Preservative-Free Fixed Combination of Tafluprost 0.0015% and Timolol 0.5% for Treatment-Naive Patients with Open-Angle Glaucoma
CONCLUSIONS: In this real-world observational study, once-daily treatment with PF tafluprost/timolol FC demonstrated clinically relevant and statistically significant efficacy, as well as safety and good tolerability, in treatment-naive patients diagnosed with POAG.PMID:38665112 | DOI:10.3341/kjo.2024.0021 (Source: Korean Journal of Ophthalmology : KJO)
Source: Korean Journal of Ophthalmology : KJO - April 26, 2024 Category: Opthalmology Authors: Teakkwan Rhee Jaeheon Kim Ahnul Ha Source Type: research

Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals
CONCLUSIONS: This pilot study demonstrates that successful subretinal delivery of gene therapy vectors is achievable using a direct injection without prior vitrectomy surgery.PMID:38666493 | DOI:10.1080/02713683.2024.2343335 (Source: Current Eye Research)
Source: Current Eye Research - April 26, 2024 Category: Opthalmology Authors: Zbynek Stranak Taras Ardan Yaroslav Nemesh Maria Toms Lyes Toualbi Richard Harbottle Zdenka Ellederova Lyubomyr Lytvynchuk Goran Petrovski Jan Motlik Mariya Moosajee Igor Kozak Source Type: research

Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals
CONCLUSIONS: This pilot study demonstrates that successful subretinal delivery of gene therapy vectors is achievable using a direct injection without prior vitrectomy surgery.PMID:38666493 | DOI:10.1080/02713683.2024.2343335 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Zbynek Stranak Taras Ardan Yaroslav Nemesh Maria Toms Lyes Toualbi Richard Harbottle Zdenka Ellederova Lyubomyr Lytvynchuk Goran Petrovski Jan Motlik Mariya Moosajee Igor Kozak Source Type: research

Observation on the tilt and decentration of multifocal intraocular lens with optic capture in Berger space for pediatric cataract
ConclusionsThe follow-up results suggest the tilt and decentration of multifocal IOL implantation with optic capture in Berger space remain stable in an acceptable range within 2  years after cataract surgery in children above the age of 5.Trialregistration :The study was approved by the Ethics Committee of Qingdao Eye Hospital, and registered on Chinese Clinical Trial Registry (ChiCTR identifier: 1900023155). (Source: International Ophthalmology)
Source: International Ophthalmology - April 26, 2024 Category: Opthalmology Source Type: research

Quantitative analysis of the eyelid curvature in patients with blepharoptosis
The aim of this study was to evaluate the ability of two novel eyelid curvature measurements to distinguish between normal eyes and different severities of blepharoptosis. (Source: BMC Medical Imaging)
Source: BMC Medical Imaging - April 26, 2024 Category: Radiology Authors: Elias Khalili Pour, Tahereh Mahmoudi, Hooman Ahmadzadeh, Seyed Mohsen Rafizadeh and Hamid Riazi-Esfahani Tags: Research Source Type: research

Efficacy and safety of a new low-volume PEG with citrate and simethicone bowel preparation for pediatric elective colonoscopy: Phase 3 RCT
Conclusions In children aged 6 to 17 years, the new low-volume product PMF104 is non-inferior to the reference PEG-ES in terms of bowel cleansing, safety, and tolerability, with slightly better results in compliance, palatability, and acceptability. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Endoscopy International Open)
Source: Endoscopy International Open - April 26, 2024 Category: Gastroenterology Authors: Russo, Giusy Alvisi, Patrizia Romano, Claudio Angelino, Giulia Lemale, Julie Lachaux, Alain Lionetti, Paolo Veereman, Genevieve Ruggiero, Cosimo Padovani, Michela Tacchi, Raffaella Cenci, Fabio Cucchiara, Salvatore Oliva, Salvatore Tags: Original article Source Type: research

Long-term results of anterior chamber iris claw intraocular lens implantation in children with ectopia lentis in Marfan syndrome
To report the long-term clinical and endothelial cell count (ECC) results of lensectomy with primary anterior chamber iris claw lens implantation in the eyes of patients ≤18-year-old with ectopia lentis due to Marfan syndrome. (Source: Journal of AAPOS)
Source: Journal of AAPOS - April 26, 2024 Category: Opthalmology Authors: Elsbeth J.T. van Zeeburg, Marije L. Sminia, Nicoline E. Schalij-Delfos Tags: Major Article Source Type: research

