A reply to analysis of static parameters in retrospective studies: limitations and interpretation
(Source: Critical Care)
Source: Critical Care - November 2, 2023 Category: Intensive Care Authors: Peter J. McGuigan, Elisa Giallongo, Alistair D. Nichol, Markus B. Skrifvars and Daniel F. McAuley Tags: Matters Arising Source Type: research

Subphenotypes in patients with acute respiratory distress syndrome treated with high-flow oxygen
Acute respiratory distress syndrome (ARDS) subphenotypes differ in outcomes and treatment responses. Subphenotypes in high-flow nasal oxygen (HFNO)-treated ARDS patients have not been investigated. (Source: Critical Care)
Source: Critical Care - November 1, 2023 Category: Intensive Care Authors: Pierre-Louis Blot, Benjamin G. Chousterman, Manel Santaf è, Jérôme Cartailler, Andrés Pacheco, Mònica Magret, Joan R. Masclans, Antoni Artigas, Oriol Roca and Marina García-de-Acilu Tags: Research Source Type: research

Correction: Plasma protein biomarkers reflective of the host response in patients developing Intensive Care Unit-acquired pneumonia
(Source: Critical Care)
Source: Critical Care - November 1, 2023 Category: Intensive Care Authors: Tjitske S. R. van Engelen, Tom D. Y. Reijnders, Fleur P. Paling, Marc J. M. Bonten, Leen Timbermont, Surbhi Malhotra-Kumar, Jan A. J. W. Kluytmans, Hessel Peters-Sengers and Tom van der Poll Tags: Correction Source Type: research

Human cytomegalovirus seropositivity is associated with reduced patient survival during sepsis
Sepsis is one of the leading causes of death. Treatment attempts targeting the immune response regularly fail in clinical trials. As HCMV latency can modulate the immune response and changes the immune cell co... (Source: Critical Care)
Source: Critical Care - October 31, 2023 Category: Intensive Care Authors: M. Unterberg, S. F. Ehrentraut, T. Bracht, A. Wolf, H. Haberl, A. von Busch, K. Rump, D. Ziehe, M. Bazzi, P. Thon, B. Sitek, K. Marcus, M. Bayer, K. Schork, M. Eisenacher, B. Ellger & hellip; Tags: Research Source Type: research

Utilization of spontaneous breathing trial, objective cough test, and diaphragmatic ultrasound results to predict extubation success: COBRE-US trial
The results of clinical and weaning readiness tests and the spontaneous breathing trial (SBT) are used to predict the success of the weaning process and extubation. (Source: Critical Care)
Source: Critical Care - October 31, 2023 Category: Intensive Care Authors: Fabio Var ón-Vega, Luis F. Giraldo-Cadavid, Ana María Uribe, Adriana Rincón, Jonathan Palacios, Stephanie Crevoisier, Eduardo Tuta-Quintero, Lina Ordoñez, Natalia Boada, Paola Rincón, Marcela Poveda and Pablo Monedero Tags: Research Source Type: research

How we approach titrating PEEP in patients with acute hypoxemic failure
(Source: Critical Care)
Source: Critical Care - October 31, 2023 Category: Intensive Care Authors: Leo Heunks, Lise Piquilloud and Alexandre Demoule Tags: Perspective Source Type: research

Redefining ARDS: a paradigm shift
Although the defining elements of “acute respiratory distress syndrome” (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its concept... (Source: Critical Care)
Source: Critical Care - October 31, 2023 Category: Intensive Care Authors: Jes ús Villar, Tamas Szakmany, Giacomo Grasselli and Luigi Camporota Tags: Perspective Source Type: research

Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial
The role of haloperidol as treatment for ICU delirium and related symptoms remains controversial despite two recent large controlled trials evaluating its efficacy and safety. We sought to determine whether ha... (Source: Critical Care)
Source: Critical Care - October 30, 2023 Category: Intensive Care Authors: Lisa Smit, Arjen J. C. Slooter, John W. Devlin, Zoran Trogrlic, Nicole G. M. Hunfeld, Robert Jan Osse, Huibert H. Ponssen, Arjen J. B. W. Brouwers, Jeannette F. Schoonderbeek, Koen S. Simons, Mark van den Boogaard, Judith A. Lens, Dirk P. Boer, Diederik A Tags: Research Source Type: research

