Fight Aging! Newsletter, April 6th 2020
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted.
Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - April 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fasting Accelerates Wound Healing in Mice
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted.
Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - April 3, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
ALPHASTROKE, A Better Way to Diagnose Strokes: Interview with CEO Matt Kesinger
Strokes affect nearly 800,000 Americans per year. One of the most important prognostic factors is the time from symptom onset to treatment. Currently, strokes are usually diagnosed by first-responders using a quick physical exam — a subjective method that can result in incorrect diagnoses, delayed treatment, and poor outcomes.
Forest Devices hopes to change that. The Pittsburgh-based company’s product, ALPHASTROKE, is a portable triage tool that allows first-responders to diagnose strokes more accurately than with a conventional clinical exam. The company’s studies have shown that ALPHASTROKE can diagnose stro...
Source: Medgadget - February 25, 2020 Category: Medical Devices Authors: Cici Zhou Tags: Diagnostics Neurology Source Type: blogs
Wearable Magnetic Stimulator for Stroke Recovery
Stroke can result in a variety of debilitating conditions caused by damaged neural connections within the brain. Researchers at the Eddy Scurlock Stroke Center at Houston Methodist Hospital in Texas have now successfully tested a wearable, multifocal, transcranial, rotating, permanent magnet stimulator (TRPMS) to boost neural activity near injured brain areas in patients recovering from a stroke.
The trial involved 30 patients, half of whom were treated with TRPMS and the other half received a sham treatment. All had weakness on one side of the body three months following their strokes. The treated patients underwent tw...
Source: Medgadget - February 25, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Neurology Rehab Source Type: blogs
World ’s First Portable MRI Cleared by FDA
Magnetic resonance imaging (MRI) has revolutionized medicine, but MRI scanners are so demanding that access to them is still a challenge. MRI machines typically require specially built rooms with magnet quench vent pipes, entry systems that check people for metals attracted to magnets, and specific protocols to ensure safety. Patients, therefore, have to be brought to the MRI scanners rather than the other way around.
This is about to change in many cases, as Hyperfine, a company with offices in New York City and St Guilford, Connecticut, won FDA clearance for the first MRI scanner that can be wheeled to the patient bed...
Source: Medgadget - February 17, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Emergency Medicine Neurology Neurosurgery Radiology Source Type: blogs
Fight Aging! Newsletter, January 27th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - January 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A young woman with epigastric pain. ECG Crochetage sign? What is the significance?
A former resident texted me this ECG, done for epigastric pain in an 18 year old. The pain resolved immediately with treatment for acid reflux, and in the clinician ' s opinion was clearly GI in origin, but he wanted to know what the strange waves in the QRS were:See the unusual notching in II, III, aVF, and V2-V4.I had no idea what they were. They reminded me of theDelayed Activation Wave associated with circumflex acute MI.See this case: https://hqmeded-ecg.blogspot.com/2018/05/is-there-delayed-activation-wave.html.But they are clearly different from this.I put it on Facebook EKG club and this is th...
Source: Dr. Smith's ECG Blog - January 7, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs
Cardiology MCQ – Warfarin for nonvalvular AF – Answer
Cardiology MCQ – Warfarin for nonvalvular AF – Answer
Warfarin given in patients with nonvalvular atrial fibrillation (AF) can reduce ischemic stroke by — %:
Correct Answer: 3. 60%
A meta analysis of 29 trials including a total of 28,044 participants showed that warfarin reduced stroke by 64% while antiplatelet agents reduced stroke by 22% in those with nonvalvular atrial fibrillation. Absolute increase in major extracranial hemorrhages was 0.3% or lesser in this meta analysis.
Back to question
Reference
Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients ...
