Discriminative analysis of schizophrenia patients using an integrated model combining 3D CNN with 2D CNN: A multimodal MR image and connectomics analysis
CONCLUSIONS: Our findings indicated that an integrated model combining 3D CNN with 2D CNN is a promising method to improve the classification performance of SZ patients and has potential for the clinical diagnosis of psychiatric diseases.PMID:38104672 | DOI:10.1016/j.brainresbull.2023.110846 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 17, 2023 Category: Neurology Authors: Haiman Guo Shuyi Jian Yubin Zhou Xiaoyi Chen Jinbiao Chen Jing Zhou Yuanyuan Huang Guolin Ma Xiaobo Li Yuping Ning Fengchun Wu Kai Wu Source Type: research

Multi feature fusion network for schizophrenia classification and abnormal brain network recognition
In conclusion, this method can identify schizophrenia effectively and visualize the abnormal brain network, and it has important clinical application value.PMID:38104673 | DOI:10.1016/j.brainresbull.2023.110848 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 17, 2023 Category: Neurology Authors: Chang Wang Chen Wang Yaning Ren Rui Zhang Lunpu Ai Yang Wu Xiangying Ran Mengke Wang Heshun Hu Jiefen Shen Zongya Zhao Yongfeng Yang Wenjie Ren Yi Yu Source Type: research

Discriminative analysis of schizophrenia patients using an integrated model combining 3D CNN with 2D CNN: A multimodal MR image and connectomics analysis
CONCLUSIONS: Our findings indicated that an integrated model combining 3D CNN with 2D CNN is a promising method to improve the classification performance of SZ patients and has potential for the clinical diagnosis of psychiatric diseases.PMID:38104672 | DOI:10.1016/j.brainresbull.2023.110846 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 17, 2023 Category: Neurology Authors: Haiman Guo Shuyi Jian Yubin Zhou Xiaoyi Chen Jinbiao Chen Jing Zhou Yuanyuan Huang Guolin Ma Xiaobo Li Yuping Ning Fengchun Wu Kai Wu Source Type: research

Multi feature fusion network for schizophrenia classification and abnormal brain network recognition
In conclusion, this method can identify schizophrenia effectively and visualize the abnormal brain network, and it has important clinical application value.PMID:38104673 | DOI:10.1016/j.brainresbull.2023.110848 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 17, 2023 Category: Neurology Authors: Chang Wang Chen Wang Yaning Ren Rui Zhang Lunpu Ai Yang Wu Xiangying Ran Mengke Wang Heshun Hu Jiefen Shen Zongya Zhao Yongfeng Yang Wenjie Ren Yi Yu Source Type: research

Association Between Altered White Matter Networks and Post Operative Ventricle Volume in Shunt-Treated Pediatric Hydrocephalus
CONCLUSIONS: This cross-sectional study in pediatric patients with hydrocephalus and healthy controls demonstrated using whole-brain probabilistic tractography that there are various networks with dysregulated white matter integrity in hydrocephalus patients relative to controls. These dysregulated networks have tracts connecting structures throughout the brain, and the regions were predominately located centrally and posteriorly. Post-operative ventricle volume did not predict the white matter integrity of many tracts. Future studies with larger sample sizes are needed to further understand these results.PMID:38103800 | D...
Source: Brain Research Bulletin - December 16, 2023 Category: Neurology Authors: Renee-Marie Ragguett Roy Eagleson Sandrine de Ribaupierre Source Type: research

Association Between Altered White Matter Networks and Post Operative Ventricle Volume in Shunt-Treated Pediatric Hydrocephalus
CONCLUSIONS: This cross-sectional study in pediatric patients with hydrocephalus and healthy controls demonstrated using whole-brain probabilistic tractography that there are various networks with dysregulated white matter integrity in hydrocephalus patients relative to controls. These dysregulated networks have tracts connecting structures throughout the brain, and the regions were predominately located centrally and posteriorly. Post-operative ventricle volume did not predict the white matter integrity of many tracts. Future studies with larger sample sizes are needed to further understand these results.PMID:38103800 | D...
Source: Brain Research Bulletin - December 16, 2023 Category: Neurology Authors: Renee-Marie Ragguett Roy Eagleson Sandrine de Ribaupierre Source Type: research

Longitudinal Trajectory of Amplitude of Low-Frequency Fluctuation Changes in Breast Cancer Patients During Neoadjuvant Chemotherapy-A Preliminary Prospective Study
Brain Res Bull. 2023 Dec 13:110845. doi: 10.1016/j.brainresbull.2023.110845. Online ahead of print.ABSTRACTThere is growing evidence that the amplitude of low-frequency fluctuation (ALFF) changes in breast cancer patients after chemotherapy. However, longitudinal changes in ALFF during chemotherapy are unclear. To assess the trajectory of ALFF changes during chemotherapy, 36 breast cancer patients underwent both resting-state functional magnetic resonance imaging and neuropsychological testing at three time points, including before neoadjuvant chemotherapy (NAC) (time point 0, TP0), after one cycle of NAC (before the secon...
Source: Brain Research Bulletin - December 15, 2023 Category: Neurology Authors: Yixin Hu Hong Yu Yong Lai Jiang Liu Yong Tan Weiwei Lei Jing Zhang Xiaoyu Zhou Ying Cao Yu Tang Daihong Liu Jiuquan Zhang Source Type: research

