Prognosis of patients excluded by the definition of septic shock based on their lactate levels after initial fluid resuscitation: a prospective multi-center observational study
Septic shock can be defined both by the presence of hyperlactatemia and need of vasopressors. Lactate levels should be measured after volume resuscitation (as per the Sepsis-3 definition). However, currently, ... (Source: Critical Care)
Source: Critical Care - February 24, 2018 Category: Intensive Care Authors: Byuk Sung Ko, Kyuseok Kim, Sung-Hyuk Choi, Gu Hyun Kang, Tae Gun Shin, You Hwan Jo, Seung Mok Ryoo, Jin Ho Beom, Woon Yong Kwon, Kap Su Han, Han Sung Choi, Sung Phil Chung, Gil Joon Suh, Tae Ho Lim and Won Young Kim Tags: Research Source Type: research

Detection of inspiratory recruitment of atelectasis by automated lung sound analysis as compared to four-dimensional computed tomography in a porcine lung injury model
This study... (Source: Critical Care)
Source: Critical Care - February 24, 2018 Category: Intensive Care Authors: Stefan Boehme, Fr édéric P. R. Toemboel, Erik K. Hartmann, Alexander H. Bentley, Oliver Weinheimer, Yang Yang, Tobias Achenbach, Michael Hagmann, Eugenijus Kaniusas, James E. Baumgardner and Klaus Markstaller Tags: Research Source Type: research

Artificial oxygen carriers: a new future?
(Source: Critical Care)
Source: Critical Care - February 23, 2018 Category: Intensive Care Authors: Donat R. Spahn Tags: Editorial Source Type: research

Should we measure the central venous pressure to guide fluid management? Ten answers to 10 questions
The central venous pressure (CVP) is the most frequently used variable to guide fluid resuscitation in critically ill patients, although its use has been challenged. In this viewpoint, we use a question and an... (Source: Critical Care)
Source: Critical Care - February 23, 2018 Category: Intensive Care Authors: Daniel De Backer and Jean-Louis Vincent Tags: Viewpoint Source Type: research

What is new in critical care echocardiography?
(Source: Critical Care)
Source: Critical Care - February 22, 2018 Category: Intensive Care Authors: Philippe Vignon Tags: Editorial Source Type: research

Earplugs in the ICU: To sleep, to dream
(Source: Critical Care)
Source: Critical Care - February 22, 2018 Category: Intensive Care Authors: Edward Litton, Rosalind Elliott and Kelly Thompson Tags: Letter Source Type: research

Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review
Hemodynamic instability related to renal replacement therapy (HIRRT) may increase the risk of death and limit renal recovery. Studies in end-stage renal disease populations on maintenance hemodialysis suggest ... (Source: Critical Care)
Source: Critical Care - February 22, 2018 Category: Intensive Care Authors: Adrianna Douvris, Gurpreet Malhi, Swapnil Hiremath, Lauralyn McIntyre, Samuel A. Silver, Sean M. Bagshaw, Ron Wald, Claudio Ronco, Lindsey Sikora, Catherine Weber and Edward G. Clark Tags: Research Source Type: research

Protracted immune disorders at one year after ICU discharge in patients with septic shock
Sepsis is a leading cause of mortality and critical illness worldwide and is associated with an increased mortality rate in the months following hospital discharge. The occurrence of persistent or new organ dy... (Source: Critical Care)
Source: Critical Care - February 21, 2018 Category: Intensive Care Authors: Florence Rich é, Benjamin G. Chousterman, Patrice Valleur, Alexandre Mebazaa, Jean-Marie Launay and Etienne Gayat Tags: Research Source Type: research

Leukocyte telomere length in paediatric critical illness: effect of early parenteral nutrition
Children who have suffered from critical illnesses that required treatment in a paediatric intensive care unit (PICU) have long-term physical and neurodevelopmental impairments. The mechanisms underlying this ... (Source: Critical Care)
Source: Critical Care - February 21, 2018 Category: Intensive Care Authors: S ören Verstraete, Ilse Vanhorebeek, Esther van Puffelen, Inge Derese, Catherine Ingels, Sascha C. Verbruggen, Pieter J. Wouters, Koen F. Joosten, Jan Hanot, Gonzalo G. Guerra, Dirk Vlasselaers, Jue Lin and Greet Van den Berghe Tags: Research Source Type: research

