Lateral closure of the uterine artery prior to laparoscopic hysterectomy: a systematic review
J Obstet Gynaecol. 2021 Oct 23:1-8. doi: 10.1080/01443615.2021.1968810. Online ahead of print.ABSTRACTAn alternative surgical technique with closure of the uterine artery at its origin, known as lateral approach prior to TLH, has been proposed and it may offer important benefits to both patients and surgeons. Our objectives were to review the current literature regarding surgical outcomes between lateral and conventional approach in relation to TLH. We followed the 'PRISMA' guidelines and conducted a systematic review, which involved searching PubMed and Embase databases for RCTs evaluating the topic. We identified four RC...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Vibeke Kramer Lysdal Grigorios Karampas Martin Rudnicki Source Type: research

Parental germline mosaic transmission of 5p13.2 microduplication in two siblings of a Chinese family
J Obstet Gynaecol. 2021 Oct 23:1-3. doi: 10.1080/01443615.2021.1959532. Online ahead of print.NO ABSTRACTPMID:34689684 | DOI:10.1080/01443615.2021.1959532 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Qi Tian Li-Li Xu Dong-Zhi Li Source Type: research

Re-intervention and patient satisfaction rates following office radiofrequency endometrial ablation: a comparative retrospective study of 408 cases
This study showed lower surgical re-intervention rate than previously reported in observational studies, and high rates of long-term women satisfaction. The outcomes were similar in office and day-case settings.Impact statementWhat is already known on this subject? Previous studies have shown the safety and effectiveness of radiofrequency endometrial ablation for treating heavy periods. However, studies investigating it, outside clinical trials, either included a small sample size, a short-term follow-up, poor reporting so that it is impossible to judge whether some women underwent re-intervention in another centre, failed...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Ahmed Ghoubara Seuvandhi Gunasekera Lavanya Rao Ayman Ewies Source Type: research

Non-alcoholic fatty liver disease in polycystic ovarian syndrome in Indian women
J Obstet Gynaecol. 2021 Oct 23:1-5. doi: 10.1080/01443615.2021.1969346. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is a frequent occurrence in polycystic ovarian syndrome (PCOS). We studied the frequencies and characteristics of NAFLD in PCOS women. We compared various methods of detection of advanced fibrosis/cirrhosis. One hundred and forty women with PCOS and seventy controls, matched for age, were evaluated for the presence of NAFLD. Anthropometric variables, serum levels of aminotransferases, glucose, lipids and transient elastography were done. Thirty-six percent of the NAFLD patients had...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Sujata Siwatch Virendra Singh Lakhbir K Dhaliwal Sunita Kumari Kartar Singh Source Type: research

Asymptomatic microperforated transverse vaginal septum
J Obstet Gynaecol. 2021 Oct 23:1-3. doi: 10.1080/01443615.2021.1967304. Online ahead of print.NO ABSTRACTPMID:34689698 | DOI:10.1080/01443615.2021.1967304 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Marilia Freixo Elisa Soares Maria Liz Coelho Ana Rita Pinto Cristina Oliveira Source Type: research

Subcutaneous irrigation with rifampicin < em > vs. < /em > povidone-iodine for the prevention of incisional surgical site infections following caesarean section: a prospective, randomised, controlled trial
This study may contribute to reaching a sufficient level of evidence on surgical wound infections after caesarean sections, which are still missing in the literature, and that may be guiding for the studies that will be conducted on this subject in the future.PMID:34689702 | DOI:10.1080/01443615.2021.1964453 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Özge Kömürcü Karuserci Seyhun Sucu Source Type: research

Idiopathic polyhydramnios and foetal macrosomia in the absence of maternal diabetes: clinical vigilance for costello syndrome
J Obstet Gynaecol. 2021 Oct 23:1-3. doi: 10.1080/01443615.2021.1959533. Online ahead of print.NO ABSTRACTPMID:34689704 | DOI:10.1080/01443615.2021.1959533 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Liu-Bing Lan Dong-Zhi Li Source Type: research

