Dengue-related acute liver failure —A scoping review
AbstractInfection by dengue virus is common in tropical countries. Hepatic involvement in dengue can range from asymptomatic elevation of transaminases to life-threatening acute liver failure (ALF). Dengue-related ALF (DALF) is responsible for significant morbidity and mortality, especially in Southeast Asia. However, there is a scarcity of literature on DALF, necessitating a thorough examination of its clinical determinants and management strategies. All relevant studies related to DALF were reviewed until December 2023. Case reports, case series and studies reporting ALF in dengue infection were included. Demographics, c...
Source: Indian Journal of Gastroenterology - April 30, 2024 Category: Gastroenterology Source Type: research

Viruses, Vol. 16, Pages 703: Winged Threat on the Offensive: A Literature Review Due to the First Identification of Aedes japonicus in Poland
Niemiec Genetic studies preceded by the observation of an unknown mosquito species in Mikołów (Poland) confirmed that it belongs to a new invasive species in Polish fauna, Aedes japonicus (Theobald, 1901), a known vector for numerous infectious diseases. Ae. japonicus is expanding its geographical presence, raising concerns about potential disease transmission given its vector competence for chikungunya virus, dengue virus, West Nile virus, and Zika virus. This first genetically confirmed identification of Ae. japonicus in Poland initiates a comprehensive review of the literature on Ae. japo...
Source: Viruses - April 29, 2024 Category: Virology Authors: Marcin Gierek Gabriela Ocha ła-Gierek Andrzej J ózef Woźnica Grzegorz Zale śny Alicja Jarosz Pawe ł Niemiec Tags: Review Source Type: research

Revealing the microbiome diversity and biocontrol potential of field < i > Aedes ssp < /i > .: Implications for disease vector management
by Apolinar M. Hern ández, Luis D. Alcaraz, Cristóbal Hernández-Álvarez, Miguel F. Romero, Angélica Jara-Servín, Hugo Barajas, Carlos M. . Ramírez, Mariana Peimbert The mosquitoAedes spp. holds important relevance for human and animal health, as it serves as a vector for transmitting multiple diseases, including dengue and Zika virus. The microbiome ’s impact on its host’s health and fitness is well known. However, most studies on mosquito microbiomes have been conducted in laboratory settings. We explored the mixed microbial communities withinAedes spp., utilizing the 16S rRNA gene for diversity analysis and s...
Source: PLoS One - April 29, 2024 Category: Biomedical Science Authors: Apolinar M. Hern ández Source Type: research

Projection of dengue fever transmissibility under climate change in South and Southeast Asian countries
In conclusion, the change of peak DF transmission potential and disease outbreak duration would vary across locations, particularly under middle-to-high greenhouse gas emission scenarios. Interventions should be considered to slow down global warming as well as the potential increase in DF transmissibility in some locations of South and Southeast Asia. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 29, 2024 Category: Tropical Medicine Authors: Yawen Wang Source Type: research

Behaviour and distribution of < i > Aedes aegypti < /i > mosquitoes and their relation to dengue incidence in two transmission hotspots in coastal Ecuador
Conclusions/SignificanceAedes aegypti abundance was significantly higher in urban than peri-urban neighbourhoods, and their resting behaviour varied between study sites. This fine-scale spatial heterogeneity inAe.aegypti abundance and behaviour could generate site-specific variation in human exposure and the effectiveness of indoor-based interventions. The trap-dependent nature of associations betweenAedes abundance and local DENV incidence indicates further work is needed to identify robust entomological indicators of infection risk. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 29, 2024 Category: Tropical Medicine Authors: Leonardo D. Ortega-L ópez Source Type: research

New in the tropics: Safety concerns of the novel Butantan-Dengue vaccine for dengue prevention in tropical countries
Trop Doct. 2024 Apr 28:494755241250083. doi: 10.1177/00494755241250083. Online ahead of print.NO ABSTRACTPMID:38679746 | DOI:10.1177/00494755241250083 (Source: Tropical Doctor)
Source: Tropical Doctor - April 28, 2024 Category: Tropical Medicine Authors: Isaac K S Ng Wilson G W Goh Desmond B Teo Source Type: research

New in the tropics: Safety concerns of the novel Butantan-Dengue vaccine for dengue prevention in tropical countries
Trop Doct. 2024 Apr 28:494755241250083. doi: 10.1177/00494755241250083. Online ahead of print.NO ABSTRACTPMID:38679746 | DOI:10.1177/00494755241250083 (Source: Tropical Doctor)
Source: Tropical Doctor - April 28, 2024 Category: Tropical Medicine Authors: Isaac K S Ng Wilson G W Goh Desmond B Teo Source Type: research

New in the tropics: Safety concerns of the novel Butantan-Dengue vaccine for dengue prevention in tropical countries
Trop Doct. 2024 Apr 28:494755241250083. doi: 10.1177/00494755241250083. Online ahead of print.NO ABSTRACTPMID:38679746 | DOI:10.1177/00494755241250083 (Source: Tropical Doctor)
Source: Tropical Doctor - April 28, 2024 Category: Tropical Medicine Authors: Isaac K S Ng Wilson G W Goh Desmond B Teo Source Type: research

