Neuromics Microglia in Action
Researchers Study Migration of Neuromics Microglia in Bio-ScaffoldsCheck out the publication-https://www.sciencedirect.com/science/article/pii/S2405844023005595.Images: Migration of MicrogliaHere ' s a link to Neuromics ' portfolio of cells for Neurocientists-https://www.neuromics.com/neurons-astrocytes-schwann-cells-microglia. (Source: Neuromics)
Source: Neuromics - March 2, 2023 Category: Neuroscience Tags: 3-D Blood-Brain Barrier Model Glia neuroscience Source Type: news
Neuromics' Astrocytes/Pericytes used to Form Organoid BBB Model
BBB Model Used to Study How Lyme neuroborreliosis (LNB) penetrates the Brian.Yvonne Adams, Anne Skovsbo Clausen, Peter Østrup Jensen, Malin Lager, Peter Wilhelmsson, Anna J. Henningson, Per-Eric Lindgren, Daniel Faurholt-Jepsen, Helene Mens, Peter Kraiczy, Kasper Nørskov Kragh, Thomas Bjarnsholt, Andreas Kjaer, Anne-Mette Lebech, Anja R. Jensen,3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism, iScience, Volume 26, Issue 1, 2023, 105838, ISSN 2589-0042, https://doi.org/10.1016/j.isci.2022.105838.Image: LNB Penetrating the BBB (green Fluorescence)Re...
Source: Neuromics - January 29, 2023 Category: Neuroscience Tags: Astrocytes Blood Brain Barrier Human Pericytes Lymes Disease Source Type: news
Neuromics' Microvascular Endothelial Cells in Action
Widely Used and Data RichNeuromics HumanBrain Microvascular Endothelial Cells (HBMECS) are frequently used and data rich. Here are HBMECS in culture showing early microtubular formation.HBMECS in culture showing early microtubular formationThey are an excellent component for building Blood-Brain Barrier (BBB) Models. Questions? E-mail Mr. David Rupp-david@neuromics.com. (Source: Neuromics)
Source: Neuromics - November 17, 2022 Category: Neuroscience Source Type: news
Cancer Associated Fibroblasts and Cell Lines
Wide VarietyNeuromics has a growing catalog ofCAFS and Cell Lines. Here ' s an example of ourBreast CAFS.Breast CAFs in culture. Grown using Stem Cell Complete Low Serum Media (cat. CAFM02)Cells are prepared and manufactured in anISO 9001:2015 certified environment and ISO 5 cleanroom.Questions? email david@neuromics.com (Source: Neuromics)
Source: Neuromics - October 13, 2022 Category: Neuroscience Source Type: news
Neuromics' Human Neurons in Action
Our primary human neurons (cat. HNC001) have been busy lately, continuing to become one of our most popular and versatile products. Earlier this month, Japanese researchers published their findings when creating 3D brain-like spheroids containing our primary human neurons. Their results suggest the spheroids mimic in vivo conditions and are suitable for use as an in vitro neurological disease model. Check out the publication for yourself here.Human Neurons in CultureSince the beginning of 2022, our neurons have been cited a number of times spanning various research are...
Source: Neuromics - July 29, 2022 Category: Neuroscience Source Type: news
Potent and Pure Fetal Bovine Serum
Potent and pure FBS. Single use, triple filtered and manufactured under the strictest guidelines, Pricing starts at $245/500 mlCheck us out Fetal Bovine Serum. (Source: Neuromics)
Source: Neuromics - April 20, 2022 Category: Neuroscience Source Type: news
Introducing our Prostate Cancer Cells Lines
Check out the OptionsNeuromics is pleased to introduce many of the top human prostate cancer cell lines to our already expansive selection of cell offerings. To complement the DU 145 cells we added earlier this year, Neuromics is now offering VcaP, LNCaP, and PC-3 cells to complete our catalog of human prostate cancer cell lines.Image: VcaP cells in culture.VCaP cells are known for their high androgen receptor and PSA expression. Unlike most other prostate cancer cell lines,LNCaP cells are highly sensitive to androgens and have a low tumorigenicity. Meanwhile,PC-3 cells are noted for their high metastatic potential a...
Source: Neuromics - February 15, 2022 Category: Neuroscience Tags: cancer prostate cancer Tumor tumor cells Source Type: news
Neuromics' Human Brian Microvascular Endothelial Cells in Action
Fc-saxatilin inhibits VEGF-induced permeability by regulating claudin-5 expression in human brain microvascular endothelial cells (HBMVECs)Neuromics ' cells were at the heart of this study.Highlights: Fc-saxatilin prevents VEGF-induced permeability in human brain microvascular cells (HBMVECs). Fc-saxatilin inhibits VEGF-induced Src and Fak phosphorylation in HBMVECs. Fc-saxatilin blocks the downregulation of claudin-5 expression by VEGF in HBMVECs.Image: HMBECS in CultureProtocol: Human brain microvascular endothelial cells (HBMVECs) were purchased from Neuromics (HEC02; Minneapolis, MN, USA). HBMVECs were m...
