Chest radiography versus lung ultrasound for identification of acute respiratory distress syndrome: a retrospective observational study
Lung ultrasound may be a reasonable alternative to chest radiography for the identification of acute respiratory distress syndrome (ARDS), but the diagnostic performance of lung ultrasound for ARDS is uncertai... (Source: Critical Care)
Source: Critical Care - August 18, 2018 Category: Intensive Care Authors: Kay Choong See, Venetia Ong, Yi Lin Tan, Juliet Sahagun and Juvel Taculod Tags: Research Source Type: research

Efficacy of polymyxin B hemoperfusion in and beyond septic shock: is an “endotoxin severity score” needed?
(Source: Critical Care)
Source: Critical Care - August 17, 2018 Category: Intensive Care Authors: Patrick M. Honore, David De Bels, Thierry Preseau, Sebastien Redant and Herbert D. Spapen Tags: Letter Source Type: research

Hemodynamic management of critically ill burn patients: an international survey
(Source: Critical Care)
Source: Critical Care - August 17, 2018 Category: Intensive Care Authors: Sabri Soussi, Mette M. Berger, Kirsten Colpaert, Martin W. D ünser, Anne Berit Guttormsen, Nicole P. Juffermans, Paul Knape, Guniz Koksal, Athina Lavrentieva, Thomas Leclerc, José A. Lorente, Ignacio Martin-Loeches, Philipp Metnitz, Olivier Pantet, Paol Tags: Letter Source Type: research

Functional outcomes in adults with tuberculous meningitis admitted to the ICU: a multicenter cohort study
Tuberculous meningitis (TBM) is a devastating infection in tuberculosis endemic areas with limited access to intensive care. Functional outcomes of severe adult TBM patients admitted to the ICU in nonendemic a... (Source: Critical Care)
Source: Critical Care - August 17, 2018 Category: Intensive Care Authors: Marie Cantier, Adeline Morisot, Emmanuel Gu érot, Bruno Megarbane, Keyvan Razazi, Damien Contou, Eric Mariotte, Emmanuel Canet, Etienne De Montmollin, Vincent Dubée, Eric Boulet, Stéphane Gaudry, Guillaume Voiriot, Julien Mayaux, Frédéric Pène, Math Tags: Research Source Type: research

Histidine-rich glycoprotein as an excellent biomarker for sepsis and beyond
Sepsis remains a critical problem with high morbidity and mortality worldwide. One of the problems we have in critical care is the need to find a good biomarker of sepsis to determine the existence of bacteria... (Source: Critical Care)
Source: Critical Care - August 17, 2018 Category: Intensive Care Authors: Masahiro Nishibori, Hidenori Wake and Hiroshi Morimatsu Tags: Editorial Source Type: research

Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries
To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS... (Source: Critical Care)
Source: Critical Care - August 17, 2018 Category: Intensive Care Authors: Toshikazu Abe, Fabiana Madotto, T ài Pham, Isao Nagata, Masatoshi Uchida, Nanako Tamiya, Kiyoyasu Kurahashi, Giacomo Bellani and John G. Laffey Tags: Research Source Type: research

Adjuvant vitamin C in cardiac arrest patients undergoing renal replacement therapy: an appeal for a higher high-dose
(Source: Critical Care)
Source: Critical Care - August 16, 2018 Category: Intensive Care Authors: Patrick M. Honore, David De Bels, Thierry Preseau, Sebastien Redant, Rachid Attou and Herbert D. Spapen Tags: Letter Source Type: research

Could ultrasound-guided internal jugular vein catheter insertion replace the use of chest X-ray?
(Source: Critical Care)
Source: Critical Care - August 16, 2018 Category: Intensive Care Authors: William F. Amaya-Zu ñiga and Fernando Raffán-Sanabria Tags: Letter Source Type: research

Bundle of care taking into account time to improve long-term outcome after cardiac arrest
(Source: Critical Care)
Source: Critical Care - August 15, 2018 Category: Intensive Care Authors: R. Jouffroy and B. Vivien Tags: Letter Source Type: research

