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Your NEJM Group Today: Acute Pyelonephritis Clinical Pearls / PPIs & Stroke? / Connecticut Primary Care Opportunities
Here's what we chose for you from NEJM Group today: NEJM Resident 360: Clinical Pearls: What are the typical manifestations of acute pyelonephritis? What is... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 8, 2018 Category: Primary Care Source Type: news

Heartburn is a symptom – and meds are NOT the solution: Prescriptions for heartburn DOUBLE your risk of stomach cancer
(Natural News) Prescribed drugs for heartburn increase the risk of stomach cancer by two times, according to an article published in the Daily Mail. An observational study carried out by researchers from the University College London revealed that individuals who use proton pump inhibitors (PPIs) to treat chronic heartburn even at the recommended time of two... (Source: NaturalNews.com)
Source: NaturalNews.com - January 4, 2018 Category: Consumer Health News Source Type: news

Proton Pump Inhibitors, Nephropathy, and CVD in T2D Proton Pump Inhibitors, Nephropathy, and CVD in T2D
How might long-term proton pump inhibitor use impact nephropathy and cardiovascular disease risk among patients with type 2 diabetes?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 7, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

New PPI Use Not Tied to Excess Risk of Heart Attack New PPI Use Not Tied to Excess Risk of Heart Attack
Privately insured patients who take newly prescribed proton pump inhibitors (PPIs) are no more likely than their peers on prescription histamine-2 receptor antagonists (H2RAs) to have a myocardial infarction (MI) over the next three years, according to new findings.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 30, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

PPIs and Risk of Mild Cognitive Impairment and Dementia PPIs and Risk of Mild Cognitive Impairment and Dementia
A new study allays concern about the safety of PPIs with respect to cognitive function, including increased risk of dementia and Alzheimer's disease--in contrast to prior reports.Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 29, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Your NEJM Group Today: Hip Fracture Case / PPIs & MI Risk / Florida Primary Care Opportunity
Take a look at today's offering from NEJM Group: NEJM Clinical Practice Center: Clinical Practice Article: A 65-year-old woman who's been healthy and... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 27, 2017 Category: Primary Care Source Type: news

DOUBLE your risk of stomach cancer with acid reflux drugs, study claims
(Natural News) A new study claims that you could double your risk of developing stomach cancer by mindlessly taking acid reflux drugs. The report stated that proton pump inhibitors (PPIs) greatly increase a person’s risk of having gastrointestinal tumors. Some of the known PPIs are Prilosec, Prevacid, and Protonix. The study showed data from 63,397 individually-monitored adults who... (Source: NaturalNews.com)
Source: NaturalNews.com - November 27, 2017 Category: Consumer Health News Source Type: news

Taking proton pump inhibitors not linked to higher dementia risk
(American Geriatrics Society) In a new research article published in the Journal of the American Geriatrics Society, scientists were able to conclude that developing dementia or Alzheimer's disease (the most common form of dementia) did not appear to be linked to taking proton pump inhibitors (PPIs). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2017 Category: International Medicine & Public Health Source Type: news

EndoGastric Solutions touts more MAC reimbursement wins for Esophyx device
EndoGastric Solutions said today that new Medicare Administrative Contractors Noridian Health Care Solutions and National Government Services have been granted reimbursement access for the transoral incisionless fundoplication procedure using its Esophyx device. The Redmond, Wash.-based company’s TIF procedure is designed to prevent stomach acids refluxing back into the esophagus by reconstructing the gastroesophageal valve. Noridian, which provides coverage for more than 10.7 million Medicare beneficiaries in 13 states, made the reimbursement decision effective October 27, while NGS, which covers approximately 10.1 ...
Source: Mass Device - November 14, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Otolaryngology Ear, Nose & Throat endogastricsolutions Source Type: news

Common Heartburn Meds Show Ties to Kidney Trouble
The medicines in question are called proton pump inhibitors (PPIs). They reduce stomach acid production and are among the most widely prescribed medications in the world. (Source: WebMD Health)
Source: WebMD Health - November 4, 2017 Category: Consumer Health News Source Type: news

Long-term PPI use linked to doubled risk for stomach cancer: Study
A study at University College London and the University of Hong Kong suggests long-term use of PPIs for acid reflux may double the risk for stomach cancer. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 1, 2017 Category: Consumer Health News Source Type: news

