The effectiveness of ocriplasmin versus surgery for the treatment of macular holes: A systematic review and meta-analysis.
CONCLUSIONS: Results suggested 92% macular hole closure after vitrectomy compared to 34% after ocriplasmin. A significant improvement in visual acuity of patients was seen after both treatments. More good quality randomized controlled trials are required to make strong conclusions. PMID: 32731755 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 30, 2020 Category: Opthalmology Authors: Yu BE, Sheidow T, Sambhi RS, Hooper P, Malvankar-Mehta MS Tags: Eur J Ophthalmol Source Type: research

Papillophlebitis in a COVID-19 patient: Inflammation and hypercoagulable state.
CONCLUSION: The importance of this case lies in the possible association of papillophlebitis with the new Covid-19 disease. We believe that the inflammatory reaction and the coagulation alteration present in our patient due to Sars-Cov2 coronavirus may have acted as risk factors for the development of papillophlebitis. PMID: 32735134 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 30, 2020 Category: Opthalmology Authors: Insausti-García A, Reche-Sainz JA, Ruiz-Arranz C, López Vázquez Á, Ferro-Osuna M Tags: Eur J Ophthalmol Source Type: research

Acquired retinoschisis and vitreous hemorrhage as unusual findings in choroideremia: Case report.
CONCLUSION AND IMPORTANCE: We have reported fundoscopic and OCT features of peripheral-acquired retinoschisis with vascular abnormalities in a patient with choroideremia. OCT examination is extremely useful in clinical evaluation of the peripheral retinal alterations in these cases, where the absence of the retinal pigment epithelium and the choriocapillaris pose many diagnostic difficulties. PMID: 32729722 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 30, 2020 Category: Opthalmology Authors: Mucciolo DP, Murro V, Giorgio D, Sodi A, Passerini I, Virgili G, Giansanti F Tags: Eur J Ophthalmol Source Type: research

Peripapillary capillary density in acute angle closure crisis and angle closure suspect: A structure, flow and function correlation study.
CONCLUSIONS: Peripapillary vessel density was lower in AACC eyes than in suspects and control eyes. OCT-A parameters could be a more sensitive marker than OCT parameters after an AACC attack as evident on ROC analysis. PACS remains a clinical diagnosis as we could not find any significant differences in OCT or OCT-A parameters between suspects and normal healthy controls. PMID: 32729735 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 30, 2020 Category: Opthalmology Authors: Allam RS, Eltanamly RM, Raafat KA Tags: Eur J Ophthalmol Source Type: research

The results of Baerveldt glaucoma implant surgery performed with the scleral flap and patch technique.
We report the results of Baerveldt glaucoma implant (BGI) surgery performed with the scleral flap and patch technique. PATIENTS AND METHODS: This was a retrospective analysis of 97 consecutive patients (107 eyes) who underwent BGI surgery with the scleral flap and patch, and were followed up for>1 year. We evaluated the patients' post-operative intraocular pressure (IOP), corneal endothelial cell density, and complications (corneal edema, Hoffmann elbow exposure). RESULTS: The preoperative IOP was 32.9 ± 8.6 mmHg. BGI surgery significantly decreased the IOP to 11.1 &pl...
Source: European Journal of Ophthalmology - July 30, 2020 Category: Opthalmology Authors: Tojo N, Hayashi A Tags: Eur J Ophthalmol Source Type: research

Huge peripapillary staphyloma with craniofacial clefts: A case report.
CONCLUSION: Peripapillary staphyloma and craniofacial clefts are two dissimilar rare congenital anomalies. In this patient, we firstly observed the co-existence of the two defects, which may provide the experience to the diagnosis and treatment of peripapillary staphyloma and craniofacial clefts. This case also gives us the pathogenic inspiration for further studies of peripapillary staphyloma and craniofacial clefts. PMID: 32720522 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Yu F, Fu Y Tags: Eur J Ophthalmol Source Type: research