Airway and ventilation management during cardiopulmonary resuscitation and after successful resuscitation
After cardiac arrest a combination of basic and advanced airway and ventilation techniques are used during cardiopulmonary resuscitation (CPR) and after a return of spontaneous circulation (ROSC). The optimal ... (Source: Critical Care)
Source: Critical Care - August 15, 2018 Category: Intensive Care Authors: Christopher Newell, Scott Grier and Jasmeet Soar Tags: Review Source Type: research

Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials
The clinical utility of serum procalcitonin levels in guiding antibiotic treatment decisions in patients with sepsis remains unclear. This patient-level meta-analysis based on 11 randomized trials investigates... (Source: Critical Care)
Source: Critical Care - August 15, 2018 Category: Intensive Care Authors: Yannick Wirz, Marc A. Meier, Lila Bouadma, Charles E. Luyt, Michel Wolff, Jean Chastre, Florence Tubach, Stefan Schroeder, Vandack Nobre, Djillali Annane, Konrad Reinhart, Pierre Damas, Maarten Nijsten, Arezoo Shajiei, Dylan W. deLange, Rodrigo O. Deliber Tags: Review Source Type: research

Platelet storage duration and its clinical and transfusion outcomes: a systematic review
Platelets (PLTs) are usually stored for up to 5 days prior to transfusion, although in some blood services the storage period is extended to 7 days. During storage, changes occur in both PLT and storage medium... (Source: Critical Care)
Source: Critical Care - August 5, 2018 Category: Intensive Care Authors: C écile Aubron, Andrew W. J. Flint, Yves Ozier and Zoe McQuilten Tags: Review Source Type: research

Effects of hyperoxia on vascular tone in animal models: systematic review and meta-analysis
Arterial hyperoxia may induce vasoconstriction and reduce cardiac output, which is particularly undesirable in patients who already have compromised perfusion of vital organs. Due to the inaccessibility of vit... (Source: Critical Care)
Source: Critical Care - August 4, 2018 Category: Intensive Care Authors: Bob Smit, Yvo M. Smulders, Etto C. Eringa, Heleen M. Oudemans - van Straaten, Armand R. J. Girbes, Kimberley E. Wever, Carlijn R. Hooijmans and Angelique M. E. Spoelstra - de Man Tags: Research Source Type: research

Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis
Sepsis-induced myocardial dysfunction is associated with poor outcomes, but traditional measurements of systolic function such as left ventricular ejection fraction (LVEF) do not directly correlate with progno... (Source: Critical Care)
Source: Critical Care - August 4, 2018 Category: Intensive Care Authors: F. Sanfilippo, C. Corredor, N. Fletcher, L. Tritapepe, F. L. Lorini, A. Arcadipane, A. Vieillard-Baron and M. Cecconi Tags: Research Source Type: research

A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit
Acute kidney injury (AKI) is a common complication of critical illness and is associated with worse outcomes. However, the influence of deterioration or improvement in renal function on clinical outcomes is un... (Source: Critical Care)
Source: Critical Care - August 3, 2018 Category: Intensive Care Authors: Esther Peters, Massimo Antonelli, Xavier Wittebole, Rahul Nanchal, Bruno Fran çois, Yasser Sakr, Jean-Louis Vincent and Peter Pickkers Tags: Research Source Type: research

Validation of carbon dioxide production (VCO2) as a tool to calculate resting energy expenditure (REE) in mechanically ventilated critically ill patients: a retrospective observational study
Indirect calorimetry (IC) measurement is considered the gold standard for the assessment of resting energy expenditure (REE). It is based on the measurement of oxygen and carbon dioxide consumption (VO2 and VCO2,... (Source: Critical Care)
Source: Critical Care - August 3, 2018 Category: Intensive Care Authors: I. Kagan, O. Zusman, I. Bendavid, M. Theilla, J. Cohen and P. Singer Tags: Research Source Type: research

Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis
The association between corticosteroid use and intensive care unit (ICU)-acquired weakness remains unclear. We evaluated the relationship between corticosteroid use and ICU-acquired weakness in critically ill ... (Source: Critical Care)
Source: Critical Care - August 3, 2018 Category: Intensive Care Authors: Tao Yang, Zhiqiang Li, Li Jiang and Xiuming Xi Tags: Research Source Type: research

Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas
There is considerable physiological and clinical evidence of harm and increased risk of death associated with dysglycemia in critical care. However, glycemic control (GC) currently leads to increased hypoglyce... (Source: Critical Care)
Source: Critical Care - August 2, 2018 Category: Intensive Care Authors: J. Geoffrey Chase, Thomas Desaive, Julien Bohe, Miriam Cnop, Christophe De Block, Jan Gunst, Roman Hovorka, Pierre Kalfon, James Krinsley, Eric Renard and Jean-Charles Preiser Tags: Review Source Type: research

High-flow nasal cannula oxygen therapy decreases postextubation neuroventilatory drive and work of breathing in patients with chronic obstructive pulmonary disease
In this study, we compared the effects of HFNC and conventional lo... (Source: Critical Care)
Source: Critical Care - August 2, 2018 Category: Intensive Care Authors: Rosa Di mussi, Savino Spadaro, Tania Stripoli, Carlo Alberto Volta, Paolo Trerotoli, Paola Pierucci, Francesco Staffieri, Francesco Bruno, Luigi Camporota and Salvatore Grasso Tags: Research Source Type: research

Value and mechanisms of EEG reactivity in the prognosis of patients with impaired consciousness: a systematic review
Electroencephalography (EEG) is a well-established tool for assessing brain function that is available at the bedside in the intensive care unit (ICU). This review aims to discuss the relevance of electroencep... (Source: Critical Care)
Source: Critical Care - August 2, 2018 Category: Intensive Care Authors: Eric Azabou, Vincent Navarro, Nathalie Kubis, Martine Gavaret, Nicholas Heming, Alain Cariou, Djillali Annane, Fr éderic Lofaso, Lionel Naccache and Tarek Sharshar Tags: Research Source Type: research

Erythrocyte P2X1 receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis
Pore-forming proteins released from bacteria or formed as result of complement activation are known to produce severe cell damage. Inhibition of purinergic P2X receptors markedly reduces damage inflicted by cy... (Source: Critical Care)
Source: Critical Care - August 2, 2018 Category: Intensive Care Authors: Steen K. Fagerberg, Parth Patel, Lars W. Andersen, Xiaowen Lui, Michael W. Donnino and Helle A. Praetorius Tags: Research Source Type: research

Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis
Decompressive laparotomy has been advised as potential treatment for abdominal compartment syndrome (ACS) when medical management fails; yet, the effect on parameters of organ function differs markedly in the ... (Source: Critical Care)
Source: Critical Care - July 25, 2018 Category: Intensive Care Authors: Lana Van Damme and Jan J. De Waele Tags: Research Source Type: research

Specific dynamic of serum procalcitonin in critically ill patients affected by Gram-negative bacilli septic thrombophlebitis
(Source: Critical Care)
Source: Critical Care - July 23, 2018 Category: Intensive Care Authors: Martina Spaziante, Giancarlo Ceccarelli, Samir Al Moghazi, Francesco Alessandri and Mario Venditti Tags: Letter Source Type: research

The kinetic glomerular filtration rate is not interchangeable with measured creatinine clearance for prediction of piperacillin underexposure in critically ill patients with augmented renal clearance
(Source: Critical Care)
Source: Critical Care - July 23, 2018 Category: Intensive Care Authors: C édric Carrié, Sébastien Rubin, Pierre Sioniac, Dominique Breilh and Matthieu Biais Tags: Letter Source Type: research

Plasma myeloperoxidase-conjugated DNA level predicts outcomes and organ dysfunction in patients with septic shock
Recent studies have suggested that excessive formation of neutrophil extracellular traps (NETs) plays a critical role in the pathogenesis of sepsis. Although elevation of the plasma level of cell-free DNA (cf-... (Source: Critical Care)
Source: Critical Care - July 13, 2018 Category: Intensive Care Authors: Yuki Maruchi, Masanobu Tsuda, Hisatake Mori, Nobuyoshi Takenaka, Takayoshi Gocho, Muhammad A. Huq and Naoshi Takeyama Tags: Research Source Type: research

