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Could a Mediterranean diet be as good as drugs for acid reflux?
Conclusion The results of this relatively small cohort study seem to show that a plant-based Mediterranean diet with alkaline water is equally good as PPI medication at treating acid reflux symptoms when people also follow standard advice to cut out certain things from their diet. This might suggest that the first port of call for people with gastro-oesophageal reflux could be to try a Mediterranean diet before going on PPI medication, to avoid potential side effects. There are, however, some limitations to this research: Cohort studies can only show links and cannot prove definite cause and effect, and retrospective coh...
Source: NHS News Feed - September 8, 2017 Category: Consumer Health News Tags: Food/diet Source Type: news

Dietary Treatment May Be as Good as PPIs for Laryngopharyngeal Reflux (FREE)
By Cara Adler Edited by Andr é Sofair, MD, MPH A dietary approach is at least as effective as proton pump inhibitor (PPI) therapy for treating symptoms of laryngopharyngeal reflux, according to a retrospective chart review study in JAMA Otolaryngology—Head& … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 8, 2017 Category: Primary Care Source Type: news

Consider plant-based diet for treating reflux symptoms
PPIs no better than plant-based Mediterranean diet plus alkaline water at improving LPR symptoms, research suggests Related items fromOnMedica Oesophageal and stomach cancer linked to early adulthood overweight Plant protein consumption linked to increased longevity Plant-based diet not always best for heart health (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 8, 2017 Category: UK Health Source Type: news

PPIs Not Superior to Dietary Intervention for Reflux PPIs Not Superior to Dietary Intervention for Reflux
Patients treating their laryngopharyngeal reflux with a healthy, mostly plant-based diet and alkaline water experienced fewer symptoms than those taking PPIs in a retrospective study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 7, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Mediterranean diet is the best cure for acid reflux
Patients who ate fish, vegetables and whole grains reported a greater reduction in symptoms than those on proton pump inhibitors (PPIs), the study by New York Medical College found. (Source: the Mail online | Health)
Source: the Mail online | Health - September 7, 2017 Category: Consumer Health News Source Type: news

PPIs Linked With Dementia? Latest Evidence Says No PPIs Linked With Dementia? Latest Evidence Says No
Dr David Johnson looks at two new reports that may dismiss this association, thereby relieving our patients'worrying.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 17, 2017 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

FDA Drug Safety Communication: Possible increased risk of fractures of the hip, wrist, and spine with the use of proton pump inhibitors
Update: 3/23/2011 FDA has determined an osteoporosis and fracture warning on the over-the-counter (OTC) proton pump inhibitor (PPI) medication “Drug Facts” label is not indicated at this time. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Your NEJM Group Today: Concerns About Gabapentin for Pain / PPIs & Dementia / California IM Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Audio Interview: Treating Pain with Gabapentinoids: Dr. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 3, 2017 Category: Primary Care Source Type: news

Long-Term PPIs May Be Overused in Nursing Homes
Results from a large multicenter, cross-sectional study suggest that nearly half of nursing home residents receiving proton pump inhibitors (PPIs) were prescribed the drugs for “non-evidence-based indications.” (Source: Caring for the Ages)
Source: Caring for the Ages - July 28, 2017 Category: Health Management Authors: Braxton Poe Source Type: news

PPI drugs warning: Study finds 50% increased risk of death from long-term use of Proton Pump Inhibitors
(Natural News) PPI drugs commonly used to mask the symptoms of heartburn have been found to increase the risk of death by 50%, according to a new study carried out at the Washington University School of Medicine. As Natural News reports: PPIs, which are readily available over the counter under brand names such as Prevacid,... (Source: NaturalNews.com)
Source: NaturalNews.com - July 27, 2017 Category: Consumer Health News Source Type: news

PPIs Not Linked to Cognitive Decline, Study Finds PPIs Not Linked to Cognitive Decline, Study Finds
Proton pump inhibitor use was not associated with cognitive decline, a study has found; previous studies showed an association between use of the drugs and dementia, however.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 25, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Mortality and Long-Term PPIs: Pharmacy Practice News Report
(MedPage Today) -- Also, opioids prescriptions in the U.S. on decline (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - July 19, 2017 Category: Urology & Nephrology Source Type: news

Heartburn drugs (Proton Pump Inhibitors) linked to sudden death risk
(Natural News) Extended use of proton pump inhibitors (PPIs), a popular type of heartburn drug, dramatically increases the risk of death. This was the conclusion of a team of researchers from the Washington University School of Medicine after analyzing medical data of some 300,000 people. Authors of the study say that their findings indicate the... (Source: NaturalNews.com)
Source: NaturalNews.com - July 10, 2017 Category: Consumer Health News Source Type: news

