Peer health coach experiences promoting a nondiet approach in a university health coaching program
Peer health coach experiences promoting a nondiet approach in a university health coaching program Saemi Lee, Janaina Lima Fogaca, Natalie Papini, Courtney Joseph, Nikole Squires, Dawn Clifford, Jonathan Lee Health Education, Vol. ahead-of-print, No. ahead-of-print, pp.- Research shows peer health education programs on university campuses can support students in pursuing sustainable health-related behavior changes. However, few programs deliver peer health education through a nondiet, weight-inclusive framework. Research shows that health educators who challenge the status quo of diet culture and weight-focused health in...
Source: Health Education - May 6, 2024 Category: International Medicine & Public Health Authors: Saemi Lee Janaina Lima Fogaca Natalie Papini Courtney Joseph Nikole Squires Dawn Clifford Jonathan Lee Source Type: research
Exploring Putative Causal Associations between Diet and Periodontal Disease Susceptibility
CONCLUSIONS: The findings suggest potential protective effects of higher fruit and water intake against gingivitis and other periodontal problems, while alcohol and processed meat intake may increase the risks of periodontal disease. Our study provides preliminary causal evidence on the effects of diet on periodontal health and could inform prevention strategies targeting dietary habits to improve oral health.KNOWLEDGE TRANSFER STATEMENT: This study suggests that fruit and water intake may protect against periodontal disease, while alcohol and processed meats increase risk, informing dietary guidelines to improve oral heal...
Source: Cell Research - May 6, 2024 Category: Cytology Authors: X X Ying Y Hou X Zheng J X Ma M L Wu M Liu X Y Liu K L Zhang Source Type: research
Acetoacetate and D- and L- β-hydroxybutyrate have distinct effects on basal and insulin-stimulated glucose uptake in L6 skeletal muscle cells
Am J Physiol Cell Physiol. 2024 May 6. doi: 10.1152/ajpcell.00718.2023. Online ahead of print.ABSTRACTKetone bodies (acetoacetate and β-hydroxybutyrate) are oxidized in skeletal muscle mainly during fasting as an alternative source of energy to glucose. Prior studies suggest that there is a negative relationship between increased muscle ketolysis and muscle glucose metabolism in mice with obesity and/or type 2 diabetes. Therefore, we investigated the connection between increased ketone body exposure and muscle glucose metabolism by measuring the effect of a 3-hour exposure to ketone bodies on glucose uptake in differentia...
Source: Am J Physiol Cell Ph... - May 6, 2024 Category: Cytology Authors: Hannah Khouri Mathilde Roberge John R Ussher C éline Aguer Source Type: research
Acetoacetate and D- and L- β-hydroxybutyrate have distinct effects on basal and insulin-stimulated glucose uptake in L6 skeletal muscle cells
Am J Physiol Cell Physiol. 2024 May 6. doi: 10.1152/ajpcell.00718.2023. Online ahead of print.ABSTRACTKetone bodies (acetoacetate and β-hydroxybutyrate) are oxidized in skeletal muscle mainly during fasting as an alternative source of energy to glucose. Prior studies suggest that there is a negative relationship between increased muscle ketolysis and muscle glucose metabolism in mice with obesity and/or type 2 diabetes. Therefore, we investigated the connection between increased ketone body exposure and muscle glucose metabolism by measuring the effect of a 3-hour exposure to ketone bodies on glucose uptake in differentia...
Source: American Journal of Physiology. Cell Physiology - May 6, 2024 Category: Cytology Authors: Hannah Khouri Mathilde Roberge John R Ussher C éline Aguer Source Type: research
Chlorogenic acid and its isomers attenuate NAFLD by mitigating lipid accumulation in oleic acid-induced HepG2 cells and high-fat diet- fed zebrafish
Chem Biodivers. 2024 May 6:e202400564. doi: 10.1002/cbdv.202400564. Online ahead of print.ABSTRACTChlorogenic acid (Chl), isochlorogenic acid A (Isochl A), and isochlorogenic acid B (Isochl B) are naturally occurring phenolic compounds, which have been shown to exert a regulatory effect on lipid metabolism. However, the mechanism underlying this effect remains unclear. Herein, we investigated the inhibitory effects and underlying mechanisms of these three phenolic compounds on oleic acid (OA)-induced HepG2 cells and high-fat diet (HFD)-fed zebrafish. Lipid accumulation and triacylglycerol levels increased in OA-induced cel...
