Evaluating the predictive value of a coagulation-related gene model in glioma
CONCLUSION: This study established the correlation between the coagulation-related gene model and glioma prognosis, providing deeper insight into the mechanism and treatment of glioma.PMID:38650572 | DOI:10.5137/1019-5149.JTN.45238-23.2 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Ming Cao Jie Chen Rong-Zeng Guo Source Type: research
Non-Detection of HCMV Total Genomic DNA in Human Glioma Cells Genome
CONCLUSION: We found that the genomic DNA of all the samples was negative for HCMV genomic DNA. Thus, HCMV could not be detected in human glioma tumors and we put forward that HCMV genomic DNA was not incorporated into the genomic DNA of glioma cells. Thus, total viral DNA is not involved in the pathogenesis of glioma; however, small viral particles or specific genes might be incorporated into the genomic DNA of glioma cells, leading to cancer development. This prompts further studies for verification.PMID:38650560 | DOI:10.5137/1019-5149.JTN.42717-22.1 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Dilek Gokturk Meryem Damla Ozdemir Dervis Mansuri Yilmaz Source Type: research
Diffusion- and Perfusion-Weighted MRI Radiomics for Survival Prediction in Patients with Lower-Grade Gliomas
CONCLUSION: Adding diffusion- and perfusion-weighted MRI radiomics to clinical features improved survival prediction in lower-grade glioma.PMID:38653567 | PMC:PMC11045349 | DOI:10.3349/ymj.2023.0323 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Chae Jung Park Sooyon Kim Kyunghwa Han Sung Soo Ahn Dain Kim Yae Won Park Jong Hee Chang Se Hoon Kim Seung-Koo Lee Source Type: research
Evaluating the predictive value of a coagulation-related gene model in glioma
CONCLUSION: This study established the correlation between the coagulation-related gene model and glioma prognosis, providing deeper insight into the mechanism and treatment of glioma.PMID:38650572 | DOI:10.5137/1019-5149.JTN.45238-23.2 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Ming Cao Jie Chen Rong-Zeng Guo Source Type: research
Non-Detection of HCMV Total Genomic DNA in Human Glioma Cells Genome
CONCLUSION: We found that the genomic DNA of all the samples was negative for HCMV genomic DNA. Thus, HCMV could not be detected in human glioma tumors and we put forward that HCMV genomic DNA was not incorporated into the genomic DNA of glioma cells. Thus, total viral DNA is not involved in the pathogenesis of glioma; however, small viral particles or specific genes might be incorporated into the genomic DNA of glioma cells, leading to cancer development. This prompts further studies for verification.PMID:38650560 | DOI:10.5137/1019-5149.JTN.42717-22.1 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Dilek Gokturk Meryem Damla Ozdemir Dervis Mansuri Yilmaz Source Type: research
Diffusion- and Perfusion-Weighted MRI Radiomics for Survival Prediction in Patients with Lower-Grade Gliomas
CONCLUSION: Adding diffusion- and perfusion-weighted MRI radiomics to clinical features improved survival prediction in lower-grade glioma.PMID:38653567 | PMC:PMC11045349 | DOI:10.3349/ymj.2023.0323 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Chae Jung Park Sooyon Kim Kyunghwa Han Sung Soo Ahn Dain Kim Yae Won Park Jong Hee Chang Se Hoon Kim Seung-Koo Lee Source Type: research
Evaluating the predictive value of a coagulation-related gene model in glioma
CONCLUSION: This study established the correlation between the coagulation-related gene model and glioma prognosis, providing deeper insight into the mechanism and treatment of glioma.PMID:38650572 | DOI:10.5137/1019-5149.JTN.45238-23.2 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Ming Cao Jie Chen Rong-Zeng Guo Source Type: research
Non-Detection of HCMV Total Genomic DNA in Human Glioma Cells Genome
CONCLUSION: We found that the genomic DNA of all the samples was negative for HCMV genomic DNA. Thus, HCMV could not be detected in human glioma tumors and we put forward that HCMV genomic DNA was not incorporated into the genomic DNA of glioma cells. Thus, total viral DNA is not involved in the pathogenesis of glioma; however, small viral particles or specific genes might be incorporated into the genomic DNA of glioma cells, leading to cancer development. This prompts further studies for verification.PMID:38650560 | DOI:10.5137/1019-5149.JTN.42717-22.1 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Dilek Gokturk Meryem Damla Ozdemir Dervis Mansuri Yilmaz Source Type: research