Augmented vertical rectus transpositions: Intraoperative measurement of torsion following sequential muscle detachment.
CONCLUSION: The SR and IR have different torsional effects, which only appears when more than half of the fibers are detached. Augmented transposition does not cause any additional torsional effects. This intraoperative monitoring system can be used to detect unintended torsional complications, especially during transposition surgery. PMID: 32720807 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Serafino M, Scaramuzzi M, Magli A, Nucci P Tags: Eur J Ophthalmol Source Type: research

Vertical restrictive strabismus associated with proptosis: Similar clinical signs, different etiopathogenetic causes. A report of three patients.
CONCLUSION: Although proptosis and acquired vertical restrictive strabismus are most commonly associated with thyroid associated orbitopathy (TAO), they can also be a manifestation of many other conditions and the differential diagnosis can be particularly challenging. The three reported cases presented indeed with similar clinical features but had three distinct underlying orbital etiologies, two of which were extremely uncommon. PMID: 32720817 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Savino G, Petrone G, Volpe G, Midena G, Grimaldi G, Fiorentino V, Maceroni M Tags: Eur J Ophthalmol Source Type: research

Comparison between Fundus Automated Perimetry and Humphrey Field Analyzer: Performance and usability of the Fundus Automated Perimetry and Humphrey Field Analyzer in healthy, ocular hypertensive, and glaucomatous patients.
Abstract PURPOSE: We compared the performance and usability of the Fundus Automated Perimetry (FAP) and Humphrey Field Analyzer (HFA) in patients with glaucoma, ocular hypertension, and healthy subjects. MATERIALS AND METHODS: A total of 60 participants, divided in three groups of 20, glaucoma (POAG), ocular hypertension (OHT), and controls group, underwent a HFA test 24-2 SITA standard and a FAP test 24-2 ZEST sequence, in randomized order. The mean differences between perimeters of mean deviation (MD), pattern standard deviation (PSD) were correlated using the t-test and the Bland-Altman plot while executio...
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Morbio R, Longo C, De Vitto AML, Comacchio F, Della Porta LB, Marchini G Tags: Eur J Ophthalmol Source Type: research

Conserved regression patterns of retinopathy of prematurity after intravitreal ranibizumab: A class effect.
CONCLUSION: IVR conforms to the previously described regression patterns following intravitreal bevacizumab for ROP indicative of a class effect. Follow-up using FA might help to optimize the management of these infants after injection of the drug. PMID: 32722932 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Ji MH, Moshfeghi DM, Shields RA, Bodnar Z, Ludwig CA, Callaway NF, Orazi L, Amorelli GM, Lepore D Tags: Eur J Ophthalmol Source Type: research

Patient satisfaction with the ocular surface individualized medical program.
Abstract PURPOSE: To improve the medical management system and the quality of medical treatment, this study aimed to assess patient satisfaction related to an ocular surface individualized medical program for dry eye, and identified patient needs that should be addressed in future. METHODS: We enrolled 166 patients from the dry eye clinic at the Peking University Third Hospital from December 2017 to May 2019. An investigator followed up with all patients by telephone 2 months after the first assessment of overall patient satisfaction, expectations, and experiences. We determined patient satisfaction us...
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Hao R, Chou Y, Wan Y, Jiang X, Li X Tags: Eur J Ophthalmol Source Type: research

Efficacy of omega-3 fatty acids and punctal plugs in the prevention of isotretinoin-associated ocular surface disease.
CONCLUSION: Our cohort highlights the beneficial effects of the combination of O3FAs supplementation with PPs in the prevention of isotretinoin-associated OSD in this sample study. PMID: 32722939 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Elhamaky TR Tags: Eur J Ophthalmol Source Type: research

Swept-source optical coherence tomography angiography vitreo-retinal segmentation in proliferative diabetic retinopathy.
CONCLUSION: Three segmentation protocols (VRS, OVS and CVS) with different but complementary characteristics, allowed a reproducible and standardised investigation of NVD and NVE. The proposed new SS-OCTA cortical vitreous segmentation protocols may be of value when identifying and assessing NV-activity (VRS, OVS and CVS) or NV-regression (VRS) in PDR and therefore, response to therapy. PMID: 32722940 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Papayannis A, Tsamis E, Stringa F, Iacono P, Battaglia Parodi M, Stanga PE Tags: Eur J Ophthalmol Source Type: research

