BE-WEL trial (breast: evaluation of weight and exercise for lymphoedema) testing weight control and exercise programmes for women with breast cancer related lymphoedema: a feasibility trial
CONCLUSION: Women with BCRL and overweight and obesity engaged in diet and exercise weight loss programmes. Both weight loss/arm exercise programmes led to modest changes in weight and BCRL. Comparable reductions in BCRL were reported in the weight stable group undertaking arm exercise only. The independent and combined effects of weight loss and exercise on BCRL need further study.TRIAL REGISTRATION: ISRCTN86789850 https://doi.org/10.1186/ISRCTN86789850 , registered 2011.PMID:38758461 | DOI:10.1007/s10549-024-07356-0 (Source: Cancer Control)
Source: Cancer Control - May 17, 2024 Category: Cancer & Oncology Authors: Michelle Harvie Karen Livingstone Debbie McMulllan Mary Pegington Cheryl Lombardelli Judith Adams Maggie Farragher Emma Barrett Nigel Bundred Source Type: research
Mitophagy in health and disease. Molecular mechanisms, regulatory pathways, and therapeutic implications
Apoptosis. 2024 May 17. doi: 10.1007/s10495-024-01977-y. Online ahead of print.ABSTRACTMitophagy, a specialised form of autophagy, selectively targeting damaged or dysfunctional mitochondria, and is crucial for maintaining cellular homeostasis and mitochondrial quality control. Dysregulation of mitophagy contributes to various pathological conditions, including cancer, neurodegenerative and cardiovascular diseases. This review presents a comprehensive analysis of the molecular mechanisms, regulatory pathways, and interplay with other cellular processes governing mitophagy, emphasizing its importance in physiological and pa...
Source: Cancer Control - May 17, 2024 Category: Cancer & Oncology Authors: Mark S D'Arcy Source Type: research
Fiber rich food suppressed airway inflammation, GATA3 + Th2 cells, and FcεRIα+ eosinophils in asthma
CONCLUSION: Convalescent preschool asthmatic children after a symptomatic episode have less serum ß-Hydroxybutyric acid as compared to control and asthmatic children at baseline visit. Fiber rich diet associated with anti-inflammatory effects as well as anti-allergic effects by decreasing Type 2 and IgE mediated immune responses and inducing CD8+ memory effector T cells in a murine model of allergic asthma. Finally, ex vivo infection with Rhinovirus (RV) of total lung cells from asthmatic mice fed with fiber rich food led to a decreased RV load as compared to mice fed with standard food. Moreover, spleen cells derived fro...
Source: Cancer Control - May 17, 2024 Category: Cancer & Oncology Authors: Alicia Schenzel Adriana Geiger Elvedina Nendel Zuqin Yang Susanne Krammer Anna Leberle Ann-Kathrin Brunst Sonja Trump Susanne Mittler Manfred Rauh Carol I Geppert Patrick Tausche Katja Hohenberger Ralf J Rieker Oliver Schieweck Sebastian Zundler Susetta F Source Type: research
β-Hydroxybutyrate Protects Against Cisplatin-Induced Renal Damage via Regulating Ferroptosis
This study provided evidence of the protective effects of β-HB against cisplatin-induced nephrotoxicity and identified inhibited ferroptosis and Camkk2 as potential molecular mechanisms.PMID:38757723 | DOI:10.1080/0886022X.2024.2354918 (Source: Renal Failure)
Source: Renal Failure - May 17, 2024 Category: Urology & Nephrology Authors: Ruixue Tian Shuqin Tang Jingyu Zhao Yajie Hao Limei Zhao Xiutao Han Xingru Wang Lijun Zhang Rongshan Li Xiaoshuang Zhou Source Type: research
Precede-Proceed Model-dominant Nursing Combined With Nutrition Support for Patients Discharged After Hepatobiliary Surgery With T Tube
CONCLUSIONS: Precede-proceed model-dominant nursing combined with nutrition support can significantly improve nutritional status, self-care agency, and QoL and can significantly decrease the incidence of complications for patients discharged after hepatobiliary surgery with a T tube and is worthy of promotion in clinics.PMID:38758148 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - May 17, 2024 Category: Complementary Medicine Authors: Ye Yang Youhong Wang Qi Chen Jingjing Qiu Liping Zhu Source Type: research
Construction and Application of a Health Management Program for Patients with Esophageal and Gastric Variceal Hemorrhage after Endoscopic Treatment
CONCLUSION: The implementation of a health management program in esophageal and gastric variceal hemorrhage patients after endoscopic treatment is helpful to improve the clinical effect of endoscopic treatment, reduce the rebleeding rate and varicose veins, and improve the self-management ability and quality of life of patients, which has important clinical significance.PMID:38758139 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - May 17, 2024 Category: Complementary Medicine Authors: Jingying Shan Liangwei Quan Qingtao Guo Zhenlin Zhang Shuyun Li Hui Wang Source Type: research
Positive correlation of hidradenitis suppurativa and ultra-processed foods consumption
Arch Dermatol Res. 2024 May 17;316(5):172. doi: 10.1007/s00403-024-02947-9.ABSTRACTHidradenitis suppurativa (HS) is a chronic inflammatory skin condition whose pathogenesis is not well established. An association between HS and obesity is suggested but few studies explore specific dietary drivers. Non-Hispanic Blacks have the highest HS prevalence and obesity rates as well as the highest UPFs consumption rates, as opposed to Hispanics who have the lowest prevalence of HS despite having the second highest obesity rates in the US. Instead, Hispanics have the lowest UPFs consumption and highest minimally processed foods consu...
