Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group-
Trends in the incidence and outcomes of sepsis using a Japanese nationwide database were investigated. (Source: Critical Care)
Source: Critical Care - September 16, 2021 Category: Intensive Care Authors: Taro Imaeda, Taka-aki Nakada, Nozomi Takahashi, Yasuo Yamao, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Yutaka Umemura, Asako Matsushima and Kiyohide Fushimi Tags: Research Source Type: research

Concern with reproducibility of rehabilitation after critical illness and hospital discharge
(Source: Critical Care)
Source: Critical Care - September 15, 2021 Category: Intensive Care Authors: Kota Yamauchi, Shunsuke Kina and Shunsuke Taito Tags: Letter Source Type: research

Bedside estimates of dead space using end-tidal CO2 are independently associated with mortality in ARDS
In acute respiratory distress syndrome (ARDS), dead space fraction has been independently associated with mortality. We hypothesized that early measurement of the difference between arterial and end-tidal CO2 (ar... (Source: Critical Care)
Source: Critical Care - September 15, 2021 Category: Intensive Care Authors: Paola Lecompte-Osorio, Steven D. Pearson, Cole H. Pieroni, Matthew R. Stutz, Anne S. Pohlman, Julie Lin, Jesse B. Hall, Yu M. Htwe, Patrick G. Belvitch, Steven M. Dudek, Krysta Wolfe, Bhakti K. Patel and John P. Kress Tags: Research Source Type: research

Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression
Delirium is a clinical syndrome occurring in heterogeneous patient populations. It affects 45 –87% of critical care patients and is often associated with adverse outcomes including acquired dementia, institutio... (Source: Critical Care)
Source: Critical Care - September 15, 2021 Category: Intensive Care Authors: Emily M. L. Bowman, Emma L. Cunningham, Valerie J. Page and Daniel F. McAuley Tags: Review Source Type: research

Antifungal prophylaxis for prevention of COVID-19-associated pulmonary aspergillosis in critically ill patients: an observational study
Coronavirus disease 19 (COVID-19)-associated pulmonary aspergillosis (CAPA) emerged as important fungal complications in patients with COVID-19-associated severe acute respiratory failure (ARF). Whether mould ... (Source: Critical Care)
Source: Critical Care - September 15, 2021 Category: Intensive Care Authors: Stefan Hatzl, Alexander C. Reisinger, Florian Posch, Juergen Prattes, Martin Stradner, Stefan Pilz, Philipp Eller, Michael Schoerghuber, Wolfgang Toller, Gregor Gorkiewicz, Philipp Metnitz, Martin Rief, Florian Pr üller, Alexander R. Rosenkranz, Thomas V Tags: Research Source Type: research

Identification of persistent and resolving subphenotypes of acute hypoxemic respiratory failure in two independent cohorts
Acute hypoxemic respiratory failure (HRF) is associated with high morbidity and mortality, but its heterogeneity challenges the identification of effective therapies. Defining subphenotypes with distinct progn... (Source: Critical Care)
Source: Critical Care - September 15, 2021 Category: Intensive Care Authors: Neha A. Sathe, Leila R. Zelnick, Carmen Mikacenic, Eric D. Morrell, Pavan K. Bhatraju, J. Brennan McNeil, Susanna Kosamo, Catherine L. Hough, W. Conrad Liles, Lorraine B. Ware and Mark M. Wurfel Tags: Research Source Type: research

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients
Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first thr... (Source: Critical Care)
Source: Critical Care - September 13, 2021 Category: Intensive Care Authors: Antoni Torres, Anna Motos, Jordi Riera, Laia Fern ández-Barat, Adrián Ceccato, Raquel Pérez-Arnal, Dario García-Gasulla, Oscar Peñuelas, José Angel Lorente, Alejandro Rodriguez, David de Gonzalo-Calvo, Raquel Almansa, Albert Gabarrús, Rosario Mené Tags: Research Source Type: research

Between-centre differences in care for in-hospital cardiac arrest: a prospective cohort study
This study aims to evaluate care for patients suffering in-hospital cardiac... (Source: Critical Care)
Source: Critical Care - September 10, 2021 Category: Intensive Care Authors: B. Y. Gravesteijn, M. Schluep, H. F. Lingsma, R. J. Stolker, H. Endeman and S. E. Hoeks Tags: Research Source Type: research

The management of multi-morbidity in elderly patients: Ready yet for precision medicine in intensive care?
There is ongoing demographic ageing and increasing longevity of the population, with previously devastating and often-fatal diseases now transformed into chronic conditions. This is turning multi-morbidity int... (Source: Critical Care)
Source: Critical Care - September 10, 2021 Category: Intensive Care Authors: Michael Beil, Hans Flaatten, Bertrand Guidet, Sigal Sviri, Christian Jung, Dylan de Lange, Susannah Leaver, Jesper Fj ølner, Wojciech Szczeklik and Peter Vernon van Heerden Tags: Viewpoint Source Type: research

The use of head helmets to deliver noninvasive ventilatory support: a comprehensive review of technical aspects and clinical findings
A helmet, comprising a transparent hood and a soft collar, surrounding the patient ’s head can be used to deliver noninvasive ventilatory support, both as continuous positive airway pressure and noninvasive po... (Source: Critical Care)
Source: Critical Care - September 8, 2021 Category: Intensive Care Authors: Andrea Coppadoro, Elisabetta Zago, Fabio Pavan, Giuseppe Foti and Giacomo Bellani Tags: Review Source Type: research

Machine-learning-based COVID-19 mortality prediction model and identification of patients at low and high risk of dying
The coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-Cov2 virus has become the greatest health and controversial issue for worldwide nations. It is associated with different clinical manifestati... (Source: Critical Care)
Source: Critical Care - September 8, 2021 Category: Intensive Care Authors: Mohammad M. Banoei, Roshan Dinparastisaleh, Ali Vaeli Zadeh and Mehdi Mirsaeidi Tags: Research Source Type: research

Isn ’t it time to abandon ARDS? The COVID-19 lesson
(Source: Critical Care)
Source: Critical Care - September 6, 2021 Category: Intensive Care Authors: L. Gattinoni and J. J. Marini Tags: Commentary Source Type: research

Seasonal trends of incidence and outcomes of cardiogenic shock : findings from a large, nationwide inpatients sample with 441,696 cases
(Source: Critical Care)
Source: Critical Care - September 6, 2021 Category: Intensive Care Authors: Peter Moritz Becher, Benedikt Schrage, Alina Go ßling, Nina Fluschnik, Moritz Seiffert, Alexander M. Bernhardt, Hermann Reichenspurner, Paulus Kirchhof, Stefan Blankenberg and Dirk Westermann Tags: Research Letter Source Type: research

Ten strategies to optimize early mobilization and rehabilitation in intensive care
(Source: Critical Care)
Source: Critical Care - September 3, 2021 Category: Intensive Care Authors: Carol L. Hodgson, Stefan J. Schaller, Peter Nydahl, Karina Tavares Timenetsky and Dale M. Needham Tags: Commentary Source Type: research

Selective digestive decontamination, a seemingly effective regimen with individual benefit or a flawed concept with population harm?
Selective digestive decontamination (SDD) regimens, variously constituted with topical antibiotic prophylaxis (TAP) and protocolized parenteral antibiotic prophylaxis (PPAP), appear highly effective for preven... (Source: Critical Care)
Source: Critical Care - September 1, 2021 Category: Intensive Care Authors: James C. Hurley Tags: Viewpoint Source Type: research