GORE CARDIOFORM Septal Occluder Approved by FDA for PFO Closure
The FDA has approved the GORE CARDIOFORM Septal Occluder for patent foramen ovale (PFO) closure procedures that have shown to reduce the chance of stroke in some patients. The CARDIOFORM is already being used in the U.S. for closing of atrial septal defects up to 17 millimeters in size.
The catheter-delivered device consists of two discs that make contact with the tissue walls on both sides of the PFO and come together to block the passage of blood between the atria.
“The soft and conformable design of Gore’s device is ideal for providing long-term repair of PFOs of any shunt size,” said John Rhodes, MD, Medical...
Source: Medgadget - April 6, 2018 Category: Medical Devices Authors: Editors Tags: Cardiac Surgery Cardiology Radiology Source Type: blogs
LITFL Review 325
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 325th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
Readers can subscribe to LITFL review RSS or LITFL review EMAIL subscription
The Most Fair Dinkum Ripper Beauts of the Week
The New York T...
Source: Life in the Fast Lane - April 2, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
Fight Aging! Newsletter, March 26th 2018
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - March 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
LITFL Review 322
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 322nd LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
The Intensive Care Network have more podcasts from the CICM ASM. A new batch focusing on live...
Source: Life in the Fast Lane - March 11, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
The Prospects for Enhancing Repair Systems in the Brain to Treat Stroke Patients
A sizable fraction of the regenerative medicine community is interested in finding ways to improve existing repair systems in the body, and particularly in the central nervous system, which exhibits little ability to recover from injury in mammals. Initiatives in progress include efforts to increase the rate at which new neurons are created and integrated into the brain, work on ways to encourage more glial cells to adopt a pro-regenerative state, and the usual range of approaches based on delivering signal molecules found to be significant in stem cell therapies or heterochronic parabiosis studies. This open access review...
Source: Fight Aging! - March 5, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Tetramethylpyrazine is Senolytic in Bone Marrow: Reduces Inflammation and Improves Stem Cell Function in Mice
In this study, we aimed to investigate the local effect of TMP on the bone marrow of aging mice and to determine whether the senescent phenotype of MSCs could be eliminated. Our findings revealed that local delivery of TMP eliminates the senescent phenotype of LepR+ MSCs via epigenetically modulating (Source: Fight Aging!)
Source: Fight Aging! - March 3, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Shoulder pain after lifting a heavy box
Written by Pendell Meyers, edits by Steve SmithThis will be too easy for most long-time readers, but if you are at that level, sit back and enjoy noticing how few milliseconds it takes to recognize this thanks to so many prior examples on this blog!I was sent this ECG from EMS with only the information that it belonged to a middle aged male with left shoulder pain.What do you think?There are hyperacute T-waves in leads V1-V6, as well as in leads II, III, aVF. The J-points are all at baseline with the exception of leads V2-V3 which show a small amount of STD (which makes de Winter morphology in the presence of hyperacute T-...
Source: Dr. Smith's ECG Blog - February 22, 2018 Category: Cardiology Authors: Pendell Source Type: blogs
Fight Aging! Newsletter, February 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - February 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Coala Heart Monitor – The Swedish Response To The ECG Revolution
It has never been easier to measure ECG and monitor heart health at home. New pocket-sized gadgets, chest straps, even specialized earbuds promise accurate measurements during sports activity, cooking or watching TV at home. AliveCor’s Kardia, MocaCare, Skeeper, just to name a few digital devices The Medical Futurist already reviewed. Recently, a Swedish company sent me their version and I eagerly tested it. Let’s see what the Coala Heart Monitor can offer.
The ECG Revolution
A real revolution started in cardiology: miniaturized and patient-friendly designs of ECG monitors, single- and multi-channel ECGs arrive on the ...
Source: The Medical Futurist - February 13, 2018 Category: Information Technology Authors: nora Tags: Health Sensors & Trackers digital health ecg future Healthcare Innovation Personalized medicine review technology Source Type: blogs
2018 AHA/ASA stroke guidelines & Radiology
The following are key points to remember from the American Heart Association (AHA)/American Stroke Association (ASA) 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke:These 2018 guidelines are an update to the 2013 guidelines, which were published prior to the six positive “early window” mechanical thrombectomy trials that emerged in 2015 and 2016 showed a clear benefit of“extended window” mechanical thrombectomy for certain patients with large vessel occlusion who could be treated out to 16-24 hours IV tPA should be administered to all eligible acute stroke patients within 3 hour...
Source: Sumer's Radiology Site - February 4, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs
LITFL Review 316
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 316th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
Ercast’s Rob Orman from sits down with performance coach Jason Brooks to discuss performanc...
Source: Life in the Fast Lane - January 28, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
Fight Aging! Newsletter, January 29th 2018
In conclusion, the present study demonstrated that TIGIT is a prominent negative immune regulator involved in immunosenescence. This novel finding is highly significant, as targeting TIGIT might be an effective strategy to improve the immune response and decrease age-related comorbidities.
Delivery of Extracellular Vesicles as a Potential Basis for Therapies
https://www.fightaging.org/archives/2018/01/delivery-of-extracellular-vesicles-as-a-potential-basis-for-therapies/
Here I'll point out a readable open access review paper on the potential use of extracellular vesicles as a basis for therapy: harvest...
Source: Fight Aging! - January 28, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Chest pain, sinus tachycardia, and ST Elevation
I was reading through ECGs on the system when I saw this one:Sinus tachycardia, rate 120Computerized QTc = 380 msWhat do you think? I was immediately worried about a proximal LAD occlusion. Although sinus tachycardia generally argues against ACS, a large anterior MI may result in such poor stroke volume that there is compensatory tachycardia and possibly impending cardiogenic shock. I looked to see if there was an ED cardiac ultrasound, and there was:Parasternal Long Axis:Poor image, but one can see that there is poor apical functionParasternal short axis:This shows poor contractility of the anterior wall.C...
Source: Dr. Smith's ECG Blog - January 22, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs
Specific Risk Factors can Appear to Decline in Importance in Later Life, as the High-Risk Individuals are Already Dead
As this 40-year longitudinal study illustrates, when measuring the correlation between specific risk factors on specific forms of mortality, their influence can appear to decline in later life. That is to say that mortality rates keep rising with advancing age, but they are less obviously influenced by any one cause for a given cohort of individuals. This effect occurs because the fatal consequences of a particular form of age-related dysfunction will tend to occur earlier in old age for individuals with the highest risk. With each passing year, a given age group is ever more made up of resilient survivors, people who - fo...
Source: Fight Aging! - January 9, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Risk factors which can affect the outcome of CABG
(Coronary Artery Bypass Grafting)
Age and gender: advanced age and female gender have less favourable outcome.
Previous cardiovascular events: prior cardiovascular surgery, interventions, myocardial infarction, stroke or transient ischemic attacks.
Cardiovascular variables: left ventricular function, hypertension, cardiac arrhythmias.
Diabetes mellitus, chronic renal disease, chronic obstructive pulmonary disease.
Complexity of disease: number of vessels involved, severity of associated valvular stenosis or regurgitation and endocarditis if any.
Hemodynamic status and urgency of surgery.
Pulmonary hypertensi...
Source: Cardiophile MD - January 6, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiac Surgery Source Type: blogs
