TIGERTRIEVER 13, World ’s Smallest Clot Retriever for Strokes, Cleared in Europe
Rapid Medical, based in Yokneam, Israel, won European regulatory approval to introduce its TIGERTRIEVER 13, the narrowest clot retriever now available for use in treating ischemic stroke. The device can be used in vessels as small as 1 millimeter in width and up to a maximum of 2.5 mm, where larger retrievers would be appropriate. It works through a microcatheter that has an outside diameter of 1.3 French, getting into brain vasculature previously impossible to access. Unlike many existing devices, the entire TIGERTRIEVER is visible under fluoroscopy. It does feature radiopaque markers that make positioning and measure...
Source: Medgadget - August 7, 2018 Category: Medical Devices Authors: Editors Tags: Neurology Neurosurgery Radiology Vascular Surgery Source Type: blogs

EMBOTRAP II Clot Retriever Now Saving People from Ischemic Strokes in U.S.
CERENOVUS, a part of Johnson & Johnson, is reporting that its EMBOTRAP II clot retriever has been used commercially for the first time in the U.S. to reverse an ischemic stroke. The catheter-delivered device is able to securely grab onto the clot without squeezing it too hard, allowing the physician to manipulate the thrombus as a whole. This can prevent downstream damage if chunks of the clot come off the main piece. The device is intended to be used within eight hours of initial stroke symptoms. Some recent results of a study evaluating the effectiveness of the EMBOTRAP II, according to CERENOVUS: In the ARISE II (...
Source: Medgadget - July 30, 2018 Category: Medical Devices Authors: Editors Tags: Neurology Neurosurgery Radiology Source Type: blogs

Is Medical Imaging a Ricardian ” Derived Demand ” ?
By SAURABH JHA Medical Imaging and the Price of Corn After the Napoleonic wars, the price of corn in England became unaffordable. The landowners were blamed for the high price, which some believed was a result of the unreasonably high rents for farm land. Economist David Ricardo disagreed. According to Ricardo, detractors had the directionality wrong. It was the scarcity of corn (the high demand relative to its supply) that induced demand for the most fertile land. That is, the rent did not increase the price of corn. The demand for corn raised the rent. Rent was a derived demand. Directionality is important. Getting direc...
Source: The Health Care Blog - July 21, 2018 Category: Consumer Health News Authors: at RogueRad Tags: Uncategorized Source Type: blogs

Is Medical Imaging a Ricardian Derived Demand?
By SAURABH JHA Medical Imaging and the Price of Corn After the Napoleonic wars, the price of corn in England became unaffordable. The landowners were blamed for the high price, which some believed was a result of the unreasonably high rents for farm land. Economist David Ricardo disagreed. According to Ricardo, detractors had the directionality wrong. It was the scarcity of corn (the high demand relative to its supply) that induced demand for the most fertile land. That is, the rent did not increase the price of corn. The demand for corn raised the rent. Rent was a derived demand. Directionality is important. Getting direc...
Source: The Health Care Blog - July 21, 2018 Category: Consumer Health News Authors: at RogueRad Tags: Uncategorized Source Type: blogs

How dangerous are NSAIDs in patients with AF?
One of the most commonly asked questions in the office is the treatment of arthritis pain. This comes up because of the concern over taking NSAIDs (non steroidal anti-inflammatory drugs) in patients who are on anticoagulants (such as warfarin, or dabigatran, rivaroxaban, apixaban). My views on this matter have changed. But first, I want to mention a study published in JACC that addressed the issue of NSAID use in pts with AF who take an anticoagulant. This was a sub-analysis of the RELY trial, which pitted dabigatran vs warfarin. Remember, in the original RELY trial, the 150mg dose of dabigatran did better than warfarin at...
Source: Dr John M - July 13, 2018 Category: Cardiology Authors: Dr John Source Type: blogs

The Evidence Crisis: Causal Inference – Don ’ t be a chicken (Part 3)
By ANISH KOKA Part 1 Part 2 Physicians have been making up numbers longer than people have been guessing weights at carnivals.  How much does this statin lower the chances of a heart attack? How long do I have to live if I don’t get the aortic valve surgery? In clinics across the land confident answers emerge from doctors in white coats.  Most of the answers are guesses based on whatever evidence about the matter exists applied to the patient sitting in the room.  The trouble is that the evidence base used to be the provenance of experts and anecdotes that have in the past concluded leeches were good for pneumonia...
Source: The Health Care Blog - June 29, 2018 Category: Consumer Health News Authors: anish_koka Tags: Uncategorized Source Type: blogs

LITFL Review 335
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 335th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM. Readers can subscribe to LITFL review RSS or LITFL review EMAIL subscription The Most Fair Dinkum Ripper Beauts of the Week Can a slower ap...
Source: Life in the Fast Lane - June 10, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: LITFL review LITFL R/V Source Type: blogs