Optical coherence tomography angiography in Tuberous sclerosis complicated with macular choroidal neovascularization.
This study describe the optical coherence tomography angiography (OCTA) features of a young patient with Tuberous sclerosis complicated with CNV unilateral macular choroidal neovascularization during the ranibizumab therapy. OCTA scans of macular region of right eye, revealed a dense microvascular network confirming the diagnosis of CNV. After four monthly intravitreal injections, OCTA revealed a decrease of size and activity of CNV. OCTA is a valid, non-invasive, dyeless, and reliable method that could improve the diagnosis and management of CNV in child with Tuberous sclerosis. PMID: 32715772 [PubMed - as supplied b...
Source: European Journal of Ophthalmology - July 27, 2020 Category: Opthalmology Authors: Fortunato M, Turtoro A, Cennamo G, Nardella C Tags: Eur J Ophthalmol Source Type: research

Blunt ocular trauma in patients over 70: Clinical characteristics and prognosis.
Abstract PURPOSE: To describe the mechanisms and outcomes of open globe injuries (OGIs) in patients 70 years or older. METHODS: A retrospective chart review of patients from two large academic centers in Israel who were underwent surgery for OGI. Data was collected from surgical and clinic charts. Anatomical and functional results were recorded as well any additional surgeries and complications. RESULTS: Thirty-two eyes of 32 patients were included. The mechanism of OGI consisted of blunt trauma with ocular rupture secondary to falls. All eyes underwent immediate primary closure of the corneal and...
Source: European Journal of Ophthalmology - July 27, 2020 Category: Opthalmology Authors: Vidne-Hay O, Fogel Levin M, Luski S, Moisseiev J, Moisseiev E Tags: Eur J Ophthalmol Source Type: research

Corneal biomechanical outcome of collagen cross-linking in keratoconic patients evaluated by Corvis ST.
In this study, 67 eyes of 67 patients with progressive keratoconus (KCN) treated with "Epithelium-off" CXL were evaluated. Patients with stages 1 or 2 of KCN and a corneal thickness of at least 400 μm at the thinnest point were included. Standard ophthalmologic examinations were carried out for all patients. The topographic and biomechanical measurements of the cornea were obtained by Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany) and Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) preoperatively and 6-month postoperatively. RESULTS: The mean age of the participants was 21.68&...
Source: European Journal of Ophthalmology - July 25, 2020 Category: Opthalmology Authors: Jabbarvand M, Moravvej Z, Shahraki K, Hashemian H, Ghasemi H, Berijani S, Amiri Z, Jamali A Tags: Eur J Ophthalmol Source Type: research

Safety and visual outcomes following Iris-claw phakic intraocular lens bilensectomy.
CONCLUSION: Bilensectomy was successful in improving UCVA and CDVA with an acceptable refractive outcome. Significant loss of ECD was found after surgery. The results recommend a larger ACD as selection criteria when choosing to implant an Artisan lens, and a close postoperative monitoring of the endothelial cell count. PMID: 32715788 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 25, 2020 Category: Opthalmology Authors: Vargas V, Marinho A, El Sayyad F, Alio Del Barrio JL, Alio JL Tags: Eur J Ophthalmol Source Type: research

Topography-based customized trans-epithelial phototherapeutic keratectomy for anterior corneal scar removal.
CONCLUSION: Topography-based customized PTK appears to be an effective novel technique for the management of superficial corneal scars with minimal induced refractive change. This technique holds promise as an alternative in the targeted management of superficial corneal scars, traditionally treated by conventional PTK, without significant ablation of normal tissue. PMID: 32703002 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 24, 2020 Category: Opthalmology Authors: Shetty R, Shroff R, Chhabra A, Arora R, Lalgudi VG Tags: Eur J Ophthalmol Source Type: research

