Low levels of small HDL particles predict but do not influence risk of sepsis
Low levels of high-density lipoprotein (HDL) cholesterol have been associated with higher rates and severity of infection. Alterations in inflammatory mediators and infection are associated with alterations in... (Source: Critical Care)
Source: Critical Care - October 9, 2023 Category: Intensive Care Authors: Fergus Hamilton, Kasper M ønsted Pedersen, Peter Ghazal, Børge Grønne Nordestgaard and George Davey Smith Tags: Research Source Type: research

Improvement of composite kidney outcomes by AKI care bundles: a systematic review and meta-analysis
The objective of this study was to evaluate whethe... (Source: Critical Care)
Source: Critical Care - October 9, 2023 Category: Intensive Care Authors: Chun Yin See, Heng-Chih Pan, Jui-Yi Chen, Chun-Yi Wu, Hung-Wei Liao, Yen-Ta Huang, Jung-Hua Liu, Vin-Cent Wu and Marlies Ostermann Tags: Research Source Type: research

Reflections of an intensivist in 2050: three decades of clinical practice, research, and human connection
(Source: Critical Care)
Source: Critical Care - October 9, 2023 Category: Intensive Care Authors: Maurizio Cecconi Tags: Editorial Source Type: research

Identification of post-cardiac arrest blood pressure thresholds associated with outcomes in children: an ICU-Resuscitation study
Though early hypotension after pediatric in-hospital cardiac arrest (IHCA) is associated with inferior outcomes, ideal post-arrest blood pressure (BP) targets have not been established. We aimed to leverage pr... (Source: Critical Care)
Source: Critical Care - October 7, 2023 Category: Intensive Care Authors: Monique M. Gardner, David A. Hehir, Ron W. Reeder, Tageldin Ahmed, Michael J. Bell, Robert A. Berg, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A. Carcillo, Todd C. Carpenter, J. Michael Dean, J. Wesley Diddle, Myke Federman, Richard Fernandez Tags: Research Source Type: research

The spectrum of sepsis-associated encephalopathy: a clinical perspective
Sepsis-associated encephalopathy is a severe neurologic syndrome characterized by a diffuse dysfunction of the brain caused by sepsis. This review provides a concise overview of diagnostic tools and management... (Source: Critical Care)
Source: Critical Care - October 5, 2023 Category: Intensive Care Authors: Romain Sonneville, Sarah Benghanem, Lina Jeantin, Etienne de Montmollin, Marc Doman, Augustin Gaudemer, Michael Thy and Jean-Fran çois Timsit Tags: Review Source Type: research

Restrictive versus high-dose oxygenation strategy in post-arrest management following adult non-traumatic cardiac arrest: a meta-analysis
Neurological damage is the main cause of death or withdrawal of care in comatose survivors of cardiac arrest (CA). Hypoxemia and hyperoxemia following CA were described as potentially harmful, but reports were... (Source: Critical Care)
Source: Critical Care - October 5, 2023 Category: Intensive Care Authors: S. Macherey-Meyer, S. Heyne, M. M. Meertens, S. Braumann, C. Hueser, V. Mauri, S. Baldus, S. Lee and C. Adler Tags: Research Source Type: research

Lung abscess following ventilator-associated pneumonia during COVID-19: a retrospective multicenter cohort study
Patients undergoing mechanical ventilation (MV) for COVID-19 exhibit an increased risk of ventilator-associated pneumonia (VAP). The occurrence of lung abscesses following VAP in these patients has been poorly... (Source: Critical Care)
Source: Critical Care - October 4, 2023 Category: Intensive Care Authors: S. Hraiech, K. Ladjal, C. Guervilly, H. Hyvernat, L. Papazian, J. M. Forel, A. Lopez, N. Peres, J. Dellamonica, M. Leone and I. Gragueb-Chatti Tags: Research Source Type: research

Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial
Restoring plasma arginine levels through enteral administration of L-citrulline in critically ill patients may improve outcomes. We aimed to evaluate whether enteral L-citrulline administration reduced organ d... (Source: Critical Care)
Source: Critical Care - October 3, 2023 Category: Intensive Care Authors: Jean-Marc Tadi é, Clara Locher, Adel Maamar, Jean Reignier, Pierre Asfar, Morgane Commereuc, Mathieu Lesouhaitier, Murielle Gregoire, Estelle Le Pabic, Claude Bendavid, Caroline Moreau, Jean-Luc Diehl, Alain Gey, Eric Tartour, Yves Le Tulzo, Ronan Thibau Tags: Research Source Type: research

Critical appraisal beyond clinical guidelines for intraabdominal candidiasis
Regardless of the available antifungals, intraabdominal candidiasis (IAC) mortality continues to be high and represents a challenge for clinicians. (Source: Critical Care)
Source: Critical Care - October 3, 2023 Category: Intensive Care Authors: Emilio Maseda, Ignacio Mart ín-Loeches, Rafael Zaragoza, Javier Pemán, Jesús Fortún, Santiago Grau, Gerardo Aguilar, Marina Varela, Marcio Borges, María-José Giménez and Alejandro Rodríguez Tags: Perspective Source Type: research

Pharyngeal electrical stimulation for postextubation dysphagia in acute stroke: a randomized controlled pilot trial
(Source: Critical Care)
Source: Critical Care - October 3, 2023 Category: Intensive Care Authors: Sonja Suntrup-Krueger, Bendix Labeit, Thomas Marian, Jens Schr öder, Inga Claus, Sigrid Ahring, Tobias Warnecke, Rainer Dziewas and Paul Muhle Tags: Correspondence Source Type: research

Shedding light on carboxyhaemoglobin in extracorporeal membrane oxygenation
(Source: Critical Care)
Source: Critical Care - October 3, 2023 Category: Intensive Care Authors: Kenneth R. Hoffman, Arne Diehl, Eldho Paul, Warwick Butt and Aidan J. C. Burrell Tags: Correspondence Source Type: research

Training in critical care cardiology: making the case for a standardized core curriculum
(Source: Critical Care)
Source: Critical Care - October 2, 2023 Category: Intensive Care Authors: Leonhard Binzenh öfer, Holger Thiele and Enzo Lüsebrink Tags: Editorial Source Type: research

Improvement of central vein ultrasound-guided puncture success using a homemade needle guide —a simulation study
Out-of-plane (OOP) approach is frequently used for ultrasound-guided insertion of central venous catheter (CVC) owing to its simplicity but does not avoid mechanical complication. In-plane (IP) approach might ... (Source: Critical Care)
Source: Critical Care - September 30, 2023 Category: Intensive Care Authors: Antoine Villa, Vladimir Hermand, Vincent Bonny, Gabriel Preda, Tomas Urbina, Maxime Gasperment, Paul Gabarre, Louai Missri, Jean-Luc Baudel, Daniel Zafimahazo, J érémie Joffre, Hafid Ait-Oufella and Eric Maury Tags: Brief Report Source Type: research

Can normal breath sounds in mechanically ventilated patients be termed vesicular?
(Source: Critical Care)
Source: Critical Care - September 30, 2023 Category: Intensive Care Authors: Sai Saran, Saumitra Misra, Avinash Agrawal and Suhail Sarwar Siddiqui Tags: Correspondence Source Type: research

Time definition of reintubation most relevant to patient outcomes in critically ill patients: a multicenter cohort study
Reintubation is a common complication in critically ill patients requiring mechanical ventilation. Although reintubation has been demonstrated to be associated with patient outcomes, its time definition varies... (Source: Critical Care)
Source: Critical Care - September 30, 2023 Category: Intensive Care Authors: Aiko Tanaka, Yoshimitsu Shimomura, Akinori Uchiyama, Natsuko Tokuhira, Tetsuhisa Kitamura, Hirofumi Iwata, Haruka Hashimoto, Suguru Ishigaki, Yusuke Enokidani, Tomonori Yamashita, Yukiko Koyama, Naoya Iguchi, Takeshi Yoshida and Yuji Fujino Tags: Research Source Type: research