Appraisal of fungal infections during ECMO therapy
(Source: Critical Care)
Source: Critical Care - June 6, 2018 Category: Intensive Care Authors: Nicolas Mongardon, Oph élie Constant, Fabio Silvio Taccone and Eric Levesque Tags: Letter Source Type: research

Longing for better ultrasound-guided subclavian/axillary venous cannulation
(Source: Critical Care)
Source: Critical Care - June 5, 2018 Category: Intensive Care Authors: Gentle Sunder Shrestha Tags: Letter Source Type: research

Dexmedetomidine: the first new kid on the block for preventing cardiac surgery-associated acute kidney injury?
(Source: Critical Care)
Source: Critical Care - June 5, 2018 Category: Intensive Care Authors: Patrick M. Honore, David De Bels, Thierry Preseau and Herbert D. Spapen Tags: Letter Source Type: research

Identification of developing multiple organ failure in sepsis patients with low or moderate SOFA scores
(Source: Critical Care)
Source: Critical Care - June 5, 2018 Category: Intensive Care Authors: Gunnar Elke, Frank Bloos, Darius Cameron Wilson and Patrick Meybohm Tags: Letter Source Type: research

Are we near to the end of the standard dose of micafungin?
(Source: Critical Care)
Source: Critical Care - June 5, 2018 Category: Intensive Care Authors: Alexander Agrifoglio, Luc ía Cachafeiro, Eva Herrero, Manuel Sánchez and Abelardo García de Lorenzo Tags: Letter Source Type: research

FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care
Although high-flow nasal cannula therapy (HFNC) has become a popular mode of non-invasive respiratory support (NRS) in critically ill children, there are no randomised controlled trials (RCTs) comparing it wit... (Source: Critical Care)
Source: Critical Care - June 4, 2018 Category: Intensive Care Authors: Padmanabhan Ramnarayan, Paula Lister, Troy Dominguez, Parviz Habibi, Naomi Edmonds, Ruth R. Canter, Jerome Wulff, David A. Harrison, Paul M. Mouncey and Mark J. Peters Tags: Research Source Type: research

Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials
Restrictive red blood cell transfusion strategies remain controversial in patients undergoing cardiac surgery. We performed a meta-analysis to assess the prognostic benefits of restrictive red blood cell trans... (Source: Critical Care)
Source: Critical Care - May 31, 2018 Category: Intensive Care Authors: Qi-Hong Chen, Hua-Ling Wang, Lei Liu, Jun Shao, Jiangqian Yu and Rui-Qiang Zheng Tags: Review Source Type: research

Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS)
Sepsis is one of the main reasons for non-elective admission to pediatric intensive care units (PICUs), but little is known about determinants influencing outcome. We characterized children admitted with commu... (Source: Critical Care)
Source: Critical Care - May 31, 2018 Category: Intensive Care Authors: Navin P. Boeddha, Luregn J. Schlapbach, Gertjan J. Driessen, Jethro A. Herberg, Irene Rivero-Calle, Miriam Cebey-L ópez, Daniela S. Klobassa, Ria Philipsen, Ronald de Groot, David P. Inwald, Simon Nadel, Stéphane Paulus, Eleanor Pinnock, Fatou Secka, Su Tags: Research Source Type: research

Long-term use of selective digestive decontamination in an ICU highly endemic for bacterial resistance
We examined whether long-term use of selective digestive tract decontamination (SDD) was effective in reducing intensive care unit (ICU)-acquired infection and antibiotic consumption while decreasing colistin-... (Source: Critical Care)
Source: Critical Care - May 30, 2018 Category: Intensive Care Authors: Catalina S ánchez-Ramírez, Silvia Hípola-Escalada, Miriam Cabrera-Santana, María Adela Hernández-Viera, Liliana Caipe-Balcázar, Pedro Saavedra, Fernando Artiles-Campelo, Nayra Sangil-Monroy, Carlos Federico Lübbe-Vázquez and Sergio Ruiz-Santana Tags: Research Source Type: research

The role of adrenaline in cardiopulmonary resuscitation
Adrenaline has been used in the treatment of cardiac arrest for many years. It increases the likelihood of return of spontaneous circulation (ROSC), but some studies have shown that it impairs cerebral microci... (Source: Critical Care)
Source: Critical Care - May 29, 2018 Category: Intensive Care Authors: Christopher J. R. Gough and Jerry P. Nolan Tags: Review Source Type: research