The role of gut microbiome in prevention, diagnosis and treatment of gestational diabetes mellitus
J Obstet Gynaecol. 2021 Oct 25:1-7. doi: 10.1080/01443615.2021.1959534. Online ahead of print.ABSTRACTGestational diabetes mellitus (GDM) is a common metabolic disease associated with maternal and foetal complications; gut microbiome might participate in GDM pathogenesis. Possible biological links include short chain fatty acids, incretin hormones, bile acids homeostasis and peroxisome proliferator-activated receptor gamma deficiency. Gut microbiome differs in patients with GDM even in early pregnancy, but no differences are observed five years postpartum. Patients have enriched Verrucomicrobia phylum, Christensenellaceae ...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Ermioni Tsarna Panagiotis Christopoulos Source Type: research

Can pregnancy aggravate the criticality of COVID-19 infection in obese asthmatic peripartum woman? A peripartum COVID-19 mortality case report
J Obstet Gynaecol. 2021 Oct 25:1-3. doi: 10.1080/01443615.2021.1960290. Online ahead of print.ABSTRACTAs coronavirus disease 2019 (COVID-19) sweeps all over the world, Information about COVID-19 is evolving rapidly and interim guidance by multiple organisations is constantly being updated and expanded. Early with discovery of COVID 19, it was reported that pregnancy did affect the progress of the disease severity. Recently, Centres for Disease Control and Prevention (CDC) reported that pregnancy is a risk factors for COVID-19 severity. The current case report is presenting a peripartum COVID-19 positive mortality case.PMID...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Mohamed Fouad Selim Sherif A A Mohamed Manal Mohamed Ali Abdou Mohamed Salah Haggag Yasser Gamal Azza S Abd Elhaffez Source Type: research

Do techniques of surgical management of ovarian endometrioma affect ovarian reserve? A narrative review
J Obstet Gynaecol. 2021 Oct 25:1-7. doi: 10.1080/01443615.2021.1962817. Online ahead of print.ABSTRACTEndometriotic ovarian cysts are one of the more common gynecological disorders found in reproductive-aged and infertile women. The aim of this review is to summarise information regarding the effect of surgical treatment of endometrioma on ovarian reserve. In women with endometrioma ovarian reserve is decreased compared to similarly aged healthy women and surgical management techniques cause an additional reduction. Evidence suggests that laparoscopic ovarian cystectomy via stripping is the preferable surgical technique fo...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Konstantinos Samartzis Nikolaos Kathopoulis Dimitris Loutradis Athanasios Protopapas Source Type: research

Association between single nucleotide polymorphisms of < em > VEGF < /em > gene and pelvic lymph node metastasis in patients with early-stage cervical cancer
J Obstet Gynaecol. 2021 Oct 25:1-5. doi: 10.1080/01443615.2021.1963691. Online ahead of print.ABSTRACTCervical cancer patients in early-stage cervical cancer (ECC) were divided into pelvic lymph node (PLN) metastasis and non-PLN metastasis group. Single nucleotide polymorphism (SNP) genotyping for the VEGF gene was conducted and plasma VEGF levels were measured. Multivariate analysis was performed to assess the correlation between SNPs of the VEGF gene and PLN metastasis. We found that SNP of the VEGF rs2010963 was independently associated with PLN metastasis. GG and CG genotype had increased susceptibility to PLN metastas...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Wei Zhong Xingyan Guo Yan He Maimaiti Yasen Maimaitimin Adilai Hailiqiemu Abudubari Abuduhelili Abudukadier Xiafukaiti Alifu Source Type: research