Bcl-2, p53, and Ki-67 expression in pterygium and normal conjunctiva and their relationship with pterygium recurrence.
This study aimed to investigate the role of apoptosis and proliferation in pterygium formation and recurrence. MATERIALS AND METHODS: In this study, p53, Bcl-2, and Ki-67 expression levels were evaluated in primary pterygium (n = 35) and recurrent pterygium (n = 32) tissue samples and compared with normal conjunctiva (n = 30) tissue samples. In addition, recurrent pterygiums were divided into three groups based on recurrence time, and their p53, Bcl-2, and Ki-67 expression levels were compared. RESULTS: The results show that p53, Bcl-2, and Ki-67 expression levels were si...
Source: European Journal of Ophthalmology - July 24, 2020 Category: Opthalmology Authors: Turan M, Turan G Tags: Eur J Ophthalmol Source Type: research

Conjunctivitis as sole symptom of COVID-19: A case report and review of literature.
CONCLUSION: This phenomenon shows that conjunctivitis may occur as a sole manifestation of COVID-19 which needs to be carefully evaluated by health care workers and eye care professionals during the pandemic. PMID: 32703010 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 24, 2020 Category: Opthalmology Authors: Ozturker ZK Tags: Eur J Ophthalmol Source Type: research

Delayed metastasis in patients with intraocular retinoblastoma: A review of three cases.
CONCLUSION: Long-term follow-up of RB cases is mandatory. In spite of intraocular tumor regression, metastasis can still occur many years after treatment of RB. PMID: 32703017 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 24, 2020 Category: Opthalmology Authors: Vempuluru VS, Jakati S, Kaliki S Tags: Eur J Ophthalmol Source Type: research

Comment on: Ranibizumab and aflibercept intravitreal injection for treatment na ïve and refractory macular oedema in branch retinal vein occlusion.
Comment on: Ranibizumab and aflibercept intravitreal injection for treatment naïve and refractory macular oedema in branch retinal vein occlusion. Eur J Ophthalmol. 2020 Jul 24;:1120672120945103 Authors: Elkazza SA, Hogg HJ, Di Simplicio S, Dlay SS PMID: 32703021 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 24, 2020 Category: Opthalmology Authors: Elkazza SA, Hogg HJ, Di Simplicio S, Dlay SS Tags: Eur J Ophthalmol Source Type: research

22q12.3-q13.1 microdeletion including SOX10 causes atypical Waardenburg syndrome.
CONCLUSION: Our results suggest that a deletion of 1.99 megabase (including SOX10) acts as a dominant pathogenic variant on the clinical presentations of this patient with atypical Waardenburg syndrome. PMID: 32703023 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 24, 2020 Category: Opthalmology Authors: Zhang W, Xiao L, Chen B, Xu Y, Yan N Tags: Eur J Ophthalmol Source Type: research

Evolution of corneal flattening after repeated corneal cross-linking during a 6-year follow-up.
CONCLUSION: Repeated CXL can induce an excessive corneal flattening more pronounced during the first years of follow-up followed by stabilization thereafter. PMID: 32703026 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 24, 2020 Category: Opthalmology Authors: Grentzelos MA, Voulgari N, Giacuzzo C, Droutsas K, Kymionis GD Tags: Eur J Ophthalmol Source Type: research

Detection of serum uric acid in primary open angle glaucoma: A pilot study.
Abstract PURPOSE: To assess the association between the serum levels of uric acid (UA) and primary open-angle glaucoma (POAG). METHODS: In this pilot study, 46 eyes of 23 patients with a clinical history of POAG and 30 eyes of 15 healthy subjects were included. All patients underwent a complete ophthalmological examination, including best corrected visual acuity (BCVA), intraocular pressure (IOP), and gonioscopy. Visual field parameters, such as mean deviation (MD) and pattern standard deviation (PSD), and optical coherence tomography (OCT) values of the optic nerve head, including retinal nerve fiber layer (...
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Serra R, Coscas F, Pinna A, Peri M, Zucca I, Sellam A, Giancipoli E, Boscia F Tags: Eur J Ophthalmol Source Type: research

