Central administered xenin induced Fos expression in nesfatin-1 neurons in rats
Brain Res Bull. 2023 Oct 14:110788. doi: 10.1016/j.brainresbull.2023.110788. Online ahead of print.ABSTRACTXenin is a 25-amino acid peptide identified in human gastric mucosa, which is widely expressed in peripheral and central tissues. It is known that the central or peripheral administration of xenin decreases food intake in rodents. Nesfatin-1/NUCB2 (nesfatin-1) has been identified as an anorexic neuropeptide, it is often found co-localized with many peptides in the central nervous system. After the intracerebroventricular administration of xenin on nesfain-1-like immunoreactivity (LI) neurons, we examined its effects o...
Source: Brain Research Bulletin - October 16, 2023 Category: Neurology Authors: Shota Saito Hirofumi Hashimoto Hidefumi Wakashin Misaki Ishibane Sangjon Pae Shinpei Saito Yoshie Reien Yuri Hirayama Yoshiteru Seo Takashi Mizushima Naohiko Anzai Source Type: research
Possible mechanisms involved in the neuroprotective effects of chrysin against mild traumatic brain injury-induced spatial cognitive decline: An in vivo study in a rat model
Brain Res Bull. 2023 Oct 10:110779. doi: 10.1016/j.brainresbull.2023.110779. Online ahead of print.ABSTRACTTraumatic brain injury (TBI) is recognized as an important risk factor for cognitive deficits. The present study was designed to determine the potential neuroprotective effects of chrysin, a natural flavonoid compound, against TBI-induced spatial cognitive decline and the possible mechanisms involved. Oral administration of chrysin (25, 50, or 100mg/kg/day) was initiated in rats immediately following the induction of the diffuse TBI model using the weight-dropping Marmarou model. Spatial cognitive ability, hippocampal...
Source: Brain Research Bulletin - October 12, 2023 Category: Neurology Authors: Masome Rashno Alireza Sarkaki Yaghoob Farbood Mohammad Rashno Layasadat Khorsandi Mohammad Kazem Gharib Naseri Mahin Dianat Source Type: research
Possible mechanisms involved in the neuroprotective effects of chrysin against mild traumatic brain injury-induced spatial cognitive decline: An in vivo study in a rat model
Brain Res Bull. 2023 Oct 10:110779. doi: 10.1016/j.brainresbull.2023.110779. Online ahead of print.ABSTRACTTraumatic brain injury (TBI) is recognized as an important risk factor for cognitive deficits. The present study was designed to determine the potential neuroprotective effects of chrysin, a natural flavonoid compound, against TBI-induced spatial cognitive decline and the possible mechanisms involved. Oral administration of chrysin (25, 50, or 100mg/kg/day) was initiated in rats immediately following the induction of the diffuse TBI model using the weight-dropping Marmarou model. Spatial cognitive ability, hippocampal...
Source: Brain Research Bulletin - October 12, 2023 Category: Neurology Authors: Masome Rashno Alireza Sarkaki Yaghoob Farbood Mohammad Rashno Layasadat Khorsandi Mohammad Kazem Gharib Naseri Mahin Dianat Source Type: research
Possible mechanisms involved in the neuroprotective effects of chrysin against mild traumatic brain injury-induced spatial cognitive decline: An in vivo study in a rat model
Brain Res Bull. 2023 Oct 10:110779. doi: 10.1016/j.brainresbull.2023.110779. Online ahead of print.ABSTRACTTraumatic brain injury (TBI) is recognized as an important risk factor for cognitive deficits. The present study was designed to determine the potential neuroprotective effects of chrysin, a natural flavonoid compound, against TBI-induced spatial cognitive decline and the possible mechanisms involved. Oral administration of chrysin (25, 50, or 100mg/kg/day) was initiated in rats immediately following the induction of the diffuse TBI model using the weight-dropping Marmarou model. Spatial cognitive ability, hippocampal...
Source: Brain Research Bulletin - October 12, 2023 Category: Neurology Authors: Masome Rashno Alireza Sarkaki Yaghoob Farbood Mohammad Rashno Layasadat Khorsandi Mohammad Kazem Gharib Naseri Mahin Dianat Source Type: research
Possible mechanisms involved in the neuroprotective effects of chrysin against mild traumatic brain injury-induced spatial cognitive decline: An in vivo study in a rat model
Brain Res Bull. 2023 Oct 10:110779. doi: 10.1016/j.brainresbull.2023.110779. Online ahead of print.ABSTRACTTraumatic brain injury (TBI) is recognized as an important risk factor for cognitive deficits. The present study was designed to determine the potential neuroprotective effects of chrysin, a natural flavonoid compound, against TBI-induced spatial cognitive decline and the possible mechanisms involved. Oral administration of chrysin (25, 50, or 100mg/kg/day) was initiated in rats immediately following the induction of the diffuse TBI model using the weight-dropping Marmarou model. Spatial cognitive ability, hippocampal...
Source: Brain Research Bulletin - October 12, 2023 Category: Neurology Authors: Masome Rashno Alireza Sarkaki Yaghoob Farbood Mohammad Rashno Layasadat Khorsandi Mohammad Kazem Gharib Naseri Mahin Dianat Source Type: research