Relationship between second-trimester amniotic fluid and plasma levels of angiopoietin-2 and thrombomodulin with adverse pregnancy outcome
J Obstet Gynaecol. 2021 Oct 25:1-6. doi: 10.1080/01443615.2021.1960293. Online ahead of print.ABSTRACTOur objective is to investigate maternal midtrimester plasma and amniotic fluid (AF) levels of angiopoietin-2 (Ang-2) and thrombomodulin (TM), which are involved in vascular remodelling and endothelium activation, in placental disorders including foetal growth restriction (FGR) and preeclampsia (PE). This prospective multiparametric pilot study was conducted at the Perinatology Division of Trakya University in a population undergoing genetic amniocentesis. Both AF and plasma aliquots were kept in -80 °C until ELISA ass...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Cem Yener F üsun Varol Cihan Inan Havva S ütcü Sinan Ate ş Cenk Sayin Source Type: research

Nausea and vomiting during pregnancy: a possible correlation with obsessive compulsive disorder and alexithymia
J Obstet Gynaecol. 2021 Oct 25:1-6. doi: 10.1080/01443615.2021.1960492. Online ahead of print.ABSTRACTThe possible correlation between nausea and vomiting during pregnancy (NVP) with obsessive-compulsive disorder (OCD) and alexithymia were examined in this cross-sectional study. A cohort of pregnant women at the first trimester of pregnancy experiencing NVP were divided into three groups, according to severity (mild, moderate and severe) with the Pregnancy Unique Quantification of Emesis and Nausea (PUQE) test. The Maudsley Obsessive Compulsive Disorder Scale (MOCQ) and the Toronto Alexithymia Scale (TAS-20) were applied. ...
Source: Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: Banuhan Şahin Serap Özçetinkaya Erdoğan Gizem Cura Şahin Pervin Karl ı Osman Fad ıl Kara Şafak Hatırnaz Andrea Tinelli Source Type: research

Pipelle endometrial sampling success rates in Kazakhstani settings: results from a prospective cohort analysis
J Obstet Gynaecol. 2021 Sep 30:1-6. doi: 10.1080/01443615.2021.1953452. Online ahead of print.ABSTRACTThe aim of this study was to evaluate the feasibility of Pipelle endometrial sampling and to explore factors influencing Pipelle success rate in the clinical settings of Kazakhstan. This prospective analysis included 87 patients who had undergone Pipelle biopsy due to medical indications for endometrial sampling. We analysed physician and patient-related factors potentially influencing the success rate of this method. Pipelle endometrial biopsy overall success rate was 82.76%. The indications for the procedure and patients...
Source: Journal of Obstetrics and Gynaecology - October 1, 2021 Category: OBGYN Authors: Milan Terzic Gulzhanat Aimagambetova Gauri Bapayeva Talshyn Ukybassova Kamila Kenbayeva Aiym Kaiyrlykyzy Bakytkali Ibrayimov Alla Lyasova Sanja Terzic Ibrahim Alkatout Georgios Gitas İsmet Hortu Simone Garzon Antonio Simone Lagan à Source Type: research

Paternal body mass index before conception associated with offspring's birth weight in Chinese population: a prospective study
This study evaluated the relationship between preconception paternal body weight and their offspring's birth weight in 1,810 Chinese mother-father-baby trios. Information on paternal and maternal preconception body weight and height was collected via a self-reported questionnaire. Birth weight was collected from medical records. Paternal preconception body weight was associated with offspring's birth weight (p trend = .02) after multivariate adjustment. Each standard deviation increment of paternal body mass index was associated with an additional 29.6 g increase of birth weight (95% confident interval: 5.7 g, 53.5 g). The...
Source: Journal of Obstetrics and Gynaecology - September 30, 2021 Category: OBGYN Authors: Renying Xu Weixiu Zhao Tao Tan Haojie Li Yanping Wan Source Type: research