Source: Chemistry and Biodiversity - May 6, 2024 Category: Biochemistry Authors: Fangfang Tie Jin Ding Yidan Gao Honglun Wang Source Type: research
Prenatal High ‐Sucrose Diet Induced Vascular Dysfunction of Renal Interlobar Arteries in the Offspring via PPARγ‐RXRg‐ROS/Akt Signaling
ConclusionMaternal HS during the pregnancy increases PE-mediated vasoconstriction of RIA from adult offspring, which is mainly related to the enhanced Akt and ROS regulated by the weakened PPAR γ-RXRg. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - May 6, 2024 Category: Food Science Authors: Xueqin Feng,
Xinying Liu,
Fuling Wang,
Xiaoyun Zhang,
Liangxi Zhu,
Hua Shu,
Chunxia Wang,
Liting Duan,
Haixia Wang,
Qinggui Ren,
Fangxiang Dong,
Ziteng Zhang,
Dongmei Man,
Miaomiao Qu Tags: Research Article Source Type: research
S ‐Methyl Cysteine Sulfoxide Does Not Ameliorate Weight Gain or Hyperlipidemia in Mice Fed a High‐Fat Diet
ConclusionSMCSO (43 –256 mg kg−1 BW day−1) does not ameliorate metabolic syndrome features in high-fat fed mice. Substantial knowledge gaps remain. Further studies should administer SMCSO separately (i.e., gavage), with metabolic studies exploring tissue levels to better understand its physiological action. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - May 5, 2024 Category: Food Science Authors: Caroline R. Hill,
Armaghan Shafaei,
Vance B. Matthews,
Natalie C. Ward,
Kevin D. Croft,
Joshua R. Lewis,
Jonathan M. Hodgson,
Lois Balmer,
Lauren C. Blekkenhorst Tags: Research Article Source Type: research
USP10 alleviates N ε-carboxymethyl-lysine-induced vascular calcification and atherogenesis in diabetes mellitus by promoting AMPK activation
This study aims to elucidate the role of USP10 in VC development and the underlying regulatory mechanisms. Nε-carboxymethyl lysine (CML) was significantly increased in calcified ateries from diabetic atherosclerosis ApoE-/- mice fed with high-fat diets. CML downregulated USP10 expression in VSMCs and calcified mice coronary arteries, as assessd by Western blotting, RT-qPCR,immunofluorescence and immunohistochemistry. Loss-and gain-of-function experiments were conducted both in vitro and in vivo to verify the biological functions of USP10. Ectopic expression of USP10 mitigated the severity of VC. With regard to the mechani...
Source: Cellular Signalling - May 5, 2024 Category: Cytology Authors: Mayibai Mushajiang Li Yalan Sun Zhen Liu Jia Zhang Lili Wang Zhongqun Source Type: research
Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study
CONCLUSION: This study highlights the potential therapeutic efficacy of C. vulgaris and L. casei in mitigating kidney damage caused by NAFLD. These findings provide valuable insights for developing novel treatment approaches for managing NAFLD and its associated complications.PMID:38704764 | DOI:10.1007/s11033-024-09542-1 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - May 5, 2024 Category: Molecular Biology Authors: Haniyeh Keyghobadi Hadis Bozorgpoursavadjani Farhad Koohpeyma Nazanin Mohammadipoor Marzieh Nemati Farshad Dehghani Iman Jamhiri Gholamhossein Keighobadi Sanaz Dastghaib Source Type: research
Sex-Specific Association Between Childhood Adversity and Accelerated Biological Aging
Adv Sci (Weinh). 2024 May 5:e2309346. doi: 10.1002/advs.202309346. Online ahead of print.ABSTRACTIs childhood adversity associated with biological aging, and if so, does sex modify the association, and do lifestyle and mental health mediate the association? A lifespan analysis is conducted using data on 142 872 participants from the UK Biobank to address these questions. Childhood adversity is assessed through the online mental health questionnaire (2016), including physical neglect, physical abuse, emotional neglect, emotional abuse, sexual abuse, and a cumulative score. Biological aging is indicated by telomere length (T...
