Type 1 diabetes care delivery in Yaounde, Cameroon: Social and political representations
CONCLUSION: Patients and families mobilise experience and lay knowledge to complement biomedical knowledge, but top-down policy and clinical practice limit their active engagement in T1D care.Contribution: Children with T1D and their families, policy makers, healthcare professionals, and civil society have new opportunities to contribute to person-centred care, as advocated by the Sustainable Development Goals.PMID:38572859 | DOI:10.4102/phcfm.v16i1.4229 (Source: Primary Care)
Source: Primary Care - April 4, 2024 Category: Primary Care Authors: Herv é B Djiofack Kentsop Christina Zarowsky Julia E Von Oettingen Source Type: research

A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes
J Proteomics. 2024 Apr 2:105167. doi: 10.1016/j.jprot.2024.105167. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) poses a significant health challenge for individuals with diabetes. At its initial stages, DKD often presents asymptomatically, and the standard for non-invasive diagnosis, the albumin-creatinine ratio (ACR), employs discrete categorizations (normal, microalbuminuria, macroalbuminuria) with limitations in sensitivity and specificity across diverse population cohorts. Single biomarker reliance further restricts the predictive value in clinical settings. Given the escalating prevalence of diabetes, o...
Source: Journal of Proteomics - April 4, 2024 Category: Biochemistry Authors: Jeremy Altman Shan Bai Sharad Purohit John White Dennis Steed Su Liu Diane Hopkins Jin-Xiong She Ashok Sharma Wenbo Zhi Source Type: research

A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes
J Proteomics. 2024 Apr 2:105167. doi: 10.1016/j.jprot.2024.105167. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) poses a significant health challenge for individuals with diabetes. At its initial stages, DKD often presents asymptomatically, and the standard for non-invasive diagnosis, the albumin-creatinine ratio (ACR), employs discrete categorizations (normal, microalbuminuria, macroalbuminuria) with limitations in sensitivity and specificity across diverse population cohorts. Single biomarker reliance further restricts the predictive value in clinical settings. Given the escalating prevalence of diabetes, o...
Source: Journal of Proteomics - April 4, 2024 Category: Biochemistry Authors: Jeremy Altman Shan Bai Sharad Purohit John White Dennis Steed Su Liu Diane Hopkins Jin-Xiong She Ashok Sharma Wenbo Zhi Source Type: research

A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes
J Proteomics. 2024 Apr 2:105167. doi: 10.1016/j.jprot.2024.105167. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) poses a significant health challenge for individuals with diabetes. At its initial stages, DKD often presents asymptomatically, and the standard for non-invasive diagnosis, the albumin-creatinine ratio (ACR), employs discrete categorizations (normal, microalbuminuria, macroalbuminuria) with limitations in sensitivity and specificity across diverse population cohorts. Single biomarker reliance further restricts the predictive value in clinical settings. Given the escalating prevalence of diabetes, o...
Source: Journal of Proteomics - April 4, 2024 Category: Biochemistry Authors: Jeremy Altman Shan Bai Sharad Purohit John White Dennis Steed Su Liu Diane Hopkins Jin-Xiong She Ashok Sharma Wenbo Zhi Source Type: research

A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes
J Proteomics. 2024 Apr 2:105167. doi: 10.1016/j.jprot.2024.105167. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) poses a significant health challenge for individuals with diabetes. At its initial stages, DKD often presents asymptomatically, and the standard for non-invasive diagnosis, the albumin-creatinine ratio (ACR), employs discrete categorizations (normal, microalbuminuria, macroalbuminuria) with limitations in sensitivity and specificity across diverse population cohorts. Single biomarker reliance further restricts the predictive value in clinical settings. Given the escalating prevalence of diabetes, o...
Source: Journal of Proteomics - April 4, 2024 Category: Biochemistry Authors: Jeremy Altman Shan Bai Sharad Purohit John White Dennis Steed Su Liu Diane Hopkins Jin-Xiong She Ashok Sharma Wenbo Zhi Source Type: research

A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes
J Proteomics. 2024 Apr 2;300:105167. doi: 10.1016/j.jprot.2024.105167. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) poses a significant health challenge for individuals with diabetes. At its initial stages, DKD often presents asymptomatically, and the standard for non-invasive diagnosis, the albumin-creatinine ratio (ACR), employs discrete categorizations (normal, microalbuminuria, macroalbuminuria) with limitations in sensitivity and specificity across diverse population cohorts. Single biomarker reliance further restricts the predictive value in clinical settings. Given the escalating prevalence of diabete...
Source: Journal of Proteomics - April 4, 2024 Category: Biochemistry Authors: Jeremy Altman Shan Bai Sharad Purohit John White Dennis Steed Su Liu Diane Hopkins Jin-Xiong She Ashok Sharma Wenbo Zhi Source Type: research