Reproductive outcomes after laparoscopic surgery in infertile women affected by ovarian endometriomas, with or without < em > in  vitro < /em > fertilisation: results from the SAFE (surgery and ART for endometriomas) trial
J Obstet Gynaecol. 2021 Sep 29:1-7. doi: 10.1080/01443615.2021.1959536. Online ahead of print.ABSTRACTWe performed a retrospective cohort study, namely "Surgery and ART for Endometriomas" (SAFE) trial (Clinical Trial ID: NCT03717870), including women who underwent laparoscopic cystectomy for endometrioma before first IVF and compared their reproductive outcomes with the ones of women without endometriosis and with unexplained infertility, tubal factor or male factor infertility. We found that women who underwent previous laparoscopic cystectomy for endometrioma had higher FSH and LH levels between the 2nd and 5th...
Source: Journal of Obstetrics and Gynaecology - September 29, 2021 Category: OBGYN Authors: Helena Ban Frange ž Eda Vrtacnik Bokal Martin Štimpfel Teja Divjak Budihna Ferdinando Antonio Gulino Simone Garzon Fabio Ghezzi Ibrahim Alkatout Georgios Gitas Antonio Simone Lagan à Source Type: research

Foetal thoracic hypoplasia: concomitant anomalies and neonatal outcomes
In this study, most of the cases have additional anomalies, especially skeletal system and head-face anomalies. Approximately half of the newborns with thoracic hypoplasia die within the first 24 h.What are the implications of these findings for clinical practice and/or further research? When we need to consult a family considering the outcome of thoracic hypoplasia, this study can be guiding and helpful. On the other hand, the effects of additional anomalies on the prognosis of foetal and neonatal period are not clear. More studies are needed to better understand the prognosis of thoracic hypoplasias.PMID:34579606 | DOI:1...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Munip Akalin Oya Demirci Guher Bolat Ozge Kahramanoglu Mucize Eric Ozdemir Ali Karaman Source Type: research

Efficacy of spontaneous pushing with pursed lips breathing compared with directed pushing in maternal and neonatal outcomes
J Obstet Gynaecol. 2021 Sep 28:1-7. doi: 10.1080/01443615.2021.1945016. Online ahead of print.ABSTRACTThis is a quasi-randomised clinical trial, with 62 low-risk pregnant women in the second stage of labour. They were randomly allocated in control (CG) (n = 31) and intervention (IG) (n = 31) groups. The IG performed spontaneous pushing with pursed lips breathing while the CG was oriented to perform directed pushing associated with Valsalva Manoeuvre (VM). There was no difference between the groups regarding the occurrence of episiotomy (RR 1,1; 95%IC 1,0 to 1,2). However, there was a decrease in the duration of the materna...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Ana Eulina Ara újo Alexandre Delgado Juliana Netto Maia Shirley Lima Campos Caroline Wanderley Souto Ferreira Andrea Lemos Source Type: research

The effect of carbamazepine, which increases oestrogen destruction, on the endometriotic implants; an experimental rat model
J Obstet Gynaecol. 2021 Sep 28:1-7. doi: 10.1080/01443615.2021.1953453. Online ahead of print.ABSTRACTWe planned this experimental study to investigate the effect of carbamazepine (CMZ) on the endometriotic implants. Rats were randomised into four groups after endometriosis surgery. Drinking water was given to the sham group, 0.2 mg/kg oestradiol valerate (EV) to the EV group, 100 mg/kg/day CMZ to the CMZ group, and 0.2 mg/kg EV and 100 mg/kg/day CMZ to the EV-CMZ group. The endometrium of the rats using CMZ stained more intensely with cytochrome P450-3A4 (CYP3A4) enzyme. No endometrial hyperplasia was found in these rats....
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Mehmet Bulbul Mehmet Can Nacar Bilge Aydin Turk Talip Karacor Muhittin Onderci Ali Parlar P ınar Kirici Cihat Ucar Source Type: research