Medium-term tamponade with vitrectomy and perfluorodecalin for the management of complex retinal detachments.
Abstract PURPOSE: To describe the clinical presentation, anatomical and visual outcome of a series of patients in our department with complex retinal detachments, managed with vitrectomy and perfluorodecalin (PFD) for medium-term tamponade. STUDY DESIGN: Retrospective case series. METHODS: Retrospective analysis of the medical records of all patients in the last 6 years presenting with complex retinal detachment managed with vitrectomy where PFD was used as a medium-term tamponade. RESULTS: A total of 85 eyes in 85 patients were included in the study, with a mean follow-up period of 16.0&thin...
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Chehade LK, Guo B, Chan W, Gilhotra J Tags: Eur J Ophthalmol Source Type: research

A case of undiagnosed X-linked retinoschisis presenting as unilateral macular demarcation line.
CONCLUSION: XLRS is the most frequent cause of macular retinoschisis. The hallmark of XLRS is the evidence of a foveoschisis presenting with a characteristic spoke-wheel aspect in patients younger than 30 years of age. It is important to recognize uncommon presentations of XLRS so that the correct diagnosis is made, in order to provide the patients with appropriate genetic counseling and therapeutic care. PMID: 32698614 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Cozzupoli GM, Amoroso F, Bacquet JL, Miere A, Mouallem-Beziere A, Souied E Tags: Eur J Ophthalmol Source Type: research

Mitigation of traumatic blepharoptosis with "central levator tuck": A novel approach in upper eyelid repair.
CONCLUSION: We describe a simple and effective "central levator tuck" technique for traumatic eyelid laceration repair with optimal functional and cosmetic outcome while reducing the development of blepharoptosis in four patients. PMID: 32698616 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Mehta A, Thakur U, Saini M, Adiga S, Grewal SS, Kashyap H, Singh SR, Singh M, Pujari A Tags: Eur J Ophthalmol Source Type: research

Comparison of corneal biomechanical changes after LASIK and F-SMILE with CorVis ST.
Abstract PURPOSE: To evaluate changes in corneal biomechanics after LASIK and F-SMILE. SETTING: Elite Eye Center, Tanta, Egypt. DESIGN: Prospective, randomized, unmasked, interventional comparative case series. PATIENTS AND METHODS: A total of 60 eyes were equally divided into two groups; group A: received LASIK and group B: received F-SMILE. Pentacam and CorVis ST parameters were compared before and 6 months after procedures. P ⩽ 0.05 was used for significance of results. RESULTS: bIOP decreased by 0.762 ± 1.211 mmHg in group A (p =&thi...
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Abd El-Fattah EA, El Dorghamy AA, Ghoneim AM, Saad HA Tags: Eur J Ophthalmol Source Type: research

The use of topical cyclosporine A 0.05% as treatment for primary alacrimia in Allgrove syndrome.
CONCLUSION: It is important to emphasize the relevance of establishing an early diagnosis through a complete multidisciplinary clinical examination and a study of adrenal function. The treatment of dry eye in these patients is difficult to manage, with topical immunomodulators such as cyclosporine A as a good alternative when lubricants are insufficient. To our knowledge this is the first case of subjective and objective improvement of dry eye using cyclosporine A 0.05% in a case of alacrimia in triple A syndrome. Allgrove syndrome presentation does not always manifest with the classic triad and some symptoms may be not pr...
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Botella García J, Lázaro-Rodríguez V, de la Paz MF Tags: Eur J Ophthalmol Source Type: research

The role of mitomycin C and porcine extracellular matrix in phacotrabeculectomy.
Abstract PURPOSE: To compare between mitomycin C alone, porcine extracellular matrix alone, and combined low dose mitomycin C with porcine extracellular matrix in term of efficacy and safety in phaco-trabeculectomy surgery. STUDY DESIGN: Prospective comparative. METHODS: Sixty eyes of 60 patients complaining of primary open angle glaucoma and cataract, undergoing phaco-trabeculectomy, were distributed into three groups: group I: surgery was augmented with mitomycin C, group II with porcine extracellular matrix, and group III with porcine extracellular matrix combined with low dose mitomycin C. Intraocula...
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Hamdi MM, Hamdi IM Tags: Eur J Ophthalmol Source Type: research