Feasibility of optical coherence tomography angiography to assess changes in retinal microcirculation in ovine haemorrhagic shock
This study aimed to investigate the feasibility of optical coherence tomography angiography (OCT-A) for quantitative analysis of flow density to assess changes in retinal perfusion in an experimental model of ... (Source: Critical Care)
Source: Critical Care - May 29, 2018 Category: Intensive Care Authors: Maged Alnawaiseh, Christian Ertmer, Laura Seidel, Philip Helge Arnemann, Larissa Lahme, Tim-Gerald Kampmeier, Sebastian Willy Rehberg, Peter Heiduschka, Nicole Eter and Michael Hessler Tags: Research Source Type: research

Mechanical CPR: Who? When? How?
In cardiac arrest, high quality cardiopulmonary resuscitation (CPR) is a key determinant of patient survival. However, delivery of effective chest compressions is often inconsistent, subject to fatigue and pra... (Source: Critical Care)
Source: Critical Care - May 29, 2018 Category: Intensive Care Authors: Kurtis Poole, Keith Couper, Michael A. Smyth, Joyce Yeung and Gavin D. Perkins Tags: Review Source Type: research

Temporal biomarker profiles and their association with ICU acquired delirium: a cohort study
Neuroinflammation is thought to play an important role in the pathogenesis of ICU-acquired delirium, but the association between inflammatory and brain-specific proteins and ICU delirium is poor. We investigat... (Source: Critical Care)
Source: Critical Care - May 25, 2018 Category: Intensive Care Authors: Koen S. Simons, Mark van den Boogaard, Eva Hendriksen, Jelle Gerretsen, Johannes G. van der Hoeven, Peter Pickkers and Cornelis P. C. de Jager Tags: Research Source Type: research

Prolonged corticosteroid treatment in acute respiratory distress syndrome: impact on mortality and ventilator-free days
(Source: Critical Care)
Source: Critical Care - May 24, 2018 Category: Intensive Care Authors: Gianfranco Umberto Meduri, Bram Rochwerg, Djillali Annane and Stephen M. Pastores Tags: Letter Source Type: research

Acute lung injury: how to stabilize a broken lung
The pathophysiology of acute respiratory distress syndrome (ARDS) results in heterogeneous lung collapse, edema-flooded airways and unstable alveoli. These pathologic alterations in alveolar mechanics (i.e. dy... (Source: Critical Care)
Source: Critical Care - May 24, 2018 Category: Intensive Care Authors: Gary F. Nieman, Penny Andrews, Joshua Satalin, Kailyn Wilcox, Michaela Kollisch-Singule, Maria Madden, Hani Aiash, Sarah J. Blair, Louis A. Gatto and Nader M. Habashi Tags: Viewpoint Source Type: research

Effect of intensive glycaemic control on moderate hypoglycaemia and ICU length of stay in severe traumatic brain injury
(Source: Critical Care)
Source: Critical Care - May 23, 2018 Category: Intensive Care Authors: Rafael A. N úñez-Patiño, Andres Zorrilla-Vaca and Daniel Agustin Godoy Tags: Letter Source Type: research

Effect of postoperative goal-directed therapy in cancer patients undergoing high-risk surgery: a randomized clinical trial and meta-analysis
Perioperative goal-directed hemodynamic therapy (GDHT) has been advocated in high-risk patients undergoing noncardiac surgery to reduce postoperative morbidity and mortality. We hypothesized that using cardiac... (Source: Critical Care)
Source: Critical Care - May 23, 2018 Category: Intensive Care Authors: Aline Rejane Muller Gerent, Juliano Pinheiro Almeida, Evgeny Fominskiy, Giovanni Landoni, Gisele Queiroz de Oliveira, Stephanie Itala Rizk, Julia Tizue Fukushima, Claudia Marques Simoes, Ulysses Ribeiro Jr, Clarice Lee Park, Rosana Ely Nakamura, Rafael Al Tags: Research Source Type: research

Acetylcholine receptor antagonists in acute respiratory distress syndrome: much more than muscle relaxants
Acetylcholine receptor antagonists have been shown to improve outcome in patients with severe acute respiratory distress syndrome. However, it is incompletely understood how these agents improve outcome. In th... (Source: Critical Care)
Source: Critical Care - May 22, 2018 Category: Intensive Care Authors: Diana Jansen, Heder de Vries and Leo M. A. Heunks Tags: Editorial Source Type: research

