Consistent abnormal activity in the putamen by dopamine modulation in Parkinson's disease: A resting-state neuroimaging meta-analysis
CONCLUSIONS: The convergence of local brain regions and co-activation neural networks are involved the putamen, suggesting its potential as a specific imaging biomarker to monitor treatment efficacy.SYSTEMATIC REVIEW REGISTRATION: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD CRD42022304150].PMID:38508469 | DOI:10.1016/j.brainresbull.2024.110933 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Danyan Rong Chuan-Peng Hu Jiaying Yang Zhiying Guo Weiguo Liu Miao Yu Source Type: research
Associations between somatomotor-putamen resting state connectivity and obsessive-compulsive symptoms vary as a function of stress during early adolescence: Data from the ABCD Study
This study examined somatomotor-putamen resting state connectivity, stress, and their interaction on OCS in adolescents from 9-12 years of age. Participants (n = 6,386) were drawn from the ABCD Study 4.0 release. Multilevel modeling was used to account for nesting in the data and to assess changes in OCS in this age range. Stress moderated the association between somatomotor-putamen connectivity and OCS (β = 0.35, S.E. = 0.13, p = 0.006). Participants who reported more stress than their average and had greater somatomotor-left putamen connectivity reported more OCS, whereas participants who reported less stress than their...
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Daniel J Petrie Kathleen D Meeks Zachary F Fisher Charles F Geier Source Type: research
Consistent abnormal activity in the putamen by dopamine modulation in Parkinson's disease: A resting-state neuroimaging meta-analysis
CONCLUSIONS: The convergence of local brain regions and co-activation neural networks are involved the putamen, suggesting its potential as a specific imaging biomarker to monitor treatment efficacy.SYSTEMATIC REVIEW REGISTRATION: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD CRD42022304150].PMID:38508469 | DOI:10.1016/j.brainresbull.2024.110933 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Danyan Rong Chuan-Peng Hu Jiaying Yang Zhiying Guo Weiguo Liu Miao Yu Source Type: research
Associations between somatomotor-putamen resting state connectivity and obsessive-compulsive symptoms vary as a function of stress during early adolescence: Data from the ABCD Study
This study examined somatomotor-putamen resting state connectivity, stress, and their interaction on OCS in adolescents from 9-12 years of age. Participants (n = 6,386) were drawn from the ABCD Study 4.0 release. Multilevel modeling was used to account for nesting in the data and to assess changes in OCS in this age range. Stress moderated the association between somatomotor-putamen connectivity and OCS (β = 0.35, S.E. = 0.13, p = 0.006). Participants who reported more stress than their average and had greater somatomotor-left putamen connectivity reported more OCS, whereas participants who reported less stress than their...
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Daniel J Petrie Kathleen D Meeks Zachary F Fisher Charles F Geier Source Type: research
Consistent abnormal activity in the putamen by dopamine modulation in Parkinson's disease: A resting-state neuroimaging meta-analysis
CONCLUSIONS: The convergence of local brain regions and co-activation neural networks are involved the putamen, suggesting its potential as a specific imaging biomarker to monitor treatment efficacy.SYSTEMATIC REVIEW REGISTRATION: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD CRD42022304150].PMID:38508469 | DOI:10.1016/j.brainresbull.2024.110933 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Danyan Rong Chuan-Peng Hu Jiaying Yang Zhiying Guo Weiguo Liu Miao Yu Source Type: research
Associations between somatomotor-putamen resting state connectivity and obsessive-compulsive symptoms vary as a function of stress during early adolescence: Data from the ABCD Study
This study examined somatomotor-putamen resting state connectivity, stress, and their interaction on OCS in adolescents from 9-12 years of age. Participants (n = 6,386) were drawn from the ABCD Study 4.0 release. Multilevel modeling was used to account for nesting in the data and to assess changes in OCS in this age range. Stress moderated the association between somatomotor-putamen connectivity and OCS (β = 0.35, S.E. = 0.13, p = 0.006). Participants who reported more stress than their average and had greater somatomotor-left putamen connectivity reported more OCS, whereas participants who reported less stress than their...