Fluorescent angiography imaging of intravitreal active bleeding, due to deep venous thrombosis concomitant to Fournier gangrene.
CONCLUSION: Active retinal bleeding has been reported only twice in the past, in these cases, it was attributed to superficial venous vessel rupture due to vitreous traction or Valsalva-like retinopathy at the site of neovascularization. Active retinal vein bleeding during a fluorescein angiography, secondary to deep venous thrombosis due to Fournier gangrene, has not been previously reported. PMID: 32700553 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Panayiotis C, Ioannis K Tags: Eur J Ophthalmol Source Type: research

Corneal optical density in Fuchs endothelial dystrophy determined by anterior segment optical coherence tomography.
CONCLUSION: This study presents corneal optical density by AS-OCT as an objective value for corneal changes in FECD. Complementing other diagnostic tools in FECD the assessment of corneal optical density may identify progression of FECD, gauge novel therapeutic strategies and support risk and benefit analyses for corneal surgery. PMID: 32700559 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Wertheimer CM, Elhardt C, Wartak A, Luft N, Kassumeh S, Dirisamer M, Siedlecki J, Vounotrypidis E, Priglinger SG, Mayer WJ Tags: Eur J Ophthalmol Source Type: research

Cauda equina syndrome as the initial presentation of uveal melanoma metastasis.
CONCLUSION AND IMPORTANCE: Optic nerve invasion in uveal melanoma may lead to neurotropic spread of melanoma cells with risk of intracranial and spinal cord metastasis. Neurological symptoms should raise the suspicion of clinicians regarding this complication, which is associated with increased melanoma-related mortality. PMID: 32700563 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Hanout M, Kamil ZS, Alrjoub M, Laperriere N, Altomare F, Krema H Tags: Eur J Ophthalmol Source Type: research

Wide-angle 3D viewing system with valved trocar applied to chandelier-assisted scleral buckling.
CONCLUSION: The use of a digital three-dimensional (3D) visualization system, coupled with the positioning of a single 25 gauge valved trocar with chandelier, dramatically simplifies the traditional SB and flattens its learning curve, making this procedure more accessible to young surgeons. In addition, the better visualization capability yields to higher possibility to detect and treat all retinal lesions. PMID: 32700570 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: La Spina C, Del Turco C, Bogetto C, Panico E, Giobbio DC, Panico C Tags: Eur J Ophthalmol Source Type: research

Standardized pachymetry-assisted manual lamellar dissection for Descemet stripping endothelial keratoplasty.
sa LB Abstract PURPOSE: To present an alternative technique (Pachy-DSEK) for the manual preparation of thin endothelial lamellae in Descemet stripping endothelial keratoplasty (DSEK), as well as to evaluate its visual and anatomic outcomes. METHODS: A retrospective chart review was conducted in 15 cases who underwent DSEK at a private eye clinic in Brazil (INOB, Brasília) from June 2017 to December 2019. All patients had ocular comorbidities and relative contraindications to Descemet membrane endothelial keratoplasty (DMEK). All endothelial lamellae were manually prepared by using a standardized techni...
Source: European Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: Bertino P, Magalhães RS, de Souza Junior CJ, Prazeres TMB, de Sousa LB Tags: Eur J Ophthalmol Source Type: research

Combined brachytherapy and vitreoretinal surgery for a large retinal capillary hemangioma with exudative retinal detachment.
CONCLUSION: Ru-106 BT and scleral buckling concurrent approach can be an effective treatment modality in selected cases of large RCHs, followed by PPV to remove eventual vitreo-retinal tractions. PMID: 32693625 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: Barca F, Vicini G, Nicolosi C, Pieretti G, Caporossi T, Rizzo S, Giansanti F, Mazzini C Tags: Eur J Ophthalmol Source Type: research

