High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients after planned extubation
(Source: Critical Care)
Source: Critical Care - November 5, 2019 Category: Intensive Care Authors: Meng-Si Luo, Guan-Jiang Huang and Lun Wu Tags: Letter Source Type: research

Caution should be taken when using electronic health record database
(Source: Critical Care)
Source: Critical Care - November 5, 2019 Category: Intensive Care Authors: Lina Wang and Xiaoming Wu Tags: Letter Source Type: research

NT-proBNP levels might predict outcomes in severe sepsis, but renal function cannot be ignored
(Source: Critical Care)
Source: Critical Care - November 4, 2019 Category: Intensive Care Authors: Jiarong Ye, Qianrong Liang and Xiaotu Xi Tags: Letter Source Type: research

Intracranial hypertension and deep sedation
(Source: Critical Care)
Source: Critical Care - November 4, 2019 Category: Intensive Care Authors: Guillermo Bugedo and C ésar Santis Tags: Letter Source Type: research

Hemoadsorption efficacy for uncomplicated high-risk cardiac surgery
(Source: Critical Care)
Source: Critical Care - November 4, 2019 Category: Intensive Care Authors: S ébastien Redant, Matthieu Legrand, Yael Langman, Alejandra Garcia Aguilar, François Angoulvant, Keitiane Kaefer, David De Bels, Rachid Attou, Kianoush Kashani and Patrick M. Honore Tags: Letter Source Type: research

The place of dexmedetomidine light sedation in patients with acute brain injury
(Source: Critical Care)
Source: Critical Care - November 1, 2019 Category: Intensive Care Authors: Simone Carelli, Gennaro De Pascale, Nicoletta Filetici, Maria Grazia Bocci, Gian Marco Maresca, Salvatore Lucio Cutuli, Cecilia Maria Pizzo, Giuseppe Bello, Luca Montini, Anselmo Caricato, Giorgio Conti and Massimo Antonelli Tags: Letter Source Type: research

Adaptive mechanical ventilation with automated minimization of mechanical power —a pilot randomized cross-over study
Adaptive mechanical ventilation automatically adjusts respiratory rate (RR) and tidal volume (VT) to deliver the clinically desired minute ventilation, selecting RR and VT based on Otis ’ equation on least work of... (Source: Critical Care)
Source: Critical Care - October 30, 2019 Category: Intensive Care Authors: Tobias Becher, Anna Adelmeier, In éz Frerichs, Norbert Weiler and Dirk Schädler Tags: Research Source Type: research

What should be the best dialysis catheter lock in critically ill patients?
(Source: Critical Care)
Source: Critical Care - October 30, 2019 Category: Intensive Care Authors: Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani and David De Bels Tags: Letter Source Type: research

Preparing intensive care for the next pandemic influenza
Few viruses have shaped the course of human history more than influenza viruses. A century since the 1918 –1919 Spanish influenza pandemic—the largest and deadliest influenza pandemic in recorded history—we hav... (Source: Critical Care)
Source: Critical Care - October 30, 2019 Category: Intensive Care Authors: Taylor Kain and Robert Fowler Tags: Review Source Type: research

Clinical significance of lymphocytopenia in patients hospitalized with pneumonia caused by influenza virus
(Source: Critical Care)
Source: Critical Care - October 29, 2019 Category: Intensive Care Authors: Valeria Bellelli, Gabriella d ’Ettorre, Luigi Celani, Cristian Borrazzo, Giancarlo Ceccarelli and Mario Venditti Tags: Letter Source Type: research

How levosimendan can improve renal function?
(Source: Critical Care)
Source: Critical Care - October 29, 2019 Category: Intensive Care Authors: Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani and David De Bels Tags: Letter Source Type: research

Positive cultures and clinical outcomes in septic patients: be aware of the influence from patient selection and the in-hospital confounders
(Source: Critical Care)
Source: Critical Care - October 29, 2019 Category: Intensive Care Authors: Romain Jouffroy and Beno ît Vivien Tags: Letter Source Type: research

Prognostic performance of age-adapted SOFA and qSOFA in septic children
(Source: Critical Care)
Source: Critical Care - October 29, 2019 Category: Intensive Care Authors: Xuepeng Zhang, Xiying Gui, Kaiying Yang, Siyuan Chen and Yi Ji Tags: Letter Source Type: research

