PPIs Cut Upper GI Bleeds From Anticoagulants
(MedPage Today) -- Bleeding risk was highest with rivaroxaban, lowest with apixaban (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 9, 2018 Category: Cardiology Source Type: news

Risk-Score Insights on How DOACs Vary in Upper GI Bleed Risk Risk-Score Insights on How DOACs Vary in Upper GI Bleed Risk
Adding a proton-pump inhibitor to oral anticoagulation can defend against gastrointestinal bleeding, but with varying success, depending on which oral anticoagulant, especially in high-risk patients.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 7, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Be warned: Older adults who take PPIs have a 44% increased risk of developing dementia
(Natural News) Millions of Americans are coping with gastroesophageal reflux disease, and proton pump inhibitors are one of the most popular drugs for treating it. In years past, some 15 million people in the United States were taking a prescription proton pump inhibitor (PPI) to treat their gastroesophageal reflux disease (GERD). The drugs work by reducing... (Source: NaturalNews.com)
Source: NaturalNews.com - November 27, 2018 Category: Consumer Health News Source Type: news

Risk of fall in patients taking proton pump inhibitors: a meta-analysis - Lapumnuaypol K, Thongprayoon C, Wijarnpreecha K, Tiu A, Cheungpasitporn W.
BACKGROUND: Fall prevention among older adults is a worldwide public health advocacy because of negative consequences of fall. Recent studies have shown that proton pump inhibitors (PPIs) increase the risk of fall. PPIs are among the widely prescribed medi... (Source: SafetyLit)
Source: SafetyLit - October 31, 2018 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Antibiotics, H2RAs and PPIs linked to child obesity
Microbiota-altering medications in early childhood might influence weight gain, finds research Related items fromOnMedica Weight-loss surgery doubles in two years Adjuvanted trivalent flu vaccine best option for over-65s Flu nasal spray fine for children with egg allergy Texting can improve flu jab uptake Scotland reveals target of halving child obesity by 2030 (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 31, 2018 Category: UK Health Source Type: news

Proton Pump Inhibitor Doesn't Reduce ICU Mortality Proton Pump Inhibitor Doesn't Reduce ICU Mortality
Giving intensive care unit (ICU) patients a proton-pump inhibitor (PPI) to prevent gastrointestinal bleeding does not seem to affect mortality, according to a European trial of nearly 3,300 adults.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - October 26, 2018 Category: Intensive Care Tags: Critical Care News Source Type: news

Risk of Adverse CV Events With PPIs Independent of Clopidogrel Risk of Adverse CV Events With PPIs Independent of Clopidogrel
This study aimed to determine whether the observed increase in cardiovascular risk of PPI use with anti-platelet therapy is conferred by PPIs directly or by a pharmacokinetic interaction.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 26, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Adverse Effects of PPIs: Fact or Fake News? Adverse Effects of PPIs: Fact or Fake News?
Recent media reports have ascribed serious adverse effects to proton pump inhibitors, raising concerns in both patients and providers. Is there good clinical evidence to back up these assertions?Current Opinion in Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 26, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Impact of PPIs on Spontaneous Bacterial Peritonitis Impact of PPIs on Spontaneous Bacterial Peritonitis
In what ways might the dosages of proton pump inhibitors affect the incidence and clinical course of spontaneous bacterial peritonitis?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 18, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Use of Different PPIs and Microscopic Colitis Use of Different PPIs and Microscopic Colitis
This study examined the impact of timing, dose and choice of PPI.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 17, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

PPIs Tied to Hip Fracture in Dialysis Patients (CME/CE)
(MedPage Today) -- But H2 blockers were exonerated (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 27, 2018 Category: Gastroenterology Source Type: news

PPIs and Long-Term Risk of Pneumonia in Older Adults PPIs and Long-Term Risk of Pneumonia in Older Adults
Might long-term use of proton-pump inhibitors increase pneumonia risk in the elderly?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 20, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Reducing Risk of Esophageal Cancer in Barrett's Esophagus Reducing Risk of Esophageal Cancer in Barrett's Esophagus
Patients with Barrett's esophagus have a high risk of developing esophageal adenocarcinoma. Can PPIs and H2 receptor antagonists mitigate the risk?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 18, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Association Between PPIs and Hepatocellular Carcinoma Association Between PPIs and Hepatocellular Carcinoma
Might long-term use of proton pump inhibitors increase the risk of hepatocellular carcinoma?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 13, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Long-Term PPI Use Linked to Pneumonia Risk in Older Adults
THURSDAY, Aug. 23, 2018 -- Among older adults in primary care, use of proton pump inhibitors (PPIs) is associated with greater risk of pneumonia in the second year of treatment, according to a study published in the July issue of the Journal of the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 23, 2018 Category: Pharmaceuticals Source Type: news

