Trigeminal Neuralgia (Facial Pain)
Markers for Pain ResearchTrigeminal Neuralgia is a progress chronic condition. Dysfunctional trigeminal signaling can lead to intense, searing facial pain. It is caused by pressure on the trigeminal nerve.The root causes of the condition are not well understood. Ourpain research markers have been widely used and frequently published through the years and have been important contributors to our growth, Here's a recent pub referencing use of one ourP2X3 Antibodies-Momoko Koizumi, Sayaka Asano, Akihiko Furukawa, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Katsuhiko Hayashi, Fusao Kato, Koichi Iwata, and Masamichi S...
Source: Neuromics - May 27, 2021 Category: Neuroscience Tags: Craniofacial pain P2X3 Antibody P2X3 Receptor Antibody Trigeminal Neurons Source Type: news
Malaria and the Blood-Brain Barrier
EPCR and ICAM ReceptorsNeuromicsAstrocytes and Pericytes were used in this important study-Yvonne Adams, Rebecca W. Olsen, Anja Bengtsson, Nanna Dalgaard, Mykola Zdioruk, Sanghamitra Satpathi, Prativa K. Behera, Praveen K. Sahu, Sean E. Lawler, Klaus Qvortrup, Samuel C. Wassmer, and Anja T.R. Jensen. (2021).Plasmodium Falciparum Erythrocyte Membrane Protein 1 Variants Induce Cell Swelling and Disrupt the Blood –Brain Barrier in Cerebral Malaria. Journal of Experimental Medicine, 218 (3). doi: 10.1084/jem.20201266.This is the first study showing malaria pericytes interacting with human endothelial cells. Please ...
Source: Neuromics - February 1, 2021 Category: Neuroscience Tags: 3-D Blood-Brain Barrier Model –brain barrier penetration brain microvascular endothelial cells human Astrocytes Human Endothelial Cells Human Pericytes Source Type: news
Human Schwann Cells that Work
No Doubt!Sometimes we hear our human cells did not express a certain receptor in the hands of our customers. We guarantee our cell " walk and talk " as advertised. If you are ever in doubt. we will test for expression of any receptors or cytoplasmic proteins. We also do this as part of our quality checks.Here're, for example, is a pub showing our Schwann Cells working. Note the receptors tested here. Seung Min Shin, Francie Moehring, Brandon Itson-Zoske, Fan Fan, Cheryl L. Stucky, Quinn H. Hogan, and Hongwei Yu. (2021). Piezo2 Mechanosensitive Ion Channel is Located to Sensory Neurons and Non-Neuronal Cells...
Source: Neuromics - January 26, 2021 Category: Neuroscience Tags: chronic pain human primary primary human cells Schwann Cell Markers Schwann Cells Source Type: news
Cancer Associated Fibroblasts (CAFS) Traction Dynamics and Remodeling in 3D Matrices
Neuromics'Colorectal CAFS in ActionIn a first of its kind study, the mechanical properties of ourCAFS were determined. This is important because, understanding how these cell behavein vivowill help improve the efficacy of new therapies: Bashar Emon, Zhengwei Li, Md Saddam Hossain Joy, Umnia Doha, Farhad Kosari, and M Taher A Saif. (2020).A Novel Method for Sensor-Based Quantification of Single/Multi-Cellular Traction Dynamics and Remodeling in 3D Matrices. bioRxiv. doi: 10.1101/2020.09.24.311647" Cells in vivo generate mechanical forces (traction) on surrounding 3D extra cellular matrix (ECM) and cells. Such tra...
Source: Neuromics - November 25, 2020 Category: Neuroscience Tags: 3-D Assays. 3-D imaging CAFs Cancer Associated Fibroblasts colorectal CAFs Colorectal Cancer Source Type: news
Neuromics' n-Fect Delivers
Gene Expression Tools in ActionNeuromics has a wide offering of transfection reagents that are perfect for both in vivo and in vitro applications. We take pride in seeing our product used in research, which is certainly true of our transfection reagents (see here).Furthermore, we'd like to highlight a recent use of our n-Fect Transfection Kit (cat.# NF30150) in a doctoral thesis recently published. The paper looked into the neuroscience of alcohol addiction, looking towards the purinergic family receptor P2X4, which has been linked to alcohol addiction in mouse m...
