Novel lipid-coated mesoporous silica nanoparticles loaded with thymoquinone formulation to increase its bioavailability in the brain and organs of Wistar rats
The Blood-Brain Barrier (BBB) is a filter for most medications and blocks their passage into the brain. More effective drug delivery strategies are urgently needed to transport medications into the brain. This... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 26, 2022 Category: Drugs & Pharmacology Authors: Heba M. Fahmy, Mostafa M. Ahmed, Ayman S. Mohamed, Engy Shams-Eldin, Taiseer M. Abd El-Daim, Amena S. El-Feky, Amira B. Mustafa, Mai W. Abd Alrahman, Faten F. Mohammed and Mohamed M. Fathy Tags: Research Source Type: research
Demographic, clinical, and laboratory findings of mushroom-poisoned patients in Kermanshah province, west of Iran
Mushroom poisoning can cause gastrointestinal, renal, and hepatic symptoms and even death. This descriptive study examined the demographic, clinical, and laboratory findings of patients with fungal poisoning, ... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 26, 2022 Category: Drugs & Pharmacology Authors: Maryam Janatolmakan, Mohammad Rouhi Ganji, Touraj Ahmadi-Jouybari, Shahab Rezaeian, Mahnaz Ghowsi and Alireza Khatony Tags: Research Source Type: research
The effectiveness of pregabalin with or without agomelatine in the treatment of chronic low back pain: a double-blind, placebo-controlled, randomized clinical trial
This study aimed t... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Seyed Mani Mahdavi, Behnam Shariati, Mohammadreza Shalbafan, Vahid Rashedi, Masoomeh Yarahmadi, Alireza Ghaznavi and Shayan Amiri Tags: Research Source Type: research
Quality assessment of different brands of atorvastatin tablets available in Riyadh, Saudi Arabia
Hypolipidemic agents have been shown to be helpful in the primary and secondary prevention of cardiovascular disease. Most often, statins are prescribed to treat hyperlipidemia. There are a number of statins a... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 13, 2022 Category: Drugs & Pharmacology Authors: Ali AlMuhsin, Abdul Ahad, Yousef A. Bin Jardan, Mohammad Raish, Ajaz Ahmad, Khalid M. Alkharfy and Fahad I. Al-Jenoobi Tags: Research Source Type: research
Correction: Utility of support vector machine and decision tree to identify the prognosis of metformin poisoning in the United States: analysis of National Poisoning Data System
An amendment to this paper has been published and can be accessed via the original article. (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 9, 2022 Category: Drugs & Pharmacology Authors: Omid Mehrpour, Farhad Saeedi, Christopher Hoyte, Foster Goss and Farshad M. Shirazi Tags: Correction Source Type: research
Prediction of mortality and morbidity following paraquat poisoning based on trend of liver and kidney injury
Paraquat is a non-selective herbicide that causes severe tissue damage in various organs including the liver and kidney. The aim of this study was to determine the trend of the liver and kidney injury in patie... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 6, 2022 Category: Drugs & Pharmacology Authors: Farzad Gheshlaghi, Jamileh Haghirzavareh, Anselm Wong, Parastoo Golshiri, Shayan Gheshlaghi and Nastaran Eizadi-Mood Tags: Research Source Type: research
Effects of rosuvastatin on serum glucose and insulin in hyperuricemic rats
This study was to determine the roles of rosuvastatin in fasting blood glucose (FGB) and insulin levels in hyperuricemic rats. (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 5, 2022 Category: Drugs & Pharmacology Authors: Dilidaer Xilifu, Zumulaiti Tuerxun, Buweiayixiemu Nuermaimaiti, Ayinu Aili, Nijiati Rehemu, Huiping Sun and Xiangyang Zhang Tags: Research Source Type: research
Raltitrexed regulates proliferation and apoptosis of HGC-27 cells by upregulating RSK4
In this study, we investigated the effect of raltitrexed on the ... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 28, 2022 Category: Drugs & Pharmacology Authors: Cong Hu, Xinhua Chen, Xu Lin, Jun Dai and Jiang Yu Tags: Research Source Type: research