Source: Neuromics - January 25, 2022 Category: Neuroscience Tags: human brain microvascular cells Human microvascular endothelial cells Source Type: news
TRPV1 and Migraines
Conclusion-the present findings indicate that insulin may activate TRPV1 receptors in the trigeminovascular system. Modified TRPV1 receptor function induced by insulin may also increase the sensitivity of both neural and vascular TRPV1 receptor for its agonists. Our data may provide a pathophysiological basis for the increased incidence of migraine in patients with hyperinsulin levels. (Source: Neuromics)
Source: Neuromics - January 21, 2022 Category: Neuroscience Source Type: news
About IBA Lifesciences
IBA Lifesciences ' proprietary Strep-tag ® technology exploits one of the strongest non-covalent interactions in nature: the interaction of biotin and streptavidin. The system is based on the highly selective and easily controllable interaction between the synthetic Strep-tag®II peptide and the specially engineered streptavidin, called S trep-Tactin®, which is one of the most stable proteins known. The Strep-tag®II binds specifically to the engineered streptavidins, Strep-Tactin® and Strep-Tactin®XT, by occupying the binding pocket of the natural ligand biotin. Hence, the interaction is easily reversible by excessive...
Source: Neuromics - December 31, 2021 Category: Neuroscience Source Type: news
Studying Diabetic Retinopathy?
Check out How Neuromic ' s Tools Are UsedThe authors used four of Neuromics to complete this study-Sulodexide reduces glucose induced senescence in human retinal endothelial cellsA. Gericke, K. Suminska-Jasi ńska& A. Br ęborowicz Scientific Reports volume 11, Article number: 11532 (2021) Cite this article.Material and MethodsExperiments were performed on HREC (#HEC09, Neuromics, Edina, MN, USA) in in vitro culture. Cells were seeded in 75 cm2 culture flasks coated with AlphaBioCoat Solution (#AC00, Neuromics, Edina, MN, USA) and were grown in Endo Growth Medium (EKG001, Neuromics, Edina, MN, USA) supplemented with fe...
Source: Neuromics - November 24, 2021 Category: Neuroscience Tags: Cell Detachment Diabetic retinopathy Human Endothelial Cells Human Retinal Microvascular Endothelial Cells Hyperglycemia Source Type: news
Neuromics' FBS and National Cancer Institutes
Best Price and Performance I was honored to work with Jessey at National Cancer Institute (NCI).The were determining whether to change partners. According to Jessey, there were 24 lab PIs who would be supplied with the winner ' s FBS Although we proved competitive, we were not selected.The study was uconducted with only premium grade FBS (most expensive). We are announcing a new Preferred FBS this Monday 10/25. It works well for supplementing define media and works great for most human primary sells. And works fabulous for human and animal cancer cells.Interested in learning more? Contact me at pshuster@neuromic...
Source: Neuromics - October 23, 2021 Category: Neuroscience Tags: Bone Cancer Pain Cancer Associated Fibroblasts cell biology FBS Fetal Bovine Serum national cancer Institute Source Type: news
Neuromics-3D Human Blood Brain Barrier!
Compound Penetration Study Classification: Low permeability: Pe< 1.00 nm/s Moderate permeability: 1.00< Pe< 10.0 nm/s High permeability: Pe> 10.0 nm/s * The signal responses of Atenolol , Sulpiride, and Cimetidine in receiver samples were undetectable.For the convenience of calculation, 1/300 of the measured peak area ratio (PAR) of the relevant AD (A>B Donor) samples were used as the PAR values of Atenolol , Sulpiride, and Cimetidine in receiver samples.Check out the study-https://www.neuromics.com/ittrium/reference/D8xf65cx8x1/BBB%20Penetration%20Data.pdf ...
Source: Neuromics - October 6, 2021 Category: Neuroscience Source Type: news
Neuromics' Renal Proximal Tubule Cells in Action
In this study, ourRPT Cells were used to study the impact of Klothko expression on protection of kidneys in diabetics: Meng Xue, Feng Yang, Ying Le, Yanlin Yang, Bingsen Wang, Yijie Jia, Zongji Zheng, and Yaoming Xue. (2021).Klotho Protects Against Diabetic Kidney Disease via AMPK- and ERK-Mediated Autophagy. Acta Diabetologica, 32. doi: 10.1007/s00592-021-01736-4.Klotho expression in human renal proximal tubule cells after high-glucose stimulation. (a) Levels of Klotho mRNA and (b) Klotho protein were assessed in human renal proximal tubule cells treated with low glucose and high glu- cose. (c) Morphological observat...
Source: Neuromics - June 3, 2021 Category: Neuroscience Source Type: news
Trigeminal Neuralgia (Facial Pain)
Markers for Pain ResearchTrigeminal Neuralgia is a progress chronic condition. Dysfunctional trigeminal signaling can lead to intense, searing facial pain. It is caused by pressure on the trigeminal nerve.The root causes of the condition are not well understood. Ourpain research markers have been widely used and frequently published through the years and have been important contributors to our growth, Here ' s a recent pub referencing use of one ourP2X3 Antibodies-Momoko Koizumi, Sayaka Asano, Akihiko Furukawa, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Katsuhiko Hayashi, Fusao Kato, Koichi Iwata, and Masamichi...
Source: Neuromics - May 27, 2021 Category: Neuroscience Tags: Craniofacial pain P2X3 Antibody P2X3 Receptor Antibody Trigeminal Neurons Source Type: news
