Deterioration of apatite orientation in the cholecystokinin B receptor gene (Cckbr)-deficient mouse femurs

ConclusionLesions in Cckbr-deficient mice occurred earlier in apatite orientation than in bone mass. Hence, bone apatite orientation may be a promising method for detecting hypochlorhydria-induced osteoporosis caused by PPI treatment and warrants urgent clinical applications.
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research