Your NEJM Group Today: More Geriatricians Needed / PPIs & Chronic Kidney Disease / Arkansas Hem-Onc Opportunities (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Catalyst: Expert … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 7, 2017 Category: Primary Care Source Type: news

Deprescribing PPIs: An Algorithm Deprescribing PPIs: An Algorithm
New guidelines make it easier to decide when to stop a PPI, reduce the dose or frequency, or change to a different drug altogether.Medscape Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 6, 2017 Category: Consumer Health News Tags: Family Medicine/Primary Care Article Source Type: news

Study Finds Increased Mortality Risk with PPI Use (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Proton-pump inhibitor use is associated with increased mortality risk, finds a study in BMJ Open.Using data from the U.S. Department … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 5, 2017 Category: Primary Care Source Type: news

Heartburn drugs linked to premature death
Conclusion This larger set of observational data finds that PPI drugs are associated with an increase in the risk of early death compared with either H2 blockers or no acid suppression drugs. This was the case for participants both with and without gastrointestinal problems. It also appears as though the longer the PPIs drugs are taken, the greater the risk of death. Considering that these drugs are widely used in the UK, these findings may cause concern. But the research has a number of important limitations: The study was conducted in a population of mostly white, older US male veterans, which might limit the abi...
Source: NHS News Feed - July 4, 2017 Category: Consumer Health News Tags: Medication Source Type: news

Some heartburn drugs linked with higher risk of death
Study looked at patients who'd taken proton pump inhibitors, or PPIs, including popular brands like Prilosec, Nexium and Prevacid (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - July 4, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Common heartburn drugs tied to higher risk of death
A large study finds that PPIs - used by millions for heartburn and ulcers - are linked to higher risk of death and that the risk rises the longer the use. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 4, 2017 Category: Consumer Health News Tags: Acid Reflux / GERD Source Type: news

People taking heartburn drugs could have higher risk of death, study claims
Research suggests people on proton pump inhibitors are more likely to die than those taking different antacid or none at allMillions of people taking common heartburn andindigestion medications could be at an increased risk of death, research suggests.The drugs, known as proton pump inhibitors (PPIs), neutralise the acid in the stomach and are widely prescribed, with low doses also available without prescription from pharmacies. In the UK, doctors issue more than 50m prescriptions for PPIs every year.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 4, 2017 Category: Science Authors: James Rudd Tags: Drugs Health Science Society UK news Source Type: news

Proton pump inhibitors associated with raised mortality
Researchers suggest restricting indications for use of PPIs, and treatment duration Related items fromOnMedica Barrett ’s oesophagus (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 4, 2017 Category: UK Health Source Type: news

PPIs Linked With Higher Risk for Death PPIs Linked With Higher Risk for Death
Use and duration of proton-pump inhibitors should be limited to medical indications, researchers say. An expert agrees but says the excess risk is small and the drugs are still often the best option.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 3, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

PPIs Not Found to Raise Risk of Alzheimer ’ s Disease
New research debunks other studies suggesting that PPIs cause mental decline (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - June 29, 2017 Category: Psychiatry Tags: Family Medicine, Geriatrics, Gastroenterology, Internal Medicine, Neurology, Nursing, Pharmacy, Psychiatry, Journal, Source Type: news

Popular Heartburn Meds Don't Raise Alzheimer's Risk: Study
WEDNESDAY, June 28, 2017 -- Drugs used to treat acid reflux and ulcers don't appear to boost the risk of dementia, as has been previously suspected, new research suggests. The study focused on widely used proton pump inhibitors (PPIs) drugs --... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 28, 2017 Category: General Medicine Source Type: news

PPI-responsive Esophageal Eosinophilia: A Valid Diagnosis? PPI-responsive Esophageal Eosinophilia: A Valid Diagnosis?
Is proton pump inhibitor-responsive esophageal eosinophilia just an arbitrary construct, or does it have a distinct molecular and mechanistic basis? Explore the controversy in this article.Current Opinion in Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 28, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

