Association of deranged cerebrovascular reactivity with brain injury following cardiac arrest: a post-hoc analysis of the COMACARE trial
Impaired cerebrovascular reactivity (CVR) is one feature of post cardiac arrest encephalopathy. We studied the incidence and features of CVR by near infrared spectroscopy (NIRS) and associations with outcome a... (Source: Critical Care)
Source: Critical Care - September 28, 2021 Category: Intensive Care Authors: Johanna Laurikkala, Anders Aneman, Alexander Peng, Matti Reinikainen, Paul Pham, Pekka Jakkula, Johanna H ästbacka, Erika Wilkman, Pekka Loisa, Jussi Toppila, Thomas Birkelund, Kaj Blennow, Henrik Zetterberg and Markus B. Skrifvars Tags: Research Source Type: research

The impact of wearable continuous vital sign monitoring on deterioration detection and clinical outcomes in hospitalised patients: a systematic review and meta-analysis
Timely recognition of the deteriorating inpatient remains challenging. Wearable monitoring systems (WMS) may augment current monitoring practices. However, there are many barriers to implementation in the hosp... (Source: Critical Care)
Source: Critical Care - September 28, 2021 Category: Intensive Care Authors: Carlos Areia, Christopher Biggs, Mauro Santos, Neal Thurley, Stephen Gerry, Lionel Tarassenko, Peter Watkinson and Sarah Vollam Tags: Research Source Type: research

The knowns and unknowns of perfusion disturbances in COVID-19 pneumonia
(Source: Critical Care)
Source: Critical Care - September 28, 2021 Category: Intensive Care Authors: Mattia Busana and Lorenzo Giosa Tags: Letter Source Type: research

Effectiveness of anisodamine for the treatment of critically ill patients with septic shock: a multicentre randomized controlled trial
Septic shock is characterized by an uncontrolled inflammatory response and microcirculatory dysfunction. There is currently no specific agent for treating septic shock. Anisodamine is an agent extracted from t... (Source: Critical Care)
Source: Critical Care - September 27, 2021 Category: Intensive Care Authors: Yuetian Yu, Cheng Zhu, Yucai Hong, Lin Chen, Zhiping Huang, Jiancang Zhou, Xin Tian, Dadong Liu, Bo Ren, Cao Zhang, Caibao Hu, Xinan Wang, Rui Yin, Yuan Gao and Zhongheng Zhang Tags: Research Source Type: research

Pneumocystis pneumonia risk among viral acute respiratory distress syndrome related or not to COVID 19
(Source: Critical Care)
Source: Critical Care - September 26, 2021 Category: Intensive Care Authors: Keyvan Razazi, Romain Arrestier, Anne Fleur Haudebourg, Francoise Botterel and Armand Mekontso Dessap Tags: Research Letter Source Type: research

Acute cor pulmonale in Covid-19 related acute respiratory distress syndrome
(Source: Critical Care)
Source: Critical Care - September 25, 2021 Category: Intensive Care Authors: Pedro Cavaleiro, Paul Masi, Fran çois Bagate, Thomas d’Humières and Armand Mekontso Dessap Tags: Research Letter Source Type: research

Restricted visitation policies in acute care settings during the COVID-19 pandemic: a scoping review
The objective of this scoping review is to identify impacts of restricted visitation policies ... (Source: Critical Care)
Source: Critical Care - September 25, 2021 Category: Intensive Care Authors: Stephana J. Moss, Karla D. Krewulak, Henry T. Stelfox, Sofia B. Ahmed, Melanie C. Anglin, Sean M. Bagshaw, Karen E. A. Burns, Deborah J. Cook, Christopher J. Doig, Alison Fox-Robichaud, Robert Fowler, Laura Hern ández, Michelle E. Kho, Maia Kredentser, K Tags: Research Source Type: research

Feasibility of machine integrated point of care lung ultrasound automatic B-lines tool in the Corona-virus 2019 critical care unit
(Source: Critical Care)
Source: Critical Care - September 24, 2021 Category: Intensive Care Authors: Gal Tsaban, Ori Galante, Yaniv Almog, Yuval Ullman and Lior Fuchs Tags: Research Letter Source Type: research

