Accuracy of respiratory muscle assessments to predict weaning outcomes: a systematic review and comparative meta-analysis
Several bedside assessments are used to evaluate respiratory muscle function and to predict weaning from mechanical ventilation in patients on the intensive care unit. It remains unclear which assessments perf... (Source: Critical Care)
Source: Critical Care - March 7, 2024 Category: Intensive Care Authors: Diego Poddighe, Marine Van Hollebeke, Yasir Qaiser Choudhary, D ébora Ribeiro Campos, Michele R. Schaeffer, Jan Y. Verbakel, Greet Hermans, Rik Gosselink and Daniel Langer Tags: Research Source Type: research
Pathophysiology of acute lung injury in patients with acute brain injury: the triple-hit hypothesis
It has been convincingly demonstrated in recent years that isolated acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and systems. Of all potential target organs and syste... (Source: Critical Care)
Source: Critical Care - March 7, 2024 Category: Intensive Care Authors: Mairi Ziaka and Aristomenis Exadaktylos Tags: Review Source Type: research
Toxicities, intensive care management, and outcome of chimeric antigen receptor T cells in adults: an update
Chimeric antigen receptor T cells are a promising new immunotherapy for haematological malignancies. Six CAR-T cells products are currently available for adult patients with refractory or relapsed high-grade B... (Source: Critical Care)
Source: Critical Care - March 5, 2024 Category: Intensive Care Authors: Mathieu Bellal, Jolan Malherbe, Gandhi Damaj and Damien Du Cheyron Tags: Review Source Type: research
The acute mesenteric ischaemia (AMESI) study: a matter of incidence
(Source: Critical Care)
Source: Critical Care - March 4, 2024 Category: Intensive Care Authors: Lorenzo Garzelli and Mathieu Nacher Tags: Matters Arising Source Type: research
Impact of hyperoxia on the gut during critical illnesses
Molecular oxygen is typically delivered to patients via oxygen inhalation or extracorporeal membrane oxygenation (ECMO), potentially resulting in systemic hyperoxia from liberal oxygen inhalation or localized ... (Source: Critical Care)
Source: Critical Care - March 1, 2024 Category: Intensive Care Authors: Ninan Dai, Juan Gu, Yanhong Luo, Yuanfa Tao, Yuehting Chou, Ying He, Han Qin, Tao Chen, Xiaoyun Fu, Miao Chen and Zhouxiong Xing Tags: Review Source Type: research
Imatinib treatment improves hyperglycaemic dysregulation in severe COVID-19: a secondary analysis of blood biomarkers in a randomised controlled trial
SARS-CoV-2 can induce insulin resistance, which is, among others, mediated by adipose tissue dysfunction and reduced angiotensin-converting enzyme 2 (ACE2) enzymatic activity. In SARS-CoV-2-infected mice, the ... (Source: Critical Care)
Source: Critical Care - February 29, 2024 Category: Intensive Care Authors: Erik Duijvelaar, Xiaoke Pan, Harm Jan Bogaard, Etto C. Eringa and Jurjan Aman Tags: Brief Report Source Type: research
Prevention of post-operative delirium using an overnight infusion of dexmedetomidine in patients undergoing cardiac surgery: a pragmatic, randomized, double-blind, placebo-controlled trial
After cardiac surgery, post-operative delirium (PoD) is acknowledged to have a significant negative impact on patient outcome. To date, there is no valuable and specific treatment for PoD. Critically ill patie... (Source: Critical Care)
Source: Critical Care - February 29, 2024 Category: Intensive Care Authors: Olivier Huet, Thomas Gargadennec, Jean-Ferr éol Oilleau, Bertrand Rozec, Nicolas Nesseler, Adrien Bouglé, Thomas Kerforne, Sigismond Lasocki, Vedat Eljezi, Géraldine Dessertaine, Julien Amour and Xavier Chapalain Tags: Research Source Type: research
The use of mechanical CPR for IHCA during the COVID-19 pandemic as compared to the pre-pandemic period
(Source: Critical Care)