Incidence of hypotension according to the discontinuation order of vasopressors in the management of septic shock: a prospective randomized trial (DOVSS)
Vasopressin (AVP) is commonly added to norepinephrine (NE) to reverse shock in patients with sepsis. However, there are no data to support the appropriate strategy of vasopressor tapering in patients on concom... (Source: Critical Care)
Source: Critical Care - May 21, 2018 Category: Intensive Care Authors: Kyeongman Jeon, Jae-Uk Song, Chi Ryang Chung, Jeong Hoon Yang and Gee Young Suh Tags: Research Source Type: research

Metabolic profiles in community-acquired pneumonia: developing assessment tools for disease severity
This study aimed to determine whether community-acquired pneumonia (CAP) had a metabolic profile and whether this profile can be used for disease severity assessment. (Source: Critical Care)
Source: Critical Care - May 14, 2018 Category: Intensive Care Authors: Pu Ning, Yali Zheng, Qiongzhen Luo, Xiaohui Liu, Yu Kang, Yan Zhang, Rongbao Zhang, Yu Xu, Donghong Yang, Wen Xi, Keqiang Wang, Yusheng Chen, Shuchang An and Zhancheng Gao Tags: Research Source Type: research

Ramped position, an uncertain future
(Source: Critical Care)
Source: Critical Care - May 13, 2018 Category: Intensive Care Authors: Luigi Vetrugno, Daniele Orso and Tiziana Bove Tags: Letter Source Type: research

Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia
This study aimed to evaluate the accuracy of procalcitonin (PCT) serum concentrations to diagnose Gram-negative bacteremia and the association of PCT serum concentrations with more specific pathogens and the f... (Source: Critical Care)
Source: Critical Care - May 13, 2018 Category: Intensive Care Authors: Daniel O. Thomas-R üddel, Bernhard Poidinger, Matthias Kott, Manfred Weiss, Konrad Reinhart and Frank Bloos Tags: Research Source Type: research

Experience of using beta-D-glucan assays in the intensive care unit
(Source: Critical Care)
Source: Critical Care - May 12, 2018 Category: Intensive Care Authors: A. Dagens, N. Mughal, A. Sisson and L. S. P. Moore Tags: Letter Source Type: research

TIMP-2/IGFBP7 predicts acute kidney injury in out-of-hospital cardiac arrest survivors
Acute kidney injury (AKI) is a common complication after cardiopulmonary resuscitation (CPR) and predicts in-hospital mortality. To which extent post-resuscitation disease or the initial event of cardiac arres... (Source: Critical Care)
Source: Critical Care - May 12, 2018 Category: Intensive Care Authors: Christoph Adler, Tobias Heller, Felix Schregel, Henning Hagmann, Martin Hellmich, Joana Adler and Hannes Reuter Tags: Research Source Type: research

Pulmonary vein signal in mitral regurgitation
(Source: Critical Care)
Source: Critical Care - May 11, 2018 Category: Intensive Care Authors: Tim Balthazar, Bart Jacobs and Jens-Uwe Voigt Tags: Letter Source Type: research

Clinical chronobiology: a timely consideration in critical care medicine
A fundamental aspect of human physiology is its cyclical nature over a 24-h period, a feature conserved across most life on Earth. Organisms compartmentalise processes with respect to time in order to promote ... (Source: Critical Care)
Source: Critical Care - May 11, 2018 Category: Intensive Care Authors: Helen McKenna, Gijsbertus T. J. van der Horst, Irwin Reiss and Daniel Martin Tags: Review Source Type: research

The choice of a postpyloric tube and the patient ’s position in our procedure: A response
(Source: Critical Care)
Source: Critical Care - May 10, 2018 Category: Intensive Care Authors: Bei Hu, Bo Lv and Chunbo Chen Tags: Letter Source Type: research

Feasibility and safety of low-flow extracorporeal CO2 removal managed with a renal replacement platform to enhance lung-protective ventilation of patients with mild-to-moderate ARDS
Extracorporeal carbon-dioxide removal (ECCO2R) might allow ultraprotective mechanical ventilation with lower tidal volume (VT) ( (Source: Critical Care)
Source: Critical Care - May 10, 2018 Category: Intensive Care Authors: Matthieu Schmidt, Samir Jaber, Elie Zogheib, Thomas Godet, Gilles Capellier and Alain Combes Tags: Research Source Type: research