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Daniel J Petrie Kathleen D Meeks Zachary F Fisher Charles F Geier Source Type: research
Consistent abnormal activity in the putamen by dopamine modulation in Parkinson's disease: A resting-state neuroimaging meta-analysis
CONCLUSIONS: The convergence of local brain regions and co-activation neural networks are involved the putamen, suggesting its potential as a specific imaging biomarker to monitor treatment efficacy.SYSTEMATIC REVIEW REGISTRATION: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD CRD42022304150].PMID:38508469 | DOI:10.1016/j.brainresbull.2024.110933 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Danyan Rong Chuan-Peng Hu Jiaying Yang Zhiying Guo Weiguo Liu Miao Yu Source Type: research
Associations between somatomotor-putamen resting state connectivity and obsessive-compulsive symptoms vary as a function of stress during early adolescence: Data from the ABCD Study
This study examined somatomotor-putamen resting state connectivity, stress, and their interaction on OCS in adolescents from 9-12 years of age. Participants (n = 6,386) were drawn from the ABCD Study 4.0 release. Multilevel modeling was used to account for nesting in the data and to assess changes in OCS in this age range. Stress moderated the association between somatomotor-putamen connectivity and OCS (β = 0.35, S.E. = 0.13, p = 0.006). Participants who reported more stress than their average and had greater somatomotor-left putamen connectivity reported more OCS, whereas participants who reported less stress than their...
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Daniel J Petrie Kathleen D Meeks Zachary F Fisher Charles F Geier Source Type: research
Consistent abnormal activity in the putamen by dopamine modulation in Parkinson's disease: A resting-state neuroimaging meta-analysis
CONCLUSIONS: The convergence of local brain regions and co-activation neural networks are involved the putamen, suggesting its potential as a specific imaging biomarker to monitor treatment efficacy.SYSTEMATIC REVIEW REGISTRATION: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD CRD42022304150].PMID:38508469 | DOI:10.1016/j.brainresbull.2024.110933 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Danyan Rong Chuan-Peng Hu Jiaying Yang Zhiying Guo Weiguo Liu Miao Yu Source Type: research
Associations between somatomotor-putamen resting state connectivity and obsessive-compulsive symptoms vary as a function of stress during early adolescence: Data from the ABCD Study
This study examined somatomotor-putamen resting state connectivity, stress, and their interaction on OCS in adolescents from 9-12 years of age. Participants (n = 6,386) were drawn from the ABCD Study 4.0 release. Multilevel modeling was used to account for nesting in the data and to assess changes in OCS in this age range. Stress moderated the association between somatomotor-putamen connectivity and OCS (β = 0.35, S.E. = 0.13, p = 0.006). Participants who reported more stress than their average and had greater somatomotor-left putamen connectivity reported more OCS, whereas participants who reported less stress than their...
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Daniel J Petrie Kathleen D Meeks Zachary F Fisher Charles F Geier Source Type: research
Consistent abnormal activity in the putamen by dopamine modulation in Parkinson's disease: A resting-state neuroimaging meta-analysis
CONCLUSIONS: The convergence of local brain regions and co-activation neural networks are involved the putamen, suggesting its potential as a specific imaging biomarker to monitor treatment efficacy.SYSTEMATIC REVIEW REGISTRATION: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD CRD42022304150].PMID:38508469 | DOI:10.1016/j.brainresbull.2024.110933 (Source: Brain Research Bulletin)
Source: Brain Research Bulletin - March 20, 2024 Category: Neurology Authors: Danyan Rong Chuan-Peng Hu Jiaying Yang Zhiying Guo Weiguo Liu Miao Yu Source Type: research
Sleep deprivation changes frequency-specific functional organization of the resting human brain
In this study, thirty-seven healthy male subjects underwent resting-state fMRI during rested wakefulness (RW) and after 36hours of SD, and we examined frequency-specific spectral connection changes (0.01-0.08Hz, interval = 0.01Hz) caused by SD. First, we conducted a multivariate pattern analysis combining linear SVM classifiers with a robust feature selection algorithm, and the results revealed that accuracies of 74.29%-84.29% could be achieved in the classification between RW and SD states in leave-one-out cross-validation at different frequency bands, moreover, the spectral connection at the lowest and highest frequency ...
