Fluorescence Can ID High - Grade Glioma During Sx for Brain Tumor
Visible fluorescence shows presence of high - grade glioma cells within tumor mass during surgery (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 6, 2018 Category: Cancer & Oncology Tags: Neurology, Oncology, Pathology, Radiology, Surgery, Conference News, Source Type: news
Fluorescence Can ID High-Grade Glioma During Sx for Brain Tumor
TUESDAY, Nov. 6, 2018 -- The presence of visible fluorescence can serve as an intraoperative diagnostic surgical biomarker of high-grade glioma within a brain tumor, according to a study presented at the 2018 National Cancer Research Institute... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 6, 2018 Category: Pharmaceuticals Source Type: news
Liquid Biopsy May Reveal Treatment Response in Pediatric Brain Tumors Liquid Biopsy May Reveal Treatment Response in Pediatric Brain Tumors
In children with diffuse midline glioma (DMG), liquid biopsy based on analyses of circulating tumor DNA (ctDNA) in cerebral spinal fluid (CSF) or plasma shows promise for detecting mutational load and may serve as tool for assessing tumor response to treatment, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - October 17, 2018 Category: Pathology Tags: Hematology-Oncology News Source Type: news
Human Brain Microvascular Endothelial Cell in Action
Recent PubsOur HumanBrain Microvascular Endothelial Cells (HBMECs) are known for the performance in drug discovery and tox assays. These 21-CFR compliant cells are used in the " blood side " of our3-D BBB Models.Shavali Shaik, Bridget Kennis, Shinji Maegawa, Keri Schadler, Yang Yanwen, Keri Callegari, Rishi R. Lulla, Stewart Goldman, Javad Nazarian, Veena Rajaram, Jason Fangusaro, and Vidya Gopalakrishnan. (2018).REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature. Oncotarget. 2018 Jan 12; 9(4): 5233 –5250. doi: 10.18632/oncotarget.23750 Hu et al. (2016). Epigenetic Activation of WNT5A ...
Source: Neuromics - September 20, 2018 Category: Neuroscience Tags: Blood Brain Barrier Blood Brain Barrier Models brain microvascular endothelial cells HBMECs human brain microvascular Source Type: news
Researchers to study brain cancer with Department of Defense funding
(Henry Ford Health System) Henry Ford Health System's Department of Neurosurgery was awarded a $600,000 grant by the Department of Defense to study the genetic makeup of gliomas, a type of brain cancer, in hope of identifying new therapies. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 18, 2018 Category: Cancer & Oncology Source Type: news
The boy whose clumsiness turned out to be cancer
Atticus Feduchin-Pate, from Whitchurch in Hampshire, has been diagnosed with a terminal high-grade cancer called diffuse intrinsic potine glioma which cannot be operated on. (Source: the Mail online | Health)
Source: the Mail online | Health - September 6, 2018 Category: Consumer Health News Source Type: news
Non-Hispanic White Patients Have Higher Glioma Incidence Non-Hispanic White Patients Have Higher Glioma Incidence
Dr Laurie Barclay comments on a study that aimed to quantify the differences in incidence and survival in adults with glioma by race or ethnicity.Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 23, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news
Georgetown releases cache of brain cancer data
Georgetown Lombardi Comprehensive Cancer Center has released a set of brain...Read more on AuntMinnie.comRelated Reading:
FLT-PET points toward survival for glioblastoma patients
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SNMMI: FDOPA-PET/MRI monitors pediatric brain tumors (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 15, 2018 Category: Radiology Source Type: news
Researchers use microparticles for targeted delivery of brain cancer therapy
Credit: Christine Daniloff/MIT
A team of researchers from Brigham & Women’s Hospital, Mass. Institute of Technology and Mass. General Hospital demonstrated that localizing the delivery of NAMPT inhibitors can extend survival in a mouse model of glioma, according to a paper published this week in the Proceedings of the National Academy of Sciences.
The scientists created a test to check for a mutation linked to glioma and implanted microparticles that slowly elute drug over the course of several days or even weeks to treat the brain cancer.
Get the full story at our sister site, Drug Delivery Business News.
The...
Source: Mass Device - August 7, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Oncology Pharmaceuticals Research & Development Brigham & Women's Hospital Massachusetts General Hospital Massachusetts Institute of Technology Source Type: news
A targeted approach to treating glioma
(Massachusetts Institute of Technology) Researchers from MIT, Brigham and Women's Hospital, and Massachusetts General Hospital have developed a new way to treat low-grade glioma. They devised a test that can rapidly check for the IDH mutation during brain surgery, and if the mutation is present, they can implant microparticles that gradually release an IDH-targeted drug over several days or weeks. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 6, 2018 Category: Biology Source Type: news
Rapid diagnostic coupled with local therapy developed for brain tumors
(Brigham and Women's Hospital) Working together, researchers from Brigham and Women's Hospital (BWH) and neurosurgeons from Massachusetts General Hospital (MGH), along with colleagues at MIT, are designing a new, rapid molecular diagnostic and sustained release therapeutic that could be deployed during brain surgery to treat gliomas and prevent their return. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 6, 2018 Category: Cancer & Oncology Source Type: news
Rapid Diagnostic Coupled with Local Therapy Developed for Brain Tumors
Interdisciplinary team develops rapid molecular diagnostic coupled to sustained release therapeutic to treat gliomas during surgery (Source: BWH News)
Source: BWH News - August 6, 2018 Category: Hospital Management Source Type: news
FLT-PET points toward survival for glioblastoma patients
PET scans with the radiotracer F-18 fluorothymidine (FLT) can help determine...Read more on AuntMinnie.comRelated Reading:
SNMMI: PET, MRI may predict pediatric brain tumor outcomes
FDG-PET/CT beats FLT-PET/CT for differentiated thyroid cancer
FLT-PET could help predict outcome in head and neck cancer
JNM: FLT-PET aids prognosis of glioma patients
FLT-PET helps predicts cancer therapy results (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 26, 2018 Category: Radiology Source Type: news
TGen opens DIPG tissue donation portal to accelerate research
(The Translational Genomics Research Institute) A tissue donation portal opened today at TGen, which will advance research towards new treatments for an aggressive brain cancer that mostly strikes young children. This new portal will accelerate the ability of families of children with DIPG -- or Diffuse Intrinsic Pontine Glioma -- to help TGen build a tissue bank that will aid researchers in their investigations of this rare and currently incurable disease that strikes about 350 children in the US each year. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 17, 2018 Category: Cancer & Oncology Source Type: news