Source: Neuromics - October 23, 2020 Category: Neuroscience Tags: gene expression analysis p-Fect Transfection Source Type: news
Premium Virus Transport Media vs PBS
There is a differenceHere's a video that illustrates the difference between CDC recommended Virus Transport Media and Sterile PBS (salt water). It answers the questions " what is in your VTM " and " why does it matter " . Please consider sharing so it can find its way to those in need!Check out our VTM-https://www.neuromics.com/virus-transport-media (Source: Neuromics)
Source: Neuromics - September 19, 2020 Category: Neuroscience Tags: COVID-19 Test Kits COVID-19 Transport Media PBS Phosphate Buffered Saline Virus Transport Media Source Type: news
Method of treating central nervous system disease
Blood-Brain Barrier (BBB) Permeability AssayYes, These are troubled times. With our current focus on eradicating COVID-19, we forget that many of the world's most insidious and costly diseases have limited treatments and no cures.That is why Neuromics continues to develop its human based 3-D Cell-Based Assays. At the center if our offerings is ourBBB Model.Here's a recent patent application that includes a permeability assay using our model-Sookhee Bang, Jeong Kuen Song, Seung-wook Shin, Kwan Hee Lee, and Ho June Lee. (2020).Method of Treating Central Nervous System Disease. United States Patent Application 202002302...
Source: Neuromics - August 20, 2020 Category: Neuroscience Tags: 3-D Assays. 3-D imaging 3-D Blood-Brain Barrier Model 3-D Cell Culturing Blood Brain Barrier Blood Brain Barrier Models –brain barrier penetration Source Type: news
We Have FBS in Bulk Available
Key Component of Virus Transport Media (VTM)Neuromics is known to have some of the bestFetal Bovine Serum (FBS)for most applications. This includes being a component ofVTM manufactured to the CDC's most recommended recipe.Unlike some other suppliers, we are fully transparent as to pricing and available inventory. Check us out today. (Source: Neuromics)
Source: Neuromics - July 27, 2020 Category: Neuroscience Tags: FBS Fetal Bovine Serum Virus Transport Media VTM Source Type: news
We Have VTM in Bulk
At Capacity for VTM Based COVID-19 Sample Transport KitsWe are well on our way to delivering 100,000 Tubes + VTM to the state of Ohio. A big thank you to my team and friends for making this happen.5,000 Tubes+VTM Ready to Ship to OhioWe do have a capacity to provide 4,000 Liters/Week ofVTM in 1 Liter Bottles.If you have current or future needs do not hesitate to contact me directly @ email@example.com or direct phone 612-801-1007. Pete Shuster, Owner, Neuromics (Source: Neuromics)
Source: Neuromics - June 25, 2020 Category: Neuroscience Tags: COVID-19 Storage Media COVID-19 Test Kits COVID-19 Transport Media Virus Transport Media VTM Source Type: news
We Have VTM and COVID19 Test Kits
Providing Kits Coast to Coast and Points in BetweenFrom Seattle, Washington to New York City and in between, ourVirus Transport Medium has been used in COVID-19 testing. Neuromics is doing our part by helping to expand testing capacity, allowing the nation to recover from the harships associated with the pandemic.Our VTM is manufactured using ourFBS following CDC guidelines, ensuring that it is sterile and safe for testing. Additionally, each lost of VTM goes through quality control before release (sample CoA). We offer our VTM in many different forms, including kits (tubes and sterile swabs) and larger quantities tha...
Source: Neuromics - May 16, 2020 Category: Neuroscience Tags: COVID-19 Storage Media COVID-19 Test Kits FBS Fetal Bovine Serum Source Type: news
We Have Virus Transport Media (VTM) in Tubes
VTM The Way You Need ItWe have Virus Transport Media in tubes with 2 options.SizePriceVTM-1: 2 ml 15 ml tube (100 mm) - qty 15 (Available after 4/24)$69.00VTM-2: 2 ml 15 ml tube (120 mm) - qty 15$74.00We can also provide tubes with custom volumes of VTM.Should you have questions or want to explore custom VTM volume options, please contact me directly at firstname.lastname@example.org.Pete ShusterCEO and OwnerNeuromics (Source: Neuromics)
Source: Neuromics - April 15, 2020 Category: Neuroscience Tags: Coronavirus COVID-19 Storage Media COVID19 Viral Storage Media Viral Transport Media Virus Storage Media Virus Transport Media Source Type: news
Schwann Cell Data
Quality CountsThough rare, we occasionally have clients challenge the phenotype of our 21-CFR complianthuman primary cells. This challenge is usually a result of certain markers not being expressed when they run immuno-fluorescence assays.When this happens, we too test the cells in question using the antibodies against the markers in question. We have a world class team doing immuno-fluorescence assays.Recently a customer claimed ourschwann cells were negative for GFAP and P0. Here're our testing results.For P0 (CH23009) we used green fluorescence +DAPI.For GFAP (RA22101) we used red fluorescence + DAPI (blue) counte...