Practical approaches to improve vancomycin-related patient outcomes in pediatrics- an alternative strategy when AUC/MIC is not feasible
Anecdotal experience and studies have shown that most pediatric patients fail to reach target therapeutic vancomycin trough levels (VTLs) and required higher total daily doses (TDD). This retrospective study a... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 20, 2022 Category: Drugs & Pharmacology Authors: Kashif Hussain, Muhammad Sohail Salat, Shahzad Rauf, Manoj Rathi, Midhat Khan, Fizzah Naz, Wasif Ahmed Khan, Rahila Ikram and Gul Ambreen Tags: Research Source Type: research
Dexamethasone suppresses the proliferation and migration of VSMCs by FAK in high glucose conditions
High glucose conditions cause some changes in the vessels of diabetes through the signal transduction pathways. Dexamethasone and other corticosteroids have a wide range of biological effects in immunological ... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 17, 2022 Category: Drugs & Pharmacology Authors: Ali Akbar Soleimani, Asghar Mohammadi, Ghasem Ghasempour, Borhan Rahimi Abkenar, Nafiseh Shokri and Mohammad Najafi Tags: Research Source Type: research
Pharmacovigilance of cutaneous adverse drug reactions in associations with drugs and medical conditions: a retrospective study of hospitalized patients
This study aimed to investigate the correlation between clinical drug application and CADR occurrence as evidence for preventi... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 10, 2022 Category: Drugs & Pharmacology Authors: Lei Zheng, Hao-bin Jin, Yu-yao Guan and Jing Yang Tags: Research Source Type: research
Fluvastatin promotes chondrogenic differentiation of adipose-derived mesenchymal stem cells by inducing bone morphogenetic protein 2
Adipose-derived mesenchymal stem cells (ADMSCs) are a promising source of material source for medical regeneration of cartilage. Growth factors, including transforming growth factor- β (TGFβ) subfamily members ... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 9, 2022 Category: Drugs & Pharmacology Authors: Masanari Kuwahara, Yukio Akasaki, Norio Goto, Ichiro Kurakazu, Takuya Sueishi, Masakazu Toya, Taisuke Uchida, Tomoaki Tsutsui, Ryota Hirose, Hidetoshi Tsushima and Yasuharu Nakashima Tags: Research article Source Type: research
Self-medication practices and their characteristics among Iranian university students
Self-medication in students, as educated people, is one of the most important health issues. It is known that inappropriate self-medication is harmful for individuals as it has potential risks, disrupts the dr... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 8, 2022 Category: Drugs & Pharmacology Authors: Rohaneh Rahimisadegh, Nader Sharifi, Vahid Kohpeima Jahromi, Razieh Zahedi, Zahra Rostayee and Razieh Asadi Tags: Research Source Type: research
Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study
Testicular torsion is a pathological condition which needs emergency surgical intervention. However, after surgical reperfusion, oxidative stress factors cause to germ cell apoptosis. The study was planned to ... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 5, 2022 Category: Drugs & Pharmacology Authors: Iraj Yazdani, Raheleh Majdani, Morteza Ghasemnejad-berenji and Ahmad Reza Dehpour Tags: Research Source Type: research
Pharmacological evaluation of newly synthesized organotin IV complex for antiulcer potential
The present study aims to investigate the newly synthesized organotin (IV) complex (2E, 2 ′E) dibutylstannanediyl bis (4-(4-nitrophenyl) amino)-4-oxobut-2-enoate (DTN) for its anti-ulcer potential. Characteriza... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - July 29, 2022 Category: Drugs & Pharmacology Authors: Syed Azmatullah, Arif-ullah Khan, Neelam Gul Qazi, Humaira Nadeem and Nadeem Irshad Tags: Research Source Type: research