Source: Cardiophile MD - December 16, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Cardiology MCQ – Warfarin for nonvalvular AF
Cardiology MCQ – Warfarin for nonvalvular AF
Warfarin given in patients with nonvalvular atrial fibrillation (AF) can reduce ischemic stroke by — %:
20%
40%
60%
80%
Post your answer as a comment below. (Source: Cardiophile MD)
Source: Cardiophile MD - December 16, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Flashcards: Hidden Powers | Episode 58
If you think you know flashcards, think again. Host Kevin Patton outlines the learning science behind flashcards, then shows how they can go way beyond simple memorization in the first of a multipart series on the hidden powers of flashcards. Updates in gene therapy to grow brain cells and smelling without olfactory bulbs.01:12 | Gene Therapy for Brain Cells04:05 | Sponsored by HAPS04:49 | Something Smells Odd08:26 | Sponsored by AAA08:45 | Introduction to Flashcards21:03 | Sponsored by HAPI Online Graduate Program21:45 | Beginning Intermediate Flashcards34:31 | Staying ConnectedIf you cannot see or activate...
Source: The A and P Professor - December 15, 2019 Category: Physiology Authors: Kevin Patton Source Type: blogs
Fight Aging! Newsletter, December 9th 2019
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - December 8, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Prospects for Restoring Neurogenesis in the Aging Brain
Today's open access paper is a review of potential approaches that might be used as a basis for therapies to restore a more youthful level of neurogenesis in the aging mammalian brain. Neurogenesis is the process by which new neurons are created by neural stem cell populations and then integrated into neural networks. In adults, neurogenesis is essential to memory, learning, and the limited degree of regeneration that the brain is capable of enacting. Unfortunately, the supply of new neurons declines with age as the underlying stem cells become ever less active. Beyond making the aging brain more resilient, methods of incr...
Source: Fight Aging! - December 4, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Maternal Mortality – Separating Signal from Noise
By AMEYA KULKARNI, MD
When Samuel Morse left his New Haven home to paint a portrait of the
Maquis du Lafayette in Washington DC, it was the last time he would see his
pregnant wife. Shortly after his arrival in Washington, his wife developed
complications during childbirth. A messenger took several days on horseback to
relay the message to Mr Morse. Because the trip back to New Haven took several
more, his wife had died by the time he arrived at their home. So moved was he by the tragedy of lost time
that he dedicated the majority of the rest of his life to make sure that this
would never happen to anyone again. H...
Source: The Health Care Blog - December 3, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Medical Practice Ameya Kulkarni Global Health Maternal mortality public health Source Type: blogs
Nanoparticles Cross Blood-Brain Barrier to Treat Stroke
Ischemic strokes can cause havoc in the brain, but early and properly directed treatment can mitigate a lot of damage. While there are a number of options to unclog blocked arteries, the potential to provide additional drug therapy remains mostly unexplored because of the difficulty in getting medications past the blood-brain barrier.
Now, researchers at the University of Manchester are reporting that they were able to pass liposomes across the tiny tears in the vasculature that occur during ischemic strokes. Liposomes are lipid vesicles, naturally produced by the body and easily made in the lab, that are only about 100...
Source: Medgadget - November 7, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Critical Care Emergency Medicine Materials Nanomedicine Neurology Neurosurgery Source Type: blogs
A man in his 50s with witnessed arrest and ST elevation in aVR
Written by Meyers, edits by SmithA 50-ish year old man was working construction when he suddenly collapsed. Coworkers started CPR within 1 minute of collapse. EMS arrived within 10 minutes and continued CPR and ACLS, noting alternating asystole and sinus bradycardia during rhythm checks. He received various ACLS medications and arrived at the ED with a perfusing rhythm.Initial vitals included heart rate around 100 bpm and BP 174/96. Here is his initial ECG, very soon after ROSC:What do you think?Sinus tachycardia. There is incomplete RBBB (QRS duration less than 120 ms). There is diffuse STD, maximal in V4-V5 a...
Source: Dr. Smith's ECG Blog - November 2, 2019 Category: Cardiology Authors: Pendell Source Type: blogs