Corneal collagen cross-linking for management of keratoconus in patients affected by Tourette syndrome.
CONCLUSION: Patients with keratoconus and TS should be observed frequently to document topographical and refractive changes, and in case of progressing disease, CXL should be performed in order to prevent further progression. PMID: 32686514 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 20, 2020 Category: Opthalmology Authors: Knutsson KA, Paganoni G, Ambrosio O, Ferrari G, Rama P Tags: Eur J Ophthalmol Source Type: research

Repeatability of whole-cornea measurements using a new swept-source optical coherence tomographer.
CONCLUSIONS: The ANTERION SS-OCT showed good repeatability when reconstructed different parameters for the whole cornea. This device produces measurements with high repeatability that could be useful for clinical research. PMID: 32686488 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 18, 2020 Category: Opthalmology Authors: Tañá-Rivero P, Aguilar-Córcoles S, Ruiz-Mesa R, Montés-Micó R Tags: Eur J Ophthalmol Source Type: research

Brain-derived neurotrophic factor in non-proliferative diabetic retinopathy with diabetic macular edema.
Abstract PURPOSE: To investigate aqueous humor (AH) and serum levels of brain-derived neurotrophic factor (BDNF) in non-proliferative diabetic retinopathy (NPDR) patients with diabetic macular edema (DME). METHODS: The prospective study consists of 20 patients with DME NPDR, 20 patients with no-DME NPDR, and 20 healthy control subjects. Serum and AH samples were obtained during cataract surgery and intravitreal injection. Serum and AH levels of BDNF were measured by enzyme-linked immunosorbent assay. RESULTS: The mean serum levels of BDNF were lower in both NPDR groups compared to the control group (DME ...
Source: European Journal of Ophthalmology - July 18, 2020 Category: Opthalmology Authors: Jun YH, Kim ST Tags: Eur J Ophthalmol Source Type: research

Morning glory optic nerve in Aicardi syndrome: Report of a case with fluorescein angiography.
CONCLUSION: Patients with Aicardi syndrome can have morning glory optic nerve anomaly and PFV. Using FA under anesthesia to detect these abnormalities help in estimating the extend of the disease and its complications, which allows for better management of the complications. PMID: 32674592 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 16, 2020 Category: Opthalmology Authors: Al-Moujahed A, Callaway NF, Ludwig CA, Rayess N, Wood E, Moshfeghi DM Tags: Eur J Ophthalmol Source Type: research

Optical coherence tomography angiography in myopic peripapillary intrachoroidal cavitation complicated by choroidal neovascularization.
Abstract PURPOSE: To detect the vessel density (VD) of the radial peripapillary capillary (RPC) in eyes affected by pathological myopia with or without a peripapillary intrachoroidal cavitation (PICC) and in eyes with PICC complicated by choroidal neovascularization (CNV), using optical coherence tomography angiography (OCTA). METHODS: We prospectively enrolled highly myopic patients from January 2016 to December 2019 at the Eye Clinic of the University of Naples "Federico II." We divided included patients into three groups: group 1 including patients with PICC complicated by CNV; group 2 including ...
Source: European Journal of Ophthalmology - July 16, 2020 Category: Opthalmology Authors: Comune C, Montorio D, Cennamo G Tags: Eur J Ophthalmol Source Type: research

Extensive conjunctival melanoma successfully treated with surgical resection and pre- and postoperative topical mitomycin C.
CONCLUSIONS: The patient was closely followed-up after the treatment, without any local or distant recurrence at 32 months. PMID: 32674607 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 16, 2020 Category: Opthalmology Authors: Mazzini C, Pieretti G, Vicini G, Nicolosi C, Virgili G, Giansanti F Tags: Eur J Ophthalmol Source Type: research