Comment upon “Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest”
(Source: Critical Care)
Source: Critical Care - October 29, 2019 Category: Intensive Care Authors: Benjamin Post, Dominic Peter Douglas Nielsen and Anil Visram Tags: Letter Source Type: research

Obesity inducing acute respiratory distress syndrome: we should choose the right population!
(Source: Critical Care)
Source: Critical Care - October 28, 2019 Category: Intensive Care Authors: Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani and David De Bels Tags: Research Letter Source Type: research

SSEP retains its value as predictor of poor outcome following cardiac arrest in the era of therapeutic hypothermia
To re-evaluate the role of median nerve somatosensory evoked potentials (SSEPs) and bilateral loss of the N20 cortical wave as a predictor of unfavorable outcome in comatose patients following cardiac arrest (... (Source: Critical Care)
Source: Critical Care - October 23, 2019 Category: Intensive Care Authors: Ted L. Rothstein Tags: Review Source Type: research

Rescue fecal microbiota transplantation for antibiotic-associated diarrhea in critically ill patients
Antibiotic-associated diarrhea (AAD) is a risk factor for exacerbating the outcome of critically ill patients. Dysbiosis induced by the exposure to antibiotics reveals the potential therapeutic role of fecal m... (Source: Critical Care)
Source: Critical Care - October 21, 2019 Category: Intensive Care Authors: Min Dai, Yafei Liu, Wei Chen, Heena Buch, Yi Shan, Liuhui Chang, Yong Bai, Chen Shen, Xiaoyin Zhang, Yufeng Huo, Dian Huang, Zhou Yang, Zhihang Hu, Xuwei He, Junyu Pan, Lili Hu & hellip; Tags: Research Source Type: research

Correction to: Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials
In the publication of this article [1], there was an error in a contributors Family Name. This has now been updated in the original article. (Source: Critical Care)
Source: Critical Care - October 21, 2019 Category: Intensive Care Authors: Luca Cabrini, Giovanni Landoni, Martina Baiardo Redaelli, Omar Saleh, Carmine D. Votta, Evgeny Fominskiy, Alessandro Putzu, C ézar Daniel Snak de Souza, Massimo Antonelli, Rinaldo Bellomo, Paolo Pelosi and Alberto Zangrillo Tags: Correction Source Type: research

How I optimize power to avoid VILI
(Source: Critical Care)
Source: Critical Care - October 21, 2019 Category: Intensive Care Authors: John J. Marini Tags: Editorial Source Type: research

Early prognostication of neurological outcome by heart rate variability in adult patients with out-of-hospital sudden cardiac arrest
Most deaths of comatose survivors of out-of-hospital sudden cardiac arrest result from withdrawal of life-sustaining treatment (WLST) decisions based on poor neurological prognostication and the family ’s inten... (Source: Critical Care)
Source: Critical Care - October 17, 2019 Category: Intensive Care Authors: Hiroshi Endoh, Natuo Kamimura, Hiroyuki Honda and Masakazu Nitta Tags: Research Source Type: research

Correction to: Procalcitonin levels in candidemia versus bacteremia: a systematic review
The author wish to note there are three imprecisions in the article [1]. (Source: Critical Care)
Source: Critical Care - October 11, 2019 Category: Intensive Care Authors: Andrea Cortegiani, Giovanni Misseri, Mariachiara Ippolito, Matteo Bassetti, Antonino Giarratano, Ignacio Martin-Loeches and Sharon Einav Tags: Correction Source Type: research

How I wean patients from veno-venous extra-corporeal membrane oxygenation
(Source: Critical Care)
Source: Critical Care - September 18, 2019 Category: Intensive Care Authors: Francesco Vasques, Federica Romitti, Luciano Gattinoni and Luigi Camporota Tags: Editorial Source Type: research

Hemoadsorption with CytoSorb shows a decreased observed versus expected 28-day all-cause mortality in ICU patients with septic shock: a propensity-score-weighted retrospective study
Innovative treatment modalities have not yet shown a clinical benefit in patients with septic shock. To reduce severe cytokinaemia, CytoSorb as an add-on to continuous renal replacement therapy (CRRT) showed p... (Source: Critical Care)
Source: Critical Care - September 18, 2019 Category: Intensive Care Authors: Willem Pieter Brouwer, Servet Duran, Martijn Kuijper and Can Ince Tags: Research Source Type: research

Preoxygenation before intubation in adult patients with acute hypoxemic respiratory failure: a network meta-analysis of randomized trials
Patients with acute hypoxemic respiratory failure are at risk for life-threatening complications during endotracheal intubation. Preoxygenation might help reduce the risk of hypoxemia and intubation-related co... (Source: Critical Care)
Source: Critical Care - September 18, 2019 Category: Intensive Care Authors: Ka Man Fong, Shek Yin Au and George Wing Yiu Ng Tags: Research Source Type: research

Epinephrine, inodilator, or no inotrope in venoarterial extracorporeal membrane oxygenation implantation: a single-center experience
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) can be a rescue therapy for patients in cardiogenic shock or in refractory cardiac arrest. After cannulation, vasoplegia and cardiac depression are fr... (Source: Critical Care)
Source: Critical Care - September 18, 2019 Category: Intensive Care Authors: Viviane Zotzmann, Jonathan Rilinger, Corinna N. Lang, Klaus Kaier, Christoph Benk, Daniel Duerschmied, Paul M. Biever, Christoph Bode, Tobias Wengenmayer and Dawid L. Staudacher Tags: Research Source Type: research

Myocardial ischemia during ventilator weaning: a prospective multicenter cohort study
Weaning-induced cardiac pulmonary edema (WiPO) is one of the main mechanisms of weaning failure during mechanical ventilation. We hypothesized that weaning-induced cardiac ischemia (WiCI) may contribute to wea... (Source: Critical Care)
Source: Critical Care - September 18, 2019 Category: Intensive Care Authors: Alexandre Bedet, Fran çoise Tomberli, Gwenael Prat, Pierre Bailly, Achille Kouatchet, Sater Mortaza, Emmanuel Vivier, Sylvene Rosselli, Larissa Lipskaia, Guillaume Carteaux, Keyvan Razazi and Armand Mekontso Dessap Tags: Research Source Type: research

Candida bloodstream infection under veno-arterial ECMO therapy
(Source: Critical Care)
Source: Critical Care - September 17, 2019 Category: Intensive Care Authors: Quentin de Roux, Fran çoise Botterel, Raphaël Lepeule, Fabio Silvio Taccone, Olivier Langeron and Nicolas Mongardon Tags: Letter Source Type: research

Letter by Neugebauer et al. regarding article “Hypothermia after decompressive hemicraniectomy in treatment of malignant middle cerebral artery stroke: comment on the randomized clinical trial”
(Source: Critical Care)
Source: Critical Care - September 17, 2019 Category: Intensive Care Authors: Hermann Neugebauer, Hauke Schneider and Rainer Kollmar Tags: Letter Source Type: research

What is the best core measure after critical illness when the IES-R is no longer accessible for new researchers?
(Source: Critical Care)
Source: Critical Care - September 13, 2019 Category: Intensive Care Authors: Reba Umberger Tags: Letter Source Type: research

Comparison of echocardiographic indices of right ventricular systolic function and ejection fraction obtained with continuous thermodilution in critically ill patients
Though echocardiographic evaluation assesses the right ventricular systolic function, which of the existing parameters best reflects the right ventricular ejection fraction (RVEF) in the critically ill patient... (Source: Critical Care)
Source: Critical Care - September 13, 2019 Category: Intensive Care Authors: Romain Barth élémy, Xavier Roy, Tujia Javanainen, Alexandre Mebazaa and Benjamin Glenn Chousterman Tags: Research Source Type: research

Transfusion practice in the non-bleeding critically ill: an international online survey —the TRACE survey
Over the last decade, multiple large randomized controlled trials have studied alternative transfusion strategies in critically ill patients, demonstrating the safety of restrictive transfusion strategies. Due... (Source: Critical Care)
Source: Critical Care - September 11, 2019 Category: Intensive Care Authors: Sanne de Bruin, Thomas W. L. Scheeren, Jan Bakker, Robin van Bruggen and Alexander P. J. Vlaar Tags: Research Source Type: research

SEA-mulation: training for technical treatment related to emergency situations in maritime environment
(Source: Critical Care)
Source: Critical Care - September 11, 2019 Category: Intensive Care Authors: Brice Lodd é, Gael-Emgan Querellou, Alexandre Morel and Erwan L’Her Tags: Letter Source Type: research

