Perceptions of diabetes distress during pregnancy in women with type 1 and type 2 diabetes: a qualitative interpretive description study
Diabetes distress is commonly seen in adults with pre-existing diabetes and is associated with worsened glycemic management and self-management practices. While a majority of women report increased stress duri... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 3, 2024 Category: OBGYN Authors: Holly Tschirhart, Janet Landeen, Jennifer Yost, Kara A. Nerenberg and Diana Sherifali Tags: Research Source Type: research
People with type 1 diabetes exhibit lower exercise capacity compared to a control population with similar physical activity levels
People living with type 1 diabetes (T1D) are encouraged, as the general population, to engage an active lifestyle for the promotion of health care and well-being [1]. Benefits from an active lifestyle are widely demonstrated, including improvements in cardiovascular risk factors, lipid profiles, endothelial function, and insulin requirement, among others [2,3]. Until recently, there was no agreement about the positive effects of physical activity on glycemic control in people with T1D [4]. However, recent studies using continuous glucose monitor sensors (CGMS) indicate improvements in time in range of glucose levels and a ...
Source: Diabetes Research and Clinical Practice - April 2, 2024 Category: Endocrinology Authors: Seraf ín Murillo, Laura Brugnara, Santiago Ríos, Vicent Ribas, Joan-Marc Servitja, Anna Novials Source Type: research
Turning the tides: achieving rapid and safe glucose control in adolescents with suboptimally controlled type 1 diabetes using advanced hybrid closed loop systems
ConclusionsAHCL systems provide a significant, rapid, and safe improvement in glucose control. This marks a pivotal advancement in technology that primarily benefited those who were already compliant. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
AbstractObservational studies showed possible associations between systemic lupus erythematosus and multiple myeloma. However, whether there is a casual relationship between different types of autoimmune diseases (type 1 diabetes mellitus, rheumatoid arthritis, systemic lupus erythematosus, psoriasis, multiple sclerosis, primary sclerosing cholangitis, primary biliary cirrhosis, and juvenile idiopathic arthritis) and multiple myeloma (MM) is not well known. We performed a two-sample Mendelian randomization (MR) study to estimate the casual relationship. Summary-level data of autoimmune diseases were gained from published g...
Source: Clinical and Experimental Medicine - April 2, 2024 Category: Research Source Type: research
Comparison of the optical coherence tomography-angiography (OCT-A) vascular measurements between molecularly confirmed MODY and age-matched healthy controls
ConclusionThe significant CC-VD increase in the MODY group might be associated with hyperglycemia and/or relatively poor and vulnerable peripheral vascular CC perfusion compared to the central. Previous thickness and VD results of childhood or adolescent diabetes were distributed in a wider range, suggesting that various factors, including some not yet clearly defined, may affect the choroidal vasculature independently of glycemia or as a contributing factor. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 2, 2024 Category: Endocrinology Source Type: research
Household food insecurity and associations with hemoglobin A1c and acute diabetes-related complications in youth and young adults with type 1 diabetes: The SEARCH for diabetes in youth study
To examine, among youth and young adults (YYA) with type 1 diabetes (T1D), the association of household food insecurity (HFI) with: 1) HbA1c and 2) episodes of diabetic ketoacidosis (DKA) and severe hypoglycemia. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 2, 2024 Category: Endocrinology Authors: Faisal S. Malik, Angela D. Liese, Alice Ellyson, Lauren A. Reid, Beth A. Reboussin, Katherine A. Sauder, Edward A. Frongillo, Catherine Pihoker, Dana Dabelea, Kristi Reynolds, Elizabeth T. Jensen, Santica Marcovina, Deborah A. Bowlby, Jason A. Mendoza, fo Source Type: research
Information needs on type 1 diabetes mellitus (T1DM) and its management in children and adolescents: a qualitative study
Conclusion
This study provided valuable insights into the information needs related to T1DM and insulin therapy among children and adolescents with T1DM that should be considered by stakeholders in the development of age-appropriate education materials. Such materials will assist children and adolescents to better manage their life-long T1DM condition from adolescence until adulthood. (Source: BMJ Open)
Source: BMJ Open - April 2, 2024 Category: General Medicine Authors: Muhammed Elamin, S., Muhamad Arshad, N. F., Md Redzuan, A., Abdul Aziz, S. A., Hong, J., Chua, X. Y., Bin-Abbas, B. S., Alsagheir, A., Mohamed Shah, N. Tags: Open access, Diabetes and Endocrinology Source Type: research
Irisin attenuates type 1 diabetic cardiomyopathy by anti-ferroptosis via SIRT1-mediated deacetylation of p53
Diabetic cardiomyopathy (DCM) is a serious complication in patients with type 1 diabetes mellitus (T1DM), which still lacks adequate therapy. Irisin, a cleavage peptide off fibronectin type III domain-containi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2024 Category: Cardiology Authors: Yuan-juan Tang, Zhen Zhang, Tong Yan, Ken Chen, Guo-fan Xu, Shi-qiang Xiong, Dai-qian Wu, Jie Chen, Pedro A. Jose, Chun-yu Zeng and Jin-juan Fu Tags: Research Source Type: research