Source: Cell Research - May 17, 2024 Category: Cytology Authors: Nina Rossa Haddad Beita Badiei Kaitlin L Williams Luis A Garza Source Type: research
Altered proteome profiles related to visceral adiposity may mediate the favorable effect of green Mediterranean diet: the DIRECT-PLUS trial
CONCLUSIONS: Proteomics clusters may enhance our understanding of the favorable effect of a green-MED diet that is enriched with polyphenols and low in red/processed meat on visceral adiposity and cardiometabolic risk.PMID:38757229 | DOI:10.1002/oby.24036 (Source: Obesity)
Source: Obesity - May 17, 2024 Category: Eating Disorders & Weight Management Authors: Hila Zelicha Alon Kaplan Anat Yaskolka Meir Ehud Rinott Gal Tsaban Matthias Bl üher Nora Kl öting Uta Ceglarek Berend Isermann Michael Stumvoll Yoash Chassidim Ilan Shelef Frank B Hu Iris Shai Source Type: research
Exploring the link between dietary omega-3 and omega-6 fatty acid intake and rheumatoid arthritis risk: NHANES 1999-2020 study
CONCLUSIONS: The results suggest a negative correlation between the ingestion of n-3 and n-6 fatty acids and the risk of rheumatoid arthritis in US adults.PMID:38757295 | DOI:10.55563/clinexprheumatol/91tmfb (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - May 17, 2024 Category: Rheumatology Authors: Tianlun Kang Yajing Xi Tangliang Qian Siyi Lu Mengmeng Du Xiaojun Shi Xiujuan Hou Source Type: research
Nano-nutraceuticals to Combat Oxidative Stress: Unlocking Newer Paradigms in Adjuvant Therapy
Curr Top Med Chem. 2024 Apr 27. doi: 10.2174/0115680266300779240417104340. Online ahead of print.ABSTRACTNutraceuticals are products that provide both nutritional and therapeutic benefits. These compounds can slow the aging process and provide physiological effects shielding individuals from acute and chronic diseases. People's interests have shifted from allopathic to Ayurvedic to nutraceuticals in recent years. These are often common dietary supplements that have drawn customers worldwide because of their high nutritional safety and lack of adverse effects when used for a long time. Although conventional dosage forms, in...
Source: Current Topics in Medicinal Chemistry - May 17, 2024 Category: Chemistry Authors: None Pooja Manisha Pandey Tarun Kumar Harsh Goswami Rasna Kumari Shivani Kumara Neha Jain Bapi Gorain Pawan Kumar Maurya Viney Chawla Pooja A Chawla Source Type: research
Heavy Metal Exposure-Induced Cardiovascular Diseases: Molecular Mechanisms and Therapeutic Role of Antioxidants
Curr Med Chem. 2024 May 16. doi: 10.2174/0109298673307446240514064253. Online ahead of print.ABSTRACTGlobally, cardiovascular diseases (CVDs) are the main cause of mortality every year worldwide. CVD health is influenced by various health factors, such as blood pressure, cholesterol levels, and glucose control. The main risk factors include smoking, physical activity, food intake, and body mass index. Around 90% of CVDs could be prevented by controlling these risk factors. Heavy metals are indigenous to the environment of the earth. However, modern lifestyles have led to the exploitation of our environment by unconstrained...
Source: Current Medicinal Chemistry - May 17, 2024 Category: Chemistry Authors: Bhuvaneswari Ponnusamy Vishnu Priya Veeraraghavan Isehaq Al-Huseini Choy Ker Woon Selvaraj Jayaraman Srinivasa Rao Sirasanagandla Source Type: research
Dietary Flavonoid Quercetin Supplement Promotes Antiviral Innate Responses Against Vesicular Stomatitis Virus Infection by Reshaping the Bacteriome and Host Metabolome in Mice
ConclusionThis study systematically elucidates the anti-VSV mechanism of quercetin through gut bacteriome and host metabolome assays, offering new insights into VSV treatment and revealing the mechanisms behind a novel disease management strategy using dietary flavonoid supplements. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - May 17, 2024 Category: Food Science Authors: Tingting Li,
Jinfeng Zhu,
Qifeng Yu,
Yinrui Zhu,
Chao Wu,
Xing Zheng,
Nannan Chen,
Pei Pei,
Kai Yang,
Kai Wang,
Lin Hu Tags: Research Article Source Type: research
Academy of Nutrition and Dietetics Board of Directors 2024-2025
This year will be important in Academy history. We are starting a journey of transformative changes for our organization and our profession —and the future of nutrition and dietetics. We have a clear vision of what we want that future to be: expanding opportunities for increased inter-professional collaboration, becoming an advocacy and public policy powerhouse, supporting research to identify the dietary drivers of affordable whole -of-health, and promoting an appreciation of the work of licensed dietitians through modern media. (Source: Journal of the American Dietetic Association)
Source: Journal of the American Dietetic Association - May 17, 2024 Category: Nutrition Tags: From the Academy Source Type: research
GSE240729 Development of a novel non-invasive biomarker panel for hepatic fibrosis in individuals with MASLD
Conclusion& Discussion: Using a translational Approach to identify collagen turnover related proteins indicative of fibrosis, we developed an accurate blood-based biomarker panel to detect and stage hepatic fibrosis in individuals with MASLD. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - May 17, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Association of dietary iron intake with diabetic kidney disease among individuals with diabetes
ConclusionWe found that ≥ 12.59 mg of dietary iron is associated with a lower risk of diabetic kidney disease, especially in those who were male, younger, heavier weight, have better blood sugar control, and those who were ex-smokers. (Source: Endocrine)
Source: Endocrine - May 17, 2024 Category: Endocrinology Source Type: research
