The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's disease: a systematic review and meta-analysis
Botulinum toxin (BoNT) injection is an important adjunctive method to treat sialorrhea. The purpose of this systematic review was to analyze the effect and safety of BoNT injections in the intervention of sial... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - October 12, 2023 Category: Drugs & Pharmacology Authors: Chun-Lan Yang, Jia-Peng Huang, Ying-chao Tan, Ting-ting Wang, Han Zhang and Yun Qu Tags: Research Source Type: research
Correction to: efficacy and safety of the switch of Triumeq ® to generic (abacavir + lamivudine) + Tivicay®: data at 24 weeks
(Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - October 6, 2023 Category: Drugs & Pharmacology Authors: Juli án Olalla, Javier Pérez-Stachowski, Begoña Tortajada, Alfonso Del Arco, Efrén Márquez, Javier De la Torre, Miriam Nieto, José María García de Lomas, José Luis Prada and Javier García-Alegría Tags: Correction Source Type: research
Butyrate alleviates renal inflammation and fibrosis in a rat model of polycystic ovarian syndrome by suppression of SDF-1
Polycystic ovarian syndrome (PCOS) is a multifactorial condition with metabolic-related complications, such as diabetic nephropathy and chronic renal disorder, which are the leading cause of renal transplant g... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - October 3, 2023 Category: Drugs & Pharmacology Authors: Al-Amin M. Bashir and Kehinde S. Olaniyi Tags: Research Source Type: research
Population pharmacokinetic analysis of lopinavir in HIV negative individuals exposed to SARS-CoV-2: a COPEP (COronavirus Post-Exposure Prophylaxis) sub-study
Lopinavir/ritonavir (LPV/r) is a drug traditionally used for the treatment of HIV that has been repurposed as a potential post-exposure prophylaxis agent against COVID-19 in the COronavirus Post-Exposure Proph... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 27, 2023 Category: Drugs & Pharmacology Authors: Paul Thoueille, Margot Delfraysse, Pascal Andre, Thierry Buclin, Laurent A. Decosterd, Chiara Fedeli, Pilar Ustero, Alexandra Calmy and Monia Guidi Tags: Research Source Type: research
Bilirubin potentiates etomidate-induced sedation by enhancing GABA-induced currents after bile duct ligation
Our previous clinical trial showed that etomidate requirements to reach an appropriate level of anesthesia in patients with obstructive jaundice were reduced, which means that these patients are more sensitive... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 23, 2023 Category: Drugs & Pharmacology Authors: Hao Gao, Qian Zhao, Jian-Gang Song, Guo-Xia Hu, Wei-Feng Yu, Ying-Fu Jiao and Jin-Chao Song Tags: Research article Source Type: research
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway
The study aims to investigate the apoptotic effects of combining LBH589 and AM1241 (a selective CB2 receptor agonist) on cervical cancer cells and elucidating the mechanism of this combined therapy, which may ... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 22, 2023 Category: Drugs & Pharmacology Authors: Bo Sheng, Wenwen Wang, Dongyue Xia and Xiangdong Qu Tags: Research Source Type: research
Core decompression combined with local DFO administration loaded on polylactic glycolic acid scaffolds for the treatment of osteonecrosis of the femoral head: a pilot study
In this study, we evaluated the outcome of ONFH treated wi... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - September 5, 2023 Category: Drugs & Pharmacology Authors: Kaveh Gharanizadeh, Ali Mohammad Sharifi, Hamed Tayyebi, Razieh Heidari, Shayan Amiri and Sajad Noorigaravand Tags: Research Source Type: research
Drugs and gut microbiome interactions —an emerging field of tailored medicine
Gut dwelling microbes provide profound biochemical advantages to the host, including nutrient and drug absorption, metabolism, and excretion. It is an emerging understanding that drug-response bias (particular... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 30, 2023 Category: Drugs & Pharmacology Authors: Imran Khan Tags: Editorial Source Type: research
Berberine-loaded albumin nanoparticles reverse aflatoxin B1-induced liver hyperplasia
Hepatocellular carcinoma (HCC) can be produced from aflatoxin B1 (AFB1) administration. Although berberine (BER) acts as an anticancer agent and can counteract the AFB1 effect, it has low bioavailability. Nano... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 10, 2023 Category: Drugs & Pharmacology Authors: Sarah M. Khedr, Doaa A. Ghareeb, Shadia A. Fathy and Germine M. Hamdy Tags: Research Source Type: research
Medication overdose data analysis: a review of medication error reports in the FDA adverse event reporting system (FAERS)
drug overdose is a common type of medication error, which caused significant patient injuries and economic losses. To determine which drugs are reported most frequently in association with drug overdose, a com... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - August 4, 2023 Category: Drugs & Pharmacology Authors: Jiaqi Ni, Xinru Tang and Li Chen Tags: Research Source Type: research
Retraction Note: Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout
(Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - July 12, 2023 Category: Drugs & Pharmacology Authors: Zakir Ali, Fakhar ud Din, Fatima Zahid, Saba Sohail, Basalat Imran, Salman Khan, Maimoona Malik, Alam Zeb and Gul Majid Khan Tags: Retraction Note Source Type: research
Retraction Note: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s40360-019-0335-5. (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - June 30, 2023 Category: Drugs & Pharmacology Authors: Ruqayya Afridi, Ashraf Ullah Khan, Sidra Khalid, Bushra Shal, Hina Rasheed, Muhammad Zia Ullah, Omer Shehzad, Yeong Shik Kim and Salman Khan Tags: Retraction Note Source Type: research
Efficacy and safety of proxalutamide (GT0918) in severe or critically ill patients with COVID-19: study protocol for a prospective, open-label, single-arm, single-center exploratory trial
The rapid worldwide spread of COVID-19 has caused a global health challenge with high mortality of severe or critically ill patients with COVID-19. To date, there is no specific efficient therapeutics for seve... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - June 15, 2023 Category: Drugs & Pharmacology Authors: Dawei Yang, Minjie Ju, Hao Wang, Yichen Jia, Xiaodan Wang, Hao Fang and Jia Fan Tags: Study protocol Source Type: research
Longitudinal follow-up of zearalenone and deoxynivalenol mycotoxins in breast milk in the first five months of life
This study aimed to determine the levels and changes of Zearalenone (ZEN), Deoxynivalenol (DON) mycotoxins f... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - May 30, 2023 Category: Drugs & Pharmacology Authors: B ülent Güneş, Suzan Yalçın and Sıddika Songül Yalçın Tags: Research Source Type: research
A phase I study comparing the biosimilarity of the pharmacokinetics and safety of recombinant humanized anti-vascular endothelial growth factor monoclonal antibody injection with Avastin ® in healthy Chinese male subjects
The biosimilar landscape for malignancies continues to grow, with several biosimilars for reference product bevacizumab currently available. Bevacizumab has been shown to be well tolerated; however, the safety... (Source: BMC Clinical Pharmacology)
Source: BMC Clinical Pharmacology - May 27, 2023 Category: Drugs & Pharmacology Authors: Hongtao Li, Xiangdi Zhao, Jing Xie, Xingyu Zhu, Yue Su, Cuixia He, Jiaxiang Ding, Minhui Zhu, Yuanyuan Xu, Ying Wang, Rongfang Shan, Bingyan Liu, Yuzhou Ding, Yuanyuan Liu, Huan Zhou and Yunqiu Xie Tags: Research Source Type: research