Impact of flow and temperature on patient comfort during respiratory support by high-flow nasal cannula
In this study, we tested whether higher temperature and flow decrease... (Source: Critical Care)
Source: Critical Care - May 9, 2018 Category: Intensive Care Authors: Tommaso Mauri, Alessandro Galazzi, Filippo Binda, Laura Masciopinto, Nadia Corcione, Eleonora Carlesso, Marta Lazzeri, Elena Spinelli, Daniela Tubiolo, Carlo Alberto Volta, Ileana Adamini, Antonio Pesenti and Giacomo Grasselli Tags: Research Source Type: research

High-frequency oscillatory ventilation guided by transpulmonary pressure in acute respiratory syndrome: an experimental study in pigs
Recent clinical studies have not shown an overall benefit of high-frequency oscillatory ventilation (HFOV), possibly due to injurious or non-individualized HFOV settings. We compared conventional HFOV (HFOVcon) s... (Source: Critical Care)
Source: Critical Care - May 9, 2018 Category: Intensive Care Authors: Philipp Klapsing, Onnen Moerer, Christoph Wende, Peter Herrmann, Michael Quintel, Annalen Bleckmann and Jan Florian Heuer Tags: Research Source Type: research

Sepsis is a preventable public health problem
There is a paradigm shift happening for sepsis. Sepsis is no longer solely conceptualized as problem of individual patients treated in emergency departments and intensive care units but also as one that is add... (Source: Critical Care)
Source: Critical Care - May 6, 2018 Category: Intensive Care Authors: Jordan A. Kempker, Henry E. Wang and Greg S. Martin Tags: Commentary Source Type: research

Delirium prediction in the intensive care unit: comparison of two delirium prediction models
Accurate prediction of delirium in the intensive care unit (ICU) may facilitate efficient use of early preventive strategies and stratification of ICU patients by delirium risk in clinical research, but the op... (Source: Critical Care)
Source: Critical Care - May 5, 2018 Category: Intensive Care Authors: Annelies Wassenaar, Lisette Schoonhoven, John W. Devlin, Frank M. P. van Haren, Arjen J. C. Slooter, Philippe G. Jorens, Mathieu van der Jagt, Koen S. Simons, Ingrid Egerod, Lisa D. Burry, Albertus Beishuizen, Joaquim Matos, A. Rogier T. Donders, Peter Pi Tags: Research Source Type: research

Development and validation of a pre-hospital “Red Flag” alert for activation of intra-hospital haemorrhage control response in blunt trauma
This study aime... (Source: Critical Care)
Source: Critical Care - May 5, 2018 Category: Intensive Care Authors: Sophie Rym Hamada, Anne Rosa, Tobias Gauss, Jean-Philippe Desclefs, Mathieu Raux, Anatole Harrois, Arnaud Follin, Fabrice Cook, Mathieu Boutonnet, Arie Attias, Sylvain Ausset, Mathieu Boutonnet, Gilles Dhonneur, Jacques Duranteau, Olivier Langeron, Cather Tags: Research Source Type: research

Implications for paediatric shock management in resource-limited settings: a perspective from the FEAST trial
Although the African “Fluid Expansion as Supportive therapy” (FEAST) trial showed fluid resuscitation was harmful in children with severe febrile illness managed in resource-limited hospitals, the most recent ... (Source: Critical Care)
Source: Critical Care - May 4, 2018 Category: Intensive Care Authors: Kirsty Anne Houston, Elizabeth C. George and Kathryn Maitland Tags: Research Source Type: research

Pathophysiology, echocardiographic evaluation, biomarker findings, and prognostic implications of septic cardiomyopathy: a review of the literature
Sepsis is a common condition encountered by emergency and critical care physicians, with significant costs, both economic and human. Myocardial dysfunction in sepsis is a well-recognized but poorly understood ... (Source: Critical Care)
Source: Critical Care - May 4, 2018 Category: Intensive Care Authors: Robert R. Ehrman, Ashley N. Sullivan, Mark J. Favot, Robert L. Sherwin, Christian A. Reynolds, Aiden Abidov and Phillip D. Levy Tags: Review Source Type: research