The practice of intensive care in Latin America: a survey of academic intensivists
Intensive care medicine is a relatively young discipline that has rapidly grown into a full-fledged medical subspecialty. Intensivists are responsible for managing an ever-increasing number of patients with co... (Source: Critical Care)
Source: Critical Care - February 21, 2018 Category: Intensive Care Authors: Ricardo Castro, Nicolas Nin, Fernando R íos, Leyla Alegría, Elisa Estenssoro, Gastón Murias, Gilberto Friedman, Manuel Jibaja, Gustavo Ospina-Tascon, Javier Hurtado, María del Carmen Marín, Flavia R. Machado, Alexandre Biasi Cavalcanti, Arnaldo Dubin Tags: Research Source Type: research

Hypertonic saline infusion for treating intracranial hypertension after severe traumatic brain injury
Traumatic brain injury (TBI) remains a major cause of mortality and disability. Post-traumatic intracranial hypertension (ICH) further complicates the care of patients. Hyperosmolar agents are recommended for ... (Source: Critical Care)
Source: Critical Care - February 20, 2018 Category: Intensive Care Authors: Halinder S. Mangat Tags: Editorial Source Type: research

Transcranial Doppler combined with quantitative EEG brain function monitoring and outcome prediction in patients with severe acute intracerebral hemorrhage
Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related to increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcrania... (Source: Critical Care)
Source: Critical Care - February 20, 2018 Category: Intensive Care Authors: Ying Chen, Weihai Xu, Lijuan Wang, Xiaoming Yin, Jie Cao, Fang Deng, Yingqi Xing and Jiachun Feng Tags: Research Source Type: research

Animal-assisted intervention in the ICU: a tool for humanization
(Source: Critical Care)
Source: Critical Care - February 12, 2018 Category: Intensive Care Authors: Megan M. Hosey, Janice Jaskulski, Stephen T. Wegener, Linda L. Chlan and Dale M. Needham Tags: Editorial Source Type: research

Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia - the “Co-MED study”
Hypernatraemia is common in inpatients and is associated with substantial morbidity. Its differential diagnosis is challenging, and delayed treatment may have devastating consequences. The most important hormo... (Source: Critical Care)
Source: Critical Care - February 9, 2018 Category: Intensive Care Authors: Nicole Nigro, Bettina Winzeler, Isabelle Suter-Widmer, Philipp Schuetz, Birsen Arici, Martina Bally, Julie Refardt, Matthias Betz, Gani Gashi, Sandrine A. Urwyler, Lukas Burget, Claudine A. Blum, Andreas Bock, Andreas Huber, Beat M üller and Mirjam Chris Tags: Research Source Type: research

Prevalence and outcome of patients with non-ST segment elevation myocardial infarction with occluded “culprit” artery – a systemic review and meta-analysis
The aim was to determine the prevalence and impact of an occluded “culprit” artery (OCA) in patients with non-ST segment elevation myocardial infarction (NSTEMI). (Source: Critical Care)
Source: Critical Care - February 9, 2018 Category: Intensive Care Authors: Chi-Sheng Hung, Ying-Hsien Chen, Ching-Chang Huang, Mao-Shin Lin, Chih-Fan Yeh, Hung-Yuan Li and Hsien-Li Kao Tags: Research Source Type: research

End-expiratory occlusion maneuver to predict fluid responsiveness in the intensive care unit: an echocardiographic study
In mechanically ventilated patients, an increase in cardiac index during an end-expiratory-occlusion test predicts fluid responsiveness. To identify this rapid increase in cardiac index, continuous and instant... (Source: Critical Care)
Source: Critical Care - February 8, 2018 Category: Intensive Care Authors: Delphine Georges, Hugues de Courson, Romain Lanchon, Musa Sesay, Karine Nouette-Gaulain and Matthieu Biais Tags: Research Source Type: research

Trustworthy or flawed clinical prediction rule?
(Source: Critical Care)
Source: Critical Care - February 8, 2018 Category: Intensive Care Authors: Anders Granholm, Anders Perner, Aksel Karl Georg Jensen and Morten Hylander M øller Tags: Letter Source Type: research

