generation of an inflammatory milieu in the kidneys of ApoE −/− mice
Chronic kidney disease (CKD) is associated with endothelial dysfunctions thus prompting links between microcirculation (MC), inflammation and major cardiovascular risk factors. (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 16, 2019 Category: Allergy & Immunology Authors: Miguel Hueso, Angela Casas, Adrian Mall én, Laura de Ramón, Nuria Bolaños, Cristian Varela, Josep M. Cruzado, Joan Torras and Estanislao Navarro Tags: Research Source Type: research
Nrdp1 increases neuron apoptosis via downregulation of Bruce following intracerebral haemorrhage
Neuregulin receptor degradation protein-1 (Nrdp1) is an E3 ubiquitin ligase that plays an important role in regulating cell growth, apoptosis and oxidative stress. However, the data regarding its expression an... (Source: Journal of Inflammation)
Source: Journal of Inflammation - December 9, 2019 Category: Allergy & Immunology Authors: Changlong Zhou, Qingjun Liu, Wang Zhao, Ling Yang, Zhongyan Huang and Zhao Yang Tags: Research Source Type: research
LncRNA H19 induced by helicobacter pylori infection promotes gastric cancer cell growth via enhancing NF- κB-induced inflammation
The aim of this study was to investigate the role of long non-coding RNA (lncRNA) H19 in gastric cancer (GC) with Helicobacter pylori (H. pylori). (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 26, 2019 Category: Allergy & Immunology Authors: Yifeng Zhang, Jin Yan, Chao Li, Xiaoyong Wang, Yu Dong, Xiaoran Shen and Ximei Zhang Tags: Research Source Type: research
Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus
Lupus nephritis (LN) affects up to 80% of juvenile-onset systemic lupus erythematosus patients. Mesangial cells (MCs) comprise a third of the glomerular cells and are key contributors to fibrotic changes withi... (Source: Journal of Inflammation)
Source: Journal of Inflammation - November 14, 2019 Category: Allergy & Immunology Authors: Rachael D. Wright, Paraskevi Dimou, Sarah J. Northey and Michael W. Beresford Tags: Research Source Type: research
Liraglutide exhibits anti-inflammatory activity through the activation of the PKA/CREB pathway
Qihong Que and colleagues found that liraglutide exhibited anti-inflammatory activity through the activation of the PKA/CREB pathway in an OA rat model. We believe there was a flaw in this research. In their f... (Source: Journal of Inflammation)
Source: Journal of Inflammation - October 11, 2019 Category: Allergy & Immunology Authors: Li Wang, Linjie Feng and Jingyu Zhang Tags: Commentary Source Type: research
Structural and functional abnormalities of penile cavernous endothelial cells result in erectile dysfunction at experimental autoimmune prostatitis rat
There is growing recognition of the association of CP/CPPS accompany with ED. However, the specific mechanism of action remains unclear. The aim of this study was to investigate structural and functional abnor... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 25, 2019 Category: Allergy & Immunology Authors: Tianrun Huang, Guangchun Wang, Yangyang Hu, Heng Shi, Keyi Wang, Lei Yin and Bo Peng Tags: Research Source Type: research
IL-35 alleviates inflammation progression in a rat model of diabetic neuropathic pain via inhibition of JNK signaling
Emerging evidence has demonstrated that inflammation is involved in the occurrence and development of diabetic neuropathic pain (DNP). The anti-inflammatory property of interleukin (IL)-35 makes it a promising... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 23, 2019 Category: Allergy & Immunology Authors: Yinghai Jiang, Jing Wang, Haiqin Li and Lingjie Xia Tags: Research Source Type: research
The in vitro Mycobacterium bovis BCG Moreau infection of human monocytes that induces Caspase-1 expression, release and dependent cell death is mostly reliant upon cell integrity
Caused by Mycobacterium tuberculosis, tuberculosis (TB) is an extremely contagious disease predominantly affecting the lungs. TB is found worldwide and has a major impact on public health safety primarily due to ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 15, 2019 Category: Allergy & Immunology Authors: Paulo R. Z. Antas, Carlos G. G. Ponte, Matheus R. Almeida, Lawrence H. P. Albuquerque, Periela S. Sousa-Vasconcelos, Tha íze Pedro, Natália L. S. Gomes, Otacílio C. Moreira, Fernanda C. Silva, Luíz R. R. Castello-Branco and Rosa T. Pinho Tags: Research Source Type: research
Deficiency of fibroblast growth factor 21 aggravates obesity-induced atrophic responses in skeletal muscle
Obesity-induced skeletal muscle inflammation is a major contributor of skeletal muscle loss/atrophy and is implicated in metabolic complications such as insulin resistance. Fibroblast growth factor 21 (FGF21) ... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 4, 2019 Category: Allergy & Immunology Authors: Chu-Sook Kim, Yeonsoo Joe, Hye-Seon Choi, Sung Hoon Back, Jeong Woo Park, Hun Taeg Chung, Eun Roh, Min-Seon Kim, Tae Youl Ha and Rina Yu Tags: Research Source Type: research
Hypertonic solution-induced preconditioning reduces inflammation and mortality rate
Dysregulated inflammatory response is common cause of organ damage in critical care patients. Preconditioning/tolerance is a strategy to prevent exacerbated inflammation. The aim of this study is to analyze hy... (Source: Journal of Inflammation)
Source: Journal of Inflammation - July 3, 2019 Category: Allergy & Immunology Authors: Rosangela Nascimento Pimentel, Ricardo Costa Petroni, Hermes Vieira Barbeiro, Denise Frediani Barbeiro, Mariana Macedo Andrade, Suely Kumini Ariga and Francisco Garcia Soriano Tags: Research Source Type: research
“In sickness and in health” – how neutrophil extracellular trap (NET) works in infections, selected diseases and pregnancy
The discovery of the NET network (neutrophil extracellular trap) has revolutionized the perception of defense mechanisms used by neutrophils in infections and non-infectious states, as this mechanism proves th... (Source: Journal of Inflammation)
Source: Journal of Inflammation - June 28, 2019 Category: Allergy & Immunology Authors: Paulina Nied źwiedzka-Rystwej, Weronika Repka, Beata Tokarz-Deptuła and Wiesław Deptuła Tags: Review Source Type: research