Differences in mortality in critically ill elderly patients during the second COVID-19 surge in Europe
The primary aim of this study was to assess the outcome of elderly intensive care unit (ICU) patients treated during the spring and autumn COVID-19 surges in Europe. (Source: Critical Care)
Source: Critical Care - September 23, 2021 Category: Intensive Care Authors: Christian Jung, Jesper Fj ølner, Raphael Romano Bruno, Bernhard Wernly, Antonio Artigas, Bernardo Bollen Pinto, Joerg C. Schefold, Georg Wolff, Malte Kelm, Michael Beil, Sigal Sviri, Peter Vernon van Heerden, Wojciech Szczeklik, Miroslaw Czuczwar, Michae Tags: Research Source Type: research

Does inspiration of exhaled CO2 explain improved oxygenation with a face mask plus high-flow nasal cannula oxygen in severe COVID-19 infection?
(Source: Critical Care)
Source: Critical Care - September 20, 2021 Category: Intensive Care Authors: Erik R. Swenson Tags: Letter Source Type: research

Lung ultrasound in a tertiary intensive care unit population: a diagnostic accuracy study
Evidence from previous studies comparing lung ultrasound to thoracic computed tomography (CT) in intensive care unit (ICU) patients is limited due to multiple methodologic weaknesses. While addressing methodol... (Source: Critical Care)
Source: Critical Care - September 17, 2021 Category: Intensive Care Authors: Jasper M. Smit, Mark E. Haaksma, Michiel H. Winkler, Micah L. A. Heldeweg, Luca Arts, Erik J. Lust, Paul W. G. Elbers, Lilian J. Meijboom, Armand R. J. Girbes, Leo M. A. Heunks and Pieter R. Tuinman Tags: Research Source Type: research

Early versus late awake prone positioning in non-intubated patients with COVID-19
Awake prone positioning (APP) is widely used in the management of patients with coronavirus disease (COVID-19). The primary objective of this study was to compare the outcome of COVID-19 patients who received ... (Source: Critical Care)
Source: Critical Care - September 17, 2021 Category: Intensive Care Authors: Ramandeep Kaur, David L. Vines, Sara Mirza, Ahmad Elshafei, Julie A. Jackson, Lauren J. Harnois, Tyler Weiss, J. Brady Scott, Matthew W. Trump, Idrees Mogri, Flor Cerda, Amnah A. Alolaiwat, Amanda R. Miller, Andrew M. Klein, Trevor W. Oetting, Lindsey Mor Tags: Research Source Type: research

A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes
Approximately one-third of sepsis patients experience poor outcomes including chronic critical illness (CCI, intensive care unit (ICU) stay  > 14 days) or early death (in-hospital death within 14 days). We soug... (Source: Critical Care)
Source: Critical Care - September 17, 2021 Category: Intensive Care Authors: Faheem W. Guirgis, Lauren Page Black, Morgan Henson, Guillaume Labilloy, Carmen Smotherman, Charlotte Hopson, Ian Tfirn, Elizabeth L. DeVos, Christiaan Leeuwenburgh, Lyle Moldawer, Susmita Datta, Todd M. Brusko, Alexis Hester, Andrew Bertrand, Victor Grij Tags: Research Source Type: research

The lonely glutamine tree in the middle of the infinite critically ill forest
(Source: Critical Care)
Source: Critical Care - September 17, 2021 Category: Intensive Care Authors: Panagiotis Briassoulis, Stavroula Ilia, Efrossini Briassouli, Marianna Miliaraki and George Briassoulis Tags: Letter Source Type: research

Short and long-term outcomes of patients with COVID-19-associated acute respiratory distress syndrome and difficult veno-venous-ECMO weaning
(Source: Critical Care)
Source: Critical Care - September 16, 2021 Category: Intensive Care Authors: Paul Masi, Samuel Tuffet, Laurent Boyer, Thierry Folliguet, Armand Mekontso Dessap and Nicolas de Prost Tags: Research Letter Source Type: research