Vitamin D efficacy in type 1 and type 2 diabetes
AbstractIt is well known that vitamin D has a profound effect on calcium and bone metabolism, but its influence on other organs (extraskeletal effect) has been proposed. Consistently, vitamin D deficiency is associated with an increased incidence of various diseases, including type 1 and type 2 diabetes, as reported by many observational studies. However, there has been no consensus on whether vitamin D deficiency is a causative factor in the incidence of diabetes mellitus. There have been no randomized controlled trials (RCTs) aimed at preventing the onset of type 1 diabetes with vitamin D intake. In addition, the results...
Source: Journal of Bone and Mineral Metabolism - April 25, 2024 Category: Orthopaedics Source Type: research
Stroke incidence increases with diabetic retinopathy severity and macular edema in type 1 diabetes
As the retina is suggested to mirror the brain, we hypothesized that diabetic retinopathy and macular edema are indicative of stroke risk in type 1 diabetes and sought to assess this association in individuals... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 25, 2024 Category: Cardiology Authors: Marika I Eriksson, Kustaa Hietala, Paula Summanen, Valma Harjutsalo, Jukka Putaala, Anni Ylinen, Stefanie H ägg-Holmberg, Per-Henrik Groop and Lena M Thorn Tags: Research Source Type: research
Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK
CONCLUSIONS: The HZ incidence rate in Europe increased with age and varied across high-risk populations, with high rates for solid organ and stem cell transplants, cancer, and rheumatoid arthritis. Most studies were retrospective with methodological differences affecting generalizability and comparability. Future studies should stratify data by IC population, age, sex, severity, medication, and study timeframe.PMID:38656653 | DOI:10.1007/s40121-024-00963-w (Source: Herpes)
Source: Herpes - April 24, 2024 Category: Infectious Diseases Authors: Alen Marijam Nikki Vroom Amit Bhavsar Inga Posiuniene Nicolas Lecrenier Hilde Vroling Source Type: research
Autonomous artificial intelligence versus teleophthalmology for diabetic retinopathy
Conclusions: The comparison between the diagnosis provided by artificial intelligence based automated software and the reference clinical diagnosis showed that they can work at a level of sensitivity that is similar to that achieved by experts.PMID:38656241 | DOI:10.1177/11206721241248856 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 24, 2024 Category: Opthalmology Authors: Donatella Musetti Carlo Alberto Cutolo Monica Bonetto Mauro Giacomini Davide Maggi Giorgio Luciano Viviani Ilaria Gandin Carlo Enrico Traverso Massimo Nicol ò Source Type: research
Classroom as the Site for Type 1 Diabetes Self-Care Activities
Indian Pediatr. 2024 Apr 22:S097475591600636. Online ahead of print.ABSTRACTChildren and adolescents with Type 1 diabetes (T1D) require bolus insulin before each meal, necessitating self-care activities including blood glucose checking to determine insulin dose (or check for hypoglycemia) and injecting insulin during school hours. Though these activities are essential for optimizing glycemic control, they are met with reluctance from parents, the child, school authorities, and sometimes peers. This requires ongoing education and support for the child, school staff, and other students, by the diabetes care team. Many proble...
Source: Indian Pediatrics - April 24, 2024 Category: Pediatrics Authors: Anju Virmani Source Type: research
Long-term assessment of the NHS hybrid closed-loop real-world study on glycaemic outcomes, time-in-range, and quality of life in children and young people with type 1 diabetes
This study aimed to assess the efficacy of HCLs at 12 months post-initiation on glycated haemoglobin (HbA1c), time-in-range (TIR), hypoglycaemia frequency, and quality of life measures among children and young people (CYP) with type 1 diabetes mellitus (T1DM) and their caregivers in a real-world setting. Conducted between August 1, 2021, and December 10, 2022, the prospective recruitment took place in eight paediatric diabetes centres across England under the National Health Service England's (NHSE) HCL pilot real-world study. A cohort of 251 CYP (58% males, mean age 12.3 years) with T1DM participated (89% white, 3% Asian,...
Source: Molecular Medicine - April 24, 2024 Category: Molecular Biology Authors: Sze May Ng Neil P Wright Diana Yardley Fiona Campbell Tabitha Randell Nicola Trevelyan Atrayee Ghatak Peter C Hindmarsh Source Type: research
Classroom as the Site for Type 1 Diabetes Self-Care Activities
Indian Pediatr. 2024 Apr 22:S097475591600636. Online ahead of print.ABSTRACTChildren and adolescents with Type 1 diabetes (T1D) require bolus insulin before each meal, necessitating self-care activities including blood glucose checking to determine insulin dose (or check for hypoglycemia) and injecting insulin during school hours. Though these activities are essential for optimizing glycemic control, they are met with reluctance from parents, the child, school authorities, and sometimes peers. This requires ongoing education and support for the child, school staff, and other students, by the diabetes care team. Many proble...