Acid reflux drugs linked to increased stomach cancer risk
Conclusion PPIs are commonly used medicines for acid reflux. This may seem like alarming news for the many people in the UK who take them, but it's important to remember that the overall risk of stomach cancer is still very low. This study has several limitations that mean we should be cautious about the results: This type of study can't prove PPIs caused the increased risk of cancer. The increased risk could be down to other factors. Researchers were unable to adjust their figures to take account of some relevant confounding factors, such as alcohol and tobacco use, as these weren't routinely recorded. Almost all the pati...
Source: NHS News Feed - November 1, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

Acid reflux pills 'raise risk of cancer by eight-fold'
Scientists say people who regularly use proton pump inhibitors (PPIs) – common drugs used to treat acid reflux – are twice as likely to develop the cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2017 Category: Consumer Health News Source Type: news

PPI Use After H. pylori Eradication Therapy Tied to Increased Risk for Gastric Cancer (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Long-term use of proton-pump inhibitors (PPIs) after treatment for Helicobacter pylori infection is associated with increased risk for gastric cancer, according to a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 1, 2017 Category: Primary Care Source Type: news

Long-term use of PPIs linked to doubling in stomach cancer risk
Risk rose with dose and duration of treatment after H pylori eradication Related items fromOnMedica Proton pump inhibitors associated with raised mortality Oesophageal and stomach cancer linked to early adulthood overweight Experts link alcohol to stomach cancer (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 1, 2017 Category: UK Health Source Type: news

Acid reflux drug linked to more than doubled risk of stomach cancer – study
There are more than 50m prescriptions for proton pump inhibitors in the UK, though they have previously been linked to side-effects and increased risk of deathA drug commonly used to treat acid reflux is linked to a more than doubled risk of developing stomach cancer, researchers have claimed.Proton pump inhibitors (PPIs) reduce the amount of acid made by the stomach and are used to treat acid reflux and stomach ulcers.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 31, 2017 Category: Science Authors: Press Association Tags: Drugs Cancer Health Society Science Source Type: news

Gastric Cancer Risk Doubled With Long-term PPI Use Gastric Cancer Risk Doubled With Long-term PPI Use
The risk for gastric cancer increases with the dose and duration of proton-pump inhibitor use after successful H pylori eradication.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 31, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Long-term PPI Use Tied to Doubled Risk for Gastric Cancer Long-term PPI Use Tied to Doubled Risk for Gastric Cancer
The risk for gastric cancer increases with the dose and duration of proton-pump inhibitor use after successful H pylori eradication.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 31, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Are Some Heartburn Meds Tied to Stomach Cancer?
TUESDAY, Oct. 31, 2017 -- Popping certain heartburn drugs like they're candy might up your odds for stomach cancer, new research suggests. The risk was proportionate to how long and how often these drugs, called proton pump inhibitors (PPIs), were... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 31, 2017 Category: General Medicine Source Type: news

New Guidelines Support Deprescribing of Proton Pump Inhibitors
Deprescribing proton pump inhibitors (PPIs) in asymptomatic patients who do not truly need treatment can be accomplished through reductions in both dosage and dosing frequency, David S. H. Lee, PharmD, PhD, said at the annual meeting of the American Geriatrics Society in May 2017. (Source: Caring for the Ages)
Source: Caring for the Ages - October 28, 2017 Category: Health Management Authors: Christine Kilgore Source Type: news

PFO Closure Reduces Strokes, and PPIs Increase Dementia Risk? PFO Closure Reduces Strokes, and PPIs Increase Dementia Risk?
New research suggests that reducing patent foramen ovale size could lessen stroke risk, while other work explores the role that PPIs might play in causing dementia.Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 17, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery Commentary Source Type: news

PPIs vs. NSAIDs
Title: PPIs vs. NSAIDsCategory: MedicationsCreated: 10/12/2017 12:00:00 AMLast Editorial Review: 10/12/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - October 12, 2017 Category: Drugs & Pharmacology Source Type: news

Study finds no evidence linking reflux medicines to bone fractures
A new study in Alimentary Pharmacology& Therapeutics reports that proton pump inhibitors (PPIs) are not linked to an increased risk of bone fractures or bone thinning, as it was previously believed.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 10, 2017 Category: Endocrinology Source Type: news

Common acid reflux medications promote chronic liver disease
(University of California - San Diego) Approximately 10 percent of Americans take a proton pump inhibitor drug to relieve symptoms of frequent heartburn and acid reflux. That percentage can be much higher for people with chronic liver disease. Researchers at University of California San Diego School of Medicine have discovered evidence in mice and humans that these medications alter gut bacteria in a way that promotes three types of chronic liver disease. The study is published Oct. 10 in Nature Communications. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - October 10, 2017 Category: International Medicine & Public Health Source Type: news