Slow Medicine: Discontinuing PPIs
(MedPage Today) -- Plus waiting for the evidence on screening for Afib and selecting basal insulins (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 8, 2018 Category: Primary Care Source Type: news

PPI and H2 Receptor Antagonist Use and Risk of Liver Cancer PPI and H2 Receptor Antagonist Use and Risk of Liver Cancer
Do PPIs and H2 receptor antagonists contribute to the risk of primary liver cancer?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 2, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

High-Dose PPI Plus Aspirin Reduced Esophageal Cancer Risk
Combination therapy with a high-dose proton pump inhibitor and aspirin reduced the risk of progression to esophageal cancer in patients with Barrett esophagus. (Source: CancerNetwork)
Source: CancerNetwork - July 2, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Source Type: news

Alzheimer's Disease, PPI Use, and Risk of Hip Fracture Alzheimer's Disease, PPI Use, and Risk of Hip Fracture
Does long-term use of a proton pump inhibitor increase the risk of hip fracture among persons with Alzheimer's disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 12, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

When PPIs Don't Work for Reflux, Surgery Beats Drugs When PPIs Don't Work for Reflux, Surgery Beats Drugs
After rigorous testing excludes other causes of gastroesophageal reflux disease in patients refractory to proton pump inhibitors (PPIs), fundoplication surgery can be an answer, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 5, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Aspirin Plus PPI Prevents Esophageal Cancer Aspirin Plus PPI Prevents Esophageal Cancer
Barrett's esophagus doesn't commonly progress to cancer, but there is a risk; chemoprevention with aspirin plus proton pump inhibitor (PPI) works, but also carries a risk.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 5, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Over-the-counter acid-reflux drugs may cause pneumonia, study finds
Researchers from the University of Exeter found that taking proton pump inhibitors (PPIs) for at least a year is significantly linked to people developing the lung condition. (Source: the Mail online | Health)
Source: the Mail online | Health - April 25, 2018 Category: Consumer Health News Source Type: news

Commonly prescribed heartburn drug linked to pneumonia in older adults
(American Geriatrics Society) Researchers at the University of Exeter have found a statistical link between pneumonia in older people and a group of medicines commonly used to neutralize stomach acid in people with heartburn or stomach ulcers. Although proton-pump inhibitors (PPIs) are still a valuable group of medicines, research is indicating that PPIs are not as completely safe for older people as previously thought. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 24, 2018 Category: Infectious Diseases Source Type: news

PPIs Not Tied to First-Time Strokes (CME/CE)
(MedPage Today) -- Increased risk attenuated after adjusting for lifestyle factors, clinical indications (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 10, 2018 Category: Cardiology Source Type: news

OTC meds for acid reflux linked to depression - Proton Pump Inhibitors
(Natural News) One of the quickest ways to initiate depression physiologically is to destroy your intestinal microbiota and block your body’s ability to utilize nutrients. Medications for acid reflux do just that. Proton pump inhibitors (PPIs) are prescribed to reduce stomach acid, but in the process, they damage the colonization of your microbiota, severely altering the... (Source: NaturalNews.com)
Source: NaturalNews.com - April 3, 2018 Category: Consumer Health News Source Type: news

Proton pump inhibitors linked to increased risk of depression due to destructive effects on gut microbiota
(Natural News) New research published in the journal Psychotherapy and Psychosomatics has identified a strong and seemingly causal link between proton pump inhibitor (PPI) drugs for stomach acid reduction and severe depression, which researchers say is probably a result of the way these drugs severely disrupt the gut microbiome. The study’s comparative analysis looked at... (Source: NaturalNews.com)
Source: NaturalNews.com - March 29, 2018 Category: Consumer Health News Source Type: news