Cross-sectional study on the impact of age, menopause and quality of life on female sexual function
In conclusion, the prevalence of FSD in our population was 51.6%. Our study results reveal that a reduction in FSFI scores has a negative impact on QoL and vice versa, regardless of the reason for consultation. Elderly age and postmenopausal state have deleterious effects on FSF.Impact statementWhat is already known on this subject? Poor QoL can adversely affect FSF and vice versa. The study of FSF is relatively recent and there is controversy regarding the deleterious effects of elderly age and menopause on FSF. The prevalence of FSD is difficult to precisely determine, given the studies' use of different definitions for ...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Jorge Cea Garc ía Francisco M árquez Maraver M Carmen Rubio Rodr íguez Source Type: research

Practice changes in Italian Gynaecologic Units during the COVID-19 pandemic: a survey study
J Obstet Gynaecol. 2021 Sep 28:1-8. doi: 10.1080/01443615.2021.1954149. Online ahead of print.ABSTRACTThe impact of Coronavirus disease 2019 pandemic on Italian Gynaecological Units practice and the compliance and satisfaction with available guidelines/recommendations is unknown. Therefore, a survey was conducted among all Italian Gynaecological Units Directors in April 2020. The response rate was 90% (135/150). 77.8% of centres performed surgery only for oncologic or not deferrable pathologies, and 9.6% was closed. 68.7% of directors were at least moderately satisfied by published guidelines/recommendations, but 94.8% of ...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Stefano Uccella Simone Garzon Gabriele Lanzo Antonella Cromi Pier Carlo Zorzato Jvan Casarin Mariachiara Bosco Irene Porcari Francesca Ciccarone Mario Malzoni Fabio Ghezzi Giovanni Scambia Massimo Franchi Source Type: research

The effect of dydrogesterone on sexual function in endometriosis
J Obstet Gynaecol. 2021 Sep 28:1-4. doi: 10.1080/01443615.2021.1958765. Online ahead of print.ABSTRACTEndometriosis is an oestrogen-dependent chronic disease, which is commonly regarded as a disease of reproductive-aged women. We aimed to evaluate the sexual function with Female Sexual Function Index (FSFI) in women with endometriosis who received dydrogesterone for 6 months. A total of 79 women with endometriomas were recruited in the study group and received 10 mg dydrogesterone tablets orally for 6 months. FSFI and visual analog scale (VAS) scores for each patient before and after treatment were recorded. When before tr...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: P ınar Yalçın Bahat Burak Y ücel Bahar Yuksel Ozgor P ınar Kadiroğulları Nura Fitnat Topbas Sel çuki K übra Çakmak Eda Üreyen Özdemir Source Type: research

Foetal thoracic hypoplasia: concomitant anomalies and neonatal outcomes
In this study, most of the cases have additional anomalies, especially skeletal system and head-face anomalies. Approximately half of the newborns with thoracic hypoplasia die within the first 24 h.What are the implications of these findings for clinical practice and/or further research? When we need to consult a family considering the outcome of thoracic hypoplasia, this study can be guiding and helpful. On the other hand, the effects of additional anomalies on the prognosis of foetal and neonatal period are not clear. More studies are needed to better understand the prognosis of thoracic hypoplasias.PMID:34579606 | DOI:1...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Munip Akalin Oya Demirci Guher Bolat Ozge Kahramanoglu Mucize Eric Ozdemir Ali Karaman Source Type: research

Efficacy of spontaneous pushing with pursed lips breathing compared with directed pushing in maternal and neonatal outcomes
J Obstet Gynaecol. 2021 Sep 28:1-7. doi: 10.1080/01443615.2021.1945016. Online ahead of print.ABSTRACTThis is a quasi-randomised clinical trial, with 62 low-risk pregnant women in the second stage of labour. They were randomly allocated in control (CG) (n = 31) and intervention (IG) (n = 31) groups. The IG performed spontaneous pushing with pursed lips breathing while the CG was oriented to perform directed pushing associated with Valsalva Manoeuvre (VM). There was no difference between the groups regarding the occurrence of episiotomy (RR 1,1; 95%IC 1,0 to 1,2). However, there was a decrease in the duration of the materna...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Ana Eulina Ara újo Alexandre Delgado Juliana Netto Maia Shirley Lima Campos Caroline Wanderley Souto Ferreira Andrea Lemos Source Type: research