Woman cured of acid reflux that left her unable to swallow
EXCLUSIVE: Anna Lavinas, from Croydon, struggled with her heartburn ever since childhood. Drugs designed to help combat her reflux, known as PPIs, all failed. (Source: the Mail online | Health)
Source: the Mail online | Health - September 14, 2017 Category: Consumer Health News Source Type: news

Could a Mediterranean diet be as good as drugs for acid reflux?
Conclusion The results of this relatively small cohort study seem to show that a plant-based Mediterranean diet with alkaline water is equally good as PPI medication at treating acid reflux symptoms when people also follow standard advice to cut out certain things from their diet. This might suggest that the first port of call for people with gastro-oesophageal reflux could be to try a Mediterranean diet before going on PPI medication, to avoid potential side effects. There are, however, some limitations to this research: Cohort studies can only show links and cannot prove definite cause and effect, and retrospective coh...
Source: NHS News Feed - September 8, 2017 Category: Consumer Health News Tags: Food/diet Source Type: news

Dietary Treatment May Be as Good as PPIs for Laryngopharyngeal Reflux (FREE)
By Cara Adler Edited by Andr é Sofair, MD, MPH A dietary approach is at least as effective as proton pump inhibitor (PPI) therapy for treating symptoms of laryngopharyngeal reflux, according to a retrospective chart review study in JAMA Otolaryngology—Head& … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 8, 2017 Category: Primary Care Source Type: news

Consider plant-based diet for treating reflux symptoms
PPIs no better than plant-based Mediterranean diet plus alkaline water at improving LPR symptoms, research suggests Related items fromOnMedica Oesophageal and stomach cancer linked to early adulthood overweight Plant protein consumption linked to increased longevity Plant-based diet not always best for heart health (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 8, 2017 Category: UK Health Source Type: news

PPIs Not Superior to Dietary Intervention for Reflux PPIs Not Superior to Dietary Intervention for Reflux
Patients treating their laryngopharyngeal reflux with a healthy, mostly plant-based diet and alkaline water experienced fewer symptoms than those taking PPIs in a retrospective study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 7, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Mediterranean diet is the best cure for acid reflux
Patients who ate fish, vegetables and whole grains reported a greater reduction in symptoms than those on proton pump inhibitors (PPIs), the study by New York Medical College found. (Source: the Mail online | Health)
Source: the Mail online | Health - September 7, 2017 Category: Consumer Health News Source Type: news

PPIs Linked With Dementia? Latest Evidence Says No PPIs Linked With Dementia? Latest Evidence Says No
Dr David Johnson looks at two new reports that may dismiss this association, thereby relieving our patients'worrying.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 17, 2017 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

FDA Drug Safety Communication: Possible increased risk of fractures of the hip, wrist, and spine with the use of proton pump inhibitors
Update: 3/23/2011 FDA has determined an osteoporosis and fracture warning on the over-the-counter (OTC) proton pump inhibitor (PPI) medication “Drug Facts” label is not indicated at this time. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Your NEJM Group Today: Concerns About Gabapentin for Pain / PPIs & Dementia / California IM Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Audio Interview: Treating Pain with Gabapentinoids: Dr. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 3, 2017 Category: Primary Care Source Type: news

Long-Term PPIs May Be Overused in Nursing Homes
Results from a large multicenter, cross-sectional study suggest that nearly half of nursing home residents receiving proton pump inhibitors (PPIs) were prescribed the drugs for “non-evidence-based indications.” (Source: Caring for the Ages)
Source: Caring for the Ages - July 28, 2017 Category: Health Management Authors: Braxton Poe Source Type: news

PPI drugs warning: Study finds 50% increased risk of death from long-term use of Proton Pump Inhibitors
(Natural News) PPI drugs commonly used to mask the symptoms of heartburn have been found to increase the risk of death by 50%, according to a new study carried out at the Washington University School of Medicine. As Natural News reports: PPIs, which are readily available over the counter under brand names such as Prevacid,... (Source: NaturalNews.com)
Source: NaturalNews.com - July 27, 2017 Category: Consumer Health News Source Type: news

PPIs Not Linked to Cognitive Decline, Study Finds PPIs Not Linked to Cognitive Decline, Study Finds
Proton pump inhibitor use was not associated with cognitive decline, a study has found; previous studies showed an association between use of the drugs and dementia, however.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 25, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Mortality and Long-Term PPIs: Pharmacy Practice News Report
(MedPage Today) -- Also, opioids prescriptions in the U.S. on decline (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - July 19, 2017 Category: Urology & Nephrology Source Type: news