Relationship of mottling score, skin microcirculatory perfusion indices and biomarkers of endothelial dysfunction in patients with septic shock: an observational study
In patients with septic shock, the skin is often chosen for the evaluation of peripheral perfusion and oxygenation. Changes in skin microcirculatory vessel oxygen saturation and relative hemoglobin concentrati... (Source: Critical Care)
Source: Critical Care - September 11, 2019 Category: Intensive Care Authors: Sigita Kazune, Anastasija Caica, Karina Volceka, Olegs Suba, Uldis Rubins and Andris Grabovskis Tags: Research Source Type: research

Differential contractile response of critically ill patients to neuromuscular electrical stimulation
Neuromuscular electrical stimulation (NMES) has been investigated as a preventative measure for intensive care unit-acquired weakness. Trial results remain contradictory and therefore inconclusive. As it has b... (Source: Critical Care)
Source: Critical Care - September 10, 2019 Category: Intensive Care Authors: Julius J. Grunow, Moritz Goll, Niklas M. Carbon, Max E. Liebl, Steffen Weber-Carstens and Tobias Wollersheim Tags: Research Source Type: research

Neuromuscular blocking agents for acute respiratory distress syndrome: how did we get conflicting results?
(Source: Critical Care)
Source: Critical Care - September 6, 2019 Category: Intensive Care Authors: Heather Torbic, Sudhir Krishnan and Abhijit Duggal Tags: Letter Source Type: research

Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure
Acute respiratory failure is the leading reason for intensive care unit (ICU) admission in immunocompromised patients, and the need for invasive mechanical ventilation has become a major clinical endpoint in r... (Source: Critical Care)
Source: Critical Care - September 6, 2019 Category: Intensive Care Authors: Guillaume Dumas, Alexandre Demoule, Djamel Mokart, Virginie Lemiale, Saad Nseir, Laurent Argaud, Fr édéric Pène, Loay Kontar, Fabrice Bruneel, Kada Klouche, François Barbier, Jean Reignier, Annabelle Stoclin, Guillaume Louis, Jean-Michel Constantin, F Tags: Research Source Type: research

Impact of species and antibiotic therapy of enterococcal peritonitis on 30-day mortality in critical care —an analysis of the OUTCOMEREA database
Enterococcus species are associated with an increased morbidity in intraabdominal infections (IAI). However, their impact on mortality remains uncertain. Moreover, the influence on outcome of the appropriate or i... (Source: Critical Care)
Source: Critical Care - September 6, 2019 Category: Intensive Care Authors: Anne-C écile Morvan, Baptiste Hengy, Maïté Garrouste-Orgeas, Stéphane Ruckly, Jean-Marie Forel, Laurent Argaud, Thomas Rimmelé, Jean-Pierre Bedos, Elie Azoulay, Claire Dupuis, Bruno Mourvillier, Carole Schwebel and Jean-François Timsit Tags: Research Source Type: research

Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS) —a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy
Part of the pathophysiology in septic shock is a progressive activation of the endothelium and platelets leading to widespread microvascular injury with capillary leakage, microthrombi and consumption coagulop... (Source: Critical Care)
Source: Critical Care - September 5, 2019 Category: Intensive Care Authors: Rasmus Ehrenfried Berthelsen, Sisse Rye Ostrowski, Morten Heiberg Bestle and Per Ingemar Johansson Tags: Research Source Type: research

Recombinant human soluble thrombomodulin in patients with sepsis-associated coagulopathy (SCARLET): an updated meta-analysis
(Source: Critical Care)
Source: Critical Care - September 5, 2019 Category: Intensive Care Authors: Kazuma Yamakawa, Jerrold H. Levy and Toshiaki Iba Tags: Letter Source Type: research

Host susceptibility to severe influenza A virus infection
Most people exposed to a new flu virus do not notice any symptoms. A small minority develops critical illness. Some of this extremely broad variation in susceptibility is explained by the size of the initial i... (Source: Critical Care)
Source: Critical Care - September 5, 2019 Category: Intensive Care Authors: Sara Clohisey and John Kenneth Baillie Tags: Review Source Type: research