Yosprala(TM) in At-Risk Patients Requiring Low-Dose Aspirin Yosprala(TM) in At-Risk Patients Requiring Low-Dose Aspirin
Do the benefits of Yosprala(TM) therapy outweigh its costs when compared with combination therapy with aspirin and a proton-pump inhibitor taken as individual products?Medscape Pharmacists (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 27, 2018 Category: Consumer Health News Tags: Pharmacist Ask the Expert Source Type: news

Long-term PPI use ‘does not’ increase Alzheimer’s hip fracture risk
Long-term proton pump inhibitor (PPI) use does not increase the risk of hip fracture among patients with Alzheimer ’s disease, according to researchers. (Source: Nursing Times)
Source: Nursing Times - March 14, 2018 Category: Nursing Source Type: news

Over-the-counter acid reflux drugs could cause depression
Researchers from Taipei Veterans General Hospital in Taiwan believe PPIs may alter guts' bacterial make-up. Past studies suggest a link between the microbiome and mental health. (Source: the Mail online | Health)
Source: the Mail online | Health - March 8, 2018 Category: Consumer Health News Source Type: news

Proton Pump Inhibitor Use and Dementia Risk Proton Pump Inhibitor Use and Dementia Risk
Prior studies have suggested a potentially troubling link between PPI use and dementia risk, but this new study found no significantly greater risk of dementia in elderly long-term PPI users.Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 7, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Long-term PPI Use and Increased Esophageal CA Risk Long-term PPI Use and Increased Esophageal CA Risk
A single cohort study shows an increased risk for esophageal cancer in patients taking long-term proton-pump inhibitor (PPI) therapy, but experts are skeptical about the finding.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 5, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

PPIs and CV Safety: Good Science to the Rescue PPIs and CV Safety: Good Science to the Rescue
Amid the controversy, Dr David Johnson reviews new research supporting the cardiovascular safety of PPIs.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 28, 2018 Category: Consumer Health News Tags: Gastroenterology Viewpoint Source Type: news

PPIs in Noncirrhotic Patients With Chronic HCV Infection PPIs in Noncirrhotic Patients With Chronic HCV Infection
This study assessed the impact of proton pump inhibitors on the progression of liver disease in noncirrhotic patients with hepatitis C virus infection. Are PPIs safe to use in these patients?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 27, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Long-term use of PPIs Not Associated with Cognitive Decline (CME/CE)
(MedPage Today) -- Population-based analyses of Danish Twin cohorts of middle-aged and older patients (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 14, 2018 Category: Psychiatry Source Type: news

Your NEJM Group Today: Acute Pyelonephritis Clinical Pearls / PPIs & Stroke? / Connecticut Primary Care Opportunities
Here's what we chose for you from NEJM Group today: NEJM Resident 360: Clinical Pearls: What are the typical manifestations of acute pyelonephritis? What is... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 8, 2018 Category: Primary Care Source Type: news

Heartburn is a symptom – and meds are NOT the solution: Prescriptions for heartburn DOUBLE your risk of stomach cancer
(Natural News) Prescribed drugs for heartburn increase the risk of stomach cancer by two times, according to an article published in the Daily Mail. An observational study carried out by researchers from the University College London revealed that individuals who use proton pump inhibitors (PPIs) to treat chronic heartburn even at the recommended time of two... (Source: NaturalNews.com)
Source: NaturalNews.com - January 4, 2018 Category: Consumer Health News Source Type: news

Proton Pump Inhibitors, Nephropathy, and CVD in T2D Proton Pump Inhibitors, Nephropathy, and CVD in T2D
How might long-term proton pump inhibitor use impact nephropathy and cardiovascular disease risk among patients with type 2 diabetes?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 7, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

New PPI Use Not Tied to Excess Risk of Heart Attack New PPI Use Not Tied to Excess Risk of Heart Attack
Privately insured patients who take newly prescribed proton pump inhibitors (PPIs) are no more likely than their peers on prescription histamine-2 receptor antagonists (H2RAs) to have a myocardial infarction (MI) over the next three years, according to new findings.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 30, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

PPIs and Risk of Mild Cognitive Impairment and Dementia PPIs and Risk of Mild Cognitive Impairment and Dementia
A new study allays concern about the safety of PPIs with respect to cognitive function, including increased risk of dementia and Alzheimer's disease--in contrast to prior reports.Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 29, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Your NEJM Group Today: Hip Fracture Case / PPIs & MI Risk / Florida Primary Care Opportunity
Take a look at today's offering from NEJM Group: NEJM Clinical Practice Center: Clinical Practice Article: A 65-year-old woman who's been healthy and... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 27, 2017 Category: Primary Care Source Type: news