Cardiac output monitoring: throw it out … or keep it?
(Source: Critical Care)
Source: Critical Care - February 8, 2018 Category: Intensive Care Authors: Xavier Monnet and Jean-Louis Teboul Tags: Commentary Source Type: research

Pre-hospital transthoracic echocardiography for early identification of non-ST-elevation myocardial infarction in patients with acute coronary syndrome
Non-ST elevation myocardial infarction (NSTEMI) is a common manifestation of acute coronary syndrome (ACS), but delayed diagnosis can increase mortality. In this proof of principle study, the emergency physici... (Source: Critical Care)
Source: Critical Care - February 7, 2018 Category: Intensive Care Authors: Ingo Bergmann, Benedikt B üttner, Elena Teut, Claudius Jacobshagen, José Hinz, Michael Quintel, Ashham Mansur and Markus Roessler Tags: Research Source Type: research

Comparing fiberoptic bronchoscopy- and a tracheal tube-mounted camera-guided percutaneous dilatational tracheostomy
(Source: Critical Care)
Source: Critical Care - February 7, 2018 Category: Intensive Care Authors: Fu-Shan Xue, Chao Wen and Ya-Yang Liu Tags: Letter Source Type: research

To eat or to breathe? The answer is both! Nutritional management during noninvasive ventilation
Treating respiratory distress is a priority when managing critically ill patients. Non-invasive ventilation (NIV) is increasingly used as a tool to prevent endotracheal intubation. Providing oral or enteral nu... (Source: Critical Care)
Source: Critical Care - February 6, 2018 Category: Intensive Care Authors: Pierre Singer and Sornwichate Rattanachaiwong Tags: Editorial Source Type: research

Performance of the quick Sequential (sepsis-related) Organ Failure Assessment score as a prognostic tool in infected patients outside the intensive care unit: a systematic review and meta-analysis
The usefulness of the quick Sequential (Sepsis-related) Organ Failure Assessment (qSOFA) score in providing bedside criteria for early prediction of poor outcomes in patients with suspected infection remains c... (Source: Critical Care)
Source: Critical Care - February 6, 2018 Category: Intensive Care Authors: Jae-Uk Song, Cheol Kyung Sin, Hye Kyeong Park, Sung Ryul Shim and Jonghoo Lee Tags: Research Source Type: research

Variation of poorly ventilated lung units (silent spaces) measured by electrical impedance tomography to dynamically assess recruitment
Assessing alveolar recruitment at different positive end-expiratory pressure (PEEP) levels is a major clinical and research interest because protective ventilation implies opening the lung without inducing ove... (Source: Critical Care)
Source: Critical Care - January 31, 2018 Category: Intensive Care Authors: Savino Spadaro, Tommaso Mauri, Stephan H. B öhm, Gaetano Scaramuzzo, Cecilia Turrini, Andreas D. Waldmann, Riccardo Ragazzi, Antonio Pesenti and Carlo Alberto Volta Tags: Research Source Type: research

Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study
The aim of the study was to describe the population pharmacokinetics (PK) of meropenem in critically ill patients receiving sustained low-efficiency dialysis (SLED). (Source: Critical Care)
Source: Critical Care - January 30, 2018 Category: Intensive Care Authors: Stephan Braune, Christina K önig, Jason A. Roberts, Axel Nierhaus, Oliver Steinmetz, Michael Baehr, Stefan Kluge and Claudia Langebrake Tags: Research Source Type: research

Breaking the rules: is it the neurointensivists ’ turn?
(Source: Critical Care)
Source: Critical Care - January 29, 2018 Category: Intensive Care Authors: Paolo Gritti, Oluwaseun Akeju, Ferdinando Luca Lorini, Andrea Lanterna, Carlo Brembilla and Federico Bilotta Tags: Letter Source Type: research

Doctor —your septic patients have scurvy!
(Source: Critical Care)
Source: Critical Care - January 29, 2018 Category: Intensive Care Authors: Paul E. Marik and Michael H. Hooper Tags: Editorial Source Type: research