Gut –kidney crosstalk in septic acute kidney injury
Sepsis is the leading cause of acute kidney injury (AKI) in the intensive care unit (ICU). Septic AKI is a complex and multifactorial process that is incompletely understood. During sepsis, the disruption of t... (Source: Critical Care)
Source: Critical Care - May 3, 2018 Category: Intensive Care Authors: Jingxiao Zhang, Ghada Ankawi, Jian Sun, Kumar Digvijay, Yongjie Yin, Mitchell H. Rosner and Claudio Ronco Tags: Review Source Type: research

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial
Intravenous fluids may contribute to lower haemoglobin levels in patients with septic shock. We sought to determine the relationship between the changes in haemoglobin concentration and the volume of intraveno... (Source: Critical Care)
Source: Critical Care - May 3, 2018 Category: Intensive Care Authors: Matthew J. Maiden, Mark E. Finnis, Sandra Peake, Simon McRae, Anthony Delaney, Michael Bailey and Rinaldo Bellomo Tags: Research Source Type: research

The impact of blood type O on mortality of severe trauma patients: a retrospective observational study
In this study, we evaluated the impact of the dif... (Source: Critical Care)
Source: Critical Care - May 2, 2018 Category: Intensive Care Authors: Wataru Takayama, Akira Endo, Hazuki Koguchi, Momoko Sugimoto, Kiyoshi Murata and Yasuhiro Otomo Tags: Research Source Type: research

Best PEEP trials are dependent on tidal volume
Determining the optimal positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome remains an area of active investigation. Most trials individualizing PEEP optimize one physi... (Source: Critical Care)
Source: Critical Care - May 2, 2018 Category: Intensive Care Authors: Andrew C. McKown, Matthew W. Semler and Todd W. Rice Tags: Letter Source Type: research

6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice
Increased vascular permeability is a pathophysiological hallmark of sepsis and results in increased transcapillary leakage of plasma fluid, hypovolemia, and interstitial edema formation. 6% hydroxyethyl starch... (Source: Critical Care)
Source: Critical Care - May 1, 2018 Category: Intensive Care Authors: Andreas Margraf, Jan M. Herter, Katharina K ühne, Anika Stadtmann, Thomas Ermert, Manuel Wenk, Melanie Meersch, Hugo Van Aken, Alexander Zarbock and Jan Rossaint Tags: Research Source Type: research

Comparison of exercise intensity during four early rehabilitation techniques in sedated and ventilated patients in ICU: a randomised cross-over trial
In the ICU, out-of-bed rehabilitation is often delayed and in-bed exercises are generally low-intensity. Since the majority of rehabilitation is carried out in bed, it is essential to carry out the exercises t... (Source: Critical Care)
Source: Critical Care - April 27, 2018 Category: Intensive Care Authors: Cl ément Medrinal, Yann Combret, Guillaume Prieur, Aurora Robledo Quesada, Tristan Bonnevie, Francis Edouard Gravier, Elise Dupuis Lozeron, Eric Frenoy, Olivier Contal and Bouchra Lamia Tags: Research Source Type: research

Ultrasound-assessed diaphragmatic impairment is a predictor of outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease undergoing noninvasive ventilation
Ultrasound (US) evaluation of diaphragmatic dysfunction (DD) has proved to be a reliable technique in critical care. In this single-center prospective study, we investigated the impact of US-assessed DD on non... (Source: Critical Care)
Source: Critical Care - April 27, 2018 Category: Intensive Care Authors: Alessandro Marchioni, Ivana Castaniere, Roberto Tonelli, Riccardo Fantini, Matteo Fontana, Luca Tabb ì, Andrea Viani, Francesco Giaroni, Valentina Ruggieri, Stefania Cerri and Enrico Clini Tags: Research Source Type: research

Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery
Acute kidney injury (AKI) after cardiovascular surgery is a serious complication. Little is known about the ability of novel biomarkers in combination with clinical risk scores for prediction of advanced AKI. (Source: Critical Care)
Source: Critical Care - April 26, 2018 Category: Intensive Care Authors: Jian-Jhong Wang, Nai-Hsin Chi, Tao-Min Huang, Rory Connolly, Liang Wen Chen, Shih-Chieh Jeff Chueh, Wei-Chih Kan, Chih-Cheng Lai, Vin-Cent Wu, Ji-Tseng Fang, Tzong-Shinn Chu and Kwan-Dun Wu Tags: Research Source Type: research