Source: Brain Research Bulletin - March 17, 2024 Category: Neurology Authors: Zhiguo Luo Erwei Yin Ye Yan Shaokai Zhao Liang Xie Hui Shen Ling-Li Zeng Lubin Wang Dewen Hu Source Type: research
Inhibition of lysyl oxidase by pharmacological intervention and genetic manipulation alleviates epilepsy-associated cognitive disorder
Brain Res Bull. 2024 Mar 15;210:110928. doi: 10.1016/j.brainresbull.2024.110928. Online ahead of print.ABSTRACTEpilepsy-associated cognitive disorder (ECD), a prevalent comorbidity in epilepsy patients, has so far uncharacterized etiological origins. Our prior work revealed that lysyl oxidase (Lox) acted as a novel contributor of ferroptosis, a recently discovered cell death mode in the regulation of brain function. However, the role of Lox-mediated ferroptosis in ECD remains unknown. ECD mouse model was established 2 months later following a single injection of kainic acid (KA) for. After chronic treatment with KA, mice w...
Source: Brain Research Bulletin - March 17, 2024 Category: Neurology Authors: Kang-Ni Chen Qi-Lin Peng Dan-Feng Cao Zhao-Jun Wang Kai Zhang Xin-Yu Zhou Dong-Yu Min Bo-Ting Zhou Xiao-Yuan Mao Source Type: research
Sleep deprivation changes frequency-specific functional organization of the resting human brain
In this study, thirty-seven healthy male subjects underwent resting-state fMRI during rested wakefulness (RW) and after 36hours of SD, and we examined frequency-specific spectral connection changes (0.01-0.08Hz, interval = 0.01Hz) caused by SD. First, we conducted a multivariate pattern analysis combining linear SVM classifiers with a robust feature selection algorithm, and the results revealed that accuracies of 74.29%-84.29% could be achieved in the classification between RW and SD states in leave-one-out cross-validation at different frequency bands, moreover, the spectral connection at the lowest and highest frequency ...
Source: Brain Research Bulletin - March 17, 2024 Category: Neurology Authors: Zhiguo Luo Erwei Yin Ye Yan Shaokai Zhao Liang Xie Hui Shen Ling-Li Zeng Lubin Wang Dewen Hu Source Type: research
Inhibition of lysyl oxidase by pharmacological intervention and genetic manipulation alleviates epilepsy-associated cognitive disorder
Brain Res Bull. 2024 Mar 15:110928. doi: 10.1016/j.brainresbull.2024.110928. Online ahead of print.ABSTRACTEpilepsy-associated cognitive disorder (ECD), a prevalent comorbidity in epilepsy patients, has so far uncharacterized etiological origins. Our prior work revealed that lysyl oxidase (Lox) acted as a novel contributor of ferroptosis, a recently discovered cell death mode in the regulation of brain function. However, the role of Lox-mediated ferroptosis in ECD remains unknown. ECD mouse model was established 2 months later following a single injection of kainic acid (KA) for. After chronic treatment with KA, mice were ...
Source: Brain Research Bulletin - March 17, 2024 Category: Neurology Authors: Kang-Ni Chen Qi-Lin Peng Dan-Feng Cao Zhao-Jun Wang Kai Zhang Xin-Yu Zhou Dong-Yu Min Bo-Ting Zhou Xiao-Yuan Mao Source Type: research