New in the tropics: Safety concerns of the novel Butantan-Dengue vaccine for dengue prevention in tropical countries
Trop Doct. 2024 Apr 28:494755241250083. doi: 10.1177/00494755241250083. Online ahead of print.NO ABSTRACTPMID:38679746 | DOI:10.1177/00494755241250083 (Source: Tropical Doctor)
Source: Tropical Doctor - April 28, 2024 Category: Tropical Medicine Authors: Isaac K S Ng Wilson G W Goh Desmond B Teo Source Type: research

Chemical control of medically important arthropods in Panama: A systematic literature review of historical efforts
Acta Trop. 2024 Apr 25:107217. doi: 10.1016/j.actatropica.2024.107217. Online ahead of print.ABSTRACTVector-borne diseases are a major source of morbidity in Panama. Herein, we describe historical usage patterns of synthetic insecticides to control arthropod disease vectors in this country. We examine the influence of interventions by vector control programs on the emergence of insecticide resistance. Chemical control has traditionally focused on two mosquito species: Anopheles albimanus, a major regional malaria vector, and Aedes aegypti, a historical vector of yellow fever, and current vector of dengue, chikungunya, and ...
Source: Acta Tropica - April 27, 2024 Category: Infectious Diseases Authors: Anyi Tu ñon Joel Garc ía Lorenzo C áceres Carrera Luis Fernando Chaves Audrey E Lenhart Jose R Loaiza Source Type: research

Bioactive components in Psidium guajava extracts elicit biotoxic attributes and distinct antioxidant enzyme modulation in the larvae of vectors of lymphatic filariasis and dengue
This study investigated the larvicidal potential of aqueous, methanol, and ethylacetate extracts of Guava (Psidium guajava) against Aedes aegypti and Culex quinquefasciatus larvae. Functional group and phytochemical characterization were performed using Fourier-Transform Infrared Spectroscopy (FTIR) and GC-MS analysis to identify the bioactive compounds in the extracts. Larval bioassays were conducted using WHO standard procedures at concentrations of 12.5, 25, 50, 125, and 250 mg/L, and mortality was recorded after 24, 48, and 72 h. Additionally, antioxidant enzyme profiles in the larvae were studied. All of the solvent e...
Source: Experimental Parasitology - April 27, 2024 Category: Parasitology Authors: Harun K Aremu Olu I Oyewole Adeola Adenmosun Lateefah Oyafajo Zarat O Iwalewa Adenike Ademola Luqmon A Azeez Monsuru A Adeleke Source Type: research

Chemical control of medically important arthropods in Panama: A systematic literature review of historical efforts
Acta Trop. 2024 Apr 25:107217. doi: 10.1016/j.actatropica.2024.107217. Online ahead of print.ABSTRACTVector-borne diseases are a major source of morbidity in Panama. Herein, we describe historical usage patterns of synthetic insecticides to control arthropod disease vectors in this country. We examine the influence of interventions by vector control programs on the emergence of insecticide resistance. Chemical control has traditionally focused on two mosquito species: Anopheles albimanus, a major regional malaria vector, and Aedes aegypti, a historical vector of yellow fever, and current vector of dengue, chikungunya, and ...
Source: Acta Tropica - April 27, 2024 Category: Infectious Diseases Authors: Anyi Tu ñon Joel Garc ía Lorenzo C áceres Carrera Luis Fernando Chaves Audrey E Lenhart Jose R Loaiza Source Type: research

GSE264625 Functional genomics screens reveal a role for TBC1D24 and SV2B in antibody-dependent enhancement of dengue virus infection.
Contributors : Laura Belmont ; Maya Contreras ; Catiana H Cartwright-Acar ; Caleb D Marceau ; Aditi Agrawal ; Lisa M Levoir ; Jay Lubow ; Leslie GooSeries Type : OtherOrganism : Homo sapiensDengue virus (DENV) can hijack non-neutralizing IgG antibodies to facilitate its uptake into target cells expressing Fc gamma receptors (FcgR) - a process known as antibody-dependent enhancement (ADE) of infection. Beyond a requirement for FcgR, host dependency factors for this non-canonical infection route remain unknown. To identify cellular factors exclusively required for ADE, here, we performed CRISPR knockout screens in an in...
Source: GEO: Gene Expression Omnibus - April 27, 2024 Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research

Changing etiological spectrum of acute liver failure
ConclusionsThe most common cause for ALF was hepatitis A virus, followed by hepatitis B virus, while in ALF mimics it was malaria followed by dengue fever, in our study. Patients of ALF mimics can have similar presentation, but a high index of suspicion and awareness is required to identify the common infectious ALF mimics for early diagnosis.Graphical Abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 27, 2024 Category: Gastroenterology Source Type: research