Gut mycobiome dysbiosis after sepsis and trauma
Sepsis and trauma are known to disrupt gut bacterial microbiome communities, but the impacts and perturbations in the fungal (mycobiome) community after severe infection or injury, particularly in patients exp... (Source: Critical Care)
Source: Critical Care - January 11, 2024 Category: Intensive Care Authors: Gwoncheol Park, Jennifer A. Munley, Lauren S. Kelly, Kolenkode B. Kannan, Robert T. Mankowski, Ashish Sharma, Gilbert Upchurch, Gemma Casadesus, Paramita Chakrabarty, Shannon M. Wallet, Robert Maile, Letitia E. Bible, Bo Wang, Lyle L. Moldawer, Alicia M. Tags: Research Source Type: research

Triggering receptor expressed on myeloid cells-1 in sepsis, and current insights into clinical studies
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recognition receptor and plays a critical role in the immune response. TREM-1 activation leads to the production and release of proinflamm... (Source: Critical Care)
Source: Critical Care - January 9, 2024 Category: Intensive Care Authors: Vivienne Theobald, Felix Carl Fabian Schmitt, Chiara Simone Middel, Lena Gaissmaier, Thorsten Brenner and Markus Alexander Weigand Tags: Review Source Type: research

To identify Harlequin syndrome in patients with venoarterial extracorporeal membrane oxygenation using radial near-infrared spectroscopy
(Source: Critical Care)
Source: Critical Care - January 8, 2024 Category: Intensive Care Authors: Yongwei Yu, Xing Fang, Zhipeng Xu, Tong Li and Jueyue Yan Tags: Correspondence Source Type: research

The effects of higher versus lower protein delivery in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials with trial sequential analysis
A recent large multicentre trial found no difference in clinical outcomes but identified a possibility of increased mortality rates in patients with acute kidney injury (AKI) receiving higher protein. These al... (Source: Critical Care)
Source: Critical Care - January 6, 2024 Category: Intensive Care Authors: Zheng-Yii Lee, Ellen Dresen, Charles Chin Han Lew, Julia Bels, Aileen Hill, M. Shahnaz Hasan, Lu Ke, Arthur van Zanten, Marcel C. G. van de Poll, Daren K. Heyland and Christian Stoppe Tags: Research Source Type: research

Life-threatening complications and intensive care unit management in patients treated with blinatumomab for B-cell acute lymphoblastic leukemia
(Source: Critical Care)
Source: Critical Care - January 5, 2024 Category: Intensive Care Authors: Irene Urbino, Etienne Lenglin é, Sandrine Valade, Marco Cerrano, Marie Sebert, Emmanuel Raffoux, Florence Rabian, Elie Azoulay and Nicolas Boissel Tags: Correspondence Source Type: research

Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis
The objective of the study is to assess the effect of adjunct ... (Source: Critical Care)
Source: Critical Care - January 4, 2024 Category: Intensive Care Authors: Vladimir Kuklin, Michael Sovershaev, Johan Bjerner, Philip Keith, L. Keith Scott, Owen Matthew Truscott Thomas, Wladimir Szpirt, Gail Rock and Bernd Stegmayr Tags: Review Source Type: research

Fever or hypothermia following ECMO decannulation: the association of body temperature with survival
(Source: Critical Care)
Source: Critical Care - January 4, 2024 Category: Intensive Care Authors: Markus Busch, Benjamin Seeliger, Jan Fuge, Marius M. Hoeper and Klaus Stahl Tags: Correspondence Source Type: research

Single-drug versus combination antimicrobial therapy in critically ill patients with hospital-acquired pneumonia and ventilator-associated pneumonia due to Gram-negative pathogens: a multicenter retrospective cohort study
In this study including 391 critically ill patients with nosocomial pneumonia due to Gram-negative pathogens, combination therapy was not associated with a reduced hazard of death at Day 28 or a greater likeli... (Source: Critical Care)
Source: Critical Care - January 3, 2024 Category: Intensive Care Authors: Fran çois Barbier, Claire Dupuis, Niccolò Buetti, Carole Schwebel, Élie Azoulay, Laurent Argaud, Yves Cohen, Vivien Hong Tuan Ha, Marc Gainnier, Shidasp Siami, Jean-Marie Forel, Christophe Adrie, Étienne de Montmollin, Jean Reignier, Stéphane Ruckly, Tags: Research Source Type: research

Correction to: Bayesian methods: a potential path forward for sepsis trials
(Source: Critical Care)
Source: Critical Care - January 3, 2024 Category: Intensive Care Authors: George Tomlinson, Ali Al-Khafaji, Steven A. Conrad, Faith N. F. Factora, Debra M. Foster, Claude Galphin, Kyle J. Gunnerson, Sobia Khan, Roopa Kohli-Seth, Paul McCarthy, Nikhil K. Meena, Ronald G. Pearl, Jean-Sebastien Rachoin, Ronald Rains, Michael Senef Tags: Correction Source Type: research

Expanding the scope of prehabilitation: reducing critical illness weakness across elective surgical patients scheduled for postoperative ICU care
(Source: Critical Care)
Source: Critical Care - January 2, 2024 Category: Intensive Care Authors: Wen Gao and Jingfen Jin Tags: Comment Source Type: research

Lost in a number: concealed heterogeneity within the sequential organ failure assessment (SOFA) score
(Source: Critical Care)
Source: Critical Care - January 2, 2024 Category: Intensive Care Authors: Neville Dusaj, Eleni Papoutsi, Katherine L. Hoffman, Ilias I. Siempos and Edward James Schenck Tags: Correspondence Source Type: research

Immature neutrophils and myeloid-derived suppressor cells in sepsis: differences in occurrence kinetics
(Source: Critical Care)
Source: Critical Care - January 2, 2024 Category: Intensive Care Authors: R émy Coudereau, Muzhda Haem Rahimi, Anne-Claire Lukaszewicz, Martin Cour, Frank Bidar, Laurent Argaud, Fabienne Venet and Guillaume Monneret Tags: Correspondence Source Type: research

Does inflammation and altered metabolism impede efficacy of functional electrical stimulation in critically ill patients? Unleashing the potential of individualized functional electrical stimulation-cycling in critical illness
(Source: Critical Care)
Source: Critical Care - January 2, 2024 Category: Intensive Care Authors: Murillo Fraz ão, Gerson Cipriano Jr. and Paulo Eugênio Silva Tags: Matters Arising Source Type: research

Reply to “Potential confounders in linking elevated S100A8/A9 to left ventricular dysfunction in septic shock patients”
(Source: Critical Care)
Source: Critical Care - January 2, 2024 Category: Intensive Care Authors: Gabriel Jakobsson, Henrik Andersson, Michelle Chew and Alexandru Schiopu Tags: Matters Arising Source Type: research

Overestimation of driving pressure by the analysis of the conductive pressure during venous-arterial ECMO: Airway Closure or Intrinsic PEEP?
(Source: Critical Care)
Source: Critical Care - December 21, 2023 Category: Intensive Care Authors: Emanuele Rezoagli, Matteo Pozzi, Maurizio Cereda and Giuseppe Foti Tags: Correspondence Source Type: research