Source: Neuromics - April 8, 2020 Category: Neuroscience Tags: GFAP Antibody Glia Markers Glial Fibrillary Acidic Protein Antibody human primary schwann cells P0 antibody PZero Antibody Schwann Cell Markers Source Type: news
We have Corona Virus Transport Media
! We are pleased to announce we now have media designed to move COVID-19 testing samples from point A to B. It's pricing is in line with all the many media we currently provide. If you know of any hospitals, clinics or testing facilities that would benefit we all are ears-https://www.neuromics.com/VTM #covid19 #coronavirus (Source: Neuromics)
Source: Neuromics - March 26, 2020 Category: Neuroscience Tags: Coronavirus COVID19 Source Type: news
We Are Open
Providing Cells, Media and Supplements in the time of Covid-19If you call us, we will answer the phone. If you submit an order, it will ship.Neuromics stands ready to serve you.Image: Neuromic's Human Pancreatic CAF-Stellate Cells in CultureFBS only $299/500 ml. We have plenty of inventory so we can continue with this pricing for the duration of the Pandemic.Stay safe. (Source: Neuromics)
Source: Neuromics - March 17, 2020 Category: Neuroscience Tags: Cancer Associated Fibroblasts FBS Fetal Bovine Serum human cancer cells Human Endothelial Cells primary human cells Source Type: news
Save Hundreds on Tet Free FBS
For Healthy and Happy CulturesCheck it out. Only $299/500 ml.USDA Origin FBS.Single use automated processing system from filtering to labeling.Questions? Contact me directly @email@example.com.Pete Shuster-CEO and Owner (Source: Neuromics)
Source: Neuromics - February 24, 2020 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news
Customer Data Wanted
Reward is a $25 Amazon Gift CardWe are always honored when you share yourdata with us! To learn more check out the video.We make it easy to share. Just email your data to firstname.lastname@example.org. We will email you the gift card. (Source: Neuromics)
Source: Neuromics - February 10, 2020 Category: Neuroscience Tags: 3-D Cell based Assays endothelial cells FBS Glia human Astrocytes Human Neurons human primary schwann cells Source Type: news
Our New USDA FBS is Tet Free
Compare and Save!In researching Neuromics'Competitors pricing on Tetracycline Free FBS, I noticed pricing ranging from $650-1,000+. Check us out. Only $299/500 ml. bottle.FBS - Fetal Bovine Serum USDA OriginFBS002500 mL$299.00Here's our COA.To learn more simply email@example.com. (Source: Neuromics)
Source: Neuromics - February 5, 2020 Category: Neuroscience Tags: FBS Fetal Bovine Serum Tet free Tetracycline free Source Type: news
Fetal Bovine Serum-More Data
Primary and Stem Cell CultureThis just came across our radar." SUPPLEMENTARY MATERIAL An eye opener in stroke: Mitochondrial dysfunction and stem cell repair in MCAO induced retinal ischemia "We are always delighted when researchers supplement their cell culture media with ourFetal Bovine Serum (FBS).RPE Cells and MSC Culture Retinal pigmented epithelium (RPE, CRL-4000; ATCC) cells were cultured in Dulbecco ’s Modified Eagle Media/F-12 (DMEM/F-12, 11320033; Gibco) containing 10% fetal bovine serum (FBS; FBS001; Neuromics) and 0.01 mg/ml hygromycin B (10687010; Gibco) in incubator (37 °C humidified, with...
Source: Neuromics - January 17, 2020 Category: Neuroscience Tags: adult stem cells FBS Fetal Bovine Serum Human Mesenchymal Stem Cells MSCs Retinal Pigment Epithelial Cells RPES Source Type: news
Human Cancer Associated Fibroblasts
Customer Generated DataOur Cancer AssociatedFibroblasts (CAFs) are widely used and frequentlypublished.We always welcome customer data. We are especially pleased when the data confirms our cells are " walking and talking " as advertised. Here's a recent example," Biomarkers expression by flow and confocal microscopy using your CAFs. As flow cytometry indicated,>92% cells were live and we showed expected signals (Cy3) from the live cells. Nuclear dye is Hoechst showed as blue. " Courtesy of Jiehua Zhou, City of Hope.We offer a wide range ofhuman primary cells. Check them out today. (Source: Neuromics)
Source: Neuromics - January 11, 2020 Category: Neuroscience Tags: CAFs Cancer Associated Fibroblasts cancer cell cultures Cancer Research Source Type: news
Neuromics Teams with Biowest USA
Pure and Potent Chicken SerumWe have a new partnership with the source for much of the Animal Sera provided worldwide today. They are recognized as being one of the best of the best.I am proud to announce the addition of theirChicken Serum. Their processing is both ISO and GMP certified. Better yet, we have an introductory pricing of $99/500 ml. for the month of January.Chicken Primordial Germ Cells Cultured in Media Supplemented with Neuromics/Biowest USA's Chicken Serum.We will be greatly enhancing our Sera offerings in 2020. Stay tuned. (Source: Neuromics)
Source: Neuromics - January 7, 2020 Category: Neuroscience Tags: Animal Serum Chicken Serum FBA Source Type: news
Neuromics Teams with Biowest USA
Quality tested for the most sensitive cells and applicationsGreat new serum products for 2020. Check out our intro video.Happy Holidays. (Source: Neuromics)
Source: Neuromics - December 23, 2019 Category: Neuroscience Tags: BiowestUSA FBS Fetal Bovine Serum Source Type: news
Neuromics New FBS-329/500 ml.
Premium Ultra-pure FBS!Check it out todayUltrapure FBS is manufactured, by our OEM partner Biowest USA. in a fully integrated environment from raw material collection to finished product. Our production facility is fully certified to ISO 9000 and ISO 13485. Ultrapure means:Lowest endotoxin level 0,1 EU/mL. Triple 0,1 μm Filtered. Free of Virus and Mycoplasma. Tested Ideal for Sensitive Cells and Applications. This FBS can be used to culture all cell types including macrophages, cancer and cancer related cells, hybridomas and more. It works great for all ourhuman primary cells andstem cells. (Source: Neuromics)
Source: Neuromics - December 16, 2019 Category: Neuroscience Tags: adult stem cells CAFs Cancer Associated Fibroblasts Cancer Stem Cells endothelial cells FBS Fetal Bovine Serum Source Type: news
Great for use a controls vs Differentiated iPSCsWe have a cornucopia ofHuman Primary Neuron, Astrocytes and Schwann Cells plus CAFS. Featured Assays:Human Brain Pericytes used to study Guide Axon Guidance.Human Pancreatic CAFS and Tumor Dynamics.Axon guidance at the site of a cervical spinal cord injury in a rat model. (Ai) Schematic illustrating transplantation of scaffold into a C-4 hemisection. The injury cavity is shown prior to (ii) and immediately following (iii) transplantation. (Bi) Scaffold conditioned with flow exhibits viable GFP-labeled microvessels (green) (ii) and alignment of host axons (magenta) infiltratin...
Source: Neuromics - December 3, 2019 Category: Neuroscience Tags: adult stem cells CAFs Cancer Associated Fibroblasts human Astrocytes Human Endothelial Cells Human Neurons Primary Human Neurons Source Type: news
Optimizing Human Microglia Cultures
Healthy and Happy CellsMicroglia, one of the glial cell types in the CNS, is an important integral component of neuroglia cell network. They act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged.This makes them an important tool for drug discovery.We have research provenHuman Microglia.Neuromic's Microglia Cultured in T25 FlaskRelated Protocol:Place the flask in a clean Biosafety cabinet. Remove the seal on the T-25 Flask. Remove about 15-20ml of media from the flask. Change the cap on the flask, make sure media is not touching the...
Source: Neuromics - November 22, 2019 Category: Neuroscience Tags: Cell based assays Cell Cultures Human Microglia Source Type: news
Human Brain Microvascular Endothelial Cells and BBB
Fc-saxatilin used to Modulate Blood-Brain Barrier (BBB)Highlights•Fc-saxatilin prevents VEGF-induced permeability inNeuromics'human brain microvascular cells (HBMECs). •Fc-saxatilin inhibits VEGF-induced Src and Fak phosphorylation in HBMECs. •Fc-saxatilin blocks the downregulation of claudin-5 expression by VEGF in HBMECS.Hyun-Jung Choi, Na-Eun Kim, Il Kwon, Dukhwan Choi, Jayoung Kim, Ji Hoe Heo. (2019).Fc-saxatilin inhibits VEGF-induced permeability by regulating claudin-5 expression in human brain microvascular endothelial cells. Microvascular Research. DOI: https://doi.org/10.1016/j.mvr.2019....
Source: Neuromics - November 12, 2019 Category: Neuroscience Tags: 3-D Blood-Brain Barrier Model Blood Brain Barrier HBMECs human brain microvascular endothelial cells VEGF Source Type: news
Building InventoryThe supply ofFetal Bovine Serumcontinues to tighten. We are now on the brighter side of this after obtaining a healthy supply.The good news is we are able to hold our pricing at $379/500 ml.Our clients are finding it works for many different types of cells.Check out data. We are confident you will be delighted with results. (Source: Neuromics)
Source: Neuromics - October 25, 2019 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news
Taste and AgRP
How Hunger Impacts TasteNature Communications just released a publication featuring use of our Agouti-Related Protein (AgRP) Antibody.It examines the neuronal mechanisms regulating hunger-induced taste modification. Starved mice exhibit an increased preference for sweetness and tolerance for aversive taste. This hunger-induced taste modification is recapitulated by selective activation of orexigenic Agouti-related peptide (AgRP)-expressing neurons in the hypothalamus projecting to the lateral hypothalamus.Ou Fu, Yuu Iwai, Masataka Narukawa, Ayako W. Ishikawa, Kentaro K. Ishii, Ken Murata, Yumiko Yoshimura, Kazushige Touhar...
Source: Neuromics - October 15, 2019 Category: Neuroscience Tags: Agouti-Related Protein Antibody AgRP Antibody Neuronal Markers Source Type: news
Primary Human Cells Data
Internal TestingWe aredata hounds. This is especially true when customers generate results that conflict with ours. For example, if ourHuman Primary Cells, in the hands of our customers, stain negative for key markers, we always retest using a 3rd Party Lab. Here're recent results for ourHuman Schwann Cells.Neuromics'Schwann Cells stained with O1 Antibody (red) and DAPI (blue). Neuromics'Schwann Cells stained with s100 antibody (red) and DAPI (blue).It is imperative that all our cells work as advertised. If your results do not meet expectations, we will run similar tests to make sure they walk and talk as they should. (Source: Neuromics)
Source: Neuromics - October 2, 2019 Category: Neuroscience Tags: CD Markers human primary schwann cells S100B Antibody Schwann Cell Markers Source Type: news
High Fat and Diet Induced Obesity
i-FectTM Delivers Again!Research shows that rats and humans on a high-fat diet (HFD) are less sensitive to satiety signals known to act via vagal afferent pathways. Impaired vagal afferent responsiveness to both gastric satiety hormones (CCK and leptin) and mechanical stimulation raises the possibility that changes in electrophysiological properties may be the underlying mechanism responsible for impaired vagal responsiveness to a wide variety of satiety signals.Potassium channels play a central role. To demonstrate this researchers used ouri-Fect siRNA Transfection Kit to silence TRESK and TASK1 to understand there impact...
Source: Neuromics - September 16, 2019 Category: Neuroscience Tags: diabetes iFect obesity Obesity Research RNAi siRNA siRNA delivery in-vivo Source Type: news
Potent FBS-Only $289/500 ml.
Hurry!We our a bit over stocked inFBS. In order to fix, we are offering it for $289/500 ml. This offer is only good through September 15, 2019 so you will need to hurry.Primary mouse vascular smooth muscle cells stained with smooth muscle alpha actin in DMEM with Neuromics 10% FBS. Data courtesy of Deng-Fu Guo, University of Iowa.Note: We test each lot of FBS on our primary human cell cultures enabling us to choose lots yielding the best results...Testimonial: " We have used the FBS from Neuromics in feeding media for primary mouse astrocytes as well as for some cell lines. Your product is good and we plan to continue...
Source: Neuromics - September 7, 2019 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news
Human Primary Endothelial Cells
Potent, Pure and Culture ReadyLooking for endothelial cells? Check out relatedpublications andreviews.Ravi D. onBirdEye★★★★★4 months ago We have orderedBrain derived Endothelial Cells or BECs. We could not find these in different companies, particularly from multiple donors. Overall, we are happy with the products.Image: Human microvascular network formation based on microfluidic 3D HUVEC culture. a Schematic diagram of HUVECs seeding in the fibrin hydrogel. b Schematic diagram of microvascular network formation in the fibrin hydrogel. c Microscope image of HUVECs just seeding in fibrin hydrogel. d Confocal micro...
Source: Neuromics - August 28, 2019 Category: Neuroscience Tags: Endothelial Cell Proliferation endothelial cells human brain microvascular endothelial cells human umbilical cord endothelial cells Source Type: news
Only $339 USD/500 ml.We are pleased with the increasing amount of Data,Pubs andReviews. Here's some samples:DRGs cultured in media supplemented with Neuromics 'FBSGabriela Fernandes, Stephen T Vanyo, Shahad Bakheet Alsharif, Sebastiano Andreana, Michelle B Visser, Rosemary Dziak, Ph.D.Strontium Effects on Human Gingival Fibroblasts. https://doi.org/10.1563/aaid-joi-D-18-00253." I looked around for a good price on FBS and Neuromics has the best price and great selection. " Tracy Doebler - Aug 08, 2019 - Rating: 5.0You can request a sample by emailing Rose Ludescher, Manager, Customer Satisfactionrose@neu...
Source: Neuromics - August 17, 2019 Category: Neuroscience Tags: Dorsal Root Ganglia drgs FBS Fetal Bovine Serum Source Type: news
i-Fect Delivers circRNA and miRNA
Blocks Bone Cancer PainAltered expression of circular RNA (circRNA) is recognized as a contributor to malignant pain where microRNA (miRNA) exerts an essential effect. Researchers used ouri-FectTMTransfection Kit to knock them down. Zhongqi Zhang, Xiaoxia Zhang, Yanjing Zhang, Jiyuan Li, Zumin Xing. Yiwen Zhang.Spinal circRNA-9119 Suppresses Nociception by Mediating the miR-26a-TLR3 Axis in a Bone Cancer Pain Mouse Model. Spinal circRNA-9119 Suppresses Nociception by Mediating the miR-26a-TLR3 Axis in a Bone Cancer Pain Mouse Model. Journal of Molecular Neuroscience. pp 1 –10Intrathecal Administration of miRNA and ci...
Source: Neuromics - August 4, 2019 Category: Neuroscience Tags: Bone Cancer Pain circRNA iFect miRNA Transfection Transfection Reagents Source Type: news
Visikol HISTO Immunolabeling Tutorial
Great Technology from our PartnerCheck it out! (Source: Neuromics)
Source: Neuromics - July 22, 2019 Category: Neuroscience Tags: Immunofluorescence Immunohistochemistry Immunolabeling Source Type: news
Rodent Cortical Astroglia
In this study. the authors use our rat atsroglia as controls to determine homogeneity of iPSC derived cells.P. Ni, H. Noh, Z. Shao, Q. Zhu, Y. Guan, J.J. Park, F. Arif, J.M. Park, C. Abani, C. Beaudreault, J.S. Park, E. Berry, A. Moghadam, P. Stanton, J.N. Hutchinson, B. Andrews, C. Faux, J. Parnevelas, L.M. Eisenberg, K. Park, V.Y. Bolshakov, S. Chung. (2019).Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells. Molecular Therapy-Methods& Clinical Development, 13:414-430. doi: 10.1016/j.omtm.2019.04.002.Figure: CDP Treatment Enhance...
Source: Neuromics - July 11, 2019 Category: Neuroscience Tags: astrocyte cultures Astrocyte-Glial-Neuron Co-cultures induced pluripotent stem (iPS) cells iPSCs Source Type: news
Potent and Proven TUJ-1 Markers
Referenced in Over 50 PublicationsTuj-1 is a key marker for neurogenesis. It can be detected in immature neurons and persists throughout the adulthood. We have 2 options both are widely used and frequently published.Tuj-1 Chicken PolyclonalTuj-1 Mouse MonoclonalFigure: A-B Representative confocal images of tdTomato+/Myosin7a+ hair cells (asterisks and dashed lines) from early and late tracing associated with Tuj1+ neurites (arrowheads in orthogonal views, n = 127 cells from 3 mice for early tracing and 73 cells from 9 mice for late tracing). Published: July 1, 2019https://doi.org/10.1371/journal.pbio.3000326.We have g...
Source: Neuromics - July 7, 2019 Category: Neuroscience Tags: Neurogenesis Neuron-specific class III beta-tubulin Neuron-specific class III beta-tubulin antibody Tuj 1 Tuj 1 antibody Tuj-1 antibodies Source Type: news
FBS-Put it to Work
Priced RightWe provide, to our customers, the sameFetal Bovine Serum (FBS) we use in ourdefined media. This FBS enriched media is used in culturing all our human 2 and 3-D based Assays. Our FBS is of the highest quality and priced right at $379/500 ml.Here're some recent publications referencing its use.Gabriela Fernandes, Stephen T Vanyo, Shahad Bakheet Alsharif, Sebastiano Andreana, Michelle B Visser, Rosemary Dziak, Ph.D.Strontium Effects on Human Gingival Fibroblasts. https://doi.org/10.1563/aaid-joi-D-18-00253Douglas Dickinson, Shannon Xayaraj, Sarah Dickinson, Xueling Shao, and Stephen Hsu. Effect of ...
Source: Neuromics - June 27, 2019 Category: Neuroscience Tags: 3-D Cell based Assays Cell Cultures FBS Fetal Bovine Serum Source Type: news
Sex Differences on the Behavior of Human Brain Microvascular Endothelial Cells (HBMECS)
The Risk of StrokeThere are sex differences in risk for stroke and small vessel ischemic disease in the brain. Microvesicles (MV) derived from activated cells vary by cell of origin and the stimulus initiating their release. MV released from cells activated by inflammatory and thrombotic factors have the potential to disrupt endothelial cells of the brain microvasculature. Therefore, experiments were designed to identify sex differences in the phenotype of MV released from cultured human brain microvascular endothelial cells (HBMEC) in response to inflammatory and thrombotic stimuli (Biology of Sex Differences201910:26http...
Source: Neuromics - June 19, 2019 Category: Neuroscience Tags: Blood Brain Barrier brain microvascular endothelial cells HBMECs Microvasculature Stroke Source Type: news
Human Pancreatic CAFS and Tumor Dynamics
Extracellular Matrix (ECM) MattersOurHuman Pancreatic Cancer Fibroblasts were recently featured in a publication focusing on the role of the ECM on tumor dynamics. Andreas Stylianou, Vasiliki Gkretsi, Maria Louca, Lefteris C. Zacharia, and Triantafyllos Stylianopoulos (2019).Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts. J. R. Soc. Interface 16: 20190226. http://dx.doi.org/10.1098/rsif.2019.0226.Commercially available pancreatic native human FBs and,CAFs (cat. nos. SC00A5 and CAF08, respectively, Neuromics) were cultured in MSC-GRO (VitroPlus III, low serum, comple...
Source: Neuromics - May 29, 2019 Category: Neuroscience Tags: 3D collagen scaffolds Human Pancreatic Fibroblasts Pancreatic CAF-Stellate Cells pancreatic cancer Source Type: news
Neurofilament Antibodies-Check Them Out
Widely Used and Frequently PublishedOurNeurofilament Antibodies are well characterized and research ready. Here is a recent publication using one of ourNeurofilament Heavy Antibodies. Jennifer M. Hahn, Kelly A. Combs, Christopher M. Lloyd, Kevin L. McFarland, Steven T. Boyce, and Dorothy M. Supp.Identification of Merkel cells associated with neurons in engineered skin substitutes after grafting to full thickness wounds. PLoS One. 2019; 14(3): e0213325. Published online 2019 Mar 5. doi: 10.1371/journal.pone.0213325.Figures: Merkel cells in grafted ESS are associated with neurons expression neurofilament heavy (NF-M) by eigh...
Source: Neuromics - May 22, 2019 Category: Neuroscience Tags: Neurofilament Antibody Neurofilament Markers Neurofilament-H Antibody Neuronal Markers NF-H antibody Source Type: news
We Can Sell and Deliver FBS in Large Volumes
This is Includes Single LotsWe are pleased with the growth in our FBS business. This is being made possible, in part, to our ability to find the " sweet spot " by coupling low pricing with high quality.We offer all potential customers free samples to test with the idea that they find the " sweet spot. " This leads to happy customers and repeat business.Here's a volume shipment wrapped and ready to go.2 pallets of 700X500 ml. Bottles FBS.Need FBS? Just ask us. Learn more by emailing firstname.lastname@example.org. Thank you! (Source: Neuromics)
Source: Neuromics - May 13, 2019 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news
i-Fect Scores Again
This study is the first to demonstrate that the stabilization of HIF1A expression underpins the development of bortezomib-induced neuropathic pain. Crucially, these findings reveal that the initiation and maintenance of bortezomib-induced neuropathic pain are regulated by distinct mechanisms. (Source: Neuromics)
Source: Neuromics - May 13, 2019 Category: Neuroscience Tags: chemotherapy i-Fect RNAi siRNA siRNA delivery in-vivo Source Type: news
We Have Human Bone Marrow Derived Stem Cells
Pure and Potent-Only $655/500,000 CellsHuman Mesenchymal Stem Cells isolated from bone marrow and provided a low passage. These cells have the ability to be passaged five to 10 passages in our Low Serum, Complete Medium (#SC00B1); which is optimized for high growth rates, reduced doubling times, healthy cells and stability. This Product is manufactured, tested and validated in an ISO 9001/ISO13485/CLIA certified facility. (Source: Neuromics)
Source: Neuromics - April 27, 2019 Category: Neuroscience Tags: human Mesenchymal Stem Cell Based Assays Human Mesenchymal Stem Cells Source Type: news
Gut Brain Axis
Helicobacter pylori Induced Anxiety and AnorexiaOurPGP9.5 was used as a Hypothalamic Neuronal Marker in this study-Hajime Suzuki, Koji Ataka, Akihiro Asakawa, Kai-Chun Cheng, Miharu Ushikai, Haruki Iwai, Takakazu Yagi, Takeshi Arai, Kinnosuke Yahiro, Katsuhiro Yamamoto, Yoshito Yokoyama, Masayasu Kojima, Toshihiko Yada, Toshiya Hirayama, Norifumi Nakamura& Akio Inui (2019).Helicobacter pylori Vacuolating Cytotoxin A Causes Anorexia and Anxiety via Hypothalamic Urocortin 1 in Mice. Scientific Reports volume 9, Article number: 6011.Images: Ucn1- and DAPI-positive cells (yellow arrow heads), or Ucn1- and PGP9.5-positive c...
Source: Neuromics - April 16, 2019 Category: Neuroscience Tags: Gut-Brain Axis. Hypothalamus Helicobacter pylori Hypothalamic Neurons PGP9.5 Antibody Protein Gene Product 9.5 Source Type: news
Your Data Wanted
Reward is $50 Amazon Gift CardWe are always honored when customers share theirdata and images. More is better! This month we would like to reward you for any data or images featuring any of our products you share with us.Just e-mail Rose Ludescher, Manager of Customer Satisfaction, email@example.com, and she will e-mail you a $50 Amazon Gift Card.Example DataHUMAN PANCREATIC CAF-STELLATE CELLS-Stained with alpha-SMA + DAP1 20x. Courtesy of Emily Rodela, TGEN-Courtesy of Emila Rodela, T-Gen. (Source: Neuromics)
Source: Neuromics - April 3, 2019 Category: Neuroscience Source Type: news
Human and Animal Cardiomyocytes
Pure, Potent and Easy to CultureCheck out our hMSC Derived Human Cardiomyocytes-These cells are optimized to provide addition options for in-vitro testing of drug to drug candidate toxicities allowing researchers to rule out the ineffective and potentially small compounds/toxic compounds early in the process.Human Cardiomyocytes in CultureNeuromics also offersprimary rat and mouse cardiomyocyte tissue and disassociated cells. (Source: Neuromics)
Source: Neuromics - March 19, 2019 Category: Neuroscience Tags: cardiomyocytes human cardiomyocytes Mouse Cardiomyocytes Rat Cardiomyocytes Source Type: news
Featuring Neurofilament AntibodiesWe have the honor of ourNeuron-Glial Markers being referenced in manypublications. Here we wanted to feature some recent data from one of ourNeurofilament Antibodies.Fig. Merkel cells in grafted ESS are associated with neurons expression neurofilament heavy (NF-M) by eight weeks after grafting. Immunochemistry with antibodies against NF-H (red) and KRT20 (green) was used to localize neurons and Merkel cells, respectively, in ESS after grafting to mice. Nuclei were counterstained with DAPI (blue; B, D, F, H). Shown are cross sections of ESS at 4 weeks (A-B), 8 weeks (C-D), 12 weeks (E-F), a...
Source: Neuromics - March 7, 2019 Category: Neuroscience Tags: Glia Markers Neurofilament Antibody Neurofilament Markers Neuronal Markers NF-H antibody Source Type: news
Neuromics' Human Brain Pericytes Guide Axon Growth
Study Interactions Between Blood Vessels and Nerve CellsOurGFP-Labeled Human Brian Pericytes were used by Spinal Cord Injury Researchers to evaluate the efficacy of aligned microvessels to induce and control directional axon growth from neural progenitor cells in vitro and host axons in a rat spinal cord injury model. Interstitial fluid flow aligned microvessels generated from co-cultures of cerebral-derived endothelial cells and pericytes in a three-dimensional scaffold. Paul P. Partyka, Ying Jin, Julien Bouyer, Angelica DaSilva, George A. Godsey, Robert G. Nagele, Itzhak Fischer& Peter A. Galie (2019). Harnessin...
Source: Neuromics - February 27, 2019 Category: Neuroscience Tags: Axon growth axonal guidance Human Brain Pericytes Neurons Spinal cord injury Spinal cord injury repair spinal cord regeneration Source Type: news
HUVECS Guide Axon Growth
Study Interactions Between Blood Vessels and Nerve CellsOurGFP-Labeled Human Brian Pericytes were used, by researchers, to evaluate the efficacy of aligned microvessels to induce and control directional axon growth from neural progenitor cells in vitro and host axons in a rat spinal cord injury model. Interstitial fluid flow aligned microvessels generated from co-cultures of cerebral-derived endothelial cells and pericytes in a three-dimensional scaffold. Paul P. Partyka, Ying Jin, Julien Bouyer, Angelica DaSilva, George A. Godsey, Robert G. Nagele, Itzhak Fischer& Peter A. Galie (2019). Harnessing neurovascular i...
Source: Neuromics - February 27, 2019 Category: Neuroscience Tags: Axon growth axonal guidance Human Brain Pericytes Neurons Spinal cord injury Spinal cord injury repair spinal cord regeneration Source Type: news