Back-to-back comparison of penKID with NephroCheck ® to predict acute kidney injury at admission in intensive care unit: a brief report
(Source: Critical Care)
Source: Critical Care - January 29, 2018 Category: Intensive Care Authors: Etienne Gayat, Cyril Touchard, Alexa Hollinger, Antoine Vieillard-Baron, Alexandre Mebazaa and Matthieu Legrand Tags: Letter Source Type: research

Transfers from intensive care unit to hospital ward: a multicentre textual analysis of physician progress notes
Little is known about documentation during transitions of patient care between clinical specialties. Therefore, we examined the focus, structure and purpose of physician progress notes for patients transferred... (Source: Critical Care)
Source: Critical Care - January 28, 2018 Category: Intensive Care Authors: Kyla N. Brown, Jeanna Parsons Leigh, Hasham Kamran, Sean M. Bagshaw, Rob A. Fowler, Peter M. Dodek, Alexis F. Turgeon, Alan J. Forster, Francois Lamontagne, Andrea Soo and Henry T. Stelfox Tags: Research Source Type: research

Stress ulcer prophylaxis in intensive care unit patients receiving enteral nutrition: a systematic review and meta-analysis
Pharmacologic stress ulcer prophylaxis (SUP) is recommended in critically ill patients with high risk of stress-related gastrointestinal (GI) bleeding. However, as to patients receiving enteral feeding, the pr... (Source: Critical Care)
Source: Critical Care - January 28, 2018 Category: Intensive Care Authors: Hui-Bin Huang, Wei Jiang, Chun-Yao Wang, Han-Yu Qin and Bin Du Tags: Research Source Type: research

Do we need new trials of procalcitonin-guided antibiotic therapy?
Using biomarkers as a guide to tailor the duration of antibiotic treatment in respiratory infections is an attractive hypothesis assessed in several studies. Recent work aiming to summarize the evidence assess... (Source: Critical Care)
Source: Critical Care - January 27, 2018 Category: Intensive Care Authors: Thiago Lisboa, Jorge Salluh and Pedro Povoa Tags: Commentary Source Type: research

Performance of critical care prognostic scoring systems in low and middle-income countries: a systematic review
Prognostic models —used in critical care medicine for mortality predictions, for benchmarking and for illness stratification in clinical trials—have been validated predominantly in high-income countries. These ... (Source: Critical Care)
Source: Critical Care - January 26, 2018 Category: Intensive Care Authors: Rashan Haniffa, Ilhaam Isaam, A. Pubudu De Silva, Arjen M. Dondorp and Nicolette F. De Keizer Tags: Research Source Type: research

Cerebral metabolic effects of strict versus conventional glycaemic targets following severe traumatic brain injury
Optimal glycaemic targets for patients with severe traumatic brain injury remain unclear. The primary objective of this microdialysis study was to compare cerebral metabolism with strict versus conventional gl... (Source: Critical Care)
Source: Critical Care - January 25, 2018 Category: Intensive Care Authors: Mark P. Plummer, Natalia Notkina, Ivan Timofeev, Peter J. Hutchinson, Mark E. Finnis and Arun K. Gupta Tags: Research Source Type: research

Perioperative fluid management in kidney transplantation: a black box
The incidence of delayed graft function in patients undergoing kidney transplantation remains significant. Optimal fluid therapy has been shown to decrease delayed graft function after renal transplantation. T... (Source: Critical Care)
Source: Critical Care - January 25, 2018 Category: Intensive Care Authors: Maria Helena Calixto Fernandes, Thomas Schricker, Sheldon Magder and Roupen Hatzakorzian Tags: Review Source Type: research

Serum suPAR and syndecan-4 levels predict severity of community-acquired pneumonia: a prospective, multi-centre study
Community-acquired pneumonia (CAP) is a major cause of death worldwide and occurs with variable severity. There are few studies focused on the expression of soluble urokinase-type plasminogen activator recepto... (Source: Critical Care)
Source: Critical Care - January 24, 2018 Category: Intensive Care Authors: Qiongzhen Luo, Pu Ning, Yali Zheng, Ying Shang, Bing Zhou and Zhancheng Gao Tags: Research Source Type: research

