Endometriosis is Associated with Higher Healthcare Utilization and Upper Gastrointestinal Symptoms
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - March 19, 2024 Category: Gastroenterology Authors: Madison Simons, Michael Cline, Ashley Gubbels, Cara King, Anthony Lembo, Stephen Lupe Tags: Research Letter Source Type: research
Is the leptin/BMI ratio a reliable biomarker for endometriosis?
ConclusionThe results of present study do not support the relevance of leptin concentration determination as a biomarker of the endometriosis. Due to the limited number of samples in the tested group, further studies are needed to confirm its role. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 19, 2024 Category: Endocrinology Source Type: research
World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: V. physical examination standards in endometriosis research
The World Endometriosis Research Foundation (WERF) established the Endometriosis Phenome and Biobanking Harmonisation Project (EPHect) to create standardized documentation tools (with common data elements) to facilitate the comparison and combination of data across different research sites and studies. In 2014, four data research standards were published: clinician-reported surgical data, patient-reported clinical data, and fluid and tissue biospecimen collection. Our current objective is to create an EPHect standard for the clinician-reported physical examination (EPHect-PE) for research studies. (Source: Fertility and Sterility)
Source: Fertility and Sterility - March 18, 2024 Category: Reproduction Medicine Authors: Tinya Lin, Catherine Allaire, Sawsan As-Sanie, Pamela Stratton, Katy Vincent, G. David Adamson, Lars Arendt-Nielsen, Deborah Bush, Femke Jansen, Jennifer Longpre, Luk Rombauts, Jay Shah, Abeesha Toussaint, Lone Hummelshoj, Stacy A. Missmer, Paul J. Yong, Tags: Endometriosis Source Type: research
Risk factors associated with changes in serum anti-M üllerian hormone levels before and after laparoscopic cystectomy for endometrioma
ConclusionLaparoscopic removal of endometriomas can adversely affect ovarian reserve, especially during bilateral cysts removal and when patients are diagnosed as having a higher stage of endometriosis, further impacting ovarian function. It should be noted that a decrease in AMH levels may not necessarily indicate an absolute decline in fertility. Therefore, it is crucial to conduct thorough patient evaluations and provide comprehensive patient education to offer appropriate guidance for fertility preservation. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 18, 2024 Category: Endocrinology Source Type: research
Human epididymis protein 4: Analysis of national health and nutrition examination survey data
The average risk of developing ovarian cancer in the United States is 1 in 78, with the majority of women diagnosed with advanced stage disease (stage III/IV) [1,2]. The benefits and risks associated with screening average-risk women have been studied to include serum blood draws or use of transvaginal ultrasound [3]. Cancer Antigen 125 (CA 125) has low sensitivity in early stages of ovarian cancer, and elevations are also seen in other conditions such as endometriosis or inflammatory conditions of the peritoneum [4,5]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 17, 2024 Category: OBGYN Authors: Emily R. Penick, Thomas A. Beltran, Y. Sammy Choi, Karen L. Wilson Tags: Full length article Source Type: research
Gorgon sign in abdominal wall endometriosis
Graphical abstract (Source: Abdominal Imaging)
Source: Abdominal Imaging - March 16, 2024 Category: Radiology Source Type: research
Microplastics in human urine: Characterisation using μFTIR and sampling challenges using healthy donors and endometriosis participants
The objective herein was to undertake an analysis of MP contamination in human urine samples, from healthy individuals and participants with endometriosis, with respect to their presence, levels, and the characteristics of any particles identified. A total of 38 human urine samples and 15 procedural blanks were analysed. MPs were characterised using μFTIR spectroscopy (size limitation of 5 μm) and SEM-EDX. In total, 123 MP particles consisting of 22 MP polymer types were identified within 17/29 of the healthy donor (10 mL) urine samples, compared with 232 MP particles of differing 16 MP polymer types in 12/19 urine sampl...
