Termination-of-resuscitation rule in the emergency department for patients with refractory out-of-hospital cardiac arrest: a nationwide, population-based observational study
In Japan, emergency medical service (EMS) providers are prohibited from field termination-of-resuscitation (TOR) in out-of-hospital cardiac arrest (OHCA) patients. In 2013, we developed a TOR rule for emergenc... (Source: Critical Care)
Source: Critical Care - May 16, 2022 Category: Intensive Care Authors: Yoshikazu Goto, Akira Funada, Tetsuo Maeda and Yumiko Goto Tags: Research Source Type: research

Impact of prolonged requirement for insulin on 90-day mortality in critically ill patients without previous diabetic treatments: a post hoc analysis of the CONTROLING randomized control trial
Stress hyperglycemia can persist during an intensive care unit (ICU) stay and result in prolonged requirement for insulin (PRI). The impact of PRI on ICU patient outcomes is not known. We evaluated the relatio... (Source: Critical Care)
Source: Critical Care - May 16, 2022 Category: Intensive Care Authors: Fran çois Thouy, Julien Bohé, Bertrand Souweine, Hassane Abidi, Jean-Pierre Quenot, Fabrice Thiollière, Jean Dellamonica, Jean-Charles Preiser, Jean-François Timsit, Vincent Brunot, Amna Klich, Nicholas Sedillot, Xavier Tchenio, Jean-Baptiste Roudaut, Tags: Research Source Type: research

Correction to: Pain and sedation management and monitoring in pediatric intensive care units across Europe: an ESPNIC survey
(Source: Critical Care)
Source: Critical Care - May 16, 2022 Category: Intensive Care Authors: Marco Daverio, Florian von Borell, Anne-Sylvie Ramelet, Francesca Sperotto, Paula Pokorna, Sebastian Brenner, Maria Cristina Mondardini, Dick Tibboel, Angela Amigoni and Erwin Ista Tags: Correction Source Type: research

Prevalence and prognostic value of preexisting sarcopenia in patients with mechanical ventilation: a systematic review and meta-analysis
Sarcopenia is defined as age-related loss of muscle mass, strength, and/or function in the context of aging. Mechanical ventilation (MV) is one of the most frequently used critical care technologies in critica... (Source: Critical Care)
Source: Critical Care - May 16, 2022 Category: Intensive Care Authors: Tingting Jiang, Taiping Lin, Xiaoyu Shu, Quhong Song, Miao Dai, Yanli Zhao, Li Huang, Xiangping Tu and Jirong Yue Tags: Review Source Type: research

Hospital-onset sepsis and community-onset sepsis in critical care units in Japan: a retrospective cohort study based on a Japanese administrative claims database
This study aimed to describe the epidemiology of hospital- and community-onset sepsis... (Source: Critical Care)
Source: Critical Care - May 13, 2022 Category: Intensive Care Authors: Mayuko Tonai, Atsushi Shiraishi, Toshiyuki Karumai, Akira Endo, Hirotada Kobayashi, Kiyohide Fushimi and Yoshiro Hayashi Tags: Research Source Type: research

Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial
Many critically ill children face long-term developmental impairments. The PEPaNIC trial attributed part of the problems at the level of neurocognitive and emotional/behavioral development to early use of pare... (Source: Critical Care)
Source: Critical Care - May 12, 2022 Category: Intensive Care Authors: Ilse Vanhorebeek, An Jacobs, Liese Mebis, Karolijn Dulfer, Renate Eveleens, Hanna Van Cleemput, Pieter J. Wouters, Ines Verlinden, Koen Joosten, Sascha Verbruggen and Greet Van den Berghe Tags: Research Source Type: research

Clinical and biochemical endpoints and predictors of response to plasma exchange in septic shock: results from a randomized controlled trial
Recently, a randomized controlled trial (RCT) demonstrated rapid but individually variable hemodynamic improvement with therapeutic plasma exchange (TPE) in patients with septic shock. Prediction of clinical e... (Source: Critical Care)
Source: Critical Care - May 12, 2022 Category: Intensive Care Authors: Klaus Stahl, Philipp Wand, Benjamin Seeliger, Pedro David Wendel-Garcia, Julius J. Schmidt, Bernhard M. W. Schmidt, Andrea Sauer, Felix Lehmann, Ulrich Budde, Markus Busch, Olaf Wiesner, Tobias Welte, Hermann Haller, Heiner Wedemeyer, Christian Putensen, Tags: Research Source Type: research