Sevoflurane and nephrogenic diabetes insipidus on the rise: copeptin to the rescue?
(Source: Critical Care)
Source: Critical Care - September 5, 2019 Category: Intensive Care Authors: Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani and Willem Boer Tags: Letter Source Type: research

Endotoxin removal by polymyxin B: is it a question of dose or duration or both?
(Source: Critical Care)
Source: Critical Care - September 4, 2019 Category: Intensive Care Authors: Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani and Willem Boer Tags: Letter Source Type: research

The association between premorbid beta blocker exposure and mortality in sepsis —a systematic review
The effect of premorbid β-blocker exposure on clinical outcomes in patients with sepsis is not well characterized. We aimed to examine the association between premorbid β-blocker exposure and mortality in sepsis. (Source: Critical Care)
Source: Critical Care - September 4, 2019 Category: Intensive Care Authors: Kaiquan Tan, Martin Harazim, Benjamin Tang, Anthony Mclean and Marek Nalos Tags: Research Source Type: research

Time-based capnography detects ineffective triggering in mechanically ventilated children
(Source: Critical Care)
Source: Critical Care - September 4, 2019 Category: Intensive Care Authors: Robert G. T. Blokpoel, Alette A. Koopman, Jefta van Dijk, Frans H. C. de Jongh, Johannes G. M. Burgerhof and Martin C. J. Kneyber Tags: Letter Source Type: research

A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome
Our pilot study suggested that noninvasive ventilation (NIV) reduced the need for intubation compared with conventional administration of oxygen on patients with “early” stage of mild acute respiratory distres... (Source: Critical Care)
Source: Critical Care - September 4, 2019 Category: Intensive Care Authors: Hangyong He, Bing Sun, Lirong Liang, Yanming Li, He Wang, Luqing Wei, Guofeng Li, Shuliang Guo, Jun Duan, Yuping Li, Ying Zhou, Yusheng Chen, Hongru Li, Jingping Yang, Xiyuan Xu, Liqiang Song & hellip; Tags: Research Source Type: research

Confounding factors for the effect of misdiagnosis of site of infection on in-hospital mortality
(Source: Critical Care)
Source: Critical Care - September 3, 2019 Category: Intensive Care Authors: Kei Suzuki, Shinichiro Ohshimo and Nobuaki Shime Tags: Letter Source Type: research

Feedback function for capillary refilling time measurement device
(Source: Critical Care)
Source: Critical Care - September 3, 2019 Category: Intensive Care Authors: Masayoshi Shinozaki, Taka-aki Nakada, Rui Kawaguchi, Yuichiro Yoshimura, Toshiya Nakaguchi, Hideaki Haneishi and Shigeto Oda Tags: Letter Source Type: research

Endocan is a reliable biomarker during continuous renal replacement therapy
(Source: Critical Care)
Source: Critical Care - September 3, 2019 Category: Intensive Care Authors: Maxence Hureau, Alexandre Gaudet, Nathalie De Freitas Caires, Erika Parmentier, Julien Poissy, Thibault Duburcq, Philippe Lassalle and Daniel Mathieu Tags: Letter Source Type: research

Impact of post-sepsis cardiovascular complications on mortality in sepsis survivors: a population-based study
It remains unclear whether sepsis-related cardiovascular complications have an adverse impact on survival independent of pre-existing comorbidities. To investigate the survival impact of post-sepsis cardiovasc... (Source: Critical Care)
Source: Critical Care - September 2, 2019 Category: Intensive Care Authors: Meng-Huan Wu, Po-Yang Tsou, Yu-Hsun Wang, Meng-tse Gabriel Lee, Christin Chih Ting Chao, Wan-Chien Lee, Si-Huei Lee, Jiun-Ruey Hu, Jiunn-Yih Wu, Shy-Shin Chang and Chien-Chang Lee Tags: Research Source Type: research

Effect of dementia on the incidence, short-term outcomes, and resource utilization of invasive mechanical ventilation in the elderly: a nationwide population-based study
Though the prevalence of dementia among hospitalized patients is increasing, there is limited population data in Europe about the use of life-support measures such as invasive mechanical ventilation in these p... (Source: Critical Care)
Source: Critical Care - August 30, 2019 Category: Intensive Care Authors: Carmen Bouza, Gonzalo Mart ínez-Alés and Teresa López-Cuadrado Tags: Research Source Type: research