Scant Evidence for Proton Pump Inhibitor Role in Gastric Cancer Scant Evidence for Proton Pump Inhibitor Role in Gastric Cancer
Previous studies may not have accounted for the confounding role of the diseases for which the medications are prescribed.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 13, 2023 Category: Cancer & Oncology Tags: Gastroenterology News Source Type: news

PPI Use in Type 2 Diabetes Links With Cardiovascular Events PPI Use in Type 2 Diabetes Links With Cardiovascular Events
Prospective data from almost 20,000 people with type 2 diabetes show that proton pump inhibitor use is linked with significantly more cardiovascular disease events and all-cause death than nonuse.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - January 10, 2023 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

High Rates of Inappropriate PPI Use in Hospitalized Patients High Rates of Inappropriate PPI Use in Hospitalized Patients
More than two fifths of patients discharged with a proton pump inhibitor prescription may have been given it inappropriately, say Israeli researchers who call for action to improve the problem.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - December 7, 2022 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Help! I've had the hiccups for a year! DR MARTIN SCURR answers your health questions 
DR MARTIN SCURR: The standard first-line treatment for chronic hiccups is a four-week trial of a proton pump inhibitor drug, such as omeprazole, to suppress stomach acid secretion. (Source: the Mail online | Health)
Source: the Mail online | Health - November 22, 2022 Category: Consumer Health News Source Type: news

Cost analysis of implementing an exercise program for fall and fracture prevention in older adults on proton pump inhibitor therapy - Wichelmann TA, Dang N, Kruchko DH, AbdulMujeeb S, Ehrenpreis ED.
PURPOSE: Falls have significant financial impact. Proton pump inhibitor (PPI) therapy is associated with an increased risk of falls and fractures. Exercise programs have been shown to decrease risk of falls in the elderly population and are recommended by ... (Source: SafetyLit)
Source: SafetyLit - November 12, 2022 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

IOL Chemicals gets EDQM certification for API supply to Europe
The European Directorate for the Quality of Medicines& HealthCare (EDQM) is a mandatory certification for distribution of any API/ pharma products in Europe. Pantoprazole Sodium Sesquihydrate, an active pharmaceutical ingredient (API), is proton pump inhibitor used in drugs to suppress the gastric acid secretion. "The company started production of Pantoprazole Sodium Sesquihydrate in Q3 FY 2020 at its Punjab-based facility. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 7, 2022 Category: Pharmaceuticals Source Type: news

So what's the best way to treat osteoporosis? DR MARTIN SCURR answers your health questions 
DR MARTIN SCURR: Omeprazole is a type of proton pump inhibitor (PPI), a drug that suppresses stomach acid production. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2022 Category: Consumer Health News Source Type: news

Long-Term Xeljanz for UC; AGA Drops Obesity Drug Guidelines; PPIs & Cystic Fibrosis?
(MedPage Today) -- Health-related quality-of-life outcomes continued to be favorable with maintenance tofacitinib (Xeljanz) for ulcerative colitis (UC) during up to 6 years of follow-up, regardless of treatment history, responder status, or remission... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 20, 2022 Category: Gastroenterology Source Type: news

Vonoprazan Promising for Erosive Esophagitis Vonoprazan Promising for Erosive Esophagitis
The oral potassium-competitive acid blocker vonoprazan was noninferior and superior to the proton pump inhibitor lansoprazole for erosive esophagitis in a phase 3 trial.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 18, 2022 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

'Alarming' Spike in Liver Disease Deaths; Can PPIs Cause Lupus? IBS and Depression
(MedPage Today) -- U.S. deaths from liver disease increased at an "alarming rate" during the COVID-19 pandemic, data from the National Vital Statistic System revealed. (Journal of Hepatology) Analyses of two pharmacovigilance databases confirmed... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - August 19, 2022 Category: Gastroenterology Source Type: news

' Reassuring' Safety Data on PPI Therapy'Reassuring' Safety Data on PPI Therapy
PPIs were generally not associated with an increased risk for mortality due to major causes in a novel analysis accounting for potential protopathic bias.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 19, 2022 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

PPIs Cleared of Death Risk? 'Alarming' Rise in NAFLD; How IBS Became Hot
(MedPage Today) -- Long-term proton pump inhibitor (PPI) use was not linked to a greater all-cause mortality risk after protopathic bias was accounted for. (Gastroenterology) In a randomized trial, an artificial intelligence-powered smartphone... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - July 7, 2022 Category: Gastroenterology Source Type: news

PPIs Should Be Used'Judiciously' in Patients With Cirrhosis PPIs Should Be Used'Judiciously' in Patients With Cirrhosis
Experts call for ' nuanced ' prescribing of proton pump inhibitors to patients with cirrhosis in a study that found lower mortality only in those with gastrointestinal bleeding.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - April 22, 2022 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

PPIs Linked to Better Survival for One Group With Cirrhosis
(MedPage Today) -- Proton pump inhibitors (PPIs), when used for prior gastrointestinal bleeding (GIB), were associated with better survival for veterans with cirrhosis, a retrospective study found. Among more than 76,000 such patients, PPI use... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 11, 2022 Category: Gastroenterology Source Type: news

Deprescribing PPIs: AGA Clinical Practice Update Offers Guidance Deprescribing PPIs: AGA Clinical Practice Update Offers Guidance
Fear of adverse events often drive interest in de-escalating or stopping PPIs, but many fears are unfounded.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - April 8, 2022 Category: Gastroenterology Tags: Gastroenterology News Source Type: news