The effect of carbamazepine, which increases oestrogen destruction, on the endometriotic implants; an experimental rat model
J Obstet Gynaecol. 2021 Sep 28:1-7. doi: 10.1080/01443615.2021.1953453. Online ahead of print.ABSTRACTWe planned this experimental study to investigate the effect of carbamazepine (CMZ) on the endometriotic implants. Rats were randomised into four groups after endometriosis surgery. Drinking water was given to the sham group, 0.2 mg/kg oestradiol valerate (EV) to the EV group, 100 mg/kg/day CMZ to the CMZ group, and 0.2 mg/kg EV and 100 mg/kg/day CMZ to the EV-CMZ group. The endometrium of the rats using CMZ stained more intensely with cytochrome P450-3A4 (CYP3A4) enzyme. No endometrial hyperplasia was found in these rats....
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Mehmet Bulbul Mehmet Can Nacar Bilge Aydin Turk Talip Karacor Muhittin Onderci Ali Parlar P ınar Kirici Cihat Ucar Source Type: research

Cross-sectional study on the impact of age, menopause and quality of life on female sexual function
In conclusion, the prevalence of FSD in our population was 51.6%. Our study results reveal that a reduction in FSFI scores has a negative impact on QoL and vice versa, regardless of the reason for consultation. Elderly age and postmenopausal state have deleterious effects on FSF.Impact statementWhat is already known on this subject? Poor QoL can adversely affect FSF and vice versa. The study of FSF is relatively recent and there is controversy regarding the deleterious effects of elderly age and menopause on FSF. The prevalence of FSD is difficult to precisely determine, given the studies' use of different definitions for ...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Jorge Cea Garc ía Francisco M árquez Maraver M Carmen Rubio Rodr íguez Source Type: research

Practice changes in Italian Gynaecologic Units during the COVID-19 pandemic: a survey study
J Obstet Gynaecol. 2021 Sep 28:1-8. doi: 10.1080/01443615.2021.1954149. Online ahead of print.ABSTRACTThe impact of Coronavirus disease 2019 pandemic on Italian Gynaecological Units practice and the compliance and satisfaction with available guidelines/recommendations is unknown. Therefore, a survey was conducted among all Italian Gynaecological Units Directors in April 2020. The response rate was 90% (135/150). 77.8% of centres performed surgery only for oncologic or not deferrable pathologies, and 9.6% was closed. 68.7% of directors were at least moderately satisfied by published guidelines/recommendations, but 94.8% of ...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: Stefano Uccella Simone Garzon Gabriele Lanzo Antonella Cromi Pier Carlo Zorzato Jvan Casarin Mariachiara Bosco Irene Porcari Francesca Ciccarone Mario Malzoni Fabio Ghezzi Giovanni Scambia Massimo Franchi Source Type: research

The effect of dydrogesterone on sexual function in endometriosis
J Obstet Gynaecol. 2021 Sep 28:1-4. doi: 10.1080/01443615.2021.1958765. Online ahead of print.ABSTRACTEndometriosis is an oestrogen-dependent chronic disease, which is commonly regarded as a disease of reproductive-aged women. We aimed to evaluate the sexual function with Female Sexual Function Index (FSFI) in women with endometriosis who received dydrogesterone for 6 months. A total of 79 women with endometriomas were recruited in the study group and received 10 mg dydrogesterone tablets orally for 6 months. FSFI and visual analog scale (VAS) scores for each patient before and after treatment were recorded. When before tr...
Source: Journal of Obstetrics and Gynaecology - September 28, 2021 Category: OBGYN Authors: P ınar Yalçın Bahat Burak Y ücel Bahar Yuksel Ozgor P ınar Kadiroğulları Nura Fitnat Topbas Sel çuki K übra Çakmak Eda Üreyen Özdemir Source Type: research