A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes
J Proteomics. 2024 Apr 2;300:105167. doi: 10.1016/j.jprot.2024.105167. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) poses a significant health challenge for individuals with diabetes. At its initial stages, DKD often presents asymptomatically, and the standard for non-invasive diagnosis, the albumin-creatinine ratio (ACR), employs discrete categorizations (normal, microalbuminuria, macroalbuminuria) with limitations in sensitivity and specificity across diverse population cohorts. Single biomarker reliance further restricts the predictive value in clinical settings. Given the escalating prevalence of diabete...
Source: Journal of Proteomics - April 4, 2024 Category: Biochemistry Authors: Jeremy Altman Shan Bai Sharad Purohit John White Dennis Steed Su Liu Diane Hopkins Jin-Xiong She Ashok Sharma Wenbo Zhi Source Type: research

Prevalence of Type 1 Diabetes Among US Children and Adults by Age, Sex, Race, and Ethnicity
This study uses data from the 2019 to 2022 cycles of the National Health Interview Survey to estimate the prevalence of type 1 diabetes among US youths and adults. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 4, 2024 Category: General Medicine Source Type: research

Insulin Analogs and the Mode of Insulin Delivery: Recent Advances and Challenges
Curr Pharm Biotechnol. 2024 Apr 2. doi: 10.2174/0113892010287216240324050651. Online ahead of print.ABSTRACTDiabetes is a medical condition associated with impaired glucose regulation caused either due to insufficient insulin production or resistance to insulin (Type 2 diabetes, gestational diabetes) or the absence of insulin through the selective killing of beta cells in the pancreas (Type 1 diabetes). Irregular insulin production leads to various health complications. To prevent such complications, patients must adhere to medical recommendations before availing of any advanced insulin therapy(ies), considered productive ...
Source: Current Pharmaceutical Biotechnology - April 3, 2024 Category: Biotechnology Authors: Medha Bhagi Jasmine Kaur Arti Dhar Audesh Bhat Source Type: research

Insulin Analogs and the Mode of Insulin Delivery: Recent Advances and Challenges
Curr Pharm Biotechnol. 2024 Apr 2. doi: 10.2174/0113892010287216240324050651. Online ahead of print.ABSTRACTDiabetes is a medical condition associated with impaired glucose regulation caused either due to insufficient insulin production or resistance to insulin (Type 2 diabetes, gestational diabetes) or the absence of insulin through the selective killing of beta cells in the pancreas (Type 1 diabetes). Irregular insulin production leads to various health complications. To prevent such complications, patients must adhere to medical recommendations before availing of any advanced insulin therapy(ies), considered productive ...
Source: Current Pharmaceutical Biotechnology - April 3, 2024 Category: Biotechnology Authors: Medha Bhagi Jasmine Kaur Arti Dhar Audesh Bhat Source Type: research

Serum carnosinase 1, an early indicator for incident microalbuminuria in type 1 diabetes
DiscussionSerum CN1 could predict incident microalbuminuria and may be used as a novel parameter to identify patients at risk for DKD. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 3, 2024 Category: Endocrinology Source Type: research

Perceptions of diabetes distress during pregnancy in women with type 1 and type 2 diabetes: a qualitative interpretive description study
Diabetes distress is commonly seen in adults with pre-existing diabetes and is associated with worsened glycemic management and self-management practices. While a majority of women report increased stress duri... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 3, 2024 Category: OBGYN Authors: Holly Tschirhart, Janet Landeen, Jennifer Yost, Kara A. Nerenberg and Diana Sherifali Tags: Research Source Type: research

People with type 1 diabetes exhibit lower exercise capacity compared to a control population with similar physical activity levels
People living with type 1 diabetes (T1D) are encouraged, as the general population, to engage an active lifestyle for the promotion of health care and well-being [1]. Benefits from an active lifestyle are widely demonstrated, including improvements in cardiovascular risk factors, lipid profiles, endothelial function, and insulin requirement, among others [2,3]. Until recently, there was no agreement about the positive effects of physical activity on glycemic control in people with T1D [4]. However, recent studies using continuous glucose monitor sensors (CGMS) indicate improvements in time in range of glucose levels and a ...
Source: Diabetes Research and Clinical Practice - April 2, 2024 Category: Endocrinology Authors: Seraf ín Murillo, Laura Brugnara, Santiago Ríos, Vicent Ribas, Joan-Marc Servitja, Anna Novials Source Type: research

Turning the tides: achieving rapid and safe glucose control in adolescents with suboptimally controlled type 1 diabetes using advanced hybrid closed loop systems
ConclusionsAHCL systems provide a significant, rapid, and safe improvement in glucose control. This marks a pivotal advancement in technology that primarily benefited those who were already compliant. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research

The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
AbstractObservational studies showed possible associations between systemic lupus erythematosus and multiple myeloma. However, whether there is a casual relationship between different types of autoimmune diseases (type 1 diabetes mellitus, rheumatoid arthritis, systemic lupus erythematosus, psoriasis, multiple sclerosis, primary sclerosing cholangitis, primary biliary cirrhosis, and juvenile idiopathic arthritis) and multiple myeloma (MM) is not well known. We performed a two-sample Mendelian randomization (MR) study to estimate the casual relationship. Summary-level data of autoimmune diseases were gained from published g...
Source: Clinical and Experimental Medicine - April 2, 2024 Category: Research Source Type: research