PPIs Linked to Lower Cognitive Decline in Latest Study PPIs Linked to Lower Cognitive Decline in Latest Study
A new observational study has smoothed the waters somewhat over concerns about a possible increased risk for dementia with proton-pump inhibitors.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 22, 2017 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Proton pump inhibitors do not contribute to dementia or Alzheimer's disease
(American Geriatrics Society) Noting that the prescription of proton pump inhibitors is on the rise among middle-aged and older adults, a team of researchers designed a new study to examine PPIs and the risk of dementia, mild cognitive impairment, and Alzheimer's disease. They published their study in the Journal of the American Geriatrics Society. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 22, 2017 Category: International Medicine & Public Health Source Type: news

Your NEJM Group Today: Competency-Based Medical Education / PPIs & Kidney Disease? / Texas Primary Care Opportunities (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Knowledge+ Blog: What is … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 15, 2017 Category: Primary Care Source Type: news

Risk of aspirin-related bleeding is higher in the over-75s
Conclusion This valuable cohort study helps to quantify the extent of bleeding risk in people taking aspirin for secondary prevention of cardiovascular disease. Aspirin is well known to carry bleeding risk – particularly in older adults – but this study suggests the risk may be higher than previously thought. The researchers say that for adults under the age of 75, the annual bleeding risk at around 1% is similar to that suggested by previous trials, as is the ratio of bleeds to the number of cardiovascular events. However, this risk increases for older adults, especially for major bleeds of the stomach and upp...
Source: NHS News Feed - June 14, 2017 Category: Consumer Health News Tags: Medication Older people Source Type: news

Call to co-prescribe PPIs with daily aspirin for older patients
Long-term daily aspirin use is linked to a higher than expected risk of “disabling or fatal” bleeding in adults aged 75 or over, according to researchers in Oxford. (Source: Nursing Times)
Source: Nursing Times - June 14, 2017 Category: Nursing Source Type: news

Proposal: In the Elderly, Add PPIs to Aspirin for Secondary Prevention (FREE)
By Joe Elia Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Proton-pump inhibitors (PPIs) should be added when prescribing antiplatelet therapy after cardiovascular events in the elderly, researchers propose in The Lancet.The researchers followed over 3000 patients for … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 14, 2017 Category: Primary Care Source Type: news

Bleeding risk with long-term aspirin increases substantially with age
GPs should prescribe PPIs to elderly people to cut risk, researchers suggest Related items fromOnMedica Benefits of taking aspirin highest in women aged 65 plus Aspirin boosts cancer immunotherapy, study shows Long-term aspirin use linked to lower risk of gastrointestinal tract cancers Aspirin after mini-stroke reduces risk of major stroke (Source: OnMedica Latest News)
Source: OnMedica Latest News - June 14, 2017 Category: UK Health Source Type: news

PPI Use and Risk of Hip Fracture in Kidney Transplants PPI Use and Risk of Hip Fracture in Kidney Transplants
PPIs are commonly prescribed for kidney transplant recipients -- but might their use be associated with an increased risk of hip fracture among these patients?American Journal of Kidney Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 1, 2017 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

When It Comes to PPIs, Why All the'Mayhem'? When It Comes to PPIs, Why All the'Mayhem'?
With this review of the new literature, Dr David Johnson wants to put the risks associated with proton pump inhibitors into perspective and quiet the noise.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 26, 2017 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

A How-To Guide for Deprescribing PPIs A How-To Guide for Deprescribing PPIs
Dr Arefa Cassoobhoy highlights one of the week's important news stories for primary care.Medscape Internal Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 26, 2017 Category: Consumer Health News Tags: Internal Medicine Commentary Source Type: news

Torax Medical touts preliminary results from Linx GERD study
Johnson & Johnson (NYSE:JNJ) subsidiary Ethicon‘s Torax Medical business today released results from the Caliber trial of its Linx system for treating gastro-esophageal reflux disease, touting quality of life improvements and reduction in reflux levels. The Linx system is an implant composed of interlinked titanium beads with magnetic cores that augments the esophageal sphincter’s barrier function to prevent reflux in patients with gastro-esophageal reflux disease, the company said. Data from the trial was presented at the Digestive Disease Week 2017 meeting in Chicago. The randomized, controlled, 150-patie...
Source: Mass Device - May 24, 2017 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Otolaryngology Ear, Nose & Throat Ethicon Johnson & Johnson Torax Medical Inc. Source Type: news

New Guidelines for Deprescribing Proton Pump Inhibitors New Guidelines for Deprescribing Proton Pump Inhibitors
Clinicians should deprescribe proton pump inhibitors (PPIs) in adults who have completed a minimum 4-week course of PPIs and whose symptoms are resolved, according to new evidence-based guidelines.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 18, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Most Docs Make Wrong Choices in Stopping PPIs (CME/CE)
(MedPage Today) -- Fear of adverse events leads clinicians down an erroneous and dangerous path (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 7, 2017 Category: Gastroenterology Source Type: news