Hemoperfusion: technical aspects and state of the art
Blood purification through the removal of plasma solutes by adsorption to beads of charcoal or resins contained in a cartridge (hemoperfusion) has a long and imperfect history. Developments in production and c... (Source: Critical Care)
Source: Critical Care - May 12, 2022 Category: Intensive Care Authors: Claudio Ronco and Rinaldo Bellomo Tags: Review Source Type: research

Correction: The effect of treatment and clinical course during Emergency Department stay on severity scoring and predicted mortality risk in Intensive Care patients
(Source: Critical Care)
Source: Critical Care - May 11, 2022 Category: Intensive Care Authors: Bart G. J. Candel, Wouter Raven, Heleen Lameijer, Wendy A. M. H. Thijssen, Fabian Termorshuizen, Christiaan Boerma, Nicolette F. de Keizer, Evert de Jonge and Bas de Groot Tags: Correction Source Type: research

Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan
The prevalence of extracorporeal cardiopulmonary resuscitation (ECPR) in patients with out-of-hospital cardiac arrest (OHCA) has been increasing rapidly worldwide. However, guidelines or clinical studies do no... (Source: Critical Care)
Source: Critical Care - May 9, 2022 Category: Intensive Care Authors: Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Hiroshi Okamoto, Jun Kunikata, Hideto Yokoi, Hirotaka Sawano, Yuko Egawa, Shunichi Kato, Kazuhiro Sugiyama, Naofumi Bunya, Takehiko Kasai, Shinichi Ijuin, Shinichi Nakayama, Jun Kanda, Seiya Kanou & hellip; Tags: Research Source Type: research

Diagnostic concordance between BioFire ® FilmArray® Pneumonia Panel and culture in patients with COVID-19 pneumonia admitted to intensive care units: the experience of the third wave in eight hospitals in Colombia
The detection of coinfections is important to initiate appropriate antimicrobial therapy. Molecular diagnostic testing identifies pathogens at a greater rate than conventional microbiology. We assessed both ba... (Source: Critical Care)
Source: Critical Care - May 9, 2022 Category: Intensive Care Authors: Francisco Jos é Molina, Luz Elena Botero, Juan Pablo Isaza, Luz Elena Cano, Lucelly López, Leidy Tamayo and Antoni Torres Tags: Research Source Type: research

Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials
Thrombotic microangiopathy-induced thrombocytopenia-associated multiple organ failure and hyperinflammatory macrophage activation syndrome are important causes of late pediatric sepsis mortality that are often mi... (Source: Critical Care)
Source: Critical Care - May 7, 2022 Category: Intensive Care Authors: Yidi Qin, Kate F. Kernan, Zhenjiang Fan, Hyun-Jung Park, Soyeon Kim, Scott W. Canna, John A. Kellum, Robert A. Berg, David Wessel, Murray M. Pollack, Kathleen Meert, Mark Hall, Christopher Newth, John C. Lin, Allan Doctor, Tom Shanley & hellip; Tags: Research Source Type: research

Lung response to prone positioning in mechanically-ventilated patients with COVID-19
Prone positioning improves survival in moderate-to-severe acute respiratory distress syndrome (ARDS) unrelated to the novel coronavirus disease (COVID-19). This benefit is probably mediated by a decrease in al... (Source: Critical Care)
Source: Critical Care - May 7, 2022 Category: Intensive Care Authors: Alessandro Protti, Alessandro Santini, Francesca Pennati, Chiara Chiurazzi, Michele Ferrari, Giacomo E. Iapichino, Luca Carenzo, Francesca Dalla Corte, Ezio Lanza, Nicol ò Martinetti, Andrea Aliverti and Maurizio Cecconi Tags: Research Source Type: research

Early intubation and decreased in-hospital mortality in patients with coronavirus disease 2019
Some academic organizations recommended that physicians intubate patients with COVID-19 with a relatively lower threshold of oxygen usage particularly in the early phase of pandemic. We aimed to elucidate whet... (Source: Critical Care)
Source: Critical Care - May 6, 2022 Category: Intensive Care Authors: Ryo Yamamoto, Daiki Kaito, Koichiro Homma, Akira Endo, Takashi Tagami, Morio Suzuki, Naoyuki Umetani, Masayuki Yagi, Eisaku Nashiki, Tomohiro Suhara, Hiromasa Nagata, Hiroki Kabata, Koichi Fukunaga, Kazuma Yamakawa, Mineji Hayakawa, Takayuki Ogura & helli Tags: Research Source Type: research

When to start vasopressin in septic shock: the strategy we propose
(Source: Critical Care)
Source: Critical Care - May 6, 2022 Category: Intensive Care Authors: Philippe Guerci, Thibaut Belveyre, Nicolas Mongardon and Emmanuel Novy Tags: Comment Source Type: research