An attenuated rate of leg muscle protein depletion and leg free amino acid efflux over time is seen in ICU long-stayers
There is extensive documentation on skeletal muscle protein depletion during the initial phase of critical illness. However, for intensive care unit (ICU) long-stayers, objective data are very limited. In this... (Source: Critical Care)
Source: Critical Care - January 23, 2018 Category: Intensive Care Authors: Lena Gamrin-Gripenberg, Martin Sundstr öm-Rehal, Daniel Olsson, Jonathan Grip, Jan Wernerman and Olav Rooyackers Tags: Research Source Type: research

Supplemental parenteral nutrition versus usual care in critically ill adults: a pilot randomized controlled study
In the critically ill, energy delivery from enteral nutrition (EN) is often less than the estimated energy requirement. Parenteral nutrition (PN) as a supplement to EN may increase energy delivery. We aimed to... (Source: Critical Care)
Source: Critical Care - January 23, 2018 Category: Intensive Care Authors: Emma J. Ridley, Andrew R. Davies, Rachael Parke, Michael Bailey, Colin McArthur, Lyn Gillanders, D. James Cooper and Shay McGuinness Tags: Research Source Type: research

Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials
We performed a systematic review of randomized controlled studies evaluating any drug, technique or device aimed at improving the success rate or safety of tracheal intubation in the critically ill. (Source: Critical Care)
Source: Critical Care - January 20, 2018 Category: Intensive Care Authors: Luca Cabrini, Giovanni Landoni, Martina Baiardo Radaelli, Omar Saleh, Carmine D. Votta, Evgeny Fominskiy, Alessandro Putzu, C ézar Daniel Snak de Souza, Massimo Antonelli, Rinaldo Bellomo, Paolo Pelosi and Alberto Zangrillo Tags: Research Source Type: research

The apelinergic system as an alternative to catecholamines in low-output septic shock
Catecholamines, in concert with fluid resuscitation, have long been recommended in the management of septic shock. However, not all patients respond positively and controversy surrounding the efficacy-to-safet... (Source: Critical Care)
Source: Critical Care - January 19, 2018 Category: Intensive Care Authors: David Coquerel, Xavier Sainsily, Lauralyne Dumont, Philippe Sarret, Éric Marsault, Mannix Auger-Messier and Olivier Lesur Tags: Viewpoint Source Type: research

Glycaemic control targets after traumatic brain injury: a systematic review and meta-analysis
Optimal glycaemic targets in traumatic brain injury (TBI) remain unclear. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs) comparing intensive with conventional glycaem... (Source: Critical Care)
Source: Critical Care - January 19, 2018 Category: Intensive Care Authors: Jeroen Hermanides, Mark P. Plummer, Mark Finnis, Adam M. Deane, Jonathan P. Coles and David K. Menon Tags: Research Source Type: research

Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: a cohort study
Providing supplemental oxygen is fundamental in the management of mechanically ventilated patients. Increasing amounts of data show worse clinical outcomes associated with hyperoxia. However, these previous da... (Source: Critical Care)
Source: Critical Care - January 18, 2018 Category: Intensive Care Authors: David Page, Enyo Ablordeppey, Brian T. Wessman, Nicholas M. Mohr, Stephen Trzeciak, Marin H. Kollef, Brian W. Roberts and Brian M. Fuller Tags: Research Source Type: research

Determinants of long-term outcome in ICU survivors: results from the FROG-ICU study
Intensive care unit (ICU) survivors have reduced long-term survival compared to the general population. Identifying parameters at ICU discharge that are associated with poor long-term outcomes may prove useful... (Source: Critical Care)
Source: Critical Care - January 18, 2018 Category: Intensive Care Authors: Etienne Gayat, Alain Cariou, Nicolas Deye, Antoine Vieillard-Baron, Samir Jaber, Charles Damoisel, Qin Lu, Xavier Monnet, Isabelle Rennuit, Elie Azoulay, Marc L éone, Heikel Oueslati, Bertrand Guidet, Diane Friedman, Antoine Tesnière, Romain Sonneville Tags: Research Source Type: research

Global trends in the awareness of sepsis: insights from search engine data between 2012 and 2017
Sepsis is an established global health priority with high mortality that can be curtailed through early recognition and intervention; as such, efforts to raise awareness are potentially impactful and increasin... (Source: Critical Care)
Source: Critical Care - January 17, 2018 Category: Intensive Care Authors: Craig S. Jabaley, James M. Blum, Robert F. Groff and Vikas N. O ’Reilly-Shah Tags: Research Source Type: research

