A new perspective of frozen shoulder pathology; the interplay between the brain and the immune system
Frozen shoulder (FS), also known as adhesive capsulitis of the shoulder (FS), is a fibrotic inflammatory process of unknown etiology whose main symptoms are pain, stiffness and the loss of joint mobility. These symptoms may be associated with pathologies such as diabetes, Dupuytren’s syndrome and the prevalence of today’s sedentary lifestyle. This literature review provides an overview of the epidemiology and pathogenesis of this pathology, as well as the mechanisms of lowgrade chronic inflammation and infection, insulin resistance, and omics-science associated with it. We also propose a new hypothesis related to the p...
Source: Frontiers in Physiology - March 29, 2024 Category: Physiology Source Type: research
Lipidome characterisation and sex-specific differences in type 1 and type 2 diabetes mellitus
In this study, we evaluated the lipidome alterations caused by type 1 diabetes (T1D) and type 2 diabetes (T2D), by determining lipids significantly associated with diabetes overall and in both sexes, and lipid... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - March 29, 2024 Category: Cardiology Authors: Maria Barranco-Altirriba, N úria Alonso, Ralf J. M. Weber, Gavin R. Lloyd, Marta Hernandez, Oscar Yanes, Jordi Capellades, Andris Jankevics, Catherine Winder, Mireia Falguera, Josep Franch-Nadal, Warwick B Dunn, Alexandre Perera-Lluna, Esmeralda Castelbl Tags: Research Source Type: research
Correction to New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes of the Japan Diabetes Society (English version)
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - March 28, 2024 Category: Endocrinology Tags: Correction Source Type: research
Advancing diabetes treatment: the role of mesenchymal stem cells in islet transplantation
Diabetes mellitus, a prevalent global health challenge, significantly impacts societal and economic well-being. Islet transplantation is increasingly recognized as a viable treatment for type 1 diabetes that aims to restore endogenous insulin production and mitigate complications associated with exogenous insulin dependence. We review the role of mesenchymal stem cells (MSCs) in enhancing the efficacy of islet transplantation. MSCs, characterized by their immunomodulatory properties and differentiation potential, are increasingly seen as valuable in enhancing islet graft survival, reducing immune-mediated rejection, and su...
Source: Frontiers in Immunology - March 28, 2024 Category: Allergy & Immunology Source Type: research
Comparison of Two Estimated Glucose Disposal Rate Methods for Detecting Insulin Resistance in Adults with Type 1 Diabetes Mellitus
Metabolic Syndrome and Related Disorders, Ahead of Print. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - March 28, 2024 Category: Endocrinology Authors: Muhammed Masum Canat Y üksel Altuntaş Source Type: research
Closed-Loop Insulin Delivery May Help Prevent Metabolic Complications During Bariatric Surgery in Patients with Type 1 Diabetes: A Case Report
Diabetes Technology&Therapeutics,Volume 26, Issue 4, Page 279-282, April 2024. (Source: Diabetes Technology)
Source: Diabetes Technology - March 28, 2024 Category: Endocrinology Authors: Erika Cornu Camille Gaulier Pauline Juttet Julie Beauvy Vincent Mezzarobba Anne-Laure Proust Jean-Philippe Le Berre Anne-C écile Paepegaey Source Type: research
Non-cancerous complications in HTLV-1 carriers
Expert Rev Anti Infect Ther. 2024 Mar 27. doi: 10.1080/14787210.2024.2336547. Online ahead of print.ABSTRACTINTRODUCTION: Human T-cell leukemia virus type 1 (HTLV-1) carriers may develop adult T-cell leukemia (ATL), or HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP). The evidence is limited regarding other diseases potentially associated with HTLV-1, such as HTLV-1-associated autoimmune diseases.AREA COVERED: We summarized the available information on complications associated with HTLV-1 infection.EXPERT OPINION: Previous studies showed that HTLV-1 carriers have an increased incidence of collagen dise...
Source: Atherosclerosis - March 27, 2024 Category: Cardiology Authors: Akihiro Ohmoto Shigeo Fuji Source Type: research
PCSK9 plasma concentration is associated with epicardial adipose tissue volume and metabolic control in patients with type 1 diabetes
This study aimed to determine the relationship between PCSK9 levels and epicardial adipose tissue (EAT) volume and cardiometabolic variables in patients with T1D. This was an observational cross-sectional study including 73 patients with T1D. Clinical, biochemical and imaging data were collected. We divided the patients into two groups according to their glycemic control and the EAT index (iEAT) percentile. We performed a correlation analysis between the collected variables and PCSK9 levels; subsequently, we performed a multiple regression analysis with the significant parameters. The mean age was 47.6 ± 8.5 years, 58.9% ...