Glycemic Variability and the Thickness of Retinal Layers in Cystic Fibrosis Patients with and without Cystic Fibrosis Related Diabetes
CONCLUSION: Although we investigated a rather small number of patients, we obtained evidence that intraretinal neurodegenerative changes occur in each of our subgroups (CFNG, CFAG, CFRD). Beyond this, our results favor the detrimental role of additional diabetes, as the deviations from healthy controls were most pronounced in the CFRD group and are similar to those seen in patients suffering from type 1 or type 2 diabetes.PMID:38557392 | DOI:10.1080/02713683.2024.2333770 (Source: Cell Research)
Source: Cell Research - April 1, 2024 Category: Cytology Authors: Luisa S Saegebrecht Martin R öhlig Friederike Schaub Manfred Ballmann Oliver Stachs Dagmar-C Fischer Source Type: research
Glycemic Variability and the Thickness of Retinal Layers in Cystic Fibrosis Patients with and without Cystic Fibrosis Related Diabetes
CONCLUSION: Although we investigated a rather small number of patients, we obtained evidence that intraretinal neurodegenerative changes occur in each of our subgroups (CFNG, CFAG, CFRD). Beyond this, our results favor the detrimental role of additional diabetes, as the deviations from healthy controls were most pronounced in the CFRD group and are similar to those seen in patients suffering from type 1 or type 2 diabetes.PMID:38557392 | DOI:10.1080/02713683.2024.2333770 (Source: Current Eye Research)
Source: Current Eye Research - April 1, 2024 Category: Opthalmology Authors: Luisa S Saegebrecht Martin R öhlig Friederike Schaub Manfred Ballmann Oliver Stachs Dagmar-C Fischer Source Type: research
The Role of Selenium Nanoparticles in Addressing Diabetic Complications: A Comprehensive Study
Curr Top Med Chem. 2024 Mar 29. doi: 10.2174/0115680266299494240326083936. Online ahead of print.ABSTRACTDiabetes, as an emerging epidemic, has put forward a significant spotlight on the evolving population worldwide grounded upon the remarkable affliction of healthcare along with economical conflict. Various studies suggested that, in modern society, lack of maintenance of a healthy life style leads to the occurrence of diabetes as insulin resistant, later having a damaging effect on the pancreatic β-cells, suggesting various complications. Furthermore, diabetes management is controversial owing to different opinions bas...
Source: Current Topics in Medicinal Chemistry - April 1, 2024 Category: Chemistry Authors: Siddharth Satpathy Lipsa Leena Panigrahi Manoranjan Arakha Source Type: research
Glycemic Variability and the Thickness of Retinal Layers in Cystic Fibrosis Patients with and without Cystic Fibrosis Related Diabetes
CONCLUSION: Although we investigated a rather small number of patients, we obtained evidence that intraretinal neurodegenerative changes occur in each of our subgroups (CFNG, CFAG, CFRD). Beyond this, our results favor the detrimental role of additional diabetes, as the deviations from healthy controls were most pronounced in the CFRD group and are similar to those seen in patients suffering from type 1 or type 2 diabetes.PMID:38557392 | DOI:10.1080/02713683.2024.2333770 (Source: Current Eye Research)
Source: Current Eye Research - April 1, 2024 Category: Opthalmology Authors: Luisa S Saegebrecht Martin R öhlig Friederike Schaub Manfred Ballmann Oliver Stachs Dagmar-C Fischer Source Type: research
Cross-sectional imaging of the pancreas in diabetes
AbstractDiabetes mellitus presents a global health challenge characterized by dysregulated glucose metabolism and insulin resistance. Pancreas dysfunction contributes to the development and progression of diabetes. Cross-sectional imaging modalities have provided new insight into the structural and functional alterations of the pancreas in individuals with diabetes. This review summarizes MRI and CT studies that characterize pancreas alterations in both type 1 and type 2 diabetes and discusses future applications of these techniques. (Source: Abdominal Imaging)
Source: Abdominal Imaging - April 1, 2024 Category: Radiology Source Type: research
GSE171352 Autophagy regulates glucagon secretion via the beta2-adrenergic pathway
Contributors : Kimitaka Shibue ; Rohit N KulkarniSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAppropriate glucagon secretion from pancreatic alpha cells in response to hypoglycemia is an important component of maintaining glucose homeostasis. Dysregulated glucagon secretion leads to the delayed recovery from a hypoglycemic attack in type 1 diabetes patients which can be lethal. Although elucidating the precise mechanism of glucagon secretion in hypoglycemia is warranted, the underlying mechanism remains poorly understood.The present study provides evidence of the role of autophagy...
Source: GEO: Gene Expression Omnibus - March 31, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Soluble tumor necrosis factor receptor type 1 is an alternative marker of urinary albumin-creatinine ratio and estimated glomerular filtration rate for predicting the decline of renal function in subjects with type 2 diabetes mellitus
CONCLUSION: sTNFR1 could be an alternative marker for identifying patients with diabetes at risk of declining renal function.PMID:38555050 | DOI:10.1016/j.cca.2024.117880 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - March 30, 2024 Category: Chemistry Authors: Li-Hsin Chang Ting-Ting Chang Chia-Huei Chu Chin-Chou Huang Liang-Yu Lin Source Type: research
