FDA and EMA Accept Vorasidenib Regulatory Submissions for the Treatment of IDH-mutant diffuse glioma
Boston, MA, Suresnes, France, February 20 2024– Servier, a global leader in oncology focused on delivering meaningful therapeutic progress for the patients it serves, today announced the FDA filing acceptance and priority review for a New... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - February 20, 2024 Category: Drugs & Pharmacology Source Type: news

AI spots unidentified brain tumor on PET imaging
An AI algorithm designed for brain PET imaging found a glioblastoma in a patient that had gone undetected by physicians, according to a case reported February 15 in the Journal of Nuclear Medicine.“This incidental finding highlights the potential of AI-based decision support for patient management in terms of diagnostic and treatment planning based on amino acid PET,” noted lead author Philipp Lohmann, PhD, of Aachen University in Aachen, and colleagues.In brief, the deep learning-based AI model (called “JuST_BrainPET”) is designed to automatically segment metabolic tumor volume (MTV) from surrounding healthy tissu...
Source: AuntMinnie.com Headlines - February 19, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Neuroradiology Source Type: news

Targeting IDH Mutated Glioma: A Decade ’s Journey from Bench to Bedside. Targeting IDH Mutated Glioma: A Decade ’s Journey from Bench to Bedside.
Prof Tim Cloughesy reviews the key early development milestones that lead to the evaluation of Vorasidenib in the INDIGO trial.Medscape Medical Affairs (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 8, 2024 Category: Consumer Health News Tags: None Virtual Symposium Source Type: news

Management of IDH-Mutated Gliomas in Germany Management of IDH-Mutated Gliomas in Germany
Learn how expert referral centres optimise treatment for their glioma patientsMedscape Medical Affairs (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 8, 2024 Category: Consumer Health News Tags: None Virtual Symposium Source Type: news

Navigating the Paradigm Shift: A New Era of Glioma Care. Navigating the Paradigm Shift: A New Era of Glioma Care.
Hear Prof Ghazaleh Tabatabai discuss how new clinical data and the application of ‘Personalised Treatment Strategies’ is impacting the care of glioma patients.Medscape Medical Affairs (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 8, 2024 Category: Consumer Health News Tags: None Virtual Symposium Source Type: news

NeuExcell's AAV Gene Therapy for Malignant Glioma Granted Orphan Drug Designation by FDA
PHILADELPHIA, Dec. 18, 2023 -- (Healthcare Sales & Marketing Network) -- On December 7, 2023, the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation ("ODD") to NXL-004, an investigational AAV gene therapy product being devel... Regenerative Medicine, Neurosurgery, Oncology, FDA NeuExcell Therapeutics, malignant glioma, gene therapy, glioblastoma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 18, 2023 Category: Pharmaceuticals Source Type: news

Hear firsthand how patients with IDH-mutated gliomas can receive personalised therapy Hear firsthand how patients with IDH-mutated gliomas can receive personalised therapy
A capsule of the progress in treating IDH mutant gliomasMedscape Medical Affairs (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 7, 2023 Category: Consumer Health News Tags: None Virtual Symposium Source Type: news

‘Tiny Pretty Things’ Actor Barton Cowperthwaite Diagnosed With Stage 2 Glioma; Plans To Undergo Brain Surgery To Remove Tumor
Barton Cowperthwaite, star of Netflix’s Tiny Pretty Things, is opening up about his health and revealed he was diagnosed with Stage 2 brain cancer. The actor in the streaming series said that he plans to undergo surgery to remove the brain tumor. “So…. Yesterday I was diagnosed with at least a…#bartoncowperthwaite #netflix #tinyprettythings #2glioma #cowperthwaite #docs #orenlennox #michaelmaclennan #sonacharaipotra #dhonielleclayton (Source: Reuters: Health)
Source: Reuters: Health - November 14, 2023 Category: Consumer Health News Source Type: news

Mapping cell behaviors in high-grade glioma to improve treatment
The researchers profiled 313 tumor biopsies from 68 high-grade glioma (HGG) patients. This image is a representation of the 3-dimensional relationship of multiple tissue biopsies from a single patient ’s HGG tumor. The different colors depict different versions of genetic mutations relative to the epidermal growth factor receptor gene. High-grade gliomas are cancerous tumors that spread quickly in the brain or spinal cord. In a new study led by Mayo Clinic, researchers found invasive brain tumo r… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 10, 2023 Category: Databases & Libraries Source Type: news

Day One Announces FDA Acceptance of NDA and Priority Review for Tovorafenib in Relapsed or Progressive Pediatric Low-Grade Glioma (pLGG)
BRISBANE, Calif., Oct. 30, 2023 (GLOBE NEWSWIRE) -- Day One Biopharmaceuticals (Nasdaq: DAWN) (“Day One” or the“Company”), a clinical-stage biopharmaceutical company dedicated to developing and commercializing targeted... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - October 30, 2023 Category: Drugs & Pharmacology Source Type: news

Imaging Biometrics touts IB Neuro study
Advanced visualization software firm Imaging Biometrics highlighted a study featuring its IB Neuro software for assessing brain tumors.IB Neuro performs quantitative analysis of MRI dynamic susceptibility contrast (DSC) studies, a common perfusion MRI exam for evaluating brain tumors, according to the vendor.In the study, published September 28 in Nature Communications, researchers at the Mayo Clinic in Arizona obtained multiple biopsies from different regions of tumors in patients with high-grade gliomas. They recorded the precise location of each biopsy using stereotactic coordinates.Then, each biopsy sample was matched ...
Source: AuntMinnie.com Headlines - October 18, 2023 Category: Radiology Authors: AuntMinnie.com staff writers Tags: Industry News Source Type: news

Attend the symposium virtually to hear the latest updates on adult diffuse IDH mutant gliomas. Attend the symposium virtually to hear the latest updates on adult diffuse IDH mutant gliomas.
Six expert faculty discuss various aspects of the evolving data for IDH mutation inhibition in patients with adult diffuse gliomas.Medscape Medical Affairs (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 9, 2023 Category: Consumer Health News Tags: None Virtual Symposium Source Type: news

Case of frontal glioma with a factitious disorder of self-inflicting dental injuries managed by coronally advanced flap with orthodontic buttons - Pattnaik A, Pattnaik N, Das M, Dash D.
Factitious disorders represent deliberately fabricated dissimulation of physical and psychological signs and symptoms seeking medical attention by the patient. Usually, they are ignorant of conventional treatment and consistently change their version of si... (Source: SafetyLit)
Source: SafetyLit - September 25, 2023 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Dabrafenib, Trametinib Active in Pediatric Glioma With BRAF V600
THURSDAY, Sept. 21, 2023 -- Dabrafenib plus trametinib results in significantly more responses and longer progression-free survival than standard chemotherapy for pediatric patients with low-grade glioma with BRAF V600 mutations, according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 21, 2023 Category: Pharmaceuticals Source Type: news

Epigenetic Marks May Cause Brain Tumor Formation
Scientists established an epigenetic mouse model for glioma, providing insight into how epigenetics can initiate cancer. (Source: The Scientist)
Source: The Scientist - September 19, 2023 Category: Science Tags: News News & Opinion Source Type: news