Source: Ecotoxicology and Environmental Safety - March 15, 2024 Category: Environmental Health Authors: Jeanette M Rotchell Chloe Austin Emma Chapman Charlotte A Atherall Catriona R Liddle Timothy S Dunstan Ben Blackburn Andrew Mead Kate Filart Ellie Beeby Keith Cunningham Jane Allen Hannah Draper Barbara-Ann Guinn Source Type: research
High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia
Immune dysfunction is one of the central components in the development and progression of endometriosis by establishing a chronic inflammatory environment. Western-style high-fat diets (HFD) have been linked to greater systemic inflammation to cause metabolic and chronic inflammatory diseases, and are also considered an environmental risk factor for gynecologic diseases. Here, we aimed to examine how HFD cause an inflammatory environment in endometriosis and discern their contribution to endometriotic-associated hyperalgesia. Our results showed that HFD-induced obesity enhanced abdominal hyperalgesia that was induced by en...
Source: Frontiers in Endocrinology - March 15, 2024 Category: Endocrinology Source Type: research
Robot-assisted vaginal Natural Orifice Transluminal Endoscopic Surgery (RvNOTES) with total hysterectomy for management of stage IV endometriosis with/without complete cul-de-sac obliteration: 23-case pilot feasibility study
To show feasibility and short-term outcomes of Robot-assisted vaginal NOTES (RvNOTES) for the treatment of stage IV endometriosis during total hysterectomy with/without complete cul-de-sac obliteration. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - March 15, 2024 Category: OBGYN Authors: Gufeng Xu, Daniel Y Lovell, Xiaoming Guan Tags: Original Article Source Type: research
Vaginoscopic resection of hemivagina, in a 20 ‐year‐old virgin female with prior misdiagnosis of OHVIRA syndrome as a bicornuate uterus: A case report
This study presents a 20-year-old virgin female who was diagnosed with OHVIRA syndrome and treated by vaginoscopy using the hymen preservation technique. Also, she was misdiagnosed with non-communicating rudimentary uterine horn 4 years ago. Late or misdiagnosis of OHVIRA syndrome can affect fertility and pregnancy outcomes. Therefore, early diagnosis and management are crucial. OHVIRA syndrome's misdiagnosis is possible with other Mullerian duct anomalies, such as a rudimentary uterine horn. Also, patients with misdiagnos is undergo unnecessary interventions. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Ameneh Haghgoo,
Ali Faegh,
Saeed Nasiri,
Farnaz Akhbari Tags: CASE REPORT Source Type: research
Laparoscopically confirmed endometriosis and anti-M üllerian hormone levels: Findings from the Nurses' Health Study II
Anti-m üllerian hormone (AMH) is secreted by granulosa cells in the ovaries in proportion to the number of developing follicles [1]. As a woman ages, her AMH steadily declines which mirrors the decline in the number of available oocytes for ovulation [2]. While AMH does not predict pregnancy success in wo men trying to conceive, it is associated with oocyte yield, infertility diagnoses, and time to menopause. AMH has become a commonly used proxy for clinically monitoring declines in ovarian function [2,3]. (Source: Maturitas)
Source: Maturitas - March 14, 2024 Category: Primary Care Authors: Leslie V. Farland, Michelle Valenti, William J. Degnan, Elizabeth R. Bertone-Johnson, Holly R. Harris, Amy D. DiVasta, Kathryn M. Rexrode, A. Heather Eliassen, Stacey A. Missmer Tags: Original article Source Type: research
MiRNAs related in signaling pathways of women's reproductive diseases: an overview
CONCLUSIONS: This review focuses on the investigation of miRNAs and their involvement in various reproductive disorders in women, including their molecular targets. Additionally, it explores the role of miRNAs in the development and progression of these disorders.PMID:38472662 | DOI:10.1007/s11033-024-09357-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 13, 2024 Category: Molecular Biology Authors: Malihe Bagheri Behzad Khansarinejad Mahdieh Mondanizadeh Mohadeseh Azimi Shima Alavi Source Type: research
