Effect of chest wall loading during supine and prone position in a critically ill covid-19 patient: a new strategy for ARDS?
(Source: Critical Care)
Source: Critical Care - December 20, 2021 Category: Intensive Care Authors: Sergio Lassola, Sara Miori, Andrea Sanna, Rocco Pace, Sandra Magnoni, Luigi Vetrugno and Michele Umbrello Tags: Commentary Source Type: research

Anti-influenza T cells in bronchoalveolar microenvironment of critically severe COVID-19 patients
(Source: Critical Care)
Source: Critical Care - December 20, 2021 Category: Intensive Care Authors: Ming Zheng Tags: Research Letter Source Type: research

Ventilator-associated pneumonia in critically-ill patients with COVID-19 in a setting of selective decontamination of the digestive tract
(Source: Critical Care)
Source: Critical Care - December 20, 2021 Category: Intensive Care Authors: Sinta B. van der Meer, Grace Figaroa, Peter H. J. van der Voort, Maarten W. Nijsten and Janesh Pillay Tags: Research Letter Source Type: research

A pilot study of trained ICU doulas providing early psychological support to critically ill patients
Over a third of critical illness survivors suffer from mental health problems following hospitalization. Memories of delusional experiences are a major risk factor. In this project, ICU doulas delivered a uniq... (Source: Critical Care)
Source: Critical Care - December 20, 2021 Category: Intensive Care Authors: Lioudmila V. Karnatovskaia, Katalin Varga, Alexander S. Niven, Phillip J. Schulte, Midhat Mujic, Ognjen Gajic, Brent A. Bauer, Matthew M. Clark, Roberto P. Benzo and Kemuel L. Philbrick Tags: Research Source Type: research

Dangers of hyperoxia
Oxygen (O2) toxicity remains a concern, particularly to the lung. This is mainly related to excessive production of reactive oxygen species (ROS). Supplemental O2, i.e. inspiratory O2 concentrations (FIO2)  > 0.21... (Source: Critical Care)
Source: Critical Care - December 19, 2021 Category: Intensive Care Authors: Mervyn Singer, Paul J. Young, John G. Laffey, Pierre Asfar, Fabio Silvio Taccone, Markus B. Skrifvars, Christian S. Meyhoff and Peter Radermacher Tags: Review Source Type: research

Impact of rewarming rate on interleukin-6 levels in patients with shockable cardiac arrest receiving targeted temperature management at 33 °C: the ISOCRATE pilot randomized controlled trial
While targeted temperature management (TTM) has been recommended in patients with shockable cardiac arrest (CA) and suggested in patients with non-shockable rhythms, few data exist regarding the impact of the ... (Source: Critical Care)
Source: Critical Care - December 17, 2021 Category: Intensive Care Authors: Jean-Baptiste Lascarrou, Elie Guichard, Jean Reignier, Am élie Le Gouge, Caroline Pouplet, Stéphanie Martin, Jean-Claude Lacherade and Gwenhael Colin Tags: Research Source Type: research

Correction to: The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients
(Source: Critical Care)
Source: Critical Care - December 17, 2021 Category: Intensive Care Authors: Antoni Torres, Anna Motos, Jordi Riera, Laia Fern ández-Barat, Adrián Ceccato, Raquel Pérez-Arnal, Dario García-Gasulla, Oscar Peñuelas, José Angel Lorente, Alejandro Rodriguez, David de Gonzalo-Calvo, Raquel Almansa, Albert Gabarrús, Rosario Mené Tags: Correction Source Type: research

Albumin and fibrinogen kinetics in sepsis: a prospective observational study
The measurement of circulating substrate concentrations does not provide information about substrate kinetics. It, therefore, remains unclear if a decrease in plasma concentration of albumin, as seen during cr... (Source: Critical Care)
Source: Critical Care - December 17, 2021 Category: Intensive Care Authors: Keisuke Omiya, Hiroaki Sato, Tamaki Sato, Linda Wykes, Mengyin Hong, Roupen Hatzakorzian, Arnold S. Kristof and Thomas Schricker Tags: Research Source Type: research

Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?
(Source: Critical Care)
Source: Critical Care - December 17, 2021 Category: Intensive Care Authors: Lies Langouche, Greet Van den Berghe and Jan Gunst Tags: Commentary Source Type: research

How to monitor thiopental administration in the intensive care unit for refectory status epilepticus or intracranial hypertension?
(Source: Critical Care)
Source: Critical Care - December 17, 2021 Category: Intensive Care Authors: Erika Dabricot, In ès Seqat, Frédéric Dailler, Sylvain Rheims, Sebastien Boulogne and Baptiste Balança Tags: Research Letter Source Type: research

Anisodamine microcirulatory effects in septic shock: be aware of cardiac side effects
(Source: Critical Care)
Source: Critical Care - December 16, 2021 Category: Intensive Care Authors: Patrick M. Honore, Sebastien Redant, Thierry Preseau, Bogdan Vasile Cismas, Keitiane Kaefer, Leonel Barreto Gutierrez, Sami Anane, Rachid Attou, Andrea Gallerani and David De Bels Tags: Letter Source Type: research

17 α-Ethinyl estradiol-3-sulfate increases survival and hemodynamic functioning in a large animal model of combined traumatic brain injury and hemorrhagic shock: a randomized control trial
Traumatic brain injury (TBI) and severe blood loss resulting in hemorrhagic shock (HS) represent leading causes of trauma-induced mortality, especially when co-occurring in pre-hospital settings where standard... (Source: Critical Care)
Source: Critical Care - December 16, 2021 Category: Intensive Care Authors: Andrew R. Mayer, Andrew B. Dodd, Julie G. Rannou-Latella, David D. Stephenson, Rebecca J. Dodd, Josef M. Ling, Carissa J. Mehos, Cidney R. Robertson-Benta, Sharvani Pabbathi Reddy, Rachel E. Kinsler, Meghan S. Vermillion, Andrew P. Gigliotti, Veronik Sica Tags: Research Source Type: research

Orthodeoxia and its implications on awake-proning in COVID-19 pneumonia
(Source: Critical Care)
Source: Critical Care - December 16, 2021 Category: Intensive Care Authors: Lorenzo Giosa, Didier Payen, Mattia Busana, Alessio Mattei, Luca Brazzi and Pietro Caironi Tags: Research Letter Source Type: research

Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness
Critical illness is hallmarked by neuroendocrine alterations throughout ICU stay. We investigated whether the neuroendocrine axes recover after ICU discharge and whether any residual abnormalities associate wi... (Source: Critical Care)
Source: Critical Care - December 16, 2021 Category: Intensive Care Authors: Ilse Vanhorebeek, Inge Derese, Jan Gunst, Pieter J. Wouters, Greet Hermans and Greet Van den Berghe Tags: Research Source Type: research

Positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome: the heterogeneous effects
We hypothesized that as CARDS may present different pathophysiological features than classic ARDS, the application of high levels of end-expiratory pressure is questionable. Our first aim was to investigate th... (Source: Critical Care)
Source: Critical Care - December 16, 2021 Category: Intensive Care Authors: Davide Chiumello, Matteo Bonifazi, Tommaso Pozzi, Paolo Formenti, Giuseppe Francesco Sferrazza Papa, Gabriele Zuanetti and Silvia Coppola Tags: Research Source Type: research