Heartburn drugs (Proton Pump Inhibitors) linked to sudden death risk
(Natural News) Extended use of proton pump inhibitors (PPIs), a popular type of heartburn drug, dramatically increases the risk of death. This was the conclusion of a team of researchers from the Washington University School of Medicine after analyzing medical data of some 300,000 people. Authors of the study say that their findings indicate the... (Source: NaturalNews.com)
Source: NaturalNews.com - July 10, 2017 Category: Consumer Health News Source Type: news

Your NEJM Group Today: More Geriatricians Needed / PPIs & Chronic Kidney Disease / Arkansas Hem-Onc Opportunities (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Catalyst: Expert … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 7, 2017 Category: Primary Care Source Type: news

Deprescribing PPIs: An Algorithm Deprescribing PPIs: An Algorithm
New guidelines make it easier to decide when to stop a PPI, reduce the dose or frequency, or change to a different drug altogether.Medscape Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 6, 2017 Category: Consumer Health News Tags: Family Medicine/Primary Care Article Source Type: news

Study Finds Increased Mortality Risk with PPI Use (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Proton-pump inhibitor use is associated with increased mortality risk, finds a study in BMJ Open.Using data from the U.S. Department … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 5, 2017 Category: Primary Care Source Type: news

Heartburn drugs linked to premature death
Conclusion This larger set of observational data finds that PPI drugs are associated with an increase in the risk of early death compared with either H2 blockers or no acid suppression drugs. This was the case for participants both with and without gastrointestinal problems. It also appears as though the longer the PPIs drugs are taken, the greater the risk of death. Considering that these drugs are widely used in the UK, these findings may cause concern. But the research has a number of important limitations: The study was conducted in a population of mostly white, older US male veterans, which might limit the abi...
Source: NHS News Feed - July 4, 2017 Category: Consumer Health News Tags: Medication Source Type: news

Some heartburn drugs linked with higher risk of death
Study looked at patients who'd taken proton pump inhibitors, or PPIs, including popular brands like Prilosec, Nexium and Prevacid (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - July 4, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Common heartburn drugs tied to higher risk of death
A large study finds that PPIs - used by millions for heartburn and ulcers - are linked to higher risk of death and that the risk rises the longer the use. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 4, 2017 Category: Consumer Health News Tags: Acid Reflux / GERD Source Type: news

People taking heartburn drugs could have higher risk of death, study claims
Research suggests people on proton pump inhibitors are more likely to die than those taking different antacid or none at allMillions of people taking common heartburn andindigestion medications could be at an increased risk of death, research suggests.The drugs, known as proton pump inhibitors (PPIs), neutralise the acid in the stomach and are widely prescribed, with low doses also available without prescription from pharmacies. In the UK, doctors issue more than 50m prescriptions for PPIs every year.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 4, 2017 Category: Science Authors: James Rudd Tags: Drugs Health Science Society UK news Source Type: news

Proton pump inhibitors associated with raised mortality
Researchers suggest restricting indications for use of PPIs, and treatment duration Related items fromOnMedica Barrett ’s oesophagus (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 4, 2017 Category: UK Health Source Type: news

PPIs Linked With Higher Risk for Death PPIs Linked With Higher Risk for Death
Use and duration of proton-pump inhibitors should be limited to medical indications, researchers say. An expert agrees but says the excess risk is small and the drugs are still often the best option.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 3, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

PPIs Not Found to Raise Risk of Alzheimer ’ s Disease
New research debunks other studies suggesting that PPIs cause mental decline (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - June 29, 2017 Category: Psychiatry Tags: Family Medicine, Geriatrics, Gastroenterology, Internal Medicine, Neurology, Nursing, Pharmacy, Psychiatry, Journal, Source Type: news

Popular Heartburn Meds Don't Raise Alzheimer's Risk: Study
WEDNESDAY, June 28, 2017 -- Drugs used to treat acid reflux and ulcers don't appear to boost the risk of dementia, as has been previously suspected, new research suggests. The study focused on widely used proton pump inhibitors (PPIs) drugs --... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 28, 2017 Category: General Medicine Source Type: news

PPI-responsive Esophageal Eosinophilia: A Valid Diagnosis? PPI-responsive Esophageal Eosinophilia: A Valid Diagnosis?
Is proton pump inhibitor-responsive esophageal eosinophilia just an arbitrary construct, or does it have a distinct molecular and mechanistic basis? Explore the controversy in this article.Current Opinion in Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 28, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news