Attenuation of LPS-induced acute lung injury by continentalic acid in rodents through inhibition of inflammatory mediators correlates with increased Nrf2 protein expression
Acute lung injury (ALI) together with acute respiratory distress syndrome (ARDS) are associated with high rate of mortality and morbidity in patients. In the current study, the anti-inflammatory effects of con... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - November 25, 2020 Category: Drugs & Pharmacology Authors: Hassan Ali, Ashrafullah Khan, Jawad Ali, Hadayat Ullah, Adnan Khan, Hussain Ali, Nadeem Irshad and Salman Khan Tags: Research article Source Type: research
Pharmacodynamic and pharmacokinetic behavior of landiolol during dobutamine challenge in healthy adults
To study the pharmacokinetic and -dynamic behavior of landiolol in the presence of dobutamine in healthy subjects of European ancestry. (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - November 25, 2020 Category: Drugs & Pharmacology Authors: G ünther Krumpl, Ivan Ulč, Michaela Trebs, Pavla Kadlecová and Juri Hodisch Tags: Research article Source Type: research
Two novel anticancer compounds with minimum cardiotoxic property
Although two novel synthesized compounds with tri-aryl structures; 3-(4-chlorophenyl)-5-(4-fluorophenyl)-4-phenyl-4,5-dihydro-1,2,4-oxadiazole (A) and 3,5-bis-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1,2,4-oxadiazol... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - November 19, 2020 Category: Drugs & Pharmacology Authors: Tayebeh Afsharirad, Raheleh Tahmasvand, Mohsen Amini, Bahram Daraei and Mona Salimi Tags: Research article Source Type: research
Bioequivalence of levamlodipine besylate tablets in healthy Chinese subjects: a single-dose and two-period crossover randomized study
Levamlodipine, a calcium channel blocker, has been show act as a cardiovascular drug. To compare the pharmacokinetic parameters between levamlodipine (test formulation) at a single dose of 5 mg and amlodipine ... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - November 19, 2020 Category: Drugs & Pharmacology Authors: Xin Li, Chenjing Wang, Ting Li, Yanping Liu, Shuqin Liu, Ye Tao, Yaping Ma, Xiaomeng Gao and Yu Cao Tags: Research article Source Type: research
Bioprospecting the antimicrobial, antibiofilm and antiproliferative activity of Symplocos racemosa Roxb. Bark phytoconstituents along with their biosafety evaluation and detection of antimicrobial components by GC-MS
Plants provide a ray of hope to combat the ever increasing antibiotic resistance and Symplocos racemosa is a valuable medicinal plant. The study focused on highlighting the importance of this plant ’s phytoconstit... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - November 17, 2020 Category: Drugs & Pharmacology Authors: Henna Sood, Yashwant Kumar, Vipan Kumar Gupta and Daljit Singh Arora Tags: Research article Source Type: research
