MiRNAs related in signaling pathways of women's reproductive diseases: an overview
CONCLUSIONS: This review focuses on the investigation of miRNAs and their involvement in various reproductive disorders in women, including their molecular targets. Additionally, it explores the role of miRNAs in the development and progression of these disorders.PMID:38472662 | DOI:10.1007/s11033-024-09357-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 13, 2024 Category: Molecular Biology Authors: Malihe Bagheri Behzad Khansarinejad Mahdieh Mondanizadeh Mohadeseh Azimi Shima Alavi Source Type: research
Self-compassion and health-related quality of life in individuals with endometriosis
. (Source: Psychology and Health)
Source: Psychology and Health - March 13, 2024 Category: Psychiatry & Psychology Authors: Chelsea M. SkinnerRoeline G. KuijerSchool of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand Source Type: research
Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway
CONCLUSIONS: IGFBP1 mediates aberrant stromal-epithelial communication in endometriosis. Metformin can upregulate IGFBP1 expression in EcSCs by activating AMPK, and upregulated IGFBP1 enhances the inhibition of epithelial cell proliferation. IGFBP1 is expected to be a therapeutic target for endometriosis.PMID:38466134 | DOI:10.1080/01443615.2024.2321651 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - March 11, 2024 Category: OBGYN Authors: Xuping Shao Changling Li Junhui Liang Li Changzhong Source Type: research
The Dysregulated IL-23/TH17 Axis in Endometriosis Pathophysiology
J Immunol. 2024 Mar 11:ji2400018. doi: 10.4049/jimmunol.2400018. Online ahead of print.ABSTRACTEndometriosis is a chronic inflammatory disease in which endometrial-like tissue grows ectopically, resulting in pelvic pain and infertility. IL-23 is a key contributor in the development and differentiation of TH17 cells, driving TH17 cells toward a pathogenic profile. In a variety of inflammatory and autoimmune disorders, TH17 cells secrete proinflammatory cytokines, including IL-17, contributing to disease pathophysiology. Our studies and others have implicated IL-17 and TH17 cell dysregulation in endometriosis, which is assoc...
Source: Journal of Immunology - March 11, 2024 Category: Allergy & Immunology Authors: Danielle J Sisnett Katherine B Zutautas Jessica E Miller Harshavardhan Lingegowda Soo Hyun Ahn Alison McCallion Olga Bougie Bruce A Lessey Chandrakant Tayade Source Type: research
Women in minimally invasive gynecological surgery and endometriosis challenges and overcoming
Women Health. 2024 Mar;64(3):199-201. doi: 10.1080/03630242.2024.2320960. Epub 2024 Mar 10.NO ABSTRACTPMID:38462676 | DOI:10.1080/03630242.2024.2320960 (Source: Women and Health)
Source: Women and Health - March 11, 2024 Category: Primary Care Authors: Helizabet Salom ão Abdalla Ayroza Ribeiro Source Type: research