Distinct T-helper cell responses to Staphylococcus aureus bacteremia reflect immunologic comorbidities and correlate with mortality
The dysregulated host immune response that defines sepsis varies as a function of both the immune status of the host and the distinct nature of the pathogen. The degree to which immunocompromising comorbiditie... (Source: Critical Care)
Source: Critical Care - April 25, 2018 Category: Intensive Care Authors: Jared A. Greenberg, Cara L. Hrusch, Mohammad R. Jaffery, Michael Z. David, Robert S. Daum, Jesse B. Hall, John P. Kress, Anne I. Sperling and Philip A. Verhoef Tags: Research Source Type: research

Inclusion and definition of acute renal dysfunction in critically ill patients in randomized controlled trials: a systematic review
In evidence-based medicine, multicenter, prospective, randomized controlled trials (RCTs) are the gold standard for evaluating treatment benefits and ensuring the effectiveness of interventions. Patient-center... (Source: Critical Care)
Source: Critical Care - April 24, 2018 Category: Intensive Care Authors: Rogerio da Hora Passos, Joao Gabriel Rosa Ramos, Andr é Gobatto, Juliana Caldas, Etienne Macedo and Paulo Benigno Batista Tags: Research Source Type: research

Evaluation of a real-time PCR assay for detection and quantification of bacterial DNA directly in blood of preterm neonates with suspected late-onset sepsis
Rapid and accurate diagnosis of neonatal sepsis is highly warranted because of high associated morbidity and mortality. The aim of this study was to evaluate the performance of a novel multiplex PCR assay for ... (Source: Critical Care)
Source: Critical Care - April 22, 2018 Category: Intensive Care Authors: Marre van den Brand, Frank A. M. van den Dungen, Martine P. Bos, Mirjam M. van Weissenbruch, A. Marceline van Furth, Annemieke de Lange, Anna Rubenjan, Remco P. H. Peters and Paul H. M. Savelkoul Tags: Research Source Type: research

Resuscitative endovascular balloon occlusion of the aorta performed by emergency physicians for traumatic hemorrhagic shock: a case series from Japanese emergency rooms
Resuscitative endovascular balloon occlusion of the aorta (REBOA), which has been increasingly used for the management of hemorrhagic shock, is a less invasive strategy for the management of patients with very... (Source: Critical Care)
Source: Critical Care - April 21, 2018 Category: Intensive Care Authors: Ryota Sato, Akira Kuriyama, Rei Takaesu, Nobuhiro Miyamae, Wataru Iwanaga, Hayato Tokuda and Takehiro Umemura Tags: Research Source Type: research

Blocking soluble guanylate cyclase could be the present and future of NO/cGMP inhibition for vasoplegia treatment
(Source: Critical Care)
Source: Critical Care - April 20, 2018 Category: Intensive Care Authors: Paulo Roberto Barbosa Evora Tags: Letter Source Type: research

Worldwide audit of blood transfusion practice in critically ill patients
The aim was to describe transfusion practice in critically ill patients at an international level and evaluate the effects of red blood cell (RBC) transfusion on outcomes in these patients. (Source: Critical Care)
Source: Critical Care - April 19, 2018 Category: Intensive Care Authors: Jean-Louis Vincent, Ulrich Jaschinski, Xavier Wittebole, Jean-Yves Lefrant, Stephan M. Jakob, Ghaleb A. Almekhlafi, Tommaso Pellis, Swagata Tripathy, Paolo N. Rubatto Birri and Yasser Sakr Tags: Research Source Type: research

Early versus standard initiation of renal replacement therapy in furosemide stress test non-responsive acute kidney injury patients (the FST trial)
The timing of initiation of renal replacement therapy (RRT) in severe acute kidney injury (AKI) remains controversial, with early initiation resulting in unnecessary therapy for some patients while expectant t... (Source: Critical Care)
Source: Critical Care - April 19, 2018 Category: Intensive Care Authors: Nuttha Lumlertgul, Sadudee Peerapornratana, Thananda Trakarnvanich, Wanjak Pongsittisak, Kajbundit Surasit, Anan Chuasuwan, Pleumjit Tankee, Khajohn Tiranathanagul, Kearkiat Praditpornsilpa, Kriang Tungsanga, Somchai Eiam-Ong, John A. Kellum and Nattachai Tags: Research Source Type: research