Patient with Paced Rhythm in Severe Cardiomyopathy Presents with SOB due to Acute Decompensated Heart Failure
This is a middle-aged male with h/o with a history ofheart failure with severely reducedejection fraction due to dilated ischemic cardiomyopathy (EF 5-10%), probably with some component of non-ischemic cardiomyopathy, with h/o CABG, who is status post ICD placement (and previous appropriate shocks for VT) and biventricular pacer ( " cardiac resynchronization therapy " ), who is on amiodarone for VT suppression, and has h/o LV thrombus and is on chronicanticoagulation with warfarin.He presented forparoxysmal nocturnal dyspnea that didn ' t resolve with use of his home prn diuretics.  He was hyp...
Source: Dr. Smith's ECG Blog - June 9, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs

As CABANA waves a final good bye to catheters in AF . . . let the pulmonary veins rejoice !
There is a tough ongoing rivalry between drugs and catheters to conquer the commonest electrical chaos in human heart, namely Atrial fibrillation (AF). Mind you,the confusion about the importance of this arrhythmia is huge and real.Bulk of these episodes are transient , paroxysmal and do not require rigorous management.While stroke prevention seems to be the major aim and target , the real world scenario seems to tell  a different story. The nomenclature conundrum  AF may be classified as many ways a learned cardiologists can think . Often it’s done with reference to etiology, duration , rate, neural (sympathetic o...
Source: Dr.S.Venkatesan MD - May 31, 2018 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized ACC AHA ESC guidelines for AF affirm race cabana amiodarone for atrial fibrillation CABANA trial carto pulmonary vein ablations cryo balloon for af ablation heart rhythm society atrial fibrillation guidelines rate vs rhythm c Source Type: blogs

LITFL Review 333
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 333rd LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM. Readers can subscribe to LITFL review RSS or LITFL review EMAIL subscription The Most Fair Dinkum Ripper Beauts of the Week This is an abso...
Source: Life in the Fast Lane - May 27, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: LITFL review LITFL R/V Source Type: blogs

Heart disease in pregnancy: Risk stratification
It is needless to say that heart disease in pregnancy is a challenge for the obstetrician and the cardiologist. Hemodynamic changes in pregnancy and labour can adversely affect many of the significant cardiac lesions. Increase in blood volume and heart rate are the important factors during pregnancy. In general stenotic lesions and pulmonary hypertension are poorly tolerated, while regurgitant lesions are better tolerated. Specific risks like aortic dissection and rupture are there for coarctation of aorta. Several risk stratification schemes have been developed for assessing the risk of pregnancy with heart disease over ...
Source: Cardiophile MD - May 27, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology CARPREG II risk scoring CARPREG risk stratification mWHO classification ZAHARA risk score Source Type: blogs

EMBOTRAP II Pulls Clots from Brain With Minimal Compression: FDA Cleared
CERENOVUS, a Johnson & Johnson company that was built by combining Pulsar Vascular, Neuravi, and Codman Neuro’s neurological business, won FDA clearance for the EMBOTRAP II Revascularization Device. The stent retriever is used to pull blood clots from the brain, restoring blood flow and hopefully preventing the terrible consequences of a stroke. The device, intended to be used within eight hours of initial stroke symptoms, is designed to apply as little pressure on the clot as possible in an attempt to avoid breaking it up into smaller parts, while confidently grabbing it to make sure it is removed completely. He...
Source: Medgadget - May 24, 2018 Category: Medical Devices Authors: Editors Tags: Neurology Neurosurgery Radiology Source Type: blogs

Fight Aging! Newsletter, April 23rd 2018
In conclusion, a debate exists on whether aging is a disease in itself. Some authors suggest that physiological aging (or senescence) is not really distinguishable from pathology, while others argue that aging is different from age-related diseases and other pathologies. It is interesting to stress that the answer to this question has important theoretical and practical consequences, taking into account that various strategies capable of setting back the aging clock are emerging. The most relevant consequence is that, if we agree that aging is equal to disease, all human beings have to be considered as patients to be treat...
Source: Fight Aging! - April 22, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Delivery of Exosomes Improves Recovery from Stroke in Pigs
This study, coupled with our previously published studies focused on a mouse model, represents the first time that a company demonstrated proof-of-concept of the therapeutic potential of extracellular vesicles in two divergent animal species and two stroke types - embolic and ischemic." This is the third study recently completed by ArunA, the first two of which demonstrated improved outcomes in middle-aged and aged mice following embolic stroke. Study results showed NSC EV treatment: was neuroprotective; eliminated intracranial hemorrhage in ischemic lesions; improved behavior and mobility; decreased cerebral infarc...
Source: Fight Aging! - April 16, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs