Spectral features related to the auditory perception of twang-like voices
CONCLUSIONS: Based on the intra-rater reliability scores, four judges were identified as suitable to be included in the analyses. Results showed that the frequency of F1 and F2 correlated strongly with the auditory-perception of twang-like voices (0.90 and 0.74, respectively), whereas F3 showed a moderate negative correlation (-0.52). The frequency difference between F1 and F3 showed a strong negative correlation (-0.82). The mean energy between 1-2 kHz and 2-3 kHz correlated moderately (0.51 and 0.42, respectively). The frequency of F4 and F5, and the energy above 3 kHz showed weak correlations. Since the spectral changes...
Source: Logopedics, Phoniatrics, Vocology. - April 24, 2024 Category: Speech-Language Pathology Authors: Marcelo Sald ías O'Hrens Christian Castro V íctor M Espinoza Justin Stoney Camilo Quezada Anne-Maria Laukkanen Source Type: research

Perceived stress and brain connectivity in subthreshold depression: Insights from eyes-closed and eyes-open states
This study aimed to elucidate the relationship between eye-open (EO) and eye-closed (EC) states, perceived stress, and StD. We recruited 27 individuals with StD and 33 healthy controls, collecting resting state fMRI data under both EC and EO conditions. We combined intrinsic connectivity and seed-based functional connectivity analyses to construct the functional network and explore differences between EC and EO conditions. Graph theory analysis revealed weakened connectivity strength in the right superior frontal gyrus (SFG) and right median cingulate and paracingulate gyrus (MCC) among participants with StD, suggesting an...
Source: Brain Research - April 24, 2024 Category: Neurology Authors: Bin-Kun Huang Jun-He Zhou Ying Deng Chang-Hong Li Bai-Le Ning Zi-Yu Ye Xi-Chang Huang Mi-Mi Zhao Dian Dong Ming Liu De-Long Zhang Wen-Bin Fu Source Type: research

Autonomous artificial intelligence versus teleophthalmology for diabetic retinopathy
Conclusions: The comparison between the diagnosis provided by artificial intelligence based automated software and the reference clinical diagnosis showed that they can work at a level of sensitivity that is similar to that achieved by experts.PMID:38656241 | DOI:10.1177/11206721241248856 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 24, 2024 Category: Opthalmology Authors: Donatella Musetti Carlo Alberto Cutolo Monica Bonetto Mauro Giacomini Davide Maggi Giorgio Luciano Viviani Ilaria Gandin Carlo Enrico Traverso Massimo Nicol ò Source Type: research

Diagnostic interobserver agreement for thyroid fine-needle aspirates: Effects of reviewer experience and molecular diagnostics
CONCLUSIONS: Atypia of undetermined significance of thyroid FNAs harboring BRAF V600E is uncommon yet relatively reproducible, particularly among pathologists with experience. It is advisable to sequence BRAF across V600 in such cases.PMID:38656386 | DOI:10.1093/ajcp/aqae043 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 24, 2024 Category: Pathology Authors: Hamza N Gokozan Maria Mostyka Theresa Scognamiglio James P Solomon Shaham Beg Evan Stern Abha Goyal Momin T Siddiqui Jonas J Heymann Source Type: research

Histological Findings in the Eyes of Abcc6 Knockout Rat Model of Pseudoxanthoma Elasticum
DISCUSSION: The Abcc6-/- rat model shows that PXE can affect multiple ocular tissues beyond the calcification in Bruch's membrane noted in human eyes. Nodular calcific foci probably correspond to comet lesions seen in patients with PXE. The presence of ectopic calcium without inflammation distinguishes it from inflammatory calcium deposition in atherosclerosis. Further studies are needed to determine why PXE does not cause inflammatory infiltration.TRANSLATIONAL RELEVANCE: The Abcc6-/- murine model may be suitable for studying ocular PXE pathophysiology and ectopic calcification and developing effective therapies.PMID:3865...
Source: Atherosclerosis - April 24, 2024 Category: Cardiology Authors: Anahita Sehgal Tatyana Milman Qiaoli Li Jose S Pulido Source Type: research

Physiotherapy for continence and muscle function in prostatectomy: a randomised controlled trial
CONCLUSION: Supervised PFMT can improve postoperative UI and PFM function after RARP. Further studies are needed to confirm whether intra-anal pressure reflects PFM function and affects continence status in UI in men who have undergone RARP.PMID:38658057 | DOI:10.1111/bju.16369 (Source: Cancer Control)
Source: Cancer Control - April 24, 2024 Category: Cancer & Oncology Authors: Mifuka Ouchi Takeya Kitta Hiroki Chiba Madoka Higuchi Yui Abe-Takahashi Mio Togo Naohisa Kusakabe Sachiyo Murai Hiroshi Kikuchi Ryuji Matsumoto Takahiro Osawa Takashige Abe Nobuo Shinohara Source Type: research