Diffusion- and Perfusion-Weighted MRI Radiomics for Survival Prediction in Patients with Lower-Grade Gliomas
CONCLUSION: Adding diffusion- and perfusion-weighted MRI radiomics to clinical features improved survival prediction in lower-grade glioma.PMID:38653567 | PMC:PMC11045349 | DOI:10.3349/ymj.2023.0323 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Chae Jung Park Sooyon Kim Kyunghwa Han Sung Soo Ahn Dain Kim Yae Won Park Jong Hee Chang Se Hoon Kim Seung-Koo Lee Source Type: research
Evaluating the predictive value of a coagulation-related gene model in glioma
CONCLUSION: This study established the correlation between the coagulation-related gene model and glioma prognosis, providing deeper insight into the mechanism and treatment of glioma.PMID:38650572 | DOI:10.5137/1019-5149.JTN.45238-23.2 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Ming Cao Jie Chen Rong-Zeng Guo Source Type: research
Non-Detection of HCMV Total Genomic DNA in Human Glioma Cells Genome
CONCLUSION: We found that the genomic DNA of all the samples was negative for HCMV genomic DNA. Thus, HCMV could not be detected in human glioma tumors and we put forward that HCMV genomic DNA was not incorporated into the genomic DNA of glioma cells. Thus, total viral DNA is not involved in the pathogenesis of glioma; however, small viral particles or specific genes might be incorporated into the genomic DNA of glioma cells, leading to cancer development. This prompts further studies for verification.PMID:38650560 | DOI:10.5137/1019-5149.JTN.42717-22.1 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Dilek Gokturk Meryem Damla Ozdemir Dervis Mansuri Yilmaz Source Type: research
Expression of STAT3 and hypoxia markers in long-term surviving malignant glioma patients
Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with comple... (Source: BMC Cancer)
Source: BMC Cancer - April 23, 2024 Category: Cancer & Oncology Authors: Katerina Dvorakova, Veronika Skarkova, Barbora Vitovcova, Jiri Soukup, Hana Vosmikova, Zuzana Pleskacova, Adam Skarka, Michael Christian Bartos, Petr Krupa, Petra Kasparova, Jiri Petera and Emil Rudolf Tags: Research Source Type: research
Suberanilohydroxamic acid (SAHA), a HDAC inhibitor, suppresses the effect of Treg cells by targeting the c-Myc/CCL1 pathway in glioma stem cells and improves PD-L1 blockade therapy
ConclusionSAHA inhibited the binding of c-Myc with the CCL1 promoter and then suppressed the transcription of CCL1.Additionally, it effectively blocked the interplay of CCL1-CCR8, resulting in reduced activity of Tregs and alleviation of tumor immunosuppression. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - April 23, 2024 Category: Cancer & Oncology Source Type: research
Mesenchymal stem cells as therapeutic vehicles for glioma
Cancer Gene Therapy, Published online: 23 April 2024; doi:10.1038/s41417-024-00775-7Mesenchymal stem cells as therapeutic vehicles for glioma (Source: Cancer Gene Therapy)
Source: Cancer Gene Therapy - April 23, 2024 Category: Cancer & Oncology Authors: Tomoya Oishi Shinichiro Koizumi Kazuhiko Kurozumi Source Type: research
Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives
AbstractPlant-derived immunomodulators and antitumor factors have appealed lots of attention from natural product scientists for their efficiency and safety and their important contribution to well-designed targeted drug action and delivery mechanisms. Zerumbone (ZER), the chief component ofZingiber zerumbet rhizomes, has been examined for its wide-spectrum in the treatment of multi-targeted diseases. The rhizomes have been used as food flavoring agents in numerous cuisines and in flora medication. Numerous in vivo and in vitro experiments have prepared confirmation of ZER as a potent immunomodulator as well as a potential...
Source: Medical Oncology - April 23, 2024 Category: Cancer & Oncology Source Type: research