Clinical characteristics and prognosis of bacteraemia during postoperative intra-abdominal infections
Bloodstream infections of abdominal origin are usually associated with poor prognosis. We assessed the clinical and microbiological characteristics of critically ill patients admitted to the intensive care uni... (Source: Critical Care)
Source: Critical Care - July 7, 2018 Category: Intensive Care Authors: Adel Alqarni, Elie Kantor, Nathalie Grall, Sebastien Tanaka, Nathalie Zappella, Mathieu Godement, Lara Ribeiro-Parenti, Alexy Tran-Dinh and Philippe Montravers Tags: Research Source Type: research

Emergency Department disposition decisions and associated mortality and costs in ICU patients with suspected infection
Following emergency department (ED) assessment, patients with infection may be directly admitted to the intensive care unit (ICU) or alternatively admitted to hospital wards or sent home. Those admitted to the... (Source: Critical Care)
Source: Critical Care - July 6, 2018 Category: Intensive Care Authors: Shannon M. Fernando, Bram Rochwerg, Peter M. Reardon, Kednapa Thavorn, Andrew J. E. Seely, Jeffrey J. Perry, Douglas P. Barnaby, Peter Tanuseputro and Kwadwo Kyeremanteng Tags: Research Source Type: research

Definitions and pathophysiology of vasoplegic shock
Vasoplegia is the syndrome of pathological low systemic vascular resistance, the dominant clinical feature of which is reduced blood pressure in the presence of a normal or raised cardiac output. The vasoplegi... (Source: Critical Care)
Source: Critical Care - July 6, 2018 Category: Intensive Care Authors: Simon Lambden, Ben C. Creagh-Brown, Julie Hunt, Charlotte Summers and Lui G. Forni Tags: Review Source Type: research

Early application of continuous high-volume haemofiltration can reduce sepsis and improve the prognosis of patients with severe burns
In the early stage of severe burn, patients often exhibit a high level of inflammatory mediators in blood and are likely to develop sepsis. High-volume haemofiltration (HVHF) can eliminate these inflammatory m... (Source: Critical Care)
Source: Critical Care - July 6, 2018 Category: Intensive Care Authors: Bo You, Yu Long Zhang, Gao Xing Luo, Yong Ming Dang, Bei Jiang, Guang Tao Huang, Xin Zhu Liu, Zi Chen Yang, Yu Chen, Jing Chen, Zhi Qiang Yuan, Su Peng Yin and Yi Zhi Peng Tags: Research Source Type: research

Use of ECMO in ARDS: does the EOLIA trial really help?
(Source: Critical Care)
Source: Critical Care - July 5, 2018 Category: Intensive Care Authors: Luciano Gattinoni, Francesco Vasques and Michael Quintel Tags: Editorial Source Type: research

Gastric versus postpyloric enteral nutrition in elderly patients (age ≥ 75 years) on mechanical ventilation: a single-center randomized trial
The risk of ventilator-associated pneumonia (VAP) is reduced when postpyloric enteral nutrition (EN) is administered compared to when gastric EN is administered in specific populations. In the present study, w... (Source: Critical Care)
Source: Critical Care - July 5, 2018 Category: Intensive Care Authors: Youfeng Zhu, Haiyan Yin, Rui Zhang, Xiaoling Ye and Jianrui Wei Tags: Research Source Type: research

Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study
Whether a restrictive strategy for red blood cell (RBC) transfusion is applied to patients with aneurysmal subarachnoid hemorrhage (aSAH) is unclear. To inform the design and conduct of a future clinical trial... (Source: Critical Care)
Source: Critical Care - July 4, 2018 Category: Intensive Care Authors: Shane W. English, Micha ël Chassé, Alexis F. Turgeon, François Lauzier, Donald Griesdale, Allan Garland, Dean Fergusson, Ryan Zarychanski, Carl van Walraven, Kaitlyn Montroy, Jennifer Ziegler, Raphael Dupont-Chouinard, Raphaëlle Carignan, Andy Dhaliwa Tags: Research Source Type: research

Postoperative cellular stress in the kidney is associated with an early systemic γδ T-cell immune cell response
Basic science data suggest that acute kidney injury (AKI) induced by ischemia-reperfusion injury (IRI) is an inflammatory process involving the adaptive immune response. Little is known about the T-cell contri... (Source: Critical Care)
Source: Critical Care - July 4, 2018 Category: Intensive Care Authors: Ivan G öcze, Katharina Ehehalt, Florian Zeman, Paloma Riquelme, Karin Pfister, Bernhard M. Graf, Thomas Bein, Edward K. Geissler, Piotr Kasprzak, Hans J. Schlitt, John A. Kellum, James A. Hutchinson, Elke Eggenhofer and Philipp Renner Tags: Research Source Type: research

Improved empirical antibiotic treatment of sepsis after an educational intervention: the ABISS-Edusepsis study
Early appropriate antibiotic treatment is essential in sepsis. We aimed to evaluate the impact of a multifaceted educational intervention to improve antibiotic treatment. We hypothesized that the intervention ... (Source: Critical Care)
Source: Critical Care - June 22, 2018 Category: Intensive Care Authors: Ricard Ferrer, Mar ía Luisa Martínez, Gemma Gomà, David Suárez, Luis Álvarez-Rocha, María Victoria de la Torre, Gumersindo González, Rafael Zaragoza, Marcio Borges, Jesús Blanco, Eduardo Palencia Herrejón and Antonio Artigas Tags: Research Source Type: research

Flexible bronchoscopy-related safety in patients with severe ARDS
(Source: Critical Care)
Source: Critical Care - June 21, 2018 Category: Intensive Care Authors: A. Guillon, M.-A. Nay and T. Kamel Tags: Letter Source Type: research

Low b-value diffusion weighted imaging is promising in the diagnosis of brain death and hypoxic-ischemic injury secondary to cardiopulmonary arrest
Cardiorespiratory arrest can result in a spectrum of hypoxic ischemic brain injury leading to global hypoperfusion and brain death (BD). Because up to 40% of patients with BD are viable organ donors, avoiding ... (Source: Critical Care)
Source: Critical Care - June 20, 2018 Category: Intensive Care Authors: Miriam E. Peckham, Jeffrey S. Anderson, Ulrich A. Rassner, Lubdha M. Shah, Peter J. Hinckley, Adam de Havenon, Seong-Eun Kim and J. Scott McNally Tags: Research Source Type: research

Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial
There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial,... (Source: Critical Care)
Source: Critical Care - June 18, 2018 Category: Intensive Care Authors: Nicola Curry, Claire Foley, Henna Wong, Ana Mora, Elinor Curnow, Agne Zarankaite, Renate Hodge, Valerie Hopkins, Alison Deary, James Ray, Phil Moss, Matthew J. Reed, Suzanne Kellett, Ross Davenport and Simon Stanworth Tags: Research Source Type: research

Position of draining venous cannula in extracorporeal membrane oxygenation for respiratory and respiratory/circulatory support in adult patients
Extracorporeal membrane oxygenation (ECMO) is used in critically ill patients with severe pulmonary and/or cardiac failure. Blood is drained from the venous system and pumped through a membrane oxygenator wher... (Source: Critical Care)
Source: Critical Care - June 15, 2018 Category: Intensive Care Authors: B. Frenckner, M. Broman and M. Broom é Tags: Viewpoint Source Type: research

Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock
Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contr... (Source: Critical Care)
Source: Critical Care - June 15, 2018 Category: Intensive Care Authors: Anatole Harrois, Nicolas Grillot, Samy Figueiredo and Jacques Duranteau Tags: Research Source Type: research

Shock subtypes by left ventricular ejection fraction following out-of-hospital cardiac arrest
Post-resuscitation hemodynamic instability following out-of-hospital cardiac arrest (OHCA) may occur from myocardial dysfunction underlying cardiogenic shock and/or inflammation-mediated distributive shock. Di... (Source: Critical Care)
Source: Critical Care - June 15, 2018 Category: Intensive Care Authors: Ryan J. Anderson, Sayuri P. Jinadasa, Leeyen Hsu, Tiffany Bita Ghafouri, Sanjeev Tyagi, Jisha Joshua, Ariel Mueller, Daniel Talmor, Rebecca E. Sell and Jeremy R. Beitler Tags: Research Source Type: research

Predictors of health-related quality of life after burn injuries: a systematic review
This study aimed to systematically review predictors of HRQL ... (Source: Critical Care)
Source: Critical Care - June 14, 2018 Category: Intensive Care Authors: Inge Spronk, Catherine M. Legemate, Jan Dokter, Nancy E. E. van Loey, Margriet E. van Baar and Suzanne Polinder Tags: Review Source Type: research

The mechanism of action of the adrenomedullin-binding antibody adrecizumab
(Source: Critical Care)
Source: Critical Care - June 13, 2018 Category: Intensive Care Authors: Christopher Geven and Peter Pickkers Tags: Letter Source Type: research

Thrombocytopenia in the ICU: disseminated intravascular coagulation and thrombotic microangiopathies —what intensivists need to know
(Source: Critical Care)
Source: Critical Care - June 13, 2018 Category: Intensive Care Authors: Jean-Louis Vincent, Pedro Castro, Beverley J. Hunt, Achim J örres, Manuel Praga, Jose Rojas-Suarez and Eizo Watanabe Tags: Editorial Source Type: research

Very high intact-protein formula successfully provides protein intake according to nutritional recommendations in overweight critically ill patients: a double-blind randomized trial
Optimal energy and protein provision through enteral nutrition is essential for critically ill patients. However, in clinical practice, the intake achieved is often far below the recommended targets. Because n... (Source: Critical Care)
Source: Critical Care - June 12, 2018 Category: Intensive Care Authors: Arthur R. H. van Zanten, Laurent Petit, Jan De Waele, Hans Kieft, Janneke de Wilde, Peter van Horssen, Marianne Klebach and Zandrie Hofman Tags: Research Source Type: research

Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database
The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. (Source: Critical Care)
Source: Critical Care - June 12, 2018 Category: Intensive Care Authors: Andrea Cortegiani, Fabiana Madotto, Cesare Gregoretti, Giacomo Bellani, John G. Laffey, Tai Pham, Frank Van Haren, Antonino Giarratano, Massimo Antonelli, Antonio Pesenti and Giacomo Grasselli Tags: Research Source Type: research

Can nutritional interventions change major clinical outcomes?
(Source: Critical Care)
Source: Critical Care - June 8, 2018 Category: Intensive Care Authors: Sho Horikita, Masamitsu Sanui and Alan K. Lefor Tags: Letter Source Type: research

Acute kidney injury and mild therapeutic hypothermia in patients after cardiopulmonary resuscitation - a post hoc analysis of a prospective observational trial
The aim of this study was to investigate the influence of mild therapeutic hypothermia (MTH) on the incidence of and recovery from acute kidney injury (AKI). (Source: Critical Care)
Source: Critical Care - June 8, 2018 Category: Intensive Care Authors: Julia Hasslacher, Fabian Barbieri, Ulrich Harler, Hanno Ulmer, Lui G. Forni, Romuald Bellmann and Michael Joannidis Tags: Research Source Type: research

Antiepileptic drugs in critically ill patients
The incidence of seizures in intensive care units ranges from 3.3% to 34%. It is therefore often necessary to initiate or continue anticonvulsant drugs in this setting. When a new anticonvulsant is initiated, ... (Source: Critical Care)
Source: Critical Care - June 7, 2018 Category: Intensive Care Authors: Salia Farrokh, Pouya Tahsili-Fahadan, Eva K. Ritzl, John J. Lewin III and Marek A. Mirski Tags: Review Source Type: research

Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis
(Source: Critical Care)
Source: Critical Care - June 7, 2018 Category: Intensive Care Authors: Debasree Banerjee, Sean Monaghan, Runping Zhao, Thomas Walsh, Amy Palmisciano, Gary S. Phillips, Steven Opal and Mitchell M. Levy Tags: Letter Source Type: research

Albumin mass balance and kinetics in liver transplantation
In major abdominal surgery albumin is shifted from the circulation, presumably leaking into the interstitial space, contributing to a 30 –40% decrease in plasma albumin concentration. During and after liver tra... (Source: Critical Care)
Source: Critical Care - June 7, 2018 Category: Intensive Care Authors: Mariam Amouzandeh, Greg Nowak, Anna Januszkiewicz, Jan Wernerman, Olav Rooyackers and Åke Norberg Tags: Research Source Type: research