Targeting inflammasomes and pyroptosis in retinal diseases-molecular mechanisms and future perspectives
Prog Retin Eye Res. 2024 Apr 22:101263. doi: 10.1016/j.preteyeres.2024.101263. Online ahead of print.ABSTRACTRetinal diseases encompass various conditions associated with sight-threatening immune responses and are leading causes of blindness worldwide. These diseases include age-related macular degeneration, diabetic retinopathy, glaucoma and uveitis. Emerging evidence underscores the vital role of the innate immune response in retinal diseases, beyond the previously emphasized T-cell-driven processes of the adaptive immune system. In particular, pyroptosis, a newly discovered programmed cell death process involving inflam...
Source: Cell Research - April 24, 2024 Category: Cytology Authors: Yimeng Sun Fan Li Yunfei Liu Dijie Qiao Xinyu Yao Guei-Sheung Liu Dequan Li Chuanle Xiao Tao Wang Wei Chi Source Type: research

Fast response/recovery and sub-ppm ammonia gas sensors based on a novel V2CTx@MoS2 composite
J. Mater. Chem. A, 2024, Accepted Manuscript DOI: 10.1039/D4TA00842A, PaperManyu Luo, Zhixian Gao, Zhenhong Jia, Shuang Li, Xingpeng Huang, Deshou Xiong, Sijin Cai Ammonia, a colorless gas with a strong irritating odor, is widely found in natural environments. Continuous exposure to ammonia, even at low concentrations, can cause irritation of the eyes, nose,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Mater. Chem. latest articles)
Source: RSC - J. Mater. Chem. latest articles - April 24, 2024 Category: Chemistry Authors: Manyu Luo Source Type: research

Daily briefing: The origins of bioluminescence in animals date back over half a billion years
Nature, Published online: 24 April 2024; doi:10.1038/d41586-024-01244-9Octocorals probably evolved the ability to make light when the first animals developed eyes. Plus, the WHO has redefined ‘airborne transmission’ and how artificial intelligence is changing weapons of war. (Source: Nature AOP)
Source: Nature AOP - April 24, 2024 Category: Research Authors: Flora Graham Source Type: research

Waardenburg syndrome type 2 with a de novo variant of the SOX10 gene: a case report
Waardenburg syndrome type 2 (WS2) has been reported to be a rare hereditary disorder, which is distinguished by vivid blue eyes, varying degrees of hearing impairment, and abnormal pigment deposition in the sk... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - April 24, 2024 Category: Genetics & Stem Cells Authors: Yuanyuan Li, Yuxue Chen, Yang Sun, Shouxin Li, Lingli Dong, Zongzhe Li and Guifen Shen Tags: Case Report Source Type: research

Sensors, Vol. 24, Pages 2718: Adaptation of Postural Sway in a Standing Position during Tilted Video Viewing Using Virtual Reality: A Comparison between Younger and Older Adults
This study aimed to investigate the effects of wearing virtual reality (VR) with a head-mounted display (HMD) on body sway in younger and older adults. A standing posture with eyes open without an HMD constituted the control condition. Wearing an HMD and viewing a 30°-tilt image and a 60°-tilt image in a resting standing position were the experimental conditions. Measurements were made using a force plate. All conditions were performed three times each and included the X-axis trajectory length (mm), Y-axis trajectory length (mm), total trajectory length (mm), trajectory length per unit time (mm/s), ...
Source: Sensors - April 24, 2024 Category: Biotechnology Authors: Tsubasa Tashiro Noriaki Maeda Takeru Abekura Rami Mizuta Yui Terao Satoshi Arima Satoshi Onoue Yukio Urabe Tags: Article Source Type: research

Correction to: Analgesic effect of oral paracetamol 1000  mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative pain: a single‑dose, randomized, and double‑blind study
(Source: European Journal of Clinical Pharmacology)
Source: European Journal of Clinical Pharmacology - April 24, 2024 Category: Drugs & Pharmacology Source Type: research

Transcervical Excision of Mixed Laryngocele: A Case Report with Step-by-step Surgical Guide
AbstractLaryngocele is the benign cystic dilatation of the laryngeal saccule which is a blind pouch arising from the anterior roof of the laryngeal ventricle and ascends in the loose areolar tissue of the pre-epiglottic space posterior to the thyroid cartilage. It is a rare clinical entity. We, hereby report a case of mixed laryngocele who presented with complain of both swelling in the neck and change in voice who was treated with transcervical surgical excision. A step-by-step surgical guide to demonstrate intra-operative procedure such that it can be standardized and reproduced by any ENT surgeon was the underlying rati...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 24, 2024 Category: ENT & OMF Source Type: research

Prognostic indicators of corneal ulcer clinical outcomes at a tertiary care center in the Bronx, New York
ConclusionIdentification of risk factors associated with a poor clinical prognosis can guide treatment and inform expectations for patients diagnosed with a corneal ulcer. Our study highlights the importance of timely diagnosis, work-up, and initiation of appropriate management, particularly in vulnerable populations where access to specialty care is logistically challenging. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - April 24, 2024 Category: Opthalmology Source Type: research

Comparison of B-Scan ultrasonography, ultra-widefield fundus imaging, and indirect ophthalmoscopy in detecting retinal breaks in cataractous eyes
Eye, Published online: 24 April 2024; doi:10.1038/s41433-024-03093-2Comparison of B-Scan ultrasonography, ultra-widefield fundus imaging, and indirect ophthalmoscopy in detecting retinal breaks in cataractous eyes (Source: Eye)
Source: Eye - April 24, 2024 Category: Opthalmology Authors: Ao Miao Jie Xu Kai Wei Peimin Lin Liangliang Niu Yumeng Shi Dongjin Qian Yi Lu Yongxiang Jiang Tianyu Zheng Source Type: research