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The effect of forearm rotation on the bone mineral density measurements of the distal radius
ConclusionSubtle rotational changes affected the BMD measurement of each region. The results showed the importance of forearm positioning when measuring the distal radius BMD. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - December 6, 2023 Category: Orthopaedics Source Type: research

Tea consumption and risk of bone health: an updated systematic review and meta-analysis
ConclusionThere is an association between tea consumption and a reduced risk of fractures, osteoporosis, hip, femur, and lumbar, as well as increased BMD. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - December 6, 2023 Category: Orthopaedics Source Type: research

miR-92a-3p-inspired shRNA exhibits pro-chondrogenic and chondrocyte protective effects in osteoarthritis treatment through targeting SMAD6/7
ConclusionsmiR-92a-3p and shRNA-92a-3p exhibit therapeutic effects in treating OA by targeting SMAD6 and SMAD7, thereby enhancing TGF- β signaling. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - December 6, 2023 Category: Orthopaedics Source Type: research

Journal of Bone and Mineral Metabolism Best Paper Award 2023
(Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - November 27, 2023 Category: Orthopaedics Source Type: research

List of reviewers 2023
(Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - November 22, 2023 Category: Orthopaedics Source Type: research

Sirtuin 6 ameliorates arthritis through modulating cyclic AMP-responsive element binding protein/CCN1/cyclooxygenase 2 pathway in osteoblasts
ConclusionOur study indicated that the benefits of SIRT6 to inflammatory arthritis and bone resorption are at least partially derived from its modulation of CREB/CCN1/COX2 pathway in osteoblasts. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - October 29, 2023 Category: Orthopaedics Source Type: research

A diagnostic approach integrated multimodal radiomics with machine learning models based on lumbar spine CT and X-ray for osteoporosis
ConclusionThe combined model displayed outstanding ability in diagnosing osteoporosis, providing a safe and efficient method for clinical decision-making. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - October 28, 2023 Category: Orthopaedics Source Type: research

Reliability of early stage symptoms/clinical findings of osteonecrosis of the jaw: Japanese Osteoporosis Intervention Trial-05 (JOINT-05)
ConclusionTooth mobility accompanied by clinical periodontal symptoms may be a useful early sign of stage 0 ONJ. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - October 28, 2023 Category: Orthopaedics Source Type: research

Frequency and determinants of serum calcium monitoring during eldecalcitol therapy in patients with osteoporosis
ConclusionOur findings suggest that serum calcium monitoring is not given adequate attention during ELD therapy in routine clinical practice. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - October 28, 2023 Category: Orthopaedics Source Type: research

Development of Cu application using dual-energy computed tomography for detecting medication-related osteonecrosis of the jaw
ConclusionDECT-Cu application demonstrated better diagnostic performance in detecting MRONJ compared with single-energy CT or DECT-VNCa. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - October 28, 2023 Category: Orthopaedics Source Type: research

Effects of bisphosphonates and treadmill exercise on bone and kidney in adenine-induced chronic kidney disease rats
ConclusionThe combination of ALN and treadmill exercise is effective in improving BMD, the microstructure of trabecular and cortical bone, and bone strength, without compromising renal function in adenine-induced CKD model rats. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - October 28, 2023 Category: Orthopaedics Source Type: research

JSBMR and JBMM mourn the death of Dr. Fujio Suzuki
(Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - September 12, 2023 Category: Orthopaedics Source Type: research

Deterioration of apatite orientation in the cholecystokinin B receptor gene (Cckbr)-deficient mouse femurs
ConclusionLesions in Cckbr-deficient mice occurred earlier in apatite orientation than in bone mass. Hence, bone apatite orientation may be a promising method for detecting hypochlorhydria-induced osteoporosis caused by PPI treatment and warrants urgent clinical applications. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - September 7, 2023 Category: Orthopaedics Source Type: research

Zoledronate treatment exerts sex-independent effects on bone and dental physicochemical properties in mice jaw necrosis
ConclusionDespite sex-dependent differences in bone biomechanics and density, osteonecrosis was established with no sex influence. No synergistic association between sex and treatment factors was observed in this study. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - September 7, 2023 Category: Orthopaedics Source Type: research

Adherence to the dietary approaches to stop hypertension and bone health in the Chinese elderly
ConclusionAdherence to the DASH dietary pattern was associated with better bone health in Chinese elderly adults. (Source: Journal of Bone and Mineral Metabolism)
Source: Journal of Bone and Mineral Metabolism - September 5, 2023 Category: Orthopaedics Source Type: research