Selective laser trabeculoplasty in the treatment of juvenile open angle glaucoma patients under 25  years of age
ConclusionSLT is an effective and reliable method for JOAG treatment. (Source: International Ophthalmology)
Source: International Ophthalmology - April 26, 2024 Category: Opthalmology Source Type: research

Neurotrophic keratopathy: General features and new therapies.
This article presents a comprehensive review of the disease, providing an update relevant to ophthalmologists on pathogenesis, diagnosis, treatment options, and novel therapies targeting pathophysiological pathways. (Source: Survey of Ophthalmology)
Source: Survey of Ophthalmology - April 26, 2024 Category: Opthalmology Authors: Guillermo Raul Vera-Duarte, David Jimenez-Collado, Nicol ás Kahuam-López, Arturo Ramirez-Miranda, Enrique O. Graue-Hernandez, Alejandro Navas, Mark I Rosenblatt Tags: Review article Source Type: research

Cancers, Vol. 16, Pages 1687: Development of an Artificial-Intelligence-Based Tool for Automated Assessment of Cellularity in Bone Marrow Biopsies in Ph-Negative Myeloproliferative Neoplasms
o Andrea Ronchi The cellularity assessment in bone marrow biopsies (BMBs) for the diagnosis of Philadelphia chromosome (Ph)-negative myeloproliferative neoplasms (MPNs) is a key diagnostic feature and is usually performed by the human eyes through an optical microscope with consequent inter-observer and intra-observer variability. Thus, the use of an automated tool may reduce variability, improving the uniformity of the evaluation. The aim of this work is to develop an accurate AI-based tool for the automated quantification of cellularity in BMB histology. A total of 55 BMB histological slides, diagnosed as Ph- MPN b...
Source: Cancers - April 26, 2024 Category: Cancer & Oncology Authors: Giuseppe D ’Abbronzo Antonio D ’Antonio Annarosaria De Chiara Luigi Panico Lucianna Sparano Anna Diluvio Antonello Sica Gino Svanera Renato Franco Andrea Ronchi Tags: Article Source Type: research

Vogt –Koyanagi–Harada disease after SARS‐CoV‐2 infection: Case report and literature review
ConclusionDespite the unclear causality, it is important for ophthalmologists and physicians to be recognizant of the possible association between VKH disease and COVID-19. SARS-CoV-2 may play a potential immunological triggering role in VKH disease. However, further in-depth research is necessary to investigate the clinical and epidemiological features, as well as the underlying mechanisms of this association. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 25, 2024 Category: Allergy & Immunology Authors: Hui Zou, Ke Zhang, Xuan Chen, Sha Sha Tags: SHORT REPORT Source Type: research

Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension
CONCLUSION: Large-scale survival analyses provide the expected duration of treatment success from topical glaucoma medication.PMID:38664004 | DOI:10.1136/bjo-2023-323708 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Dun Jack Fu Ebenezer Ademisoye Vanessa Shih Andrew Ian McNaught Anthony Khawaja Source Type: research

Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension
CONCLUSION: Large-scale survival analyses provide the expected duration of treatment success from topical glaucoma medication.PMID:38664004 | DOI:10.1136/bjo-2023-323708 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Dun Jack Fu Ebenezer Ademisoye Vanessa Shih Andrew Ian McNaught Anthony Khawaja Source Type: research

Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension
CONCLUSION: Large-scale survival analyses provide the expected duration of treatment success from topical glaucoma medication.PMID:38664004 | DOI:10.1136/bjo-2023-323708 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Dun Jack Fu Ebenezer Ademisoye Vanessa Shih Andrew Ian McNaught Anthony Khawaja Source Type: research

Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension
CONCLUSION: Large-scale survival analyses provide the expected duration of treatment success from topical glaucoma medication.PMID:38664004 | DOI:10.1136/bjo-2023-323708 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Dun Jack Fu Ebenezer Ademisoye Vanessa Shih Andrew Ian McNaught Anthony Khawaja Source Type: research