Your NEJM Group Today: Climate Change and Health Interview / PPIs & Stroke / New York Hospitalist Opportunities (FREE)
By the Editors Check out today's selections from NEJM Group: NEJM Audio Interview: Climate Change and Health: Dr. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - April 26, 2017 Category: Primary Care Source Type: news

Gastric Acid Suppression Therapy Ups Risk of Recurrent C. diff Gastric Acid Suppression Therapy Ups Risk of Recurrent C. diff
Withholding proton pump inhibitors (PPIs) or histamine 2 receptor blockers (H2Bs) in the setting of active or recent Clostridium difficile infection may help prevent a recurrent bout of CDI, researchers say.Reuters Health Information (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - March 30, 2017 Category: Infectious Diseases Tags: Gastroenterology News Source Type: news

Proton Pump Inhibitor Use Ups Pneumonia Risk in Dementia
Independent risk factors for pneumonia include age, male gender, underlying cerebrovascular disease (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - March 30, 2017 Category: Respiratory Medicine Tags: Neurology, Pharmacy, Pulmonology, Geriatrics, Journal, Source Type: news

Treating GERD May Reduce Nasal Symptoms Treating GERD May Reduce Nasal Symptoms
In patients with laryngopharyngeal reflux (LPR) and symptoms of sinonasal disease, treatment with a proton pump inhibitor may reduce LPR and nasal symptoms, a new study suggested.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 15, 2017 Category: Allergy & Immunology Tags: Gastroenterology News Source Type: news

Morning Report: PPIs and Kidney Injury, Pain, Depression Screening Morning Report: PPIs and Kidney Injury, Pain, Depression Screening
Dr Arefa Cassoobhoy highlights some of this week's most important medical news: PPIs and CKD, pain as the fifth vital sign, and depression screening in adults.Medscape Internal Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 3, 2017 Category: Consumer Health News Tags: Internal Medicine Commentary Source Type: news

PPIs May Increase Risk for Chronic, Silent Kidney Damage PPIs May Increase Risk for Chronic, Silent Kidney Damage
Most patients who develop chronic kidney disease while taking proton pump inhibitors do not experience acute kidney problems first, a new study showed.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 24, 2017 Category: Gastroenterology Tags: Nephrology News Source Type: news

Heartburn meds linked to risk of kidney damage, study finds
About 15 million Americans take prescription medications known as PPIs for heartburn or acid reflux (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 23, 2017 Category: Consumer Health News Source Type: news

Popular heartburn drugs linked to gradual yet'silent' kidney damage
The sudden onset of kidney problems often serves as a warning for doctors to discontinue patients'use of proton pump inhibitors (PPIs), sold under brand names Prevacid, Prilosec, Nexium and Protonix, among others. But a new study indicates that more than half of patients who develop chronic kidney damage while taking the drugs don't experience acute kidney problems beforehand, according to researchers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 22, 2017 Category: Science Source Type: news

Even Without PPI, Oozing Peptic Ulcers Rarely Rebleed After Endoscopic Hemostasis Even Without PPI, Oozing Peptic Ulcers Rarely Rebleed After Endoscopic Hemostasis
The rebleeding rate of oozing peptic ulcer bleeds (PUB) after successful endoscopic therapy is low, and 72 hours of IV proton pump inhibitor (PPI) does not lower the rate further, according to results of a large multinational randomized trial.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 16, 2017 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Heartburn pills tied to serious bacterial infections
(Reuters Health) - People who take popular heartburn pills known as proton pump inhibitors (PPIs) may be more likely to develop intestinal infections than people who don ’t take these medications, a Scottish study suggests. (Source: Reuters: Health)
Source: Reuters: Health - January 20, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Acid suppression medications linked to serious gastrointestinal infections
In a population-based study from Scotland, use of commonly-prescribed acid suppression medications such as proton pump inhibitors (PPIs) was linked with an increased risk of intestinal infections with C. difficile and Campylobacter bacteria, which can cause considerable illness. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 5, 2017 Category: Science Source Type: news

Indigestion pills taken by millions of Britons could triple stomach bug risk by reducing acid that help fight off the bacteria
A study found those who take proton pump inhibitors, or PPIs, are nearly four times as likely to be struck down by campylobacter – the most common food poisoning bug. (Source: the Mail online | Health)
Source: the Mail online | Health - January 5, 2017 Category: Consumer Health News Source Type: news