Analgesic effect of linalool odor on oral ulcerative mucositis-induced pain in rats
In this study, we examined the mechanism underlying the analgesic effect of linalool odor on oral pain caused by OUM using nocifensive behavioral and immunohistochemical analyses in rats. OUM was developed by treating the labial fornix region of the inferior incisors with acetic acid. Linalool at 1% was exposed for 5 min at 30 min before nocifensive behavioral measurements. OUM induced spontaneous pain and mechanical allodynia, which were suppressed by the linalool odor. Mechanical allodynia in the hind paw following the injection of complete Freund's adjuvant was also suppressed by linalool odor. Application of lidocaine ...
Source: Brain Research Bulletin - December 14, 2023 Category: Neurology Authors: Masato Iida Suzuro Hitomi Yoshinori Hayashi Ikuko Shibuta Yoshiyuki Tsuboi Koichiro Ueda Koichi Iwata Masamichi Shinoda Source Type: research

Analgesic effect of linalool odor on oral ulcerative mucositis-induced pain in rats
In this study, we examined the mechanism underlying the analgesic effect of linalool odor on oral pain caused by OUM using nocifensive behavioral and immunohistochemical analyses in rats. OUM was developed by treating the labial fornix region of the inferior incisors with acetic acid. Linalool at 1% was exposed for 5min at 30min before nocifensive behavioral measurements. OUM induced spontaneous pain and mechanical allodynia, which were suppressed by the linalool odor. Mechanical allodynia in the hind paw following the injection of complete Freund's adjuvant was also suppressed by linalool odor. Application of lidocaine to...
Source: Brain Research Bulletin - December 14, 2023 Category: Neurology Authors: Masato Iida Suzuro Hitomi Yoshinori Hayashi Ikuko Shibuta Yoshiyuki Tsuboi Koichiro Ueda Koichi Iwata Masamichi Shinoda Source Type: research

Diosmin ameliorates LPS-induced depression-like behaviors in mice: inhibition of inflammation and oxidative stress in the prefrontal cortex
Brain Res Bull. 2023 Dec 11:110843. doi: 10.1016/j.brainresbull.2023.110843. Online ahead of print.ABSTRACTDiosmin is a flavone glycoside with a confirmed therapeutic effectiveness on the chronic venous disorders. In this paper, the classical mouse depression model induced by LPS was established to explore the effect of Diosmin on depression. Firstly, we found that Diosmin could inhibit the inflammation and neuronal damage in the prefrontal cortex (PFC) of mice, and thus alleviating the LPS-induced depressive-like behaviors. Specifically, Diosmin treatment significantly suppressed the secretion of pro-inflammatory cytokine...
Source: Brain Research Bulletin - December 13, 2023 Category: Neurology Authors: Jingwei Zhao Mingming Zhang Huamin Zhang Ying Wang Bingyu Chen Jing Shao Source Type: research

Diosmin ameliorates LPS-induced depression-like behaviors in mice: inhibition of inflammation and oxidative stress in the prefrontal cortex
Brain Res Bull. 2023 Dec 11:110843. doi: 10.1016/j.brainresbull.2023.110843. Online ahead of print.ABSTRACTDiosmin is a flavone glycoside with a confirmed therapeutic effectiveness on the chronic venous disorders. In this paper, the classical mouse depression model induced by LPS was established to explore the effect of Diosmin on depression. Firstly, we found that Diosmin could inhibit the inflammation and neuronal damage in the prefrontal cortex (PFC) of mice, and thus alleviating the LPS-induced depressive-like behaviors. Specifically, Diosmin treatment significantly suppressed the secretion of pro-inflammatory cytokine...
Source: Brain Research Bulletin - December 13, 2023 Category: Neurology Authors: Jingwei Zhao Mingming Zhang Huamin Zhang Ying Wang Bingyu Chen Jing Shao Source Type: research

Altered intrinsic brain activity in patients with neuropathic pain after brachial plexus avulsion
CONCLUSIONS: The NP after BPA caused spontaneous activity changes in brain regions associated with linguistic, visual, somatosensory, and motor coordination and processing function. The majority of these abnormal areas were situated in the left cerebral hemisphere, while the effect of cingulate gyri and cerebellum seemed to be bilateral.PMID:38056510 | DOI:10.1016/j.brainresbull.2023.110831 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 6, 2023 Category: Neurology Authors: Jin Zhu Rui Gu Liang Shi Yibing Su Source Type: research

Altered intrinsic brain activity in patients with neuropathic pain after brachial plexus avulsion
CONCLUSIONS: The NP after BPA caused spontaneous activity changes in brain regions associated with linguistic, visual, somatosensory, and motor coordination and processing function. The majority of these abnormal areas were situated in the left cerebral hemisphere, while the effect of cingulate gyri and cerebellum seemed to be bilateral.PMID:38056510 | DOI:10.1016/j.brainresbull.2023.110831 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 6, 2023 Category: Neurology Authors: Jin Zhu Rui Gu Liang Shi Yibing Su Source Type: research

Altered intrinsic brain activity in patients with neuropathic pain after brachial plexus avulsion
CONCLUSIONS: The NP after BPA caused spontaneous activity changes in brain regions associated with linguistic, visual, somatosensory, and motor coordination and processing function. The majority of these abnormal areas were situated in the left cerebral hemisphere, while the effect of cingulate gyri and cerebellum seemed to be bilateral.PMID:38056510 | DOI:10.1016/j.brainresbull.2023.110831 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 6, 2023 Category: Neurology Authors: Jin Zhu Rui Gu Liang Shi Yibing Su Source Type: research

Altered intrinsic brain activity in patients with neuropathic pain after Brachial plexus avulsion
CONCLUSIONS: The NP after BPA caused spontaneous activity changes in brain regions associated with linguistic, visual, somatosensory, and motor coordination and processing function. The majority of these abnormal areas were situated in the left cerebral hemisphere, while the effect of cingulate gyri and cerebellum seemed to be bilateral.PMID:38056510 | DOI:10.1016/j.brainresbull.2023.110831 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - December 6, 2023 Category: Neurology Authors: Jin Zhu Rui Gu Liang Shi Yibing Su Source Type: research