Source: Adv Data - May 5, 2024 Category: Epidemiology Authors: Jie Yu Fan Pu Gan Yang Meng Hao Hui Zhang Jingyun Zhang Xingqi Cao Lijun Zhu Yuhui Wan Xiaofeng Wang Zuyun Liu Source Type: research
The physiological and biochemical basis of potency thresholds modeled using human estrogen receptor alpha: implications for identifying endocrine disruptors
Arch Toxicol. 2024 May 5. doi: 10.1007/s00204-024-03723-4. Online ahead of print.ABSTRACTThe endocrine system functions by interactions between ligands and receptors. Ligands exhibit potency for binding to and interacting with receptors. Potency is the product of affinity and efficacy. Potency and physiological concentration determine the ability of a ligand to produce physiological effects. The kinetic behavior of ligand-receptor interactions conforms to the laws of mass action. The laws of mass action define the relationship between the affinity of a ligand and the fraction of cognate receptors that it occupies at any ph...
Source: Archives of Toxicology - May 5, 2024 Category: Toxicology Authors: Christopher J Borgert Lyle D Burgoon John C Matthews Source Type: research
A multicenter, open ‐label, single‐arm trial of the long‐term safety of empagliflozin treatment for refractory diabetes mellitus with insulin resistance (EMPIRE‐02)
ConclusionsEmpagliflozin demonstrated a certain level of safety and efficacy for the treatment of insulin resistance syndrome and lipoatrophic diabetes over 52 weeks, confirming its potential as a therapeutic option. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - May 5, 2024 Category: Endocrinology Authors: Yushi Hirota,
Yasumasa Kakei,
Junta Imai,
Hideki Katagiri,
Ken Ebihara,
Jun Wada,
Junichi Suzuki,
Tatsuhiko Urakami,
Takashi Omori,
Wataru Ogawa Tags: Original Article Source Type: research
Challenges and benefits of using the HeartDiet food frequency questionnaire in cardiac rehabilitation practice
This study aims to evaluate challenges and benefits of its use. The objectives are to: 1) describe HeartDiet responses of patients with ischemic heart disease and discuss HeartDiet’s suitability as a screening tool, 2) discuss whether an abridged version should replace HeartDiet. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - May 5, 2024 Category: Nutrition Authors: Marianne B. Kristensen, Cecilie L. Egholm, Heidi S. Vistisen, Britt Borregaard, Sofie M. Bruvik, Birgitte, M. Bertelsen, Eva Myrup, Tanja Mortensen, Lone Viggers, Rikke E. Mols, Helle Kanstrup, Ann-Dorthe Zwisler Source Type: research
Letter to the Editor: Comment on: “Association of a low-inflammatory diet with survival among adults: The role of cardiometabolic diseases and lifestyle”
(Source: Clinical Nutrition)
Source: Clinical Nutrition - May 5, 2024 Category: Nutrition Authors: Mengqi Qu, Chunling Li, Yun Ye, Feiye Zhu Source Type: research
Metabolic disorders induced the changes in the expressions of TNF α, E-cadherin and ultrastructural alteration of liver cells in a typical animal model of type 2 diabetes: Psammomys obesus
Tissue Cell. 2024 May 3;88:102396. doi: 10.1016/j.tice.2024.102396. Online ahead of print.ABSTRACTBy using a unique animal model of type 2 diabetes mellitus, Psammomys obesus induced by a high-calorie diet (HCD) for nine months, we showed for the first time, in the liver, the impact of inflammation on the remodeling of intercellular junction molecules E-cadherins during the progression of steatohepatitis. Under the effect of HCD, the expressions of immunohistochemical markers, Tumor Necrosis Factor alpha (TNFα) and E-cadherins were inversely correlated. Ultrastructural examination revealed the involvement of destabilizati...
Source: Tissue and Cell - May 4, 2024 Category: Cytology Authors: Ouahiba Sihali-Beloui Djamila Aroune Zineb Bellahreche Nadia Haniche Amel Termeche Nesrine Semiane Aicha Mallek Sergio Marco Source Type: research