Source: Indian Pediatrics - April 24, 2024 Category: Pediatrics Authors: Anju Virmani Source Type: research
Classroom as the Site for Type 1 Diabetes Self-Care Activities
Indian Pediatr. 2024 Apr 22:S097475591600636. Online ahead of print.ABSTRACTChildren and adolescents with Type 1 diabetes (T1D) require bolus insulin before each meal, necessitating self-care activities including blood glucose checking to determine insulin dose (or check for hypoglycemia) and injecting insulin during school hours. Though these activities are essential for optimizing glycemic control, they are met with reluctance from parents, the child, school authorities, and sometimes peers. This requires ongoing education and support for the child, school staff, and other students, by the diabetes care team. Many proble...
Source: Indian Pediatrics - April 24, 2024 Category: Pediatrics Authors: Anju Virmani Source Type: research
Classroom as the Site for Type 1 Diabetes Self-Care Activities
Indian Pediatr. 2024 Apr 22:S097475591600636. Online ahead of print.ABSTRACTChildren and adolescents with Type 1 diabetes (T1D) require bolus insulin before each meal, necessitating self-care activities including blood glucose checking to determine insulin dose (or check for hypoglycemia) and injecting insulin during school hours. Though these activities are essential for optimizing glycemic control, they are met with reluctance from parents, the child, school authorities, and sometimes peers. This requires ongoing education and support for the child, school staff, and other students, by the diabetes care team. Many proble...
Source: Indian Pediatrics - April 24, 2024 Category: Pediatrics Authors: Anju Virmani Source Type: research
Exogenous Insulin Antibody Syndrome (EIAS) Presenting in an Elderly, Long-Term Patient with Type 1 Diabetes Mellitus that Resolved with Low-Cost Outpatient Therapy with Mycophenolate Mofetil and Regular Insulin by Pump
AbstractExogenous insulin antibody syndrome (EIAS) has until recently been a rarely described complication of exogenous insulin therapy. EIAS results not only in hyperglycemia, but also in hypoglycemia and occasionally in ketoacidosis (DKA). The incidence of EIAS is increasing probably due to an overall increase in autoimmunity associated with the coronavirus disease 2019 (Covid-19) epidemic resulting in increasing binding of insulin by antibodies. Herein, we describe a case of EIAS occurring in an elderly patient with longstanding type 1 diabetes mellitus (T1DM) who had progressive loss of glycemic control. It responded p...
Source: Diabetes Therapy - April 24, 2024 Category: Endocrinology Source Type: research
Perceptions Related to Death in Adolescents and Their Parents During the Management of Type 1 Diabetes: A Thematic Analysis
Type 1 diabetes (T1D) is associated with an increased risk of premature death compared to those without T1D, yet perceptions of dying have not been well studied. The purpose of this secondary analysis of existing data was to explore the fears of adolescents with T1D and their parents related to the possibility of death due to T1D. (Source: Journal of Pediatric Health Care)
Source: Journal of Pediatric Health Care - April 24, 2024 Category: Pediatrics Authors: Pamela Farthing, Jill Bally, Donna C. Rennie Tags: Qualitative Source Type: research
Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK
ConclusionsThe HZ incidence rate in Europe increased with age and varied across high-risk populations, with high rates for solid organ and stem cell transplants, cancer, and rheumatoid arthritis. Most studies were retrospective with methodological differences affecting generalizability and comparability. Future studies should stratify data by IC population, age, sex, severity, medication, and study timeframe. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - April 24, 2024 Category: Infectious Diseases Source Type: research
Exogenous Insulin Antibody Syndrome (EIAS) Presenting in an Elderly, Long-Term Patient with Type 1 Diabetes Mellitus that Resolved with Low-Cost Outpatient Therapy with Mycophenolate Mofetil and Regular Insulin by Pump
AbstractExogenous insulin antibody syndrome (EIAS) has until recently been a rarely described complication of exogenous insulin therapy. EIAS results not only in hyperglycemia, but also in hypoglycemia and occasionally in ketoacidosis (DKA). The incidence of EIAS is increasing probably due to an overall increase in autoimmunity associated with the coronavirus disease 2019 (Covid-19) epidemic resulting in increasing binding of insulin by antibodies. Herein, we describe a case of EIAS occurring in an elderly patient with longstanding type 1 diabetes mellitus (T1DM) who had progressive loss of glycemic control. It responded p...
Source: Diabetes Therapy - April 24, 2024 Category: Endocrinology Source Type: research
Mendelian randomisation highlights type 1 diabetes as a causal determinant of idiopathic pulmonary fibrosis
It is unclear whether type 1 diabetes (T1D) causes idiopathic pulmonary fibrosis (IPF), despite observational research linking the two conditions. Therefore, our study aimed to examine the causal link between ... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - April 24, 2024 Category: Endocrinology Authors: Xinlai Ma, Yang Zhang, Fan Wu, Xue Liu and Wei Zhang Tags: Research Source Type: research
Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK
ConclusionsThe HZ incidence rate in Europe increased with age and varied across high-risk populations, with high rates for solid organ and stem cell transplants, cancer, and rheumatoid arthritis. Most studies were retrospective with methodological differences affecting generalizability and comparability. Future studies should stratify data by IC population, age, sex, severity, medication, and study timeframe. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - April 24, 2024 Category: Infectious Diseases Source Type: research