Evaluation of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in pregnant women with systemic lupus erythematosus
This study is the first to evaluate the possible role of NLR and PLR in pregnant SLE patients in the literature. Further studies are warranted for an elaborate evaluation of NLR and PLR in lupus pregnancies.Impact StatementWhat is already known on this subject? Pregnancy in the setting of SLE is associated with a higher risk of complications. Active disease increases the risk of adverse outcomes further.What the results of this study add? This study is the first to evaluate NLR and PLR in pregnancies complicated by SLE. No significant association between the course of the disease in pregnancy and NLR/PLR was documented.Wha...
Source: Journal of Obstetrics and Gynaecology - September 27, 2021 Category: OBGYN Authors: Huseyin Ekici Metehan Imamoglu Firat Okmen Gizem Gencosman Gunes Ak Mete Ergenoglu Source Type: research

Squamous cell carcinoma antigen combined with HPV-16 infection in predicting high-grade squamous intraepithelial lesions of the cervix
In this study, 541 patients collected in Sun Yat-Sen hospital from January 2007 to December 2016 were selected. HPV genotype detection and SCC-ag detection were done in these patients. It was found that when serum SCC-ag level exceeded over 0.39 ng/ml in HPV-16 positive patients, the sensitivity and specificity of this novel approach to predict high-grade cervical intraepithelial neoplasia could reach to 83.1% and 62.1%, respectively. The result suggested that the combination of serum SCC-ag level and HPV-16 infection could be used as a novel approach for high-grade cervical intraepithelial neoplasia screening.Impact state...
Source: Journal of Obstetrics and Gynaecology - September 27, 2021 Category: OBGYN Authors: Guanglei Zhong Yuhan Wang Shixian Yao Xingyu Fang Rongchun Lin Zhongqiu Lin Yongpai Peng Tingting Yao Source Type: research

The efficacy and safety of second dinoprostone pessary or balloon catheter after unsuccessful primary ripening with dinoprostone pessary
J Obstet Gynaecol. 2021 Sep 25:1-5. doi: 10.1080/01443615.2021.1948510. Online ahead of print.ABSTRACTWe investigated which treatment should be applied if primary cervical ripening with a dinoprostone pessary is unsuccessful. We included 281 women who experienced unsuccessful cervical ripening with a dinoprostone pessary and continued on induction of labour (IOL). Of the 281 women recruited, 177 were given a second dose of dinoprostone; 104 women received a balloon catheter. The second dinoprostone pessary was successful in achieving vaginal delivery in 88 of the 177 (48.6%) women, while the balloon catheter was successful...
Source: Journal of Obstetrics and Gynaecology - September 27, 2021 Category: OBGYN Authors: Dongli Sun Qiaoai Wu Xinfan Wang Fengmei Wang Source Type: research

Dual trigger with the combination of gonadotropin-releasing hormone agonist and standard dose of human chorionic gonadotropin improves < em > in  vitro < /em > fertilisation outcomes in poor ovarian responders
J Obstet Gynaecol. 2021 Sep 25:1-6. doi: 10.1080/01443615.2021.1945560. Online ahead of print.ABSTRACTThe study aimed to evaluate the impact of the dual trigger with the combination of GnRH agonist and standard dose of recombinant hCG on IVF outcomes in poor ovarian responders with GnRH antagonist protocol. 1283 cycles of 1010 poor responder patients according to Bologna criteria were retrospectively analysed in terms of final oocyte maturation: dual trigger group (250 μg hCG + 0.2 mg triptorelin) or standard group (250 μg hCG). Primary outcome measures were the number of retrieved and mature oocytes. The secondary o...
Source: Journal of Obstetrics and Gynaecology - September 27, 2021 Category: OBGYN Authors: Ilknur Mutlu Erhan Demirdag Funda Cevher Ahmet Erdem Mehmet Erdem Source Type: research