DOUBLE your risk of stomach cancer with acid reflux drugs, study claims
(Natural News) A new study claims that you could double your risk of developing stomach cancer by mindlessly taking acid reflux drugs. The report stated that proton pump inhibitors (PPIs) greatly increase a person’s risk of having gastrointestinal tumors. Some of the known PPIs are Prilosec, Prevacid, and Protonix. The study showed data from 63,397 individually-monitored adults who... (Source: NaturalNews.com)
Source: NaturalNews.com - November 27, 2017 Category: Consumer Health News Source Type: news

Taking proton pump inhibitors not linked to higher dementia risk
(American Geriatrics Society) In a new research article published in the Journal of the American Geriatrics Society, scientists were able to conclude that developing dementia or Alzheimer's disease (the most common form of dementia) did not appear to be linked to taking proton pump inhibitors (PPIs). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2017 Category: International Medicine & Public Health Source Type: news

EndoGastric Solutions touts more MAC reimbursement wins for Esophyx device
EndoGastric Solutions said today that new Medicare Administrative Contractors Noridian Health Care Solutions and National Government Services have been granted reimbursement access for the transoral incisionless fundoplication procedure using its Esophyx device. The Redmond, Wash.-based company’s TIF procedure is designed to prevent stomach acids refluxing back into the esophagus by reconstructing the gastroesophageal valve. Noridian, which provides coverage for more than 10.7 million Medicare beneficiaries in 13 states, made the reimbursement decision effective October 27, while NGS, which covers approximately 10.1 ...
Source: Mass Device - November 14, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Otolaryngology Ear, Nose & Throat endogastricsolutions Source Type: news

Common Heartburn Meds Show Ties to Kidney Trouble
The medicines in question are called proton pump inhibitors (PPIs). They reduce stomach acid production and are among the most widely prescribed medications in the world. (Source: WebMD Health)
Source: WebMD Health - November 4, 2017 Category: Consumer Health News Source Type: news

Long-term PPI use linked to doubled risk for stomach cancer: Study
A study at University College London and the University of Hong Kong suggests long-term use of PPIs for acid reflux may double the risk for stomach cancer. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 1, 2017 Category: Consumer Health News Source Type: news

Acid reflux drugs linked to increased stomach cancer risk
Conclusion PPIs are commonly used medicines for acid reflux. This may seem like alarming news for the many people in the UK who take them, but it's important to remember that the overall risk of stomach cancer is still very low. This study has several limitations that mean we should be cautious about the results: This type of study can't prove PPIs caused the increased risk of cancer. The increased risk could be down to other factors. Researchers were unable to adjust their figures to take account of some relevant confounding factors, such as alcohol and tobacco use, as these weren't routinely recorded. Almost all the pati...
Source: NHS News Feed - November 1, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

Acid reflux pills 'raise risk of cancer by eight-fold'
Scientists say people who regularly use proton pump inhibitors (PPIs) – common drugs used to treat acid reflux – are twice as likely to develop the cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2017 Category: Consumer Health News Source Type: news

PPI Use After H. pylori Eradication Therapy Tied to Increased Risk for Gastric Cancer (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Long-term use of proton-pump inhibitors (PPIs) after treatment for Helicobacter pylori infection is associated with increased risk for gastric cancer, according to a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 1, 2017 Category: Primary Care Source Type: news

Long-term use of PPIs linked to doubling in stomach cancer risk
Risk rose with dose and duration of treatment after H pylori eradication Related items fromOnMedica Proton pump inhibitors associated with raised mortality Oesophageal and stomach cancer linked to early adulthood overweight Experts link alcohol to stomach cancer (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 1, 2017 Category: UK Health Source Type: news

Acid reflux drug linked to more than doubled risk of stomach cancer – study
There are more than 50m prescriptions for proton pump inhibitors in the UK, though they have previously been linked to side-effects and increased risk of deathA drug commonly used to treat acid reflux is linked to a more than doubled risk of developing stomach cancer, researchers have claimed.Proton pump inhibitors (PPIs) reduce the amount of acid made by the stomach and are used to treat acid reflux and stomach ulcers.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 31, 2017 Category: Science Authors: Press Association Tags: Drugs Cancer Health Society Science Source Type: news