Characteristics of pulmonary artery catheter use in multicenter ICUs in Japan and the association with mortality: a multicenter cohort study using the Japanese Intensive care PAtient Database
It has been 50 years since the pulmonary artery catheter was introduced, but the actual use of pulmonary artery catheters in recent years is unknown. Some randomized controlled trials have reported no causalit... (Source: Critical Care)
Source: Critical Care - October 28, 2023 Category: Intensive Care Authors: Kentaro Fukano, Yusuke Iizuka, Seiya Nishiyama, Koichi Yoshinaga, Shigehiko Uchino, Yusuke Sasabuchi and Masamitsu Sanui Tags: Research Source Type: research

ECMO in resuscitated drowning patients: a propensity score matched sub-analysis —a response to Jouffroy et al.
(Source: Critical Care)
Source: Critical Care - October 27, 2023 Category: Intensive Care Authors: Thomas Jasny, Jan Kloka, Oliver Old, Florian Piekarski, G östa Lotz, Kai Zacharowski and Benjamin Friedrichson Tags: Matters Arising Source Type: research

Serial assessments of cardiac output and mixed venous oxygen saturation in comatose patients after out-of-hospital cardiac arrest
To assess the association with outcomes of cardiac index (CI) and mixed venous oxygen saturation (SvO2) in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA). (Source: Critical Care)
Source: Critical Care - October 27, 2023 Category: Intensive Care Authors: Johannes Grand, Christian Hassager, Henrik Schmidt, Simon M ølstrøm, Benjamin Nyholm, Henrik Frederiksen Høigaard, Jordi S. Dahl, Martin Meyer, Rasmus P. Beske, Laust Obling, Jesper Kjaergaard and Jacob E. Møller Tags: Research Source Type: research

Correction to: Efficacy and safety of adjunctive corticosteroids in the treatment of severe community ‑acquired pneumonia: a systematic review and meta‑analysis of randomized controlled trials
(Source: Critical Care)
Source: Critical Care - October 27, 2023 Category: Intensive Care Authors: Jheng ‑Yan Wu, Ya‑Wen Tsai, Wan‑Hsuan Hsu, Ting‑Hui Liu, Po‑Yu Huang, Min‑Hsiang Chuang, Mei‑Yuan Liu and Chih‑Cheng Lai Tags: Correction Source Type: research

How I manage differential gas exchange in peripheral venoarterial extracorporeal membrane oxygenation
Dual circulation is a common but underrecognized physiological occurrence associated with peripheral venoarterial extracorporeal membrane oxygenation (ECMO). Competitive flow will develop between blood ejected... (Source: Critical Care)
Source: Critical Care - October 27, 2023 Category: Intensive Care Authors: Richa Asija, Justin A. Fried, Eric C. Siddall, Dana A. Mullin, Cara L. Agerstrand, Daniel Brodie, Joshua R. Sonett, Philippe H. Lemaitre and Darryl Abrams Tags: Perspective Source Type: research

Quantitative analysis of early apparent diffusion coefficient values from MRIs for predicting neurological prognosis in survivors of out-of-hospital cardiac arrest: an observational study
This study aimed to quantitatively analyse ultra-early brain diffusion-weighted magnetic resonance imaging (DW-MRI) findings to determine the apparent diffusion coefficient (ADC) threshold associated with neur... (Source: Critical Care)
Source: Critical Care - October 25, 2023 Category: Intensive Care Authors: Jung A. Yoon, Changshin Kang, Jung Soo Park, Yeonho You, Jin Hong Min, Yong Nam In, Wonjoon Jeong, Hong Joon Ahn, In Ho Lee, Hye Seon Jeong, Byung Kook Lee and Jae Kwang Lee Tags: Research Source Type: research

Interpretable machine learning models for predicting venous thromboembolism in the intensive care unit: an analysis based on data from 207 centers
Venous thromboembolism (VTE) is a severe complication in critically ill patients, often resulting in death and long-term disability and is one of the major contributors to the global burden of disease. This st... (Source: Critical Care)
Source: Critical Care - October 24, 2023 Category: Intensive Care Authors: Chengfu Guan, Fuxin Ma, Sijie Chang and Jinhua Zhang Tags: Research Source Type: research