Source: Atherosclerosis - March 27, 2024 Category: Cardiology Authors: Helena Sard à Cristina Colom Sonia Benitez Gemma Carreras Judit Amig ó Inka Mi ñambres David Vilad és Francisco Blanco-Vaca Jose Lu ís Sanchez-Quesada Antonio P érez Source Type: research
Incidence and risk factors for cancer in people with type 1 diabetes, stratified by stages of diabetic kidney disease: a nationwide Finnish cohort study
Lancet Reg Health Eur. 2024 Mar 16;40:100884. doi: 10.1016/j.lanepe.2024.100884. eCollection 2024 May.ABSTRACTBACKGROUND: Individuals with type 1 diabetes (T1D) have been reported to have increased overall risk of cancer. In addition, individuals with a kidney transplant/transplantation (KT) have markedly increased cancer risk due to chronic use of immunosuppressive agents. However, it has not been elucidated whether the observed excess cancer risk is related to KT or whether diabetic kidney disease (DKD) per se is a risk factor for cancer in individuals with T1D.METHODS: The study included 5035 individuals from the Finnis...
Source: Cancer Control - March 27, 2024 Category: Cancer & Oncology Authors: Maija Feodoroff Valma Harjutsalo Sari M äkimattila Per-Henrik Groop FinnDiane Study Group Source Type: research
Non-cancerous complications in HTLV-1 carriers
Expert Rev Anti Infect Ther. 2024 Mar 27. doi: 10.1080/14787210.2024.2336547. Online ahead of print.ABSTRACTINTRODUCTION: Human T-cell leukemia virus type 1 (HTLV-1) carriers may develop adult T-cell leukemia (ATL), or HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP). The evidence is limited regarding other diseases potentially associated with HTLV-1, such as HTLV-1-associated autoimmune diseases.AREA COVERED: We summarized the available information on complications associated with HTLV-1 infection.EXPERT OPINION: Previous studies showed that HTLV-1 carriers have an increased incidence of collagen dise...
Source: Expert Review of Anti-Infective Therapy - March 27, 2024 Category: Infectious Diseases Authors: Akihiro Ohmoto Shigeo Fuji Source Type: research
Non-cancerous complications in HTLV-1 carriers
Expert Rev Anti Infect Ther. 2024 Mar 27. doi: 10.1080/14787210.2024.2336547. Online ahead of print.ABSTRACTINTRODUCTION: Human T-cell leukemia virus type 1 (HTLV-1) carriers may develop adult T-cell leukemia (ATL), or HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP). The evidence is limited regarding other diseases potentially associated with HTLV-1, such as HTLV-1-associated autoimmune diseases.AREA COVERED: We summarized the available information on complications associated with HTLV-1 infection.EXPERT OPINION: Previous studies showed that HTLV-1 carriers have an increased incidence of collagen dise...
Source: Atherosclerosis - March 27, 2024 Category: Cardiology Authors: Akihiro Ohmoto Shigeo Fuji Source Type: research
Non-cancerous complications in HTLV-1 carriers
Expert Rev Anti Infect Ther. 2024 Mar 27. doi: 10.1080/14787210.2024.2336547. Online ahead of print.ABSTRACTINTRODUCTION: Human T-cell leukemia virus type 1 (HTLV-1) carriers may develop adult T-cell leukemia (ATL), or HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP). The evidence is limited regarding other diseases potentially associated with HTLV-1, such as HTLV-1-associated autoimmune diseases.AREA COVERED: We summarized the available information on complications associated with HTLV-1 infection.EXPERT OPINION: Previous studies showed that HTLV-1 carriers have an increased incidence of collagen dise...
Source: Expert Review of Anti-Infective Therapy - March 27, 2024 Category: Infectious Diseases Authors: Akihiro Ohmoto Shigeo Fuji Source Type: research
Non-cancerous complications in HTLV-1 carriers
Expert Rev Anti Infect Ther. 2024 Apr 1:1-10. doi: 10.1080/14787210.2024.2336547. Online ahead of print.ABSTRACTINTRODUCTION: Human T-cell leukemia virus type 1 (HTLV-1) carriers may develop adult T-cell leukemia (ATL), or HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP). The evidence is limited regarding other diseases potentially associated with HTLV-1, such as HTLV-1-associated autoimmune diseases.AREA COVERED: We summarized the available information on complications associated with HTLV-1 infection.EXPERT OPINION: Previous studies showed that HTLV-1 carriers have an increased incidence of collagen ...
Source: Expert Review of Anti-Infective Therapy - March 27, 2024 Category: Infectious Diseases Authors: Akihiro Ohmoto Shigeo Fuji Source Type: research