Use of new-generation hybrid contact lenses for managing challenging corneas.
Abstract INTRODUCTION: To evaluate the safety and efficacy of new-generation hybrid contact lenses (HCL) among patients with irregular astigmatism. METHODS: Medical records of 25 patients fit with new-generation HCL (Eyebrid® and AirFlex®) were retrospectively reviewed. The data collected included etiology of irregular astigmatism, uncorrected visual acuity, manifest refraction, spectacle-corrected visual acuity (S-CDVA), steep / flat keratometric values, corneal astigmatism, records of rigid / soft CL fitted before HCL, all parameters of the trial lenses, and the final prescribed HCL parameters and H...
Source: European Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Harbiyeli II, Erdem E, Isik P, Yagmur M, Ersoz R Tags: Eur J Ophthalmol Source Type: research

Reply to Dr I şıl Kutluturk Karagoz letter to the editor.
Reply to Dr Işıl Kutluturk Karagoz letter to the editor. Eur J Ophthalmol. 2020 Jul 14;:1120672120943121 Authors: Hernandez-Da Mota S, Roig Melo-Granados E, Rodriguez-Ayala E PMID: 32664739 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 14, 2020 Category: Opthalmology Authors: Hernandez-Da Mota S, Roig Melo-Granados E, Rodriguez-Ayala E Tags: Eur J Ophthalmol Source Type: research

Endoscopic endonasal balloon-dacryoplasty in failed dacryocystorhinostomy.
CONCLUSION: Our results indicate that trans-nasal balloon-assisted dacryoplasty can be considered as a safe and reliable surgical approach after a failed primary dacryocystorhinostomy. The shorter surgical time and reduced post-operative complication rates are the main advantages of this procedure. PMID: 32664743 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 14, 2020 Category: Opthalmology Authors: Indelicato P, Vinciguerra A, Giordano Resti A, Bussi M, Trimarchi M Tags: Eur J Ophthalmol Source Type: research

Large choroidal excavation in myopic macular degeneration: A case report.
CONCLUSIONS: LCE may be the evolution of FCE in highly myopic eyes, further studies are needed to describe the natural history of choroidal excavations in degenerative myopia. PMID: 32664753 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 14, 2020 Category: Opthalmology Authors: Federico B, Alessandro A, Francesco B, Parodi Maurizio B Tags: Eur J Ophthalmol Source Type: research

The prevalence of keratoconus in children with allergic eye disease in an Egyptian population.
Abstract PURPOSE: To determine the prevalence of keratoconus (KC) among children with ocular allergy. METHODS: A cross-sectional study was conducted on all children presenting with ocular allergic disease from September 2017 to September 2018. All study participants were subjected to history taking (a specially designed questionnaire), routine ophthalmological examination, and corneal tomography. RESULTS: A total of 79% of the study patients had vernal keratoconjunctivitis (VKC) while the remaining had perennial allergic conjunctivitis (10%), seasonal allergic conjunctivitis (9%) and atopic keratoconjunc...
Source: European Journal of Ophthalmology - July 13, 2020 Category: Opthalmology Authors: Ahmed AS, El-Agha MH, Khaled MO, Shousha SM Tags: Eur J Ophthalmol Source Type: research

Corrigendum to "INVICTUS: Intravitreal aNti-VEGF and dexamethasone implant comparison for treatment of diabeTic macUlar edema: 12  months follow-up Study".
Corrigendum to "INVICTUS: Intravitreal aNti-VEGF and dexamethasone implant comparison for treatment of diabeTic macUlar edema: 12 months follow-up Study". Eur J Ophthalmol. 2020 Jul 08;:1120672120942974 Authors: PMID: 32635751 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 8, 2020 Category: Opthalmology Tags: Eur J Ophthalmol Source Type: research

Dexamethasone implants in patients with diabetic macular edema undergoing cataract surgery: Italian expert panel consensus statements.
CONCLUSION: The consensus statements can help provide practical guidance for clinicians in daily practice on the rationale, patient diagnosis and selection, and optimal management of patients with DME undergoing cataract surgery. PMID: 32635762 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - July 8, 2020 Category: Opthalmology Authors: Alessio G, Boscia F, Caporossi A, Panozzo G, Reibaldi M, Staurenghi G, Varano M, Bandello F Tags: Eur J Ophthalmol Source Type: research