Incidence, risk factors and impact of protocolised care on exposure keratopathy in critically ill adults: a two-phase prospective cohort study
Exposure keratopathy (EK) has a high incidence in critically ill patients. We aimed to determine the rate of EK in patients admitted to our intensive care unit (ICU), identify risk factors for developing EK an... (Source: Critical Care)
Source: Critical Care - January 16, 2018 Category: Intensive Care Authors: Obaid Kousha, Zubaid Kousha and Jonathan Paddle Tags: Research Source Type: research

Cost-effectiveness study of early versus late parenteral nutrition in critically ill children (PEPaNIC): preplanned secondary analysis of a multicentre randomised controlled trial
The multicentre randomised controlled PEPaNIC trial showed that withholding parenteral nutrition (PN) during the first week of critical illness in children was clinically superior to providing early PN. This s... (Source: Critical Care)
Source: Critical Care - January 15, 2018 Category: Intensive Care Authors: Esther van Puffelen, Suzanne Polinder, Ilse Vanhorebeek, Pieter Jozef Wouters, Niek Bossche, Guido Peers, S ören Verstraete, Koen Felix Maria Joosten, Greet Van den Berghe, Sascha Cornelis Antonius Theodorus Verbruggen and Dieter Mesotten Tags: Research Source Type: research

High frequency percussive ventilation increases alveolar recruitment in early acute respiratory distress syndrome: an experimental, physiological and CT scan study
High frequency percussive ventilation (HFPV) combines diffusive (high frequency mini-bursts) and convective ventilation patterns. Benefits include enhanced oxygenation and hemodynamics, and alveolar recruitmen... (Source: Critical Care)
Source: Critical Care - January 11, 2018 Category: Intensive Care Authors: Thomas Godet, Matthieu Jabaudon, Ra ïko Blondonnet, Aymeric Tremblay, Jules Audard, Benjamin Rieu, Bruno Pereira, Jean-Marc Garcier, Emmanuel Futier and Jean-Michel Constantin Tags: Research Source Type: research

Developing a feasible and valid scoring system for critically ill patients in resource-limited settings
(Source: Critical Care)
Source: Critical Care - January 5, 2018 Category: Intensive Care Authors: Gentle Sunder Shrestha Tags: Letter Source Type: research

ICU-acquired weakness: should medical sovereignty belong to any specialist?
ICU-acquired weakness (ICUAW), including critical illness polyneuropathy, critical illness myopathy, and critical illness polyneuropathy and myopathy, is a frequent disabling disorder in ICU subjects. Research... (Source: Critical Care)
Source: Critical Care - January 4, 2018 Category: Intensive Care Authors: Domenico Intiso Tags: Viewpoint Source Type: research

Ultrasound-guided central venous catheter placement: first things first
(Source: Critical Care)
Source: Critical Care - December 29, 2017 Category: Intensive Care Authors: Bernd Saugel, Leonie Schulte-Uentrop, Thomas W. L. Scheeren and Jean-Louis Teboul Tags: Letter Source Type: research

Bronchoscopy versus an endotracheal tube mounted camera for the peri-interventional visualization of percutaneous dilatational tracheostomy - a prospective, randomized trial (VivaPDT)
Percutaneous dilatational tracheostomy (PDT) in critically ill patients often involves bronchoscopic optical guidance. However, this procedure is not without disadvantages. Therefore, we aimed to study a recen... (Source: Critical Care)
Source: Critical Care - December 29, 2017 Category: Intensive Care Authors: J örn Grensemann, Lars Eichler, Sophie Kähler, Dominik Jarczak, Marcel Simon, Hans O. Pinnschmidt and Stefan Kluge Tags: Research Source Type: research

Critical illness and flat batteries
An exaggerated, dysregulated host response to insults such as infection (i.e. sepsis), trauma and ischaemia-reperfusion injury can result in multiple organ dysfunction and death. While the focus of research in... (Source: Critical Care)
Source: Critical Care - December 28, 2017 Category: Intensive Care Authors: Mervyn Singer Tags: Review Source Type: research