Journal of Bone and Mineral Metabolism This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Quantitative investigation of the effect of surgically induced hypoparathyroidism on cataract development
ConclusionThe clarity of the crystalline lens may decrease in surgically induced hypoparathyroidism patients depending on the disease duration and PTH levels. Additionally, this study detected an increased frequency of blue-dot-like cataract in the patient group, which may be due to the effect of hypoparathyroidism. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - July 27, 2021 Category: Orthopaedics Source Type: research

Assessment of bone repair in animal models with suppressed osteoclast function by pretreatment of bisphosphonates
(Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - July 21, 2021 Category: Orthopaedics Source Type: research

Lower trabecular bone score is associated with an increased incidence of localized femoral periosteal thickening
ConclusionsThe TBS was lower in glucocorticoid-treated Japanese women with autoimmune diseases with LPT than in those without LPT, and deteriorated trabecular microarchitecture influenced by longer use of BP and glucocorticoid might be associated with the development of LPT. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - July 20, 2021 Category: Orthopaedics Source Type: research

Clinical performance of a novel chemiluminescent enzyme immunoassay for FGF23
ConclusionThe novel FGF23 assay tested in this study is useful for the differential diagnosis of hypophosphatemic rickets/osteomalacia in a clinical setting. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - July 13, 2021 Category: Orthopaedics Source Type: research

Recent advances in the epigenetics of bone metabolism
AbstractOsteoporosis is a common form of metabolic bone disease that is costly to treat and is primarily diagnosed on the basis of bone mineral density. As the influences of genetic lesions and environmental factors are increasingly studied in the pathological development of osteoporosis, regulated epigenetics are emerging as the important pathogenesis mechanisms in osteoporosis. Recently, osteoporosis genome-wide association studies and multi-omics technologies have revealed that susceptibility loci and the misregulation of epigenetic modifiers are key factors in osteoporosis. Over the past decade, extensive studies have ...
Source: Journal of Bone and Mineral Metabolism - July 11, 2021 Category: Orthopaedics Source Type: research

Anti-RANKL monoclonal antibody and bortezomib prevent mechanical unloading-induced bone loss
ConclusionsWe demonstrated for the first time that anti-RANKL antibody and Bzb had a positive effect on preventing mechanical unloading-induced bone loss. This finding puts forward the potential use of anti-RANKL and Bzb on bone loss therapies or prophylaxis of astronauts in spaceflight. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - July 1, 2021 Category: Orthopaedics Source Type: research

Elevated red blood cell distribution width is associated with poor outcome in osteoporotic vertebral fracture
ConclusionElevated RDW was associated with the poor clinical outcomes of conservative treatment of an OVF, independent of osteoporosis or severity of the OVF. RDW provides prognostic information for risk stratification as a senescence biomarker. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - July 1, 2021 Category: Orthopaedics Source Type: research

Adjuvant endocrine therapy effects on bone mineral density and microstructure in women with breast cancer
ConclusionPostmenopausal women who received AIs for early breast cancer experienced significant trabecular and cortical bone deterioration and a decrease in estimated bone strength within only 1  year. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 30, 2021 Category: Orthopaedics Source Type: research

6-Shogaol promotes bone resorption and accelerates orthodontic tooth movement through the JNK-NFATc1 signaling axis
In conclusion, our results suggest that 6-shogoal accelerates tooth movement by inducing osteopenia by a mechanism similar to surgically induced bone injury. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 30, 2021 Category: Orthopaedics Source Type: research

Simvastatin reverses the harmful effects of high fat diet on titanium rod osseointegration in ovariectomized rats
ConclusionOur findings revealed that HFD may have an adverse effect on osseointegration in osteoporotic conditions, and the harmful effect of HFD on osseointegration could be reversed by SIM. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 29, 2021 Category: Orthopaedics Source Type: research

Selenium-modified calcium phosphate cement can accelerate bone regeneration of osteoporotic bone defect
ConclusionOur current study demonstrated that Se-CPC is a scheme for rapid repair of femoral condylar defects, and these effects may be achieved by inhibiting local oxidative stress and through OPG/RANKL signaling pathway. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 29, 2021 Category: Orthopaedics Source Type: research

Epidemiology of glucocorticoid-induced osteoporosis and management of associated fracture risk in Japan
ConclusionIn spite of publication of guidelines for GIOP management, there is an important treatment gap in their application in everyday practice. For this reason, public health measures to increase physician awareness of GIOP are needed. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 14, 2021 Category: Orthopaedics Source Type: research

Effect of serum 25-hydroxyvitamin D concentrations on skeletal mineralization in black and white women
ConclusionsOur study indicated: (1) vitamin D deficiency is common, but bone mineralization is not impaired in black women, and (2) there are no significant correlations between serum 25(OH)D levels and bone mineralization indices, suggesting that vitamin D deficiency may not be an independent factor contributing to bone mineralization defects and osteomalacia. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 14, 2021 Category: Orthopaedics Source Type: research

Comparison of novel DXA system, Shimazu SONIALVISION G4, with GE-Lunar PRODIGY
ConclusionsAlthough BMD values by SONIALVISION G4 were close to those by PRODIGY, follow-up studies should be performed using the same device because of the small difference between devices. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 11, 2021 Category: Orthopaedics Source Type: research

Vitamin D level and fractures in children and adolescents: a systematic review and meta-analysis
ConclusionThere is no relationship between vitamin D level and the risk of bone fractures in children and adolescents. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - June 11, 2021 Category: Orthopaedics Source Type: research