Source: Critical Care - February 27, 2024 Category: Intensive Care Authors: Conor Crowley, Justin Salciccioli, Yuxiu Lei, Christopher Hansen, Tomoyoshi Tamura, Edy Y. Kim and Ari Moskowitz Tags: Correspondence Source Type: research
Using a targeted metabolomics approach to explore differences in ARDS associated with COVID-19 compared to ARDS caused by H1N1 influenza and bacterial pneumonia
Acute respiratory distress syndrome (ARDS) is a life-threatening critical care syndrome commonly associated with infections such as COVID-19, influenza, and bacterial pneumonia. Ongoing research aims to improv... (Source: Critical Care)
Source: Critical Care - February 27, 2024 Category: Intensive Care Authors: Chel Hee Lee, Mohammad M. Banoei, Mariam Ansari, Matthew P. Cheng, Francois Lamontagne, Donald Griesdale, David E. Lasry, Koray Demir, Vinay Dhingra, Karen C. Tran, Terry Lee, Kevin Burns, David Sweet, John Marshall, Arthur Slutsky, Srinivas Murthy & hell Tags: Research Source Type: research
Violence against healthcare professionals in intensive care units: a systematic review and meta-analysis of frequency, risk factors, interventions, and preventive measures
To assess the frequency, risk factors, consequences, and prevention of violence against healthcare workers in intensive care units. (Source: Critical Care)
Source: Critical Care - February 26, 2024 Category: Intensive Care Authors: Sebastian Berger, Pascale Grzonka, Anja I. Frei, Sabina Hunziker, Sira M. Baumann, Simon A. Amacher, Caroline E. Gebhard and Raoul Sutter Tags: Research Source Type: research
Reflections on epidemiological investigations of sepsis in the Asian Region
(Source: Critical Care)
Source: Critical Care - February 26, 2024 Category: Intensive Care Authors: Mingqiang Wang and Lin Zhong Tags: Matters Arising Source Type: research
How often do we need to update PEEP setting during prone positioning in ARDS?
(Source: Critical Care)
Source: Critical Care - February 26, 2024 Category: Intensive Care Authors: Ling Sang, Zhimin Lin and Zhanqi Zhao Tags: Correspondence Source Type: research
Improving management of ARDS: uniting acute management and long-term recovery
Acute Respiratory Distress Syndrome (ARDS) is an important global health issue with high in-hospital mortality. Importantly, the impact of ARDS extends beyond the acute phase, with increased mortality and disa... (Source: Critical Care)
Source: Critical Care - February 23, 2024 Category: Intensive Care Authors: Nicola Latronico, M. Eikermann, E. W. Ely and D. M. Needham Tags: Perspective Source Type: research
Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial
Despite evidence associating inflammatory biomarkers with worse outcomes in hospitalized adults with COVID-19, trials of immunomodulatory therapies have met with mixed results, likely due in part to biological... (Source: Critical Care)
Source: Critical Care - February 21, 2024 Category: Intensive Care Authors: Narges Alipanah-Lechner, James Hurst-Hopf, Kevin Delucchi, Lamorna Swigart, Andrew Willmore, Benjamin LaCombe, Robin Dewar, H. Clifford Lane, Perrine Lallemand, Kathleen D. Liu, Laura Esserman, Michael A. Matthay and Carolyn S. Calfee Tags: Research Source Type: research
Extracorporeal cardiopulmonary resuscitation versus conventional CPR in cardiac arrest: an updated meta-analysis and trial sequential analysis
Extracorporeal cardiopulmonary resuscitation (ECPR) may reduce mortality and improve neurological outcomes in patients with cardiac arrest. We updated our existing meta-analysis and trial sequential analysis t... (Source: Critical Care)
Source: Critical Care - February 21, 2024 Category: Intensive Care Authors: Christopher Jer Wei Low, Ryan Ruiyang Ling, Kollengode Ramanathan, Ying Chen, Bram Rochwerg, Tetsuhisa Kitamura, Taku Iwami, Marcus Eng Hock Ong and Yohei